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Epigenetic DNA Methylation Clocks Track Gradual Cellular Rejuvenation Across Fifty Days

Researchers from the University Hospital of Bonn and the University of Bonn have succeeded in dramatically rejuvenating human cells in a test tube. To do so, they directly reprogrammed red blood cell precursors into stem cells from which neurons can be derived. During this process, the molecular clocks that indicate a cell's age were reset.

10 Oct 2026

How a Single Transcription Factor Keeps Chinese Cabbage From Bolting Too Early

Bolting time is a critical agronomic trait in Brassica campestris. Once the plant shifts from producing edible leaves to flowering, leaf production ceases, leading to rapid deterioration of yield and quality.

9 Oct 2026

Ancient Peptide Signals Shape Apple Root Regeneration

Apple production depends heavily on grafting, making rootstock traits central to water and nutrient uptake, stress resilience, and orchard performance.

9 Oct 2026

Granular Genetic Risk Prediction Enables Early Detection of Hearing Loss

The team, composed of investigators from clinical audiology, ear surgery and general otolaryngology, was led by co-first author Andie DeFreese, AuD, a clinical audiologist and PhD candidate in the Department of Hearing and Speech Sciences at Vanderbilt Health.

9 Oct 2026

Transposable Element Methylation Instability Impairs Overall Genomic Regulation in Large Breeds

Why do large dogs tend to live shorter lives than their smaller counterparts? According to a new study of nearly 900 dogs, the answer may be written into their epigenome. The findings reveal that larger and male dogs undergo accelerated molecular aging, with pronounced DNA methylation (DNAm) on the X chromosome and at transposable elements (TEs).

9 Oct 2026

Retrotransposon Reactivation Suggests Reverse Transcriptase Inhibitors Lower Cancer Risk

A tumor suppressor gene known as p53 is mutated in more than half of all cancers, but how it acts to prevent cancer formation is largely unknown.

9 Oct 2026

Prime Editing Generates Genomic Ticker Tapes Tracing Millions of Developing Cells

Growing inside each of us is a cellular family tree.

9 Oct 2026

Genetic Analysis of Spotted Bats Traces Evolution Across Time

Understanding changes in North American bat populations is critical to measuring risk of extinction from emerging threats such as habitat loss, climate change, white nose syndrome and other disturbances.

8 Oct 2026

Ancient Gut Microbes Traveled Globally With Prehistoric Human Ancestors

As waves of humans left Africa tens of thousands of years ago, eventually populating the entire planet, they were joined on their world-conquering ride by the trillions of microorganisms that compose the gut microbiome.

8 Oct 2026

Rare Metabolic Gene Unexpectedly Tied to Inherited Blindness

Scientists at the Greenwood Genetic Center (GGC) spearheaded the identification of an unforeseen link between genetic blindness and a gene associated with a rare metabolic disorder.

8 Oct 2026

Stem Cell Models Demonstrate Precise Cellular Nibbling of Pathological Fibrils

Researchers at the University of Oxford have uncovered a previously unrecognized protective role for microglia, the brain's resident immune cells, in Parkinson's disease.

8 Oct 2026

Aldabra Giant Tortoise Genome Provides Evolutionary Blueprint for Cellular Resilience

Researchers studying a giant tortoise named Jonathan say it's not just good genes, but lack of genetic wear and tear that have kept him going for nearly two centuries.

8 Oct 2026

Mitochondrial Genome Dynamics Influence Intrinsic Tumor Aggressiveness

Mitochondria are small organelles within cells that play a central role in vital cellular processes, especially energy production.

8 Oct 2026

Integrated Multi-Omics Maps Metabolic Shift During Seed Development Stages

Canavalia gladiata, commonly known as sword bean, is a leguminous crop with high seed protein content (26%–30%) and oil rich in unsaturated fatty acids. Despite its nutritional promise, the species has remained underutilized, largely because a complete genome and the genetic basis of its nutritional traits were lacking.

8 Oct 2026

Obligate Endosymbionts Synthesize Vital Amino Acids and Nutrients for Host Survival

Endosymbionts are widely distributed across various cell types in insects and are transmitted primarily vertically, while also spreading among different hosts through horizontal transmission. Functionally, they can be divided into obligate (primary) and facultative (secondary) endosymbionts.

8 Oct 2026

Ancient DNA Reveals Extinct Bovine Species in Southern Siberia

DNA analyses of ancient remains have revealed a previously unknown extinct bovine species that inhabited southern Siberia during and even before the last Ice Age.

6 Oct 2026

Deciphering Bacterial Antiviral Defenses Aids Design of Immune-Evading Phages

In the fight to find better treatments for bacterial infections, one rapidly evolving therapy is a group of viruses called bacteriophages (phages). Phages can attack and kill dangerous bacteria while leaving human cells unharmed and bypassing antibiotic resistance.

5 Oct 2026