CRISPR News and Research

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In the late 1980s and mid-1990s, genomes of diverse lineages of bacteria and archaea (the latter representing a domain of single-celled prokaryotic microorganisms) revealed clusters of regularly interspaced short palindromic repeats, known today under the abbreviation CRISPR. Later it was found that these repeat sequences (previously considered disparate) share a common set of features.

New Method Derives Red Blood Cell-Like Cells From Canine iPSCs

Blood transfusions are crucial in human and veterinary medicine, yet human blood reserves are in constant need of donors while blood bank systems in veterinary care are nearly non-existent.

20 Jul 2026

AI Breakthrough Generates Novel Synthetic RNA-Guided Nucleases

Artificial intelligence (AI)-designed proteins can now expand the CRISPR toolbox beyond what evolution has produced.

17 Jul 2026

Novel T Cell Immune Path Targets Aggressive Acute Myeloid Leukemia

Researchers at The University of Texas MD Anderson Cancer Center have discovered a new way in which T cells attack acute myeloid leukemia (AML) cells, which may help explain why AML is particularly sensitive to immune-based treatments and could guide the development of future cancer immunotherapies.

16 Jul 2026

Intermicrobial Antagonism Controls Essential Bacteria Populations in Human Guts

Mougous, John F. Enders Professor of Microbial Pathogenesis at Yale School of Medicine (YSM), studies bacterial warfare, or how different microbes defend their ecological niches against other species.

14 Jul 2026

New CRISPR Atlas Details How Every Gene Influences Stem Cells

A team led by bioengineers at the University of California San Diego has developed a genome-scale reference map that details how individual genes control the functions and identities of human stem cells.

14 Jul 2026

Next-Generation Biosensing Shows How Bacteriophages Revolutionize Bacterial Disease Detection

Pathogenic bacteria remain a persistent threat to public health, food supplies, and water systems, particularly as antimicrobial resistance makes infections increasingly difficult to treat.

11 Jul 2026

Nature Study Reveals Hidden Genes Driving Hard-to-Treat Tumors

Researchers have solved a long-standing mystery of how abnormal chromosomes drive cancer, identifying 81 new genes involved in aggressive breast cancer.

9 Jul 2026

New Evolutionary Theory Uses Bacteriophages to Overcome Antimicrobial Resistant Infections

A new perspective article in Biocontaminant proposes a three-part evolutionary framework for using bacteriophages to better control antimicrobial resistance.

3 Jul 2026

Stem T Cells Replenish the Immune System During Chronic Infections and Diseases

T cells are an elite fighting force of the immune system, seeking out and destroying diseased cells. But in a prolonged campaign against a chronic condition - like a viral infection, or cancer - the body needs a steady supply of these killer troops. Where and how these killer troops are generated has been a mystery.

2 Jul 2026

Single Nucleus RNA Sequencing Decodes Tomato Plant Early Stage Development

Seedling emergence is one of the most vulnerable stages in plant life. In darkness, seedlings undergo skotomorphogenesis, forming elongated hypocotyls and curved apical hooks that protect the shoot tip as it pushes through soil.

29 Jun 2026

Targeting Iron Metabolism Offers a New Strategy to Kill Cancer Cells

Researchers from the University of Michigan Health Rogel Cancer Center have discovered a key metabolic pathway that allows colorectal cancer cells to accumulate large quantities of iron. Blocking that pathway reduced iron levels and caused the cancer cells to die.

22 Jun 2026

New Delivery Tool Framework Replaces Time Consuming Cell Regeneration Bottlenecks

Clustered regularly interspaced short palindromic repeat (CRISPR)-Cas technologies have transformed plant biotechnology, but getting editing machinery into plant cells remains a major bottleneck.

16 Jun 2026

Salk Researchers Uncover Specialized Plant Protein for DNA Repair

Similar to the way DNA damage can contribute to human diseases like cancer, it can also disrupt growth, development, and survival in plants.

9 Jun 2026

Biologists Capture Snapshot of Evolutionary Transition in Y Chromosome Gene

The study, published in Volume 153, Issue 9 of the journal Development on May 14, 2026, by The Company of Biologists, is the first to precisely map endogenous UTY occupancy across the human genome and demonstrate that UTY remains functionally involved in transcriptional regulation during early human development.

8 Jun 2026

Antibody-Directed Xenophagy Pathway Blocks Intracellular Infections From Spreading

Scientists have revealed the process by which cells can internally digest bacteria and viruses.

5 Jun 2026

New Gene-Editing Strategy Ensures Quality Control in Stem Cell Therapies

A team of researchers led by Luigi Naldini at the San Raffaele Telethon Institute for Gene Therapy (SR-Tiget) has developed a new strategy to significantly improve the precision and safety of CRISPR-Cas9 gene editing.

3 Jun 2026

Cornell Researchers Develop Safer CRISPR Technique Using DNA Nicks

Researchers at Cornell University have developed a safer and more precise way to study how genes function in living tissues by refining a recently developed CRISPR-based genetic technique in fruit flies, enabling researchers to better study how genes contribute to development and disease.

28 May 2026

Ovarian Cancer Fluid Helps Tumors Evade Cell Death

Ascites in ovarian cancer rewires tumor metabolism, protecting cells from ferroptosis and promoting metastasis, revealing potential therapeutic targets.

27 May 2026

Genomewide CRISPR Screen Reveals Unexpected Structural Protein Link Behind Chronic Colon Inflammation

Since a landmark 2009 study, researchers have known that a common gut bacterium, Bacteroides fragilis, drives colon tumor formation, potentially leading to colorectal cancer, by secreting a toxin that damages the lining of the colon. But until now, the exact mechanism the toxin uses to latch onto those cells remained a mystery.

25 May 2026

Synthetic Biology and Artificial Intelligence Transform the Discovery of Mysterious Orphan Receptors

A new review highlights how synthetic biology, AI, and spatial omics could transform ligand-receptor discovery from one-by-one searches into network-level mapping

23 May 2026