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New Computational Tools Improve Gene Function Determination Within Fungal Organisms

While RNA sequencing (RNA-seq) has become a standard tool for profiling which genes are active in an organism, determining the actual biological functions of those genes in fungi remains a significant technical challenge. Most existing software tools are designed to cover a broad range of species, often lacking the specificity required for the unique genetic landscape of fungi.

31 Mar 2026

New Genetic Pathways and Compounds Identified to Prevent Cone Degeneration

Scientists led by Botond Roska at the Institute of Molecular and Clinical Ophthalmology Basel (IOB) and collaborators have identified genetic pathways and compounds capable of protecting cone photoreceptors from the degeneration that underlies conditions like age-related macular degeneration.

30 Mar 2026

Identifying the Cellular Origin of MS-Related Neuroinflammation

Signals from the gut have been linked to autoimmune inflammation, but fundamental cellular processes remain poorly understood.

30 Mar 2026

New Technology Enables Whole-Body Analysis of Gene Expression

Understanding gene expression within the body has been a boon for 21st century biology and therapeutics, but most discoveries that use these technologies only focus on one organ or one small area of tissue.

30 Mar 2026

New Neural Organoid System Enables Scalable Brain Network Studies

Neural organoids have been heralded as having huge potential for advancing our knowledge of the brain in several fields.

30 Mar 2026

Genetic Study Reveals Insecticide Resistance in Malaria Vector Mosquitoes

Anopheles darlingi mosquitoes-a major vector of malaria in South America-are evolving in response to insecticides, which may make them harder to kill and malaria more difficult to control, according to a new study led by Harvard T.H. Chan School of Public Health.

28 Mar 2026

Global Experiment Tracks Real-Time Plant Evolution in Changing Climates

For decades, ever since biologists recognized the potential environmental harms from climate change, they have worried that plants will not be able to evolve fast enough to adapt to a rapidly warming planet.

28 Mar 2026

Genome-Wide Screen Reveals Drivers of Ciprofloxacin Tolerance Mechanisms

Persisters are a bacterial subpopulation that exhibits tolerance to antibiotics and plays a critical role in chronic and recurrent infections.

28 Mar 2026

Fusion Protein Rewires Brain Development to Trigger Pediatric Cancer

A team of researchers at Baylor College of Medicine, St. Jude Children's Research Hospital, Texas Children's Hospital and collaborating institutions reveal in the journal Nature a novel mechanism that drives the development of pediatric supratentorial ependymoma (EPN), the third most common pediatric brain tumor.

28 Mar 2026

Study Reveals How STING Protein Migrates to Trigger Immune Responses

UT Southwestern Medical Center researchers have identified how the quintessential immune protein known as stimulator of interferon genes (STING) migrates from one cellular organelle to another, a necessary step in its activation.

27 Mar 2026

Microtubules Act as Active Regulators of Key Cellular Enzymatic Reactions

Microtubules, the dynamic filaments that form the cell's internal scaffolding, have long been viewed as mere passive structural supports. But a new study reveals they play a far more active signaling role.

27 Mar 2026

Genetic Analysis Reveals Why Haploid Fish Embryos Fail to Survive

Naturally occurring haploids are predominantly documented in plants; the first report dates to 1923, when haploid individuals were identified in the Jimson Weed.

27 Mar 2026

The New Microchip Electrophoresis System MultiNA II MCE-301 - High Sensitivity Detection, Improved Analysis Function and Operability

Shimadzu has recently released the MultiNA II MCE-301 microchip electrophoresis system.

From Shimadzu Europa GmbH 27 Mar 2026

Newly Discovered CRISPR System Activates Genes Without Cutting DNA

In back-to-back studies published in Nature, researchers from Purdue University and Columbia University report a naturally evolved gene-editing system that can activate genes, offering an advantage over existing CRISPR gene-editing systems that merely find and cut DNA.

26 Mar 2026

New Skin Atlas Reveals Cellular Diversity Across Body Sites

Mount Sinai researchers have published the first organ-wide human skin spatial atlas from across the body.

26 Mar 2026

Genetic Study Maps E. coli Capsules Behind Severe Infections

The first large-scale genetic study of E. coli's protective armor has identified the five capsule types that are responsible for 70 per cent of all multidrug-resistant bloodstream infections in Europe.

26 Mar 2026

Scientists Map Gene Sharing Networks in Wastewater Treatment Biofilms

Wastewater treatment systems are hotspots for mobile genetic elements proliferation and exchange, where dense biofilms create ideal conditions for horizontal gene transfer.

24 Mar 2026

Study Highlights Hidden Protist Diversity Through Single-Cell Genomics

Researchers from the Earlham Institute, in collaboration with The Department of Biology at the University of Oxford, discovered three previously unrecognised lineages of the protist Bodo, each with its own bacterial endosymbiont (a symbiotic organism living within the body of its host).

23 Mar 2026

New Mechanism Links Mitochondria Dysfunction to T Cell Exhaustion

The immune system's killer T cells do a commendable job of detecting and destroying cancer cells. But the harsh environment at the heart of tumors often saps them of their vitality, pushing them into a state of permanent lassitude called "terminal exhaustion."

23 Mar 2026

New Enzyme Atlas Rewrites Decades of Biology Research

WEHI researchers have led a major global effort to create the first authoritative atlas for a class of enzymes that regulate almost every cellular process in the human body.

From Walter and Eliza Hall Institute of Medical Research (WEHI) 23 Mar 2026