Molecular Biology News and Research

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Molecular biology is the study of biology at a molecular level. The field overlaps with other areas of biology and chemistry, particularly genetics and biochemistry. Molecular biology chiefly concerns itself with understanding the interactions between the various systems of a cell, including the interactions between DNA, RNA and protein biosynthesis as well as learning how these interactions are regulated.

Novel Chromosome Identification System Overcomes Longstanding Bottleneck in Alfalfa Cytogenetics

Karyotype analysis is fundamental to understanding genetic makeup, diversity, and adaptation in plants. Yet, distinguishing individual chromosomes remains challenging in species with small, uniform chromosomes and complex polyploid genomes such as alfalfa.

22 Sep 2025

PANoptosis Could Revolutionize Liver Cancer Diagnostics and Treatment

Liver cancer, particularly hepatocellular carcinoma (HCC), remains one of the deadliest cancers, driven by high recurrence and resistance to therapy.

22 Sep 2025

Carbon Starvation Drives Metabolic and Epigenetic Reprogramming in Grapevine Cells

Plants rely on sugars not only as energy sources but also as regulators of cellular activities. Carbon starvation disrupts central metabolism, impairs growth, and forces cells to recycle stored resources.

18 Sep 2025

Tracing Evolutionary Roots of the Genetic Code

Genes are the building blocks of life, and the genetic code provides the instructions for the complex processes that make organisms function.

17 Sep 2025

Microarray Profiling Identifies LINC00974 as a Sensitive Marker for Breast Cancer Risk

In the post-genomic era, long non-coding RNAs (lncRNAs) have emerged as critical regulators in various cancers and hold potential as minimally invasive diagnostic biomarkers.

16 Sep 2025

A Molecular Magnifying Glass for Tracking Protein Misfolding in Living Cells

A novel strategy developed at Rice University allows scientists to zoom in on tiny segments of proteins inside living cells, revealing localized environmental changes that could indicate the earliest stages of diseases such as Alzheimer's, Parkinson's and cancer.

15 Sep 2025

Blocking SUMO2 Protein may be a Winning Strategy Against Synovial Sarcoma

In the sport of sumo, a bout most commonly ends when one competitor is pushed or thrown outside of a ring of straw bales partially buried in clay.

8 Sep 2025

Discovery of De Novo Genes Sheds Light on Peach Evolution and Traits

The emergence of new genes is a central driver of evolutionary innovation. While mechanisms such as duplication and horizontal gene transfer have been widely studied, de novo gene birth represents a unique pathway where functional genes arise from noncoding DNA.

8 Sep 2025

Intestinal Cells Pull Rather Than Push to Remove Weaker Neighbors

Cells on the inner surface of the intestine are replaced every few days. But, how does this work? It was always assumed that cells leave the intestinal surface because excess cells are pushed out. In a recent publication in the journal Science, researchers of the Hubrecht Institute and AMOLF show that this is not correct.

4 Sep 2025

Novel Fluorescent Reporter Technology Enables Real-Time Visualization of Apoptosis Inside Cells

Cells in our body are programmed to die after a certain period of time-a natural process known as apoptosis or "cell suicide."

4 Sep 2025

RNAConnect® Announces Commercial Launch of UltraMarathonRT® cDNA Synthesis and Amplification Kit for Enhanced Short-Read RNA Sequencing

RNAConnect, a leader in next-generation molecular biology tools, today announced the commercial launch of the UltraMarathonRT cDNA Synthesis and Amplification Kit, designed to elevate short-read RNA sequencing workflows.

3 Sep 2025

Genetic Study Reveals Independent Origins of Eye Loss in Cavefish

Small, colorless, and blind, amblyopsid cavefishes inhabit subterranean waters throughout the eastern United States.

28 Aug 2025

New "DNA Organizer" Found to Be Essential for Sperm Stem Cell Development

A research team at Kyoto University has discovered STAG3-cohesin, a new mitotic cohesin complex that helps establish the unique DNA architecture of spermaotogonial stem cells (SSCs), the stem cells that give rise to sperm.

27 Aug 2025

New Research Explains How Alcohol Inhibits Gut Health

Alcohol-associated liver disease (ALD) is a leading cause of liver transplantation and mortality globally, and its effect is only increasing.

27 Aug 2025

Breakthrough Technique Enables Large-Scale Study of Polar and Ionic Metabolites

Researchers from the McCullagh Group in Oxford University's Department of Chemistry have published an innovative method in Nature Protocols today (22 August) that provides comprehensive analysis of metabolites found in cells, tissues and biofluids.

22 Aug 2025

Cancer Cells Steal Energy from Fat to Fuel Growth

UCSF scientists caught cancer cells in the act of breaking into fat cells and releasing their fat. The energy heist seems to be critical for the growth of deadly breast cancer.

21 Aug 2025

New Insights Reveal Bacterial Roots of Key Plant Hormone Enzymes

Terpenoids play vital roles in plant ecology-from repelling pests to attracting pollinators-and are produced by terpene synthases (TPSs) enzymes.

19 Aug 2025

New Water-Based Method Extracts High-Purity Lignin

The Nanoscience Center at the University of Jyväskylä discovered that lignin, a polyphenol vital for plant structure, has an antimicrobial effect against viruses and bacteria.

13 Aug 2025

ISGlobal Develops HTGAnalyzer to Simplify Transcriptomic Data Analysis

The Barcelona Institute for Global Health (ISGlobal), a centre supported by the "la Caixa" Foundation, has launched HTGAnalyzer, a new, easy-to-use, fast and reproducible bioinformatics tool for advanced transcriptomic data analysis.

11 Aug 2025

Ribosome Levels Drop During Early Brain Development

A team led by UT Southwestern Medical Center scientists has identified a specific stage of neurodevelopment when differentiating neural cells produce fewer ribosomes, which are responsible for making proteins.

6 Aug 2025