Embryo News and Research

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Researchers Identify Proteins to Reprogram Fibroblasts into Limb Progenitor Cells

In a collaborative study, researchers from Kyushu University and Harvard Medical School have identified proteins that can turn or "reprogram" fibroblasts -; the most commonly found cells in skin and connective tissue -; into cells with similar properties to limb progenitor cells.

5 Mar 2024

Scientists Develop First Full Model of Early Human Central Nervous System with Stem Cells

The first stem cell culture method that produces a full model of the early stages of the human central nervous system has been developed by a team of engineers and biologists at the University of Michigan, the Weizmann Institute of Science, and the University of Pennsylvania.

27 Feb 2024

New ACMG Statement Urges Caution with Polygenic Risk Score Testing in Embryo Selection

Should we be using polygenic risk score assessment for embryo selection? Providing in-depth analysis, the Social, Ethical and Legal Issues Committee of the American College of Medical Genetics and Genomics (ACMG) has released a new Points to Consider statement to assist healthcare professionals and patients in understanding the safety and utility of preimplantation genetic testing for polygenic disorders (PGT-P) as a clinical service.

26 Feb 2024

‘Mini-Placentas’ Help Scientists Study the Causes of Pre-eclampsia and Pregnancy Disorders

Scientists have grown ‘mini-placentas’ in the lab and used them to see how the placenta develops and interacts with the inner lining of the womb – findings that could help scientists better understand and, in future, potentially treat pre-eclampsia.

17 Jan 2024

Novel Zebrafish Model Offers Efficient Tool for Norovirus Research

Food virologists from the National University of Singapore (NUS) have successfully propagated the human norovirus using zebrafish embryos, providing a valuable platform to assess the effectiveness of virus inactivation for the water treatment and food industries.

2 Jan 2024

Zebrafish Embryo Model Unveils Breakthrough Cultivation Method

Researchers at the National University of Singapore (NUS) specializing in food virology have achieved successful cultivation of the human norovirus using zebrafish embryos.

29 Dec 2023

How 3D DNA Architecture Shapes Cell Fate in Early Embryos

The intricate process of duplicating genetic information, referred to as DNA replication, lies at the heart of the transmission of life from one cell to another and from one organism to the next. This happens by not just simply copying the genetic information; a well-orchestrated sequence of molecular events has to happen at the right time.

21 Dec 2023

Microbial Sensor Unlocks Path to Personalized Blood Stem Cell Therapy

A microbial sensor that helps identify and fight bacterial infections also plays a key role in the development of blood stem cells, valuable new insight in the effort to create patient-derived blood stem cells that could eliminate the need for bone marrow transplants.

21 Dec 2023

Microbial Sensor Plays Key Role in Blood Stem Cell Development

20 Dec 2023

New Cell Model Paves Way for Faster Treatments for Neuromuscular Diseases

Scientists have so far identified around 800 different neuromuscular diseases. These conditions are caused by problems in the way muscle cells, motor neurons and peripheral cells interact.

20 Dec 2023

Mathematical Models and Biological Dynamics in Embryo Development

One of life’s enduring fundamental questions revolves around the process of development. Consider human growth—how do cells autonomously arrange themselves into structures like skin, muscles, or bones? How do they coalesce to form intricate organs such as the brain, fingers, or spine?

7 Dec 2023

Wilmot Researchers Uncover a "Genomic Tug of War" That Influences Decitabine's Effectiveness

Some patients with myelodysplastic syndromes, like acute myeloid leukemia, benefit from a chemotherapy drug called decitabine that stunts cancer growth. But many others are resistant to decatibine's effects or become resistant over time.

17 Nov 2023

New Synthetic Enzymes can Control Signaling Protein Vital to Embryonic Development

A University of Texas at Dallas bioengineer has developed synthetic enzymes that can control the behavior of the signaling protein Vg1, which plays a key role in the development of muscle, bone and blood in vertebrate embryos.

10 Nov 2023

New Atlases Reveal Unprecedented Detail of the Human Brain

In two concurrent projects, scientists at the Karolinska Institutet have played a significant role in producing the most extensive atlases of human brain cells to date.

13 Oct 2023

The Powerful Limb Regeneration Capabilities of Axolotl

Researchers from EPFL shed light on the axolotl’s unrivaled limb regeneration ability, contradicting long-held assumptions and providing fresh insights into possible mammalian limb restoration.

12 Oct 2023

Towards A Better Understanding of Early Human Embryonic Development

Despite being an essential developmental process, the understanding of human embryonic genome activation is limited, owing to the lack of in vitro cell models and ethical concerns.

22 Sep 2023

DiNP Exposure in Early Pregnancy May Cause Birth Defects

We are constantly exposed to phthalates in our environment through plastic products such as storage containers, medical devices, packages, fabrics, and toys. Specifically, di-isononyl phthalate is inevitably becoming a part of our lives. Unfortunately, the impact of DiNP on the establishment and maintenance of pregnancy is largely unknown. In a new study, researchers used mice to understand how DiNP affects pregnancy.

4 Sep 2023

Embryo News and Research

Researchers Identify Proteins to Reprogram Fibroblasts into Limb Progenitor Cells

Scientists Develop First Full Model of Early Human Central Nervous System with Stem Cells

New ACMG Statement Urges Caution with Polygenic Risk Score Testing in Embryo Selection

‘Mini-Placentas’ Help Scientists Study the Causes of Pre-eclampsia and Pregnancy Disorders

Novel Zebrafish Model Offers Efficient Tool for Norovirus Research

Zebrafish Embryo Model Unveils Breakthrough Cultivation Method

How 3D DNA Architecture Shapes Cell Fate in Early Embryos

Microbial Sensor Unlocks Path to Personalized Blood Stem Cell Therapy

Microbial Sensor Plays Key Role in Blood Stem Cell Development

New Cell Model Paves Way for Faster Treatments for Neuromuscular Diseases

Mathematical Models and Biological Dynamics in Embryo Development

Wilmot Researchers Uncover a "Genomic Tug of War" That Influences Decitabine's Effectiveness

New Synthetic Enzymes can Control Signaling Protein Vital to Embryonic Development

New Atlases Reveal Unprecedented Detail of the Human Brain

The Powerful Limb Regeneration Capabilities of Axolotl

Towards A Better Understanding of Early Human Embryonic Development

DiNP Exposure in Early Pregnancy May Cause Birth Defects

Scientists Discover Secret of Virgin Birth, and Switch on the Ability in Female Flies

New Method Creates Embryo-Like Structure That Mimics Gastrulation

The Function of Stem Cell Barriers in the Treatment of Fertility

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Driving Support for Pharmaceutical Testing Through Continuous Innovation

From Memory to Metaplasticity: Unraveling the Brain's Secrets

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