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Natural Molecular Brake Prevents Uncontrolled DNA Replication in Cells

For almost 60 years, scientists have tried to understand why DNA doesn't replicate wildly and uncontrollably every time a cell divides – which they need to do constantly. Without this process, we would die.

29 Jan 2026

New Epigenetic Catalog Helps Explain Individual Differences in Immune Responses

The COVID-19 pandemic gave us tremendous perspective on how wildly symptoms and outcomes can vary between patients experiencing the same infection.

28 Jan 2026

Expanding CRISPR to Tackle Incurable Skin Diseases

Gene-editing techniques such as CRISPR have enabled new treatments for previously incurable diseases. Researchers at the University of British Columbia are now expanding those capabilities to include the skin for the first time.

28 Jan 2026

Melbourne Scientists Use AI to Tame CRISPR

Last year a ten-month old baby in the US was the first person in the world to have their rare genetic disease effectively cured through the use of CRISPR gene editing technology.

27 Jan 2026

Novel Epigenetic Regulator Enhances Downy Mildew Resistance in Brassica rapa

Downy mildew is a major constraint on Brassica crop production worldwide, especially during early developmental stages when plants are highly vulnerable to infection.

27 Jan 2026

Prehistoric Genome Pushes Back Origins of Treponemal Diseases in the Americas

Scientists have recovered a genome of Treponema pallidum – the bacterium whose subspecies today are responsible for four treponemal diseases, including syphilis – from 5,500-year-old human remains in Sabana de Bogotá, Colombia.

24 Jan 2026

Single Enzyme Enables Low-Cost Synthesis of All RNA Nucleotides

A single enzyme that can generate all four nucleotide triphosphates, the building blocks of ribonucleic acid (RNA), was identified by researchers at the Institute of Science Tokyo.

24 Jan 2026

Large African Ancestry Genetic Study Reveals Shared Biology Of Schizophrenia

A team of researchers led by scientists from the Icahn School of Medicine at Mount Sinai, SUNY Downstate Health Sciences University, and the Department of Veterans Affairs has conducted the largest and most comprehensive genome-wide association study (GWAS) to date of schizophrenia in individuals of African ancestry.

24 Jan 2026

Maternal And Fetal Cell Exchange Shapes Health Across Multiple Generations

During pregnancy, maternal and fetal cells migrate back and forth across the placenta, with fetal cells entering the mother's bloodstream and tissues.

24 Jan 2026

Why the Brain Never Stops Trying to Replace Myelin-Producing Cells

Researchers from Johns Hopkins Medicine, utilizing mouse models, reveal that oligodendrocyte precursor cells differentiate at a consistent, extensive rate throughout adulthood.

23 Jan 2026

Coordinated Gene Regulation Drives Saponin Production

Triterpenoid saponins are widely valued for their diverse pharmacological activities and also play important defensive roles in plants.

22 Jan 2026

Freeze Thaw Cycles Reveal How Lipid Membranes Shape Early Protocell Evolution

Modern cells are complex chemical entities with cytoskeletons, finely regulated internal and external molecules, and genetic material that determines nearly every aspect of their functioning.

21 Jan 2026

Bacteria Use One Simple Strategy to Navigate Complex Worlds

Just like every other creature, bacteria have evolved creative ways of getting around. Sometimes this is easy, like swimming in open water, but navigating more confined spaces poses different challenges.

19 Jan 2026

Decoding the Molecular Logic of Histamine Signaling in the Brain

Many people are familiar with histamine, a biological molecule, that serves as a key driver of allergic reactions and other immune responses.

19 Jan 2026

Replacing Large Mouse Gene Regions with Human DNA

Humanized mouse models are essential for investigating human gene function; however, the complete replacement of mouse genes with entire human sequences has posed significant technical challenges.

19 Jan 2026

New Pangenomic Approach Enables Unprecedented Scaling for Genetic Data

Researchers at the University of California have created a novel data structure and compression method that allows pangenomics to process genetic information at previously unattainable scales.

14 Jan 2026

New Technique Measures How Effectively Antibiotics Kill Bacteria

Drugs that act against bacteria are mainly assessed based on how well they inhibit bacterial growth under laboratory conditions.

12 Jan 2026

New Algorithms Automate Counting of Sister Chromatid Exchanges in Microscope Images

Researchers from Tokyo Metropolitan University have developed a suite of algorithms to automate the counting of sister chromatid exchanges (SCE) in chromosomes under the microscope. Conventional analysis requires trained personnel and time, with variability between different people.

12 Jan 2026

Immune Cell Atlas of Multiple Myeloma Could Guide Future Treatment Strategies

Scientists at the Icahn School of Medicine at Mount Sinai, in partnership with the Multiple Myeloma Research Foundation (MMRF) and in collaboration with leading institutions across the country, have helped generate the largest single-cell immune cell atlas of the bone marrow in patients with multiple myeloma, a blood cancer that, while treatable, remains incurable.

12 Jan 2026

Population-Specific Proteomic Analysis Advances Precision Medicine for Type 2 Diabetes

Researchers have conducted the most comprehensive analysis to date linking plasma proteins to genetic variation in individuals from continental Africa.

9 Jan 2026