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MYC Gene's Dual Role in Cancer Growth and Immune Suppression

The cancer gene MYC camouflages tumors by suppressing alarm signals that normally activate the immune system.

24 Jan 2026

Protein Translation Enzyme Governs Macrophage Maturation and Tissue Homeostasis

A new study led by researchers at the Johns Hopkins Kimmel Cancer Center, its Bloomberg~Kimmel Institute for Cancer Immunotherapy and the Johns Hopkins Bloomberg School of Public Health found that an enzyme involved in protein translation is essential for circulating immune cells, called monocytes, to mature into tissue-resident macrophages, a specialized population of immune cells that maintain organ health by clearing dead cells and debris.

24 Jan 2026

Coordinated Gene Regulation Drives Saponin Production

Triterpenoid saponins are widely valued for their diverse pharmacological activities and also play important defensive roles in plants.

22 Jan 2026

DHPS Enzyme Deficiency Impairs Macrophage Development and Tissue Repair

22 Jan 2026

Yeast-Based Platform Achieves Animal-Free High Quality Chondroitin Sulfate

By systematically redesigning multiple metabolic modules inside Komagataella phaffii, the researchers achieved both high product yield and high sulfation quality, two goals that have long been difficult to reach at the same time.

21 Jan 2026

First Fully Synthetic Bacteriophage Engineering System for Antibiotic-Resistant Bacterium

Bacteriophages have been used therapeutically to treat infectious bacterial diseases for over a century.

21 Jan 2026

How Far-Red Light Stops Biofilms in Drug-Resistant Bacteria

Light is a fundamental signal affecting every form of life. Cycles of light and dark help set the biological clocks in organisms from unicellular bacteria to humans.

21 Jan 2026

Replacing Large Mouse Gene Regions with Human DNA

Humanized mouse models are essential for investigating human gene function; however, the complete replacement of mouse genes with entire human sequences has posed significant technical challenges.

19 Jan 2026

Backyard Soil Bacterium Produces Antibiotic Built to Outsmart Resistance

Early in 2025, scientists discovered a promising new antibiotic in a soil sample from a lab technician's backyard.

16 Jan 2026

Fly Pigmentation Study Uncovers Genes Influencing Dopamine, Sleep, and Movement

Dopamine in the brain influences movement, learning, motivation and sleep. In humans, problems with dopamine are linked to conditions like Parkinson's disease, depression and sleep disorders.

14 Jan 2026

Marsupial Gut Microbiomes Show Diet Adaptations, Antibiotic Resistance Risks

Marsupials are a group of mammals that encompass many of Australia's most iconic animals, unique because of their geographically isolated evolution.

14 Jan 2026

Giant Virus with A Massive Genome and Unusual Infection Strategy

Ushikuvirus, a newly identified giant virus, showcases unique cytopathic effects and structural features, enhancing knowledge of viral evolution and diversity.

14 Jan 2026

Synthetic RNA Platform Converts Viral Replication Into Detectable Cellular Signals

The technology, called the Viral-Engineered RNA-based Activation System (VERAS), hijacks the virus's own replication machinery to switch on reporter or therapeutic genes precisely in infected cells.

9 Jan 2026

Deep Learning–Based Codon Optimization Framework Boosts Protein Expression in E. coli

By combining Transformer-based sequence modeling with a novel conditional probability strategy, the approach overcomes long-standing trade-offs between maximizing expression metrics and maintaining translational features critical for proper protein folding.

9 Jan 2026