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Researchers develop first biohybrid model of human ventricles with helically aligned beating cardiac cells

Heart disease -; the leading cause of death in the U.S. -; is so deadly in part because the heart, unlike other organs, cannot repair itself after injury.

11 Jul 2022

Healthy people can reap mental health benefits from gardening

Many longtime gardeners will tell you that the garden is their happy place. New research suggests that many people may indeed reap mental health benefits from working with plants -; even if they've never gardened before.

7 Jul 2022

Research highlights the new genetic variations and pediatric NAFLD severity

A multidisciplinary group of researchers at the University of California San Diego School of Medicine have advanced investigations into the genetic causes of NAFLD in children.

1 Jul 2022

Bone growth protein may help treat newborns with rare genetic lung condition

When babies are born with alveolar capillary dysplasia with misalignment of pulmonary veins (ACDMPV), their skin starts to turn blue from the under-oxygenated blood in their systems.

22 Apr 2022

Astrocyte abnormalities may play a pivotal role in causing ASD symptoms

Abnormalities in a type of brain cell called astrocytes may play a pivotal role in causing some behavioral symptoms of autism spectrum disorders, according to a preclinical study by Weill Cornell Medicine investigators.

22 Apr 2022

Scientists identify factors that regulate the development of brain cells in a specific order

Researchers have identified the complete series of 10 factors that regulate the development of brain cell types in the visual system of fruit flies-; including in what order these neurons develop.

From New York University (NYU) 7 Apr 2022

Experimental "gene silencing" therapy reduces a important driver of heart disease risk by up to 98%

Findings from a new Cleveland Clinic-led phase 1 trial show that an experimental "gene silencing" therapy reduced blood levels of lipoprotein(a), a key driver of heart disease risk, by up to 98%.

4 Apr 2022

New BGI research lays groundwork for organ regeneration

Scientists declared the invention of a transgene-free and manageable method to transform pluripotent stem cells into bona fide 8-cell totipotent embryo-like cells.

23 Mar 2022

Proteins surrounding organs and tissues switch off natural killer cells’ “killer” function, study finds

Natural killer (NK) cells, which are part of the body’s innate, or first-line, immune response, interact with tumor cells, viral infections, and solid organ transplants, according to a new study.

21 Mar 2022

ISU researchers receive major funding to go forward on blood stem cells research

For years, scientists have been unable to create a patient’s blood cells to cure blood illnesses, but a recently implemented federal funding might help IOWA State University researchers take important steps toward making that prospect a reality.

21 Mar 2022

Experts explore how DNA packaging affects gene regulation

Russian researchers have elucidated the mechanisms involved in the activation of genes in drosophila fly sex cells.

24 Feb 2022

Infusion of intestinal organoids to replace damaged intestinal tissue

Ulcerative colitis is an inflammatory bowel disease (IBD) that causes inflammation and ulcers (sores) in the digestive tract. Ulcerative colitis affects the innermost lining of the colon and rectum.

11 Feb 2022

Scientists on the verge of understanding how climate adaptation happens in plants

A century after scientists first noted that the environment contributes to the evolution of adaptive differences among plant populations, scientists are on the verge of figuring out how that adaptation happens -; by combining results from huge "common garden" experiments with genomic sequencing.

From Penn State University 9 Feb 2022

Kras oncogenes use genetic reprogramming to drive tumorigenesis

Cancerous tumors are made up of rapidly growing, abnormally shaped, cells that can infiltrate and destroy healthy tissues, travel to other parts of the body, and form additional tumors.

8 Feb 2022

Scientists discover families of proteins that could predict organ transplant rejection

Northwestern University scientists have discovered families of proteins in the body that could potentially predict which patients may reject a new organ transplant, helping inform decisions about care.

28 Jan 2022

Experts develop Immuno-CRISPR assay to detect kidney transplant complications

Doctors monitor kidney transplant recipients for signs of rejection in several ways, including biopsy.

7 Jan 2022

Biochemical signals sent from cell to cell play a key role in deciding their fate

Scientists have found a way to prove that biochemical signals sent from cell to cell play an important role in determining how those cells develop.

24 Dec 2021

Discovery may lead to a better understanding of prion and other neurodegenerative diseases

Prion diseases, such as Creutzfeldt-Jakob Disease (CJD), are fast-moving, fatal dementia syndromes associated with the formation of aggregates of the prion protein, PrP.

23 Dec 2021

300 million grant enables the establishment of new international stem cell research center

A grant from the Novo Nordisk Foundation of up to 300 million euro now enables the establishment of a major international research center focused on stem cell medicine.

20 Dec 2021

High-risk lymphoma patients may receive durable benefit from axi-cel CAR T cell therapy

Three clinical studies led by researchers at The University of Texas MD Anderson Cancer Center demonstrated enhanced responses for patients with high-risk lymphoma treated with axicabtagene ciloleucel (axi-cel) chimeric antigen receptor (CAR) T cell therapy.

13 Dec 2021