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Researchers isolate fragile protein complex from heat-loving bacteria

Researchers isolate fragile protein complex from heat-loving bacteria

Goethe University scientists have discovered what is probably the oldest enzyme found in cellular respiration. Now, the team has successfully isolated a highly delicate protein complex known as “Rnf” from the heat-loving bacterium called Thermotoga maritima.

10 Aug 2020

Small, compact Cas proteins found in bacteriophages are ideal for gene editing

Small, compact Cas proteins found in bacteriophages are ideal for gene editing

The DNA-cutting proteins central to CRISPR-Cas9 and related gene-editing tools originally came from bacteria, but a newfound variety of Cas proteins apparently evolved in viruses that infect bacteria.

20 Jul 2020

Hypercompact CRISPR enzyme from bacteriophages expands genome editing toolbox

Hypercompact CRISPR enzyme from bacteriophages expands genome editing toolbox

A recently discovered hypercompact CRISPR enzyme found only in huge bacteriophages, and known as CRISPR-CasΦ, is functional, a new study by Patrick Pausch, Jennifer Doudna and colleagues reports, and it provides a powerful new tool in the CRISPR genome editing toolbox, including because it can target a wider range of genetic sequences compared to Cas9 and Cas12

17 Jul 2020

Biophysicists shed light on how optogenetic tool works

Biophysicists shed light on how optogenetic tool works

An international research team has for the first time obtained the structure of the light-sensitive sodium-pumping KR2 protein in its active state.

29 May 2020

Single-cell gene expression studies can shed more light on disrupted genes

Single-cell gene expression studies can shed more light on disrupted genes

Scientists can gain a better understanding of the cellular roles of the disrupted gene by disturbing the expression of a specific gene and tracking how this change has an impact on the expression of other types of genes.

13 May 2020

Biophysicists uncover new features of molecular elevator

Biophysicists uncover new features of molecular elevator

Biophysicists from the Moscow Institute of Physics and Technology and the University of Groningen in the Netherlands have visualized a nearly complete transport cycle of the mammalian glutamate transporter homolog from archaea.

21 Apr 2020

Study discovers hydrogen cycling in the Acetobacterium woodii bacterium

Study discovers hydrogen cycling in the Acetobacterium woodii bacterium

At Goethe University Frankfurt, microbiologists have unraveled the mechanism of hydrogen use by the bacterium Acetobacterium woodii for energy conservation.

31 Mar 2020

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