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DNA origami helps track gene-editing processes

The genetic scissors, known as CRISPR/Cas9, the finding that received a Nobel Prize in Chemistry, occasionally cut in places that they are not intended to target.

24 Feb 2021

Advanced explainable AI to solve regulatory instructions encoded in DNA

Researchers at the Stowers Institute for Medical Research, in collaboration with colleagues at Stanford University and Technical University of Munich have developed advanced explainable artificial intelligence (AI) in a technical tour de force to decipher regulatory instructions encoded in DNA.

19 Feb 2021

Unusual DNA folding leads to higher mutation rates

DNA sequences that can fold into shapes other than the classic double helix tend to have higher mutation rates than other regions in the human genome.

From Penn State University 10 Feb 2021

Scientists discover the origin of rare genetic syndrome

Improvements in DNA sequencing have revealed a rare syndrome triggered by changes in the SATB1gene.

29 Jan 2021

Repair proteins can help healthy cells to avoid damage during cancer therapy

A key way radiation therapy and chemotherapy work is by making highly lethal double-strand breaks in the DNA of cancer cells.

10 Dec 2020

Scientists propose a simple model for gene regulation in higher organisms

Although the DNA and its double-helix are some of the most familiar molecules of our time, our knowledge of how cells control what genes they want to express still is rather limited. In order to create, for example, an enzyme, the information that's inscribed in our DNA about this enzyme needs to be transcribed and translated.

4 Dec 2020

Researchers determine 3D structures of RNA hybridization with artificial nucleic acids

As medical research progresses, traditional treatment protocols are being rapidly exhausted. New approaches to treat diseases that do not respond to conventional drugs are the need of the hour.

4 Dec 2020

New study refutes a major cellular process in bacteria

Despite explanations in textbooks, a new study has discovered and elucidated a cellular process that has continued to remain a mystery for researchers.

30 Nov 2020

MIT chemists determine molecular structure of SARS-CoV-2 protein

MIT chemists have determined the molecular structure of a protein found in the SARS-CoV-2 virus. This protein, called the envelope protein E, forms a cation-selective channel and plays a key role in the virus's ability to replicate itself and stimulate the host cell's inflammation response.

From Massachusetts Institute of Technology (MIT) 16 Nov 2020

Exposure to air pollution during fetal period may contribute to higher blood pressure

Exposure to an urban environment characterised by high levels of air pollution and noise in areas with a high building density during the foetal period and in early childhood may contribute to higher blood pressure.

16 Nov 2020

Researchers develop a new method for siRNA stabilization

In the gene controlling mechanism, known as RNA interference, the expression of particular genes is downregulated by siRNAs or endogenic microRNAs.

19 Oct 2020

Scientists identify heart cells responsible for repairing damaged heart after infarction

A global study has discovered the heart cells responsible for repairing the damage induced to this vital organ following infarction.

15 Oct 2020

Scientists uncover new parvovirus strategy for reaching the cell nucleus

Researchers at the Institut national de la recherche scientifique, in collaboration with American scientists, have uncovered a new parvovirus strategy for reaching the cell nucleus which is their site of replication.

25 Sep 2020

Study may lead to better treatments for cancer and developmental syndromes

The most rudimentary activity of a living thing is to change one copy of its genome into two copies, creating one cell into two.

18 Sep 2020

Study offers promising data for improved treatments for cardiac disease

A group of researchers have recently published an article that provides promising data for enhanced therapeutic treatments for cardiac disease.

20 Aug 2020

Improving the accuracy of DNA melt curve

DNA is not only the blueprint of life, it has become the backbone for making tiny structures that can be inserted into the human body to diagnose and treat disease.

20 Aug 2020

New study may offer a novel, potential target for treating breast cancer

According to researchers, G-quadruplexes have been demonstrated to play a crucial role in specific types of breast cancer for the first time.

5 Aug 2020

Community-based genetic screening has potential to identify individuals at risk for inherited diseases

In a new study published today in the journal Nature Medicine, researchers behind the Healthy Nevada Project® suggest that community-based genetic screening has the potential to efficiently identify individuals who may be at increased risk for three common inherited genetic conditions known to cause several forms of cancer and increased risk for heart disease or stroke.

28 Jul 2020

Researchers image the formation of four-stranded DNA in living human cells

The development of four-stranded DNA has been monitored in the living cells of human beings, enabling researchers to observe its potential role in cancer.

21 Jul 2020