Neurodegenerative Diseases News and Research

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Advanced Sequencing Uncovers Cause of Rare Mitochondrial Encephalopathy

Mitochondrial diseases are among the most prevalent hereditary metabolic disorders, known to occur in one out every 5000 births.

19 Nov 2024

New Mechanism for Precise Protein Production Unveiled

A new process that is essential to the synthesis of cellular proteins has been discovered by an international research team.

15 Nov 2024

Novel Approach to Combat Protein-Related Diseases

Researchers from Mainz and Leiden universities have devised a simple model system that can be used to break down fibrils, the cause of several diseases like Alzheimer's and Parkinson's disease, into their constituent single units or liquid droplets.

14 Nov 2024

How Neuroimmune Cells Modulate Immune Responses and Neuroinflammation

The brain, traditionally considered an immune-privileged organ due to the blood-brain barrier (BBB), has its own sophisticated immune defense system.

7 Nov 2024

A New Statistical Method to Mitigate AI Bias in Genetic Research

Researchers at the University of Wisconsin–Madison are cautioning that the growing use of artificial intelligence techniques in genetics and medicine may result in incorrect inferences regarding the relationship between genes and physical traits, such as risk factors for diseases like diabetes.

5 Nov 2024

MicroQuin's Space Research Paves Way for Potential Cancer Treatment

In October, we think pink, and for a good reason—one out of every eight women will be diagnosed with breast cancer in their lifetime, and each year, 2 million women are given this frightening diagnosis.

4 Nov 2024

New Insights into the Mechanism of Glycan Branch Formation

Glycans are sugar chains that bind to cells via proteins or lipids, altering their chemical properties

30 Oct 2024

C. elegans Model Revolutionizes Search for Amyloid Inhibitors

An international team led by researchers at the University of Toronto has developed an efficient and robust system, using the C. elegans nematode, to screen for compounds that can stop the growth of amyloid proteins.

29 Oct 2024

Study Uncovers How MANF Protein Enhances Cellular Homeostasis and Longevity

McMaster University researchers have discovered a previously unknown cell-protecting function of a protein, which could open new avenues for treating age-related diseases and lead to healthier aging overall.

21 Oct 2024

A Novel Regulator of RNA Processing in Alzheimer's Disease

A research team from the University of Barcelona's Institute of Neurosciences described a novel molecular mechanism that modifies the process of protein synthesis and impacts RNA processing in Alzheimer's patients' brains.

21 Oct 2024

MANF Protein Found to Boost Cellular Clean-Up and Efficiency

Researchers at McMaster University have uncovered a previously unrecognized function of a protein that helps protect cells, potentially leading to new treatments for age-related conditions and promoting healthier aging.

18 Oct 2024

Researchers Develop Fluorescent Biosensor to Study PKC Activity

Working in organoid models, researchers at University of California San Diego School of Medicine have developed a new tool to study protein-kinase C (PKC) enzymes, which play a critical role in cell growth, differentiation and survival.

14 Oct 2024

Study Unravels the Mystery of Hsp70 Chaperones

Proteins control most of the body's functions, and their malfunction can have severe consequences, such as neurodegenerative diseases or cancer. Therefore, cells have mechanisms in place to control protein quality.

9 Oct 2024

Scientists Uncover Secrets of Circadian Rhythm Control

Scientists from Duke-NUS Medical School and the University of California, Santa Cruz, have discovered the secret to regulating our internal clock.

8 Oct 2024

Two Alzheimer’s Genetic Risk Factors Trigger Harmful Inflammation in Females

Weill Cornell Medicine investigators have found that two genetic variants that confer high risk of Alzheimer's disease (AD) together trigger a harmful inflammatory response in the brain's immune cells, particularly in females, in a preclinical model.

1 Oct 2024

Gut Bacteria Influence Hormonal Balance and Hypopituitarism Symptoms in Mice

Researchers at the Francis Crick Institute have shown that the balance of bacteria in the gut can influence symptoms of hypopituitarism in mice.

27 Sep 2024

Sodium Transport Found to Play a Surprising Role in Mitochondrial Energy Production

The GENOXPHOS (Functional Genetics of the Oxidative Phosphorylation System) group at the Centro Nacional de Investigaciones Cardiovasculares (CNIC) has discovered a crucial role of sodium in the generation of cellular energy.

20 Sep 2024

UChicago Team Secures $7.4 Million Grant to Study Cellular Adaptation

Cells use a variety of processes to adapt to changes and stressors in their environment, like increased temperature.

21 Aug 2024

Rapid Parkinson's Model Opens Door to Personalized Treatments

Scientists at Brigham and Women’s Hospital, a key member of the Mass General Brigham healthcare system, have created a model that swiftly transforms stem cells into brain cells exhibiting protein structures associated with Parkinson’s disease (PD).

30 Jul 2024

Traffic-Related Ultrafine Particles Cause Mitochondrial Dysfunction in Olfactory Mucosa

Ultrafine particles, UFPs, the smallest contributors to air pollution, hinder the function of mitochondria in human olfactory mucosa cells, a new study shows.

25 Jul 2024