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Proteins are complex molecules that are made up of amino acids. They can be found in every cell in the body, and carry out vital processes that keep human beings alive. Mutations in proteins can lead to a multitude of diseases, the most common being cancer.

Scientists reveal how critical enzyme in the cell works

S-acylation is the process of chemically linking a lipid to protein via a thioester bond. It is an important process of the cell that regulates the localization and function of numerous proteins.

12 Mar 2021

Researchers generate thyroid mini-organs in the lab

Hormones produced by the thyroid gland are essential regulators of organ function. The absence of these hormones either through thyroid dysfunction due to, for example, irradiation, thyroid cancer or autoimmune disease or thyroidectomy leads to symptoms like fatigue, feeling cold, constipation, and weight gain.

12 Mar 2021

Study reveals mechanisms behind the activation of MRN complex

Researchers from the Tokyo Institute of Technology have revealed mechanisms behind the stimulation of the MRN complex—the DNA scissors of the cells.

11 Mar 2021

Alzheimer’s proteins linked to age-related vision loss

A recently published study has demonstrated a close correlation between proteins linked to age-related vision loss and Alzheimer’s disease.

11 Mar 2021

Study on AEG12 mosquito protein could lead to therapeutics against deadly viruses

Researchers have found that AEG12, a mosquito protein, strongly suppresses the class of viruses causing dengue, yellow fever, Zika, and West Nile.

11 Mar 2021

Study reveals mechanism that regulates genes on sex chromosomes

In the human population, males have one X and one Y chromosomes and females have two X chromosomes. As a result, somatic cells have unique mechanisms that maintain the same gene expression levels on the X chromosome between both genders.

10 Mar 2021

Spraying leaves with vitamin C can dramatically increase protein production

The production of high-value pharmaceutical proteins in plants provides benefits over other manufacturing techniques.

10 Mar 2021

Study offers fresh insights into infection process during spaceflight

Astronauts face many challenges to their health, due to the exceptional conditions of spaceflight. Among these are a variety of infectious microbes that can attack their suppressed immune systems.

10 Mar 2021

Comprehensive mutation map helps better understand the biological processes underlying Alzheimer's

A study published in the journal eLife made all the possible mutations in the amyloid beta peptide and tested how they influence its aggregation into plaques, a pathological hallmark of Alzheimer's disease.

10 Mar 2021

Study identifies genes responsible for peach's tolerance to stress

A Boyce Thompson Institute-led team has identified genes enabling peaches and their wild relatives to tolerate stressful conditions -- findings that could help the domesticated peach adapt to climate change.

10 Mar 2021

Regenerating bone marrow after chemotherapy

In this interview, AZoLifeSciences speaks to Professor Masaru Ishii about his latest research that investigated how bone marrow regenerates after chemotherapy.

From Osaka University 10 Mar 2021

New substance could improve the treatment of drug-resistant cancers

A new substance could improve the treatment of persistent cancers. Researchers at Martin Luther University Halle-Wittenberg and the University of Greifswald have developed a new inhibitor that makes drug-resistant tumor cells respond again to chemotherapy.

9 Mar 2021

Catechin-type flavonoid compounds in tea relax blood vessels by activating ion channel proteins

A new study from the University of California, Irvine shows that compounds in both green and black tea relax blood vessels by activating ion channel proteins in the blood vessel wall.

9 Mar 2021

Fluorescent chemical dye helps track specific motor protein within cells

A cell can stay alive only when it supplies all the required energy elements to its various organelles and these elements are formed in the Golgi apparatus.

8 Mar 2021

Mutant protein plays key role in Huntington’s disease

Back in 1993, researchers had discovered that Huntington’s disease is typically caused by a single mutated gene, known as HTT.

8 Mar 2021

Promising drug targets identified for aggressive forms of cancers

Scientists have largely been producing transcriptomic data in an attempt to find clues about modified cellular pathways that may be fueling cancer behavior.

5 Mar 2021

Mutant peptides derived from SARS-CoV-2 hamper activation of CD8+ killer T cells

A deep sequencing study of 747 SARS-CoV-2 virus isolates has revealed mutant peptides derived from the virus that cannot effectively bind to critical proteins on the surface of infected cells and, in turn, hamper activation of CD8+ killer T cells that recognize and destroy these infected cells.

5 Mar 2021

Three new COVID-19 variants can evade antibodies that act against original virus

New research at Washington University School of Medicine in St. Louis indicates that three new, fast-spreading variants of the virus that cause COVID-19 can evade antibodies that work against the original form of the virus that sparked the pandemic.

5 Mar 2021

Engineered safety switch reduces CAR-T immunotherapy-related side effects

UNC Lineberger Comprehensive Cancer Center researchers have successfully used an experimental safety switch, incorporated as part of a chimeric antigen receptor T-cell (CAR-T) therapy, a type of immunotherapy, to reduce the severity of treatment side effects that sometimes occur.

5 Mar 2021

Vegan diet leads to poorer bone health, shows study

The vegan diet is on-trend. How this type of diet affects health is the subject of scientific studies. In a new study from the German Federal Institute for Risk Assessment (BfR), the bone health of 36 vegans, as well as 36 people following a mixed-food diet, was determined with an ultrasound measurement of the heel bone.

5 Mar 2021