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Discovery of RNA Brake Offers Insights into Neurodevelopmental Disorders

When a gene produces too much protein, it can have devastating consequences on brain development and function.

24 Oct 2024

Structural Insights into Bacteriophages Open Doors for New Therapeutics

The viruses that infect bacteria are the most abundant biological entities on the planet. For example, a recent simple study of 92 showerheads and 36 toothbrushes from American bathrooms found more than 600 types of bacterial viruses, commonly called bacteriophages or phages.

23 Oct 2024

Unraveling the Mechanics Behind Transcription-Dependent Motions of Single Genes

A group of researchers has found unexpected links between genome packing, gene activity, and genome-wide motions, exposing features of the genome's structure that have a direct impact on gene expression and regulation.

23 Oct 2024

Unraveling the Genetic Blueprint of the Deep Brain

Researchers have discovered 254 genetic variations that influence important “deep brain” structures, such as those that govern memory, motor skills, addictive behaviors, and more, in one of the biggest-ever investigations of DNA and brain volume.

22 Oct 2024

Study Identifies Novel Chromatin Configuration in Turtle Genomes

Researchers from UAB and Iowa State University have produced the first-ever genome assemblies of two hidden-neck turtle species.

22 Oct 2024

Genetic Study Offers Hope for the Endangered Oriental Stork

A new genomic study of the endangered Oriental Stork reveals that the population's genetic health is still surprisingly strong, with high genetic diversity and low levels of inbreeding.

22 Oct 2024

Mapping Auxiliary Metabolic Genes in Ocean Viruses

The microbes that cycle nutrients in the ocean don't do the work on their own – the viruses that infect them also influence the process.

21 Oct 2024

Whole Genome Sequencing Reveals New Insights into Providencia rustigianii

Salmonella and E. coli are well-known bacteria that cause food poisoning, but less understood are species of Providencia, another causative agent of serious symptoms.

18 Oct 2024

Disinfectants Foster the Growth of Novel Microbial Strains in Urban Settings

A recent study in the journal Microbiome has uncovered new strains of microbes that have evolved to utilize the scarce resources found in cities, revealing that daily habits are altering the composition of microorganisms in indoor environments.

18 Oct 2024

Research Advances Understanding of Gene Expression Mechanisms

During embryonic development, cells start out as pluripotent, or have the potential to become many different cell types through differentiation.

17 Oct 2024

Genetic Study Reveals Vulnerability of Bonobos

Bonobos, endangered great apes that are among our closest relatives, might be more vulnerable than previously understood, finds a genetics study led by a UCL researcher that reveals three distinct populations.

17 Oct 2024

Study Unlocks Mechanisms Behind Nucleosome Arrays Using Signal Theory and Machine Learning

Findings show that machine learning can accurately predict nucleosome positions, emphasizing the relationship between nucleosome architecture and gene activity.

17 Oct 2024

Unveiling the Potential of YY1 in Blood Cell Development and Therapy

Common lymphoid progenitors, pre-pro-B cells, pro-B cells, pre-B cells, immature B cells, and finally more mature and specialized B cells are the stages in which B cells, white blood cells that produce antibodies, develop.

17 Oct 2024

Transposable Elements Drive a Critical Transition in Early Embryogenesis

Researchers at Sinai Health have discovered that DNA elements known as transposons, which may travel throughout the genome, control a crucial stage in early human development instead of human genes.

16 Oct 2024

Scientists Identify Drug-Binding Site on FOXA1

Forkhead box protein 1 (FOXA1) is a difficult-to-target protein that is frequently involved in hormone-driven malignancies, such as those of the breast and prostate.

16 Oct 2024

Next-Generation Sequencer Enhances Genetic Research at UT Arlington

The North Texas Genome Center (NTGC) at UT Arlington is getting an upgrade in the form of a next-generation genetic sequencer that will allow researchers to study genetic links between health and disease at a large scale.

16 Oct 2024

Transposable Elements Are Key to Normal Progression of Embryonic Cells

A critical transition in early human development is regulated not by our own genes, but by DNA elements called transposons that can move around the genome, Sinai Health researchers have found.

16 Oct 2024

High Potency Cannabis Leaves Unique DNA Signature, Study Shows

Published in Molecular Psychiatry, this is the first study to suggest that the use of high potency cannabis leaves a distinct mark on DNA, providing valuable insights into the biological impact of cannabis use.

16 Oct 2024

Melanin May Act as a "Drug Sponge," Influencing Medication Effectiveness

Skin pigmentation may act as a "sponge" for some medications, potentially influencing the speed with which active drugs reach their intended targets, a pair of scientists report in a perspective article published in the journal Human Genomics.

15 Oct 2024

New Discovery Reveals How MX Protein Traps HIV and Herpes Viruses

A group of researchers led by Xavier Saelens and Sven Eyckerman at the VIB-UGent Center for Medical Biotechnology discovered how a protein linked to the human immune system wards off HIV-1 and herpes simplex virus-1 by assembling structures in the cell that lure in these viruses and then trap them or even take them apart.

11 Oct 2024