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Study explores that extra dosages of genes may lead to surplus X chromosomes

One out of every 500 to 1,000 boys is born with one or more extra X chromosomes, which can cause a variety of symptoms as the extra chromosomes to including infertility, larger breasts, osteoporosis, diabetes, cardiac problems, intellectual incapacity, and cancer.

1 Apr 2022

Globins in the body help fight liver disease

Anti-fibrotic therapy is still a medical necessity in the treatment of chronic liver disease in humans. The anti-fibrotic activity of globin family members in hepatic stellate cells (HSCs), the principal cell type involved in liver fibrosis, was reported by a research group led by Professor Norifumi Kawada of Osaka Metropolitan University (OMU).

24 Mar 2022

Novel mechanistic insight into how gut bacteria work to tame intestinal inflammation

Bile acids made by the liver have long been known for their critical role in helping to absorb the food we ingest.

From Harvard Medical School 17 Mar 2022

New tools for measuring the biological ages of various organ systems

It's common to say that someone looks either younger or older than their chronological age, but aging is more than skin deep.

9 Mar 2022

T cells sometimes remain in the skin for years, research finds

Human immune cells not only circulate in the blood, but can also occupy certain tissues and sometimes remain there for years.

8 Mar 2022

Threespine stickleback fish study details how parasite resistance in hosts arises

They thrive everywhere from bustling cities to remote rainforests -; even in our own backyards. Pervasive and unapologetic mooches, parasites rely on other organisms for their survival.

3 Mar 2022

Intestinal cell changes are driven by the BMP signaling pathway, study finds

Intestinal cells can change specializations during their lives. The BMP signaling pathway – an important communication mechanism between cells – appears to be the driver of these changes.

2 Mar 2022

Microbes hindering cancer therapy seem to play a bigger role than helpful ones

Melanoma patients receiving therapy that helps their immune system kill cancer cells respond to treatment differently depending on the types of microbes in their gut, and new research suggests the microorganisms hindering therapy have more influence than the beneficial ones.

1 Mar 2022

Researchers create a regulatory map of zebrafish genome

The zebrafish is an important model organism for studying things like genetic diseases. A regulatory map of its genome has been successfully created using high-throughput experiments and AI methods, a team led by Uwe Ohler now reports in Cell Genomics and Nature Machine Intelligence.

25 Feb 2022

Experts explore how DNA packaging affects gene regulation

Russian researchers have elucidated the mechanisms involved in the activation of genes in drosophila fly sex cells.

24 Feb 2022

Recent study reveals the code involved in human gene regulation

The logic that handles gene regulation in human cells has been discovered by a team of researchers at the University of Helsinki.

24 Feb 2022

Study reveals the power of ketone bodies

The immune system has its cells all around the body, and they are constantly doing their work even if the body is in great shape.

22 Feb 2022

Experts identify critical genes that cause coronary heart disease and trigger heart attacks

Recent research identified the major genes involved in coronary heart disease and cardiac arrest.

21 Feb 2022

Experts identify a potential new target for antimalarial development

A protein that plays an important biological role in the malaria-causing parasite has been discovered by an international research team.

18 Feb 2022

Mortality of newborns on ECMO linked with red blood cell transfusion volume

Newborns in respiratory failure who require the life-sustaining support of ECMO also require transfusion of red blood cells. But a new study indicates that the higher volume of these oxygen-carrying blood cells the babies receive, the higher their mortality rate.

15 Feb 2022

Experts identify the master regulator of Nodal signaling in human embryonic stem cells

A new study has led to the discovery that the Hippo signaling effector YAP1 is a master controller of Nodal signaling in hESCs for a process crucial to human development.

14 Feb 2022

Pro-regenerative metabolite supports elevated tissue regeneration and delays aging, study reveals

Research recognizes uridine as a pro-regenerative metabolite that highlighted human stem cell activity and improved restructuring and tissue repair.

14 Feb 2022

A simple route for synthesizing fungal compound and its derivatives

The solutions to many of humanity's problems can be found within nature. For instance, who could have guessed that an antibiotic as powerful as penicillin would be found in a common mold, or that the drug aspirin would be derived from the bark of the willow tree?

From Tokyo University of Science 10 Feb 2022

Researchers build rapid-acting antidepressant compounds that are non-hallucinogenic

The World Health Organization estimates that nearly 280 million people worldwide suffer from depression.

2 Feb 2022

MIT researchers develop new way to deliver RNA in a capsule

Like most vaccines, RNA vaccines have to be injected, which can be an obstacle for people who fear needles. Now, a team of MIT researchers has developed a way to deliver RNA in a capsule that can be swallowed, which they hope could help make people more receptive to them.

1 Feb 2022