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Method Seeks to Eliminate the Need for Frozen mRNA Vaccines

CEPI has provided funding to a public research university in Belgium to investigate whether a novel vaccine stabilization method could eliminate the need for mRNA vaccines to be stored in frozen storage and enable a quick and expanded response to future outbreaks in as little as 100 days.

14 Mar 2024

NIH Researchers Map Vulnerable Sites on Epstein-Barr Virus gp42 Protein

Studies of interactions between two lab-generated monoclonal antibodies (mAbs) and an essential Epstein-Barr virus (EBV) protein have uncovered targets that could be exploited in designing treatments and vaccines for this extremely common virus.

13 Mar 2024

Genomic Study Warns of H5N1 Adaptation to Marine Mammals

The highly pathogenic avian influenza virus H5N1 has adapted to spread between birds and marine mammals, posing an immediate threat to wildlife conservation, according to a study from the University of California, Davis, and the National Institute of Agricultural Technology (INTA) in Argentina.

29 Feb 2024

Study Identifies Novel Enzyme Crucial for Bacterial Cell Wall Integrity

Researchers at Umeå University in Sweden, led by Professor Felipe Cava, have identified a new family of enzymes that creates a unique type of cross-linking between the building blocks of bacterial cell walls.

20 Feb 2024

Induction Cooktop Technology Shows Promise in Reducing Bacterial Infection in Prosthetic Joints

The same technology at work in induction cooktops cut the amount of bacteria present in a prosthetic joint infection when used in conjunction with antibiotics in a mouse model, UT Southwestern Medical Center researchers report in a new study.

19 Feb 2024

GWAS Identifies Key Genetic Factors for Lassa Fever Susceptibility and Severity

While combing through the human genome in 2007, computational geneticist Pardis Sabeti made a discovery that would transform her research career.

9 Feb 2024

Immune System Surprise: "Junk Cells" Show Ability to Fight Malaria

Researchers from The Australian National University (ANU) have discovered a previously unknown ability of a group of immune system cells, known as Atypical B cells (ABCs), to fight infectious diseases such as malaria.

9 Feb 2024

Decoding Virus-Host Tug-of-War with RNA-Protein Interaction Mapping

The interplay between ribonucleic acid (RNA) and proteins is not only important for maintaining cellular homeostasis but is also at the center of the tug-of-war between virus and host.

2 Feb 2024

Gut Bacteria Shape Our Defense Against Respiratory Viral Infections

The composition of microbiota found in the gut influences how susceptible mice are to respiratory virus infections and the severity of these infections, according to researchers from the Center for Translational Antiviral Research in the Institute for Biomedical Sciences at Georgia State University.

31 Jan 2024

Boosting Central Memory T Cells with Targeted Protein Modulation

The Hackensack Meridian Center for Discovery and Innovation's (CDI) Xue Lab has made yet another advancement in the understanding of the immune system and its potential for disease-fighting modulation.

22 Jan 2024

Ancient DNA Reveals Reason for High Multiple Sclerosis and Alzheimer’s Rates in Europe

Researchers have created the world’s largest ancient human gene bank by analysing the bones and teeth of almost 5,000 humans who lived across western Europe and Asia up to 34,000 years ago.

10 Jan 2024

Bacterial “Barcode” Deciphers the Fate of Proteins, Impacting Pathogen Behavior

Researchers at McMaster University have found a molecular “barcode” system that pathogenic bacteria use to identify harmful from beneficial molecules.

9 Jan 2024

mEnrich-seq: A High-Specificity Bacterial Enrichment Technique for Microbiome Research

In a landmark study recently published in the journal Nature Methods, researchers at the Icahn School of Medicine at Mount Sinai have unveiled mEnrich-seq-;an innovative method designed to substantially enhance the specificity and efficiency of research into microbiomes, the complex communities of microorganisms that inhabit the human body.

5 Jan 2024

AI-Powered Drug Breakthrough: Insilico Unveils Potent FGFR2/3 Inhibitor for Solid Tumors

Insilico Medicine, a generative artificial intelligence (AI)-driven clinical-stage drug discovery company, today announced the nomination of ISM8001, a novel molecule targeting FGFR2/3 for the treatment of tissue-agnostic solid tumors bringing the total number of PCCs nominated in 2023 to six.

29 Dec 2023

How Next-Gen Sequencing is Revolutionizing Infection Diagnosis

Scientists from Necker-Enfants Malades Hospital (AP-HP), the Institut Pasteur, Université Paris Cité, Inserm, Université Paris-Est Créteil and the Alfort National Veterinary School, coordinated by Professor Marc Eloit and Dr. Anne Jamet in collaboration with Dr. Jacques Fourgeaud and Beatrice Regnault, studied the role of global genetic characterization of samples (or non-targeted metagenomics) using next-generation sequencing (mNGS) in diagnosing infections.

19 Dec 2023

Breakthrough Research in Leishmaniasis Reveals Pain-Suppression Pathways

For the first time, scientists have begun to figure out why the disfiguring skin lesions caused by cutaneous leishmaniasis don't hurt.

1 Dec 2023

SMART Researchers Pioneer Novel Microfluidic Method to Optimize Bone Marrow Stem Cell Extraction for Advanced Cell Therapies

Researchers from the Critical Analytics for Manufacturing Personalized-Medicine (CAMP) Interdisciplinary Research Group (IRG) of Singapore-MIT Alliance for Research and Technology (SMART), MIT’s research enterprise in Singapore, in collaboration with the Agency for Science, Technology and Research (A*STAR) Bioprocessing Technology Institute (BTI) and National University Health System (NUHS), have developed a groundbreaking technology.

22 Nov 2023