Immune System News and Research

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A Next-Gen CRISPR Tool Just Dropped

Over the past 15 years, developments in the gene-editing technique known as CRISPR-Cas9 have produced significant new understandings of the functions that particular genes play in a variety of disorders.

21 Mar 2025

RNA-Based Active Agents Successfully Shield Plants from Cucumber Mosaic Virus

New RNA-based active agents reliably protect plants against the Cucumber mosaic virus (CMV), the most common virus in agriculture and horticulture. They were developed by researchers at the Martin Luther University Halle-Wittenberg (MLU).

20 Mar 2025

Lobate Shape of Lymphatic Cells Provides Stability Against Fluid Shifts

The cells that make up the walls of the finest of all lymphatic vessels have a lobate, oak leaf-like shape that makes them particularly resilient to changes in fluid volume.

20 Mar 2025

New Insights into How B Cells Strategically Clone High-Affinity Antibodies

A vaccine's ability to generate long-lasting, high-affinity antibodies hinges on a delicate balance. Upon exposure to a vaccine or pathogen, B cells scramble to refine their defenses, rapidly mutating in hopes of generating the most effective antibodies.

20 Mar 2025

Bioengineering a Luminous Biosensor for Aberrant DNA Detection

Cells contain a DNA sensor called cGAS, which alerts the immune system to viral and bacterial infections, cell death, and cancer-related transformations.

20 Mar 2025

Advanced Imaging Deciphers B Cell Dynamics in Lymph Nodes

Germinal centers are machines of rapid evolution. Germinal centers are tiny clusters in the lymph nodes that refine antibodies through proliferation and mutation to create high-affinity B cells that are suited to control various infections.

20 Mar 2025

AI Revolutionizes Cell Analysis for Personalized Cancer Treatment

A groundbreaking artificial intelligence (AI)-driven neural network has been developed to swiftly analyze and interpret millions of cells from patient samples, enabling predictions of molecular alterations within tissues.

19 Mar 2025

New Insights into RNA Editing Mechanisms for Autoimmune and Cancer Therapies

A research team led by Yang Gao from Rice University has made significant strides in understanding the molecular mechanisms of ADAR1, a protein that modulates ribonucleic acid (RNA) induced immune responses.

18 Mar 2025

Mitochondria Found to Control DNA Repair Protein and Delay Inflammaging

In humans and other multicellular organisms, cells multiply. This defining feature allows embryos to grow into adulthood, and enables the healing of the many bumps, bruises and scrapes along the way.

14 Mar 2025

Bispecific antibodies for SARS-CoV-2 variant neutralization

Bispecific antibodies targeting multiple SARS-CoV-2 sites offer enhanced neutralization against emerging variants, advancing COVID-19 treatment strategies.

14 Mar 2025

Combination of Viral Antibodies and Genetic Risk Factors Linked to Increased MS Risk

In multiple sclerosis (MS), antibodies to the common Epstein-Barr virus can accidentally attack a protein in the brain and spinal cord. New research shows that the combination of certain viral antibodies and genetic risk factors can be linked to a greatly increased risk of MS.

12 Mar 2025

$30 Million Grant Supports AI-Powered Antibody Therapy Development

An ambitious project led by Vanderbilt University Medical Center investigators aims to use artificial intelligence technologies to generate antibody therapies against any antigen target of interest.

10 Mar 2025

Cellular Changes as Lung Damage Worsens During COVID-19 Revealed

Changes in the cellular response during lung damage caused by SARS-CoV-2 – the virus behind COVID-19 – have been uncovered.

10 Mar 2025

Macrophages Use Bacterial Debris To Fine-Tune Immune Responses

Findings reveal macrophages' role in immune modulation through bacterial metabolites, paving the way for improved therapies for infections and inflammation.

6 Mar 2025

Unveiling the Role of NUDIX Hydrolase in Fungal Infection

Researchers from The Australian National University (ANU), in partnership with scientists from Germany and the United States, have identified a potent “weapon” employed by numerous pathogenic fungi to infect staple food crops like rice and corn. This discovery may lead to novel approaches for enhancing global food security.

28 Feb 2025