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AI-Guided Protein Engineering Creates Smart Receptors for Cancer Immunotherapy

Cancer immunotherapy, especially using T cells, is showing a lot of promise in treating blood cancers. Bioengineered T cells, especially those equipped with chimeric antigen receptors (CAR-T cells), have revolutionized cancer treatment.

29 Oct 2025

AI-Powered Approach Boosts Protein Production Efficiency in E. coli

Proteins sourced from microorganisms are attracting attention for their potential in biomanufacturing a variety of products, including pharmaceuticals, industrial enzymes, and diagnostic antibodies.

29 Oct 2025

Light-Based Sensor Continuously Detects Vaccine Quality

A group of researchers from Purdue University and Merck & Co. Inc., referred to as Merck Sharp & Dohme Corp. in regions outside the U.S. and Canada, has recently unveiled a novel analytical tool that may assist pharmaceutical companies in enhancing vaccine production through expedited monitoring and analysis.

29 Oct 2025

Retinal Implant Restores Sight for Patients With Macular Degeneration

A wireless photovoltaic implant shows promise in restoring central vision for patients with macular degeneration, enhancing visual acuity and independence.

29 Oct 2025

Researchers Discover Novel Clubroot Resistance Gene Crr5 in Chinese Cabbage

Clubroot disease, caused by Plasmodiophora brassicae, is a devastating soil-borne pathogen that severely threatens global production of cruciferous crops.

28 Oct 2025

Discovery of Hidden Antibiotic Offers Hope in the Fight Against Superbugs

Chemists from the University of Warwick and Monash University have discovered a promising new antibiotic that shows activity against drug-resistant bacterial pathogens, including MRSA and VRE.

28 Oct 2025

Aptamer Technology Offers Breakthrough in Identifying Zombie Cells

When it comes to treating disease, one promising avenue is addressing the presence of senescent cells.

28 Oct 2025

Electromagnetic Levitation Enables Noninvasive Sorting of Cancer and Healthy Cells

Stanford Medicine researchers invent an electromagnetic device that can gently sort different types of cells by levitating them to different heights.

28 Oct 2025

Mutation in NAMPT Gene Found to Cause Rare Neurological Disease

An international research team, led by Shinghua Ding at the University of Missouri, has identified a previously unknown genetic disease that affects movement and muscle control.

28 Oct 2025

Discovery of Glucocorticoid Receptor Multimerization Opens Path to Safer Therapies

Drugs to treat inflammatory and autoimmune diseases - such as asthma, psoriasis, rheumatoid arthritis or Chrousos syndrome - act mainly through the glucocorticoid receptor (GR).

28 Oct 2025

TRF1 Knockout Mice Exhibit Healthier Metabolic States Without Telomere Shortening

A new research paper was published in Volume 17, Issue 9 of Aging-US on September 17, 2025, titled "Depletion of the TRF1 telomere-binding protein leads to leaner mice with altered metabolic profiles."

28 Oct 2025

Rhizosphere Metabolites Play Key Role in Regulating the Distribution of Antibiotic Resistance Genes

Their study reveals that rhizosphere metabolites-substances secreted by plant roots-play a crucial role in regulating the distribution of manure-derived ARGs in both the soil and plant tissues.

27 Oct 2025

Enhancing Ovarian Cancer Treatment with Multi-Modal Immunotherapy Approach

Results of a study led by researchers at Roswell Park Comprehensive Cancer Center show that combining two types of immunotherapy - engineered T cells that secrete bispecific T cell engagers (BiTEs) and an immune checkpoint inhibitor - can alter the tumor microenvironment to launch a stronger attack against ovarian cancer and reduce the risk of relapse.

27 Oct 2025

First Chromosome-Scale Genome Assembly of Blackcurrant Reveals Drought Adaptation Strategies

Drought stress disrupts plant growth, metabolism, and reproduction, with devastating effects on crop productivity worldwide.

27 Oct 2025

Mitochondria and Lysosomes Orchestrate Metabolic States of Regulatory T Cells

Metabolism guides the activation states of regulatory T cells, the immune cells that prevent inappropriate activation of the immune system.

27 Oct 2025

Simple Genetic Switch can Underlie Temperature-Mediated Plasticity in Butterfly Wing Patterns

Scientists from the National University of Singapore (NUS) have discovered a simple DNA "switch" that helps tropical butterflies adjust the size of their wing eyespots in response to seasonal temperatures, shedding light on the evolution of environmental sensitivity.

27 Oct 2025

Understanding Interplay of Physiological Processes as the Brain Shifts from Wakefulness to Sleep

Findings from Mass General Brigham investigators highlight the intricate interplay of diverse physiological processes as the brain shifts from wakefulness to sleep.

27 Oct 2025

Study Reveals How TR4 Fungus Silences Banana Defense Genes

Bananas rank among the world's most valuable staple crops, yet their production faces severe losses from Fusarium wilt caused by Fusarium oxysporum f. sp. cubense (Foc) tropical race 4 (TR4).

24 Oct 2025

RNA-Based Molecular Switch Enhances Disease Resistance in Pears

In recent years, scientists have uncovered the remarkable regulatory power of long non-coding RNAs (lncRNAs) - RNA molecules once dismissed as "genetic dark matter."

24 Oct 2025

Disrupted Circadian Rhythms Alter Gene Activity in Alzheimer’s Disease

Alzheimer's disease is notorious for scrambling patients' daily rhythms. Restless nights with little sleep and increased napping during the day are early indicators of disease onset, while sundowning, or confusion later in the day, is typical for later stages of the disease.

24 Oct 2025

Research News and Research

AI-Guided Protein Engineering Creates Smart Receptors for Cancer Immunotherapy

AI-Powered Approach Boosts Protein Production Efficiency in E. coli

Light-Based Sensor Continuously Detects Vaccine Quality

Retinal Implant Restores Sight for Patients With Macular Degeneration

Researchers Discover Novel Clubroot Resistance Gene Crr5 in Chinese Cabbage

Discovery of Hidden Antibiotic Offers Hope in the Fight Against Superbugs

Aptamer Technology Offers Breakthrough in Identifying Zombie Cells

Electromagnetic Levitation Enables Noninvasive Sorting of Cancer and Healthy Cells

Mutation in NAMPT Gene Found to Cause Rare Neurological Disease

Discovery of Glucocorticoid Receptor Multimerization Opens Path to Safer Therapies

TRF1 Knockout Mice Exhibit Healthier Metabolic States Without Telomere Shortening

Rhizosphere Metabolites Play Key Role in Regulating the Distribution of Antibiotic Resistance Genes

Enhancing Ovarian Cancer Treatment with Multi-Modal Immunotherapy Approach

First Chromosome-Scale Genome Assembly of Blackcurrant Reveals Drought Adaptation Strategies

Mitochondria and Lysosomes Orchestrate Metabolic States of Regulatory T Cells

Simple Genetic Switch can Underlie Temperature-Mediated Plasticity in Butterfly Wing Patterns

Understanding Interplay of Physiological Processes as the Brain Shifts from Wakefulness to Sleep

Study Reveals How TR4 Fungus Silences Banana Defense Genes

RNA-Based Molecular Switch Enhances Disease Resistance in Pears

Disrupted Circadian Rhythms Alter Gene Activity in Alzheimer’s Disease

Driving Support for Pharmaceutical Testing Through Continuous Innovation

From Memory to Metaplasticity: Unraveling the Brain's Secrets

Revolutionizing Mass Spectrometry: A Deep Dive into Plasmion’s SICRIT® Technology

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