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Protein Plays Dual Role by Silencing Thousands of Genes While Keeping Vital Ones Active

The causes of male infertility can be hard to diagnose, with many tests failing to detect genetic defects. Sometimes, infertility doesn't even involve the genes themselves. It can arise from improper folding of the father's DNA in the sperm. If a couple conceives, this mispackaged DNA can damage the lifelong health of the child.

21 May 2026

Daily Grapes Intake Improves Skin Health Through Changes in Gene Expression

Clinical trials have shown that consumption of grapes can increase the resilience of skin to UV irradiation in about 30-50% of the subject population.

15 May 2026

Epigenetic Changes May Influence Inheritance Beyond DNA Sequence Alone

When we think about genetic inheritance, we usually leap to DNA, the four-letter code containing the instructions for building a living organism.

11 May 2026

New Genetic Pathways Linked to Cardiometabolic Disease Identified

A study published today in PLOS Medicine has identified two new genetic pathways that contribute to cardiometabolic disease, which includes heart disease, obesity and diabetes.

24 Apr 2026

Largest African Genomic Study Reveals New Kidney Disease Insights

An international research collaboration led by the University of the Witwatersrand and Queen Mary University of London has published the most comprehensive genomic investigation of kidney function ever conducted in African populations, shedding new light on the genetics of chronic kidney disease (CKD) across diverse African populations.

8 Apr 2026

Nonviral Nanoparticles Show Promise for Safer Gene Delivery Methods

In a demonstration that helps pave the way for gene therapies with fewer side effects, several human cell types were genetically modified with protein nanoparticles designed at University of Michigan Engineering and Michigan Medicine.

1 Apr 2026

EV Engineering Boosts Drug Delivery and Improves Sepsis Survival

The engineered scaffold protein EN144 significantly improves extracellular vesicle therapies, showing potential in sepsis treatment and targeted drug delivery.

18 Mar 2026

Single-Cell Atlas Reveals Coordinated Aging Across Multiple Organs

As we age with each passing year, we become more susceptible to chronic diseases like cancer, heart disease, and dementia.

27 Feb 2026

Study Reveals Cellular Blueprint of the Human Liver

Never-before-seen 3D reconstructions of human liver tissue have been created at a cellular level. The details obtained by a team of UW Medicine and University of Washington engineers and physicians capture the spatial microstructure of multiple lobes of this multitasking organ.

24 Feb 2026

AI-Designed CytoTape Records Cellular Events Over Time With High Resolution

Unraveling the mysteries of how biological organisms function begins with understanding the molecular interactions within and across large cell populations.

27 Jan 2026

Protein Translation Enzyme Governs Macrophage Maturation and Tissue Homeostasis

A new study led by researchers at the Johns Hopkins Kimmel Cancer Center, its Bloomberg~Kimmel Institute for Cancer Immunotherapy and the Johns Hopkins Bloomberg School of Public Health found that an enzyme involved in protein translation is essential for circulating immune cells, called monocytes, to mature into tissue-resident macrophages, a specialized population of immune cells that maintain organ health by clearing dead cells and debris.

24 Jan 2026

DHPS Enzyme Deficiency Impairs Macrophage Development and Tissue Repair

22 Jan 2026

Hidden Sperm RNA Remodeling With Age May Impact Next Generation

Increasing paternal age has been linked to elevated health risks for the next generation, including higher risks of obesity and stillbirth. But what drives this increased risk remains unknown.

21 Jan 2026

Genetic Study Links Expanding DNA Repeats to Aging and Disease Risk

An analysis of genetic data from over 900,000 people shows that certain stretches of DNA, made up of short sequences repeated over and over, become longer and more unstable as we age.

8 Jan 2026

Genes Can Spread Their Effects Through Shared Microbes

Your "roommate's" genes could be influencing the bacteria living in your gut, and vice versa, according to a study of rats published today in Nature Communications.

19 Dec 2025

Specific Gut Bacteria Found to Control Weight and Blood Fat Levels

The gut microbiome is intimately linked to human health and weight. Differences in the gut microbiome-the bacteria and fungi in the gut-are associated with obesity and weight gain, raising the possibility that changing the microbiome could improve health.

17 Dec 2025

Researchers Elucidate Microtubule-Mediated Cell Signal Transduction

The most diverse functions of a cell in the human body – from cell division and differentiation to motility and programmed cell death – are controlled by signaling proteins within the cell. This includes the immune system and the reading of genetic information.

11 Dec 2025

Engineered Gut Bacteria With MiRNA Nanoparticles To Reverse IBD

Biomimetic nanoparticles delivering microRNA to gut bacteria enhance protective metabolites, repair intestinal barriers, and alleviate colitis symptoms.

3 Dec 2025

Study Identifies Adipogenin as Crucial Driver of Lipid Droplet Formation

A microprotein called adipogenin appears to play a key role in helping fat cells store lipid droplets – a phenomenon that's pivotal for metabolic health, a study co-led by UT Southwestern Medical Center researchers shows.

27 Nov 2025

New Polygenic Risk Scores Transform Disease Prediction for Han Chinese Populations

Researchers at Academia Sinica have developed the first population-specific polygenic risk score (PRS) models for people of Han Chinese ancestry, achieving unprecedented accuracy in predicting risks for common diseases such as diabetes, heart disease, autoimmune disorders.

22 Nov 2025