Central Nervous System News and Research

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Interactions between plasma miRNAs and cognitive performance in males

Cognitive decline brought on by aging is a precursor to dementias like Alzheimer’s and can have a significant impact on a person’s ability to carry out essential daily tasks.

16 Sep 2022

Characterizing the transcription profile of microglia in a mouse model

Researchers from Tohoku University have now shown that the consolidation and extinction of contextual fear conditioning alter the microglial genes connected to the synapse—structures that permit neurons to communicate with one another.

13 Sep 2022

Spatial transcriptomic data highlights the features of the axolotl brain

The first spatiotemporal cellular atlas of axolotl (Ambystoma mexicanum) brain growth and regeneration, created by a multi-institute research team under the direction of BGI-Research, reveals how brain damage may recover itself.

8 Sep 2022

Scientists discover latent stem cells that respond to injury in the central nervous system of mice

Scientists at the Francis Crick Institute have identified a group of latent stem cells that respond to injury in the central nervous system of mice. If a similar type of cell exists in humans, they could offer a new therapeutic approach to treat brain and spinal cord injuries.

23 Aug 2022

Researchers capture images of antibodies attacking neuron receptors using Cryo-Electron Microscopy Facility

Scientists have for the first time photographed an autoantibody coupled to a receptor on the surface of a nerve cell using the Cryo-Electron Microscopy Facility at UT Southwestern.

14 Jul 2022

Researchers discover a unique origin of severe pediatric brain cancer

A new cause of severe childhood brain cancer has been discovered by scientists.

25 Apr 2022

New technique for better visualizing the CNS fibroblasts

The central nervous system (CNS) consists of several types of cells having varied specialized functions.

7 Apr 2022

Study sheds light on genetic causes of Alzheimer’s disease and other dementias

If we want to enhance our knowledge and treatment of Alzheimer’s disease, we need to identify genetic risk factors.

7 Apr 2022

New project receives over $700,000 to study about CHARGE syndrome

CHARGE syndrome, which affects approximately one in 10,000 newborns worldwide, is associated with neurological and behavioral conditions like intellectual disability, attention deficit disorder, convulsions, and autism.

1 Apr 2022

Researchers determine major protein complexes that cause ribosome production

Scientists at UT Southwestern have discovered a four-protein complex that seems to play a significant function in the formation of ribosomes, which serve as protein factories for cells, as well as a surprise role in neurodevelopmental diseases.

1 Apr 2022

Researchers develop an antibody as a tool for opening the blood-brain barrier

The brain is composed of billions of neurons-; vulnerable cells that require a protective environment to function properly.

17 Mar 2022

Insight into oligodendrocyte cells could lead to new treatments for neurodegenerative diseases

New research may help scientists locate immature cells in the central nervous system that could shed light on the causes of neurodegenerative diseases like multiple sclerosis-;and autoimmune disease that affects the brain and nervous system-;and allow for the development of better therapeutic treatments.

14 Mar 2022

Oligodendrocyte plays major role in the development of multiple sclerosis, says study

A team of international researchers revealed that oligodendrocytes, a kind of central nervous system cell, may play a different function in the progression of MS.

2 Feb 2022

Cancer drug effective against Alzheimer’s disease, says research

According to recent research carried out by researchers from the Weill Cornell Medicine, a gene mutation associated with Alzheimer’s disease changes a signaling pathway in specific immune cells of individuals with the disease.

7 Dec 2021

Glial cells in the heart play critical role in cardiac development and function

Glial cells in the heart help regulate heart rate and rhythm, and drive its development in the embryo, according to a new study publishing November 18th in the open-access journal PLOS Biology by Nina Kikel-Coury, Cody Smith and colleagues at the University of Notre Dame.

19 Nov 2021

Genomic changes in advanced tumors reveal interactions with treatment

A novel way to look at cancer treatment resistance offers the possibility for identifying genetic mechanisms involved and alternative treatment approaches.

17 Nov 2021

Tough protein connects directly with neurons to cause damaging inflammatory reaction in the brain

Neuroinflammatory diseases, including Alzheimer's disease and traumatic brain injury, have been linked to deposits of a tough protein known as fibrin, derived from the blood clotting factor fibrinogen.

9 Nov 2021

CHOP-led network aims to unlock the genetic mysteries behind pediatric brain tumors

Unlocking the genetic mysteries behind pediatric brain tumors is at the heart of the mission of the Center for Data Driven Discovery in Biomedicine (D3b) at Children's Hospital of Philadelphia.

3 Nov 2021

Monoclonal antibodies mitigate inflammatory consequences of SARS-CoV-2 exposure in macaques

Monoclonal antibodies protected aged, diabetic rhesus macaque monkeys from disease due to SARS-CoV-2 and reduced signs of inflammation, including in cerebrospinal fluid, according to a new study from researchers at the University of California, Davis.

From The University of California, Davis 2 Nov 2021

Delta opioid receptor agonists modulate immune responses to ameliorate colonic inflammation

Opioids are a class of substances that control sensations such as pain and emotions in animals. While plant-derived opioid narcotics such as morphine are the most well-recognized, other opioid molecules like endorphins can also be synthesized by the body or artificially developed in laboratories.

From Tokyo University of Science 1 Oct 2021

Central Nervous System News and Research

Interactions between plasma miRNAs and cognitive performance in males

Characterizing the transcription profile of microglia in a mouse model

Spatial transcriptomic data highlights the features of the axolotl brain

Scientists discover latent stem cells that respond to injury in the central nervous system of mice

Researchers capture images of antibodies attacking neuron receptors using Cryo-Electron Microscopy Facility

Researchers discover a unique origin of severe pediatric brain cancer

New technique for better visualizing the CNS fibroblasts

Study sheds light on genetic causes of Alzheimer’s disease and other dementias

New project receives over $700,000 to study about CHARGE syndrome

Researchers determine major protein complexes that cause ribosome production

Researchers develop an antibody as a tool for opening the blood-brain barrier

Insight into oligodendrocyte cells could lead to new treatments for neurodegenerative diseases

Oligodendrocyte plays major role in the development of multiple sclerosis, says study

Cancer drug effective against Alzheimer’s disease, says research

Glial cells in the heart play critical role in cardiac development and function

Genomic changes in advanced tumors reveal interactions with treatment

Tough protein connects directly with neurons to cause damaging inflammatory reaction in the brain

CHOP-led network aims to unlock the genetic mysteries behind pediatric brain tumors

Monoclonal antibodies mitigate inflammatory consequences of SARS-CoV-2 exposure in macaques

Delta opioid receptor agonists modulate immune responses to ameliorate colonic inflammation

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