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Zinc-Carrying Proteins Activate Proton Pump Inhibitors in Neutral Environments

Acid reducing medicines from the group of proton pump inhibitors (PPIs) are best-selling drugs that prevent and alleviate stomach problems.

22 Feb 2025

Understanding the World Beyond DNA and Genes

Curled up inside every single one of the trillions of cells in the human body is six feet of DNA, spooled tightly and carrying the genetic instructions that govern so much of who a person becomes.

17 Feb 2025

Gene Editing Breakthrough Creates CoQ10-Producing Rice Varieties

A team of Chinese scientists has used targeted gene editing to develop rice that produces coenzyme CoQ10 (CoQ10), a vital compound for human health.

17 Feb 2025

Intermittent Fasting Disrupts Development of Insulin-Producing Beta Cells in Young Mice

A recent study reveals that age plays a significant role in the outcomes of intermittent fasting. Researchers from Technical University of Munich (TUM), LMU Hospital Munich, and Helmholtz Munich discovered that chronic intermittent fasting disrupted the development of insulin-producing beta cells in young mice.

17 Feb 2025

New AI Pipeline Revolutionizes Molecular Target Identification

When researchers create new molecules whether for agricultural applications, species management, or life-saving medications it is essential to identify their specific targets.

17 Feb 2025

How Bacteriophages Build a Protein-Based Nucleus to Outsmart Bacteria

Jumbo phages utilize a complex protein import system, with Imp1 as a key gatekeeper, to transport proteins into their protective nucleus-like compartment.

14 Feb 2025

Research Sheds Light on How Obesity Affects Gene Expression in Fat Cells

As many as 40% of Americans are obese, putting them at an increased risk for high blood pressure, diabetes, stroke, heart disease and certain cancers, according to the CDC.

11 Feb 2025

Protecting Plant Cells from Damage with ATG8ylation

Plants droop and shed their leaves when parched, but with a splash of water, their stems regain strength and their leaves unfurl.

10 Feb 2025

Scientists Decode ApoB100 Structure for Targeted Heart Disease Treatments

Low-density lipoproteins (LDL) - commonly known as bad cholesterol - have long been on scientists' radar as a major contributor to heart disease.

4 Feb 2025

Omega-3 Slows Aging at the DNA Level, Vitamin D and Exercise Boost the Effect

A clinical trial found that omega-3 supplementation modestly slowed biological aging, with additional benefits when combined with vitamin D and exercise.

4 Feb 2025

Gut Microbes May Explain Link Between Sugar-Sweetened Beverages and Diabetes

It is well known that consuming sugary drinks increases the risk of diabetes, but the mechanism behind this relationship is unclear.

3 Feb 2025

New Protein Structures Could Lead to Better Treatments for Transthyretin Amyloidosis

The tiny protein known as transthyretin can cause big problems in the body when it misfolds after secretion.

29 Jan 2025

Unique Genetic Signature Predicts Bacteria's Potential to Develop Antibiotic Resistance

Antibiotic resistance is a global public health crisis responsible for more than a million deaths annually.

29 Jan 2025

New Consensus Paper Advances Nomenclature for Mitochondria Transfer and Transplantation

Most animal, plant and fungal cells contain organelles called mitochondria. These descendants of a primordial bacterial endosymbiont still preserve distinct genes and are known for their ability to create ATP as chemical energy.

28 Jan 2025

Fast and Precise Protein Labeling in Intact Tissues with MIT Technology

A new technology developed at MIT enables scientists to label proteins across millions of individual cells in fully intact 3D tissues with unprecedented speed, uniformity, and versatility.

27 Jan 2025

Digoxin Weakens Cancer’s Spread by Targeting Cell Clusters

Some tumor types spread throughout the body and develop metastases instead of staying at their original location.

27 Jan 2025

New Research Sheds Light on Y Chromosome’s Role in Male Infertility

Researchers at the Crick have uncovered which genes on the Y chromosome regulate the development of sperm and impact fertility in male mice.

24 Jan 2025

New Method for Engineering GPCRs Opens Pathways for Advanced Drug Development

Proteins are life's engines, powering processes like muscle movement, vision, and chemical reactions.

24 Jan 2025

Microgravity Unlocks Secrets to Heart Cell Survival for Earth-Based Therapies

A team of researchers led by Emory's Chunhui Xu recently found that heart muscle cells can grow -and survive in the microgravity environment of space.

22 Jan 2025

Researchers Develop Method to Visualize Nanocarriers at Single-Cell Level

How can we ensure that life-saving drugs or genetic therapies reach their intended target cells without causing harmful side effects? Researchers at Helmholtz Munich, Ludwig-Maximilians-Universität (LMU) and Technical University Munich (TUM) have taken an important step to answer this question.

16 Jan 2025