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Tumor Bacteria Found to Drive Immunotherapy Resistance

Cleveland Clinic researchers have discovered that bacteria inside cancerous tumors may be key to understanding why immunotherapy works for some patients but not others.

5 Jan 2026

Scientists Develop Noise Controller to Tame Random Cell Behavior

Why does cancer sometimes recur after chemotherapy? Why do some bacteria survive antibiotic treatment? In many cases, the answer appears to lie not in genetic differences, but in biological noise - random fluctuations in molecular activity that occur even among genetically identical cells.

5 Jan 2026

New CHANGE-seq-BE Method Sharpens Safety Assessment of CRISPR Base Editors

Scientists and physicians can better assess precision genome editing technology using a new method made public today by St. Jude Children's Research Hospital.

5 Jan 2026

Mapping Two Millennia of Betaherpesvirus Evolution via Ancient Human Genomes

Researchers have successfully reconstructed the ancient genomes of Human betaherpesvirus 6A and 6B (HHV-6A/B) from human remains that are over two thousand years old.

5 Jan 2026

Base-Pair Resolution Benchmark Uncovers Structural Variation Complexity in Tomato Genomes

Structural variations (SVs), including insertions, deletions, inversions, and substitutions, can profoundly influence gene regulation and phenotype.

2 Jan 2026

Single-Donor Lung-on-Chip Enables Personalized TB Research

Researchers at the Francis Crick Institute and AlveoliX have developed the first human 'lung-on-chip' model using stem cells taken from only one person.

2 Jan 2026

Homer1 Gene Plays a Critical Role in Shaping Attention

Attention disorders such as ADHD involve a breakdown in our ability to separate signal from noise.

26 Dec 2025

Stem Cells Mimic Earliest Stages of Brain Development in a Dish

Researchers have made great strides to understand early signs of autism. Studies have found that certain factors like genetics, sleep deprivation, excess fluid in the brain-and brain size-can increase the risk of neurodevelopmental conditions, like autism.

26 Dec 2025

Antibiotic Resistance: A Global Crisis Threatening Modern Medicine's Future

Once a medical miracle, antibiotics are now losing their power. Across the world, common infections are becoming harder-and sometimes impossible-to treat. This new review paints a sobering picture of global antimicrobial resistance (AMR), tracing how bacteria and fungi are evolving faster than medicine can respond.

24 Dec 2025

Researchers Find Enzyme That Controls Fat Production, Offering New Drug Target

Obesity is a global epidemic and a major cause of morbidity and mortality because it increases the risk for comorbidities, including heart disease and fatty liver disease (MASLD). Rates of these disorders have risen as the world increasingly adopts energy-dense diets and sedentary lifestyles.

24 Dec 2025

Stem Cell Models Offer Insights Into Early Brain Development and Autism

24 Dec 2025

Genetic Factor "Fru" Influences Bees' Cooperative Food-Seeking Behavior

A team of biologists from Heinrich Heine University Düsseldorf (HHU), along with researchers from Bochum and Paris, has uncovered a genetic component underlying intricate social behaviors in bees.

24 Dec 2025

Mapping the Four Dimensional Organization of the Human Genome

A new study challenges what's long been assumed about genetic variants thought to always cause inherited blindness.

23 Dec 2025

Study Challenges Long-Held Assumptions About Mendelian Retinal Disorders

A new study challenges what's long been assumed about genetic variants thought to always cause inherited blindness.

23 Dec 2025

Calcium Signaling Suppresses Lignin Accumulation in Pear Stone Cells

Stone cells arise from lignified secondary cell walls and cause a gritty texture, reduced sweetness, and poor flavor in many pear cultivars.

23 Dec 2025

Protein MCL1 Emerges as a Central Regulator of Cancer Metabolism

The researchers have succeeded in tracing two classic hallmarks of cancer – the evasion of apoptosis (a form of programmed cell death) and the dysregulation of energy metabolism – back to a common molecular mechanism.

23 Dec 2025

Foreign RsMYB28 Allele Boosts Glucosinolate Accumulation in Rapeseed

These bioactive compounds, found primarily in Brassicaceae plants, play crucial roles in plant defense, contribute to distinctive food flavors, and have potential health benefits, including cancer prevention.

23 Dec 2025

Wasatch Biolabs Announces Co-Marketing Agreement with Agilent to Advance Native-Read Targeted Sequencing

Wasatch BioLabs (WBL), a leader in native, long-read sequencing and epigenomic analysis, today announced a co-marketing agreement with Agilent Technologies to support the adoption of its Direct Targeted Methylation Sequencing (dTMS) platform.

22 Dec 2025

Researchers Map Gene Activation in Lethal Fungal Outbreaks

Scientists have discovered a genetic process which could unlock new ways to treat mysterious and deadly fungal infection which has shut down multiple hospital intensive care units.

22 Dec 2025

New Rat Study Reveals How Genetic Traits Ripple Through Social Microbiomes

The gut microbiome - made up of trillions of microbes in the digestive tract - is vital for digestion and overall health. Diet and medication shape these microbial ecosystems, but the contribution of genetics has been more difficult to ascertain.

22 Dec 2025