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Cryo-EM Imaging Unveils Similar Protein Structures in Alzheimer's and Down Syndrome

More than 90% of people with Down syndrome, the most common chromosomal disorder in humans and the most frequent genetic cause of intellectual disability, are diagnosed with Alzheimer's disease by ages 55-60.

30 Mar 2024

Nanoparticle-Based Therapy Shows Promise in Eradicating Tumors

A nanoparticle-based therapy developed by UT Southwestern Medical Center scientists stimulated an immune pathway that eradicated tumors in mouse models of various cancer types.

28 Mar 2024

To Bolster Global Efforts in Combating Antibiotic-Resistant Bacteria KFSH&RC Scientists Discover New Bacteria Species: Riyadhensis

In a ground-breaking development, scientists at King Faisal Specialist Hospital and Research Centre (KFSH&RC) have identified a new species of bacteria, referred to as "Stenotrophomonas Riyadhensis" through the application of whole-genome sequencing (WGS) technology.

27 Mar 2024

Federal Regulation Urged for Direct-to-Consumer Microbiome Tests

Scientific research has linked a person's microbiome to everything from gut and mental health to immunity and predisposition to cancer.

25 Mar 2024

Groundbreaking Physics Study Offers Insights Into Self-Organization of Biological Particles

Erin McCarthy '23, physics summa cum laude, is a rarity among young scientists. As an undergraduate researcher in Syracuse University's College of Arts & Sciences' Department of Physics, she guided a study that appeared in March 2024 in Physical Review Letters. It is the most-cited physics letters journal and the eighth-most cited journal in science overall.

25 Mar 2024

NIH Researchers Map Vulnerable Sites on Epstein-Barr Virus gp42 Protein

Studies of interactions between two lab-generated monoclonal antibodies (mAbs) and an essential Epstein-Barr virus (EBV) protein have uncovered targets that could be exploited in designing treatments and vaccines for this extremely common virus.

13 Mar 2024

Biological Glue Provides Clues About Cardiovascular Diseases

University of Virginia School of Medicine scientists have found important answers about strokes, heart attacks and cardiovascular diseases by probing the biological glue our bodies create to protect us from those deadly dangers.

12 Mar 2024

The Role of Vitamin A in the Pathogenesis of Psychiatric Disorders

A group of researchers in Newcastle has been investigating the part that vitamin A plays in the pathogenesis of psychiatric disorders.

12 Mar 2024

Transition to Laser-Based 3D Bioprinting: Stride Towards Addressing Organ Shortage

Recent advancements in laser technology are leading to groundbreaking developments in the medical field, from improved treatment of cardiovascular diseases to higher-precision manufacturing of medical devices.

7 Mar 2024

‘Like a PCR Lab in Your Pocket': New Test Strips Raise Game in Gene-Based Diagnostics

Biosensing technology developed by UNSW engineers has made it possible to make portable RAT tests just as accurate as PCR tests carried out in a lab.

7 Mar 2024

Grasping the Concept of Mendelian Randomization

Mendelian randomization, a key method in medical research, aids in determining whether certain factors actually cause disease.

4 Mar 2024

Neuroscientists Uncover Significance of Glial Cells in Brain Communication

Neuroscientists at Fred Hutchinson Cancer Center have found that an often-overlooked type of brain cell called glia has more of a role in brain function than previously thought.

29 Feb 2024

Scientists Develop First Full Model of Early Human Central Nervous System with Stem Cells

The first stem cell culture method that produces a full model of the early stages of the human central nervous system has been developed by a team of engineers and biologists at the University of Michigan, the Weizmann Institute of Science, and the University of Pennsylvania.

27 Feb 2024

Mechanism of Cancer Drug Targeting Tumor Suppressor Genes Unveiled

Researchers have revealed the mechanism of a drug shown to be effective in treating certain types of cancer, which targets a protein modification silencing the expression of multiple tumor suppressor genes.

22 Feb 2024

Relation Between Faulty DNA Disposal System and Inflammation

The path from mitochondrial stress to leaking endosomes to immune system initiation in mouse cells is outlined by Salk scientists, providing new therapeutic targets to potentially reduce inflammation in aging and disease.

12 Feb 2024

Immune System Surprise: "Junk Cells" Show Ability to Fight Malaria

Researchers from The Australian National University (ANU) have discovered a previously unknown ability of a group of immune system cells, known as Atypical B cells (ABCs), to fight infectious diseases such as malaria.

9 Feb 2024

‘Mini-Placentas’ Help Scientists Study the Causes of Pre-eclampsia and Pregnancy Disorders

Scientists have grown ‘mini-placentas’ in the lab and used them to see how the placenta develops and interacts with the inner lining of the womb – findings that could help scientists better understand and, in future, potentially treat pre-eclampsia.

17 Jan 2024

Messenger RNA Therapy Could be Used to Correct Rare Liver Genetic Disease

By exploiting the technology used in Covid-19 vaccines, a team led by UCL, King's College London and Moderna scientists has created an effective therapy for a rare disease, in a study in mice, demonstrating the technology's potential therapeutic use in people.

16 Jan 2024

Epigenetic Key Unlocks Treatment Path for Endocrine-Resistant Breast Cancer

Endocrine resistance – a major cause of breast cancer deaths – can be underpinned by an epigenetic change called DNA methylation, researchers at the Garvan Institute of Medical Research have discovered.

10 Jan 2024

SPACEL: A Powerful AI Toolkit for Unveiling the 3D Secrets of Tissues

Spatial transcriptomics (ST) technologies are applied in biology and medical research for its ability to detect the spatial distribution of transcriptome in histological tissue slices.

3 Jan 2024