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Specialized Proliferative Cells Contribute to Epithelial Regeneration in Jellyfish

At about the size of a pinkie nail, the jellyfish species Cladonema can regenerate an amputated tentacle in two to three days -; but how? Regenerating functional tissue across species, including salamanders and insects, relies on the ability to form a blastema, a clump of undifferentiated cells that can repair damage and grow into the missing appendage.

26 Dec 2023

Scientists Unravel the Mystery of Parkinson's Disease With 3D Protein Structures

Scientists at St. Jude Children's Research Hospital revealed the complex structure of two Parkinson's disease-related proteins, both of which are implicated in late-onset cases.

26 Dec 2023

The Adrenaline Puzzle Solved: Scientists Untangle Key Cell Receptor's Inner Workings

Through an international collaboration, scientists at St. Jude Children's Research Hospital leveraged data science, pharmacology and structural information to conduct an atomic-level investigation into how each amino acid in the receptor that binds adrenaline contributes to receptor activity in the presence of this natural ligand.

26 Dec 2023

Cracking the Code of the Cytoplasm: How Cells Organize Protein Production

Back in 2018, the lab of Christine Mayr, MD, PhD, at Memorial Sloan Kettering Cancer Center (MSK) introduced the world to a key cellular component that had been hiding in plain sight.

22 Dec 2023

Researchers Redesign the Future of mRNA Therapeutics

Scientists have unearthed that errors in the interpretation of therapeutic mRNA by the cell’s decoding apparatus can incite an inadvertent immune reaction within the body.

7 Dec 2023

Pancreatic Nerve Zaps Restore Insulin Production and Reverse Diabetes in Mice

Insulin is a hormone that decreases blood glucose levels. The only cells that produce insulin are pancreatic beta cells (β-cells), and a decrease in these cells is a major cause of diabetes.

5 Dec 2023

Researchers Redesign Future mRNA Therapeutics to Prevent Potentially Harmful Immune Responses

Researchers have discovered that misreading of therapeutic mRNAs by the cell’s decoding machinery can cause an unintended immune response in the body.

5 Dec 2023

"Wake" Slow Waves may Decrease the Impact of Epileptic Spikes on Brain Activity

Slow waves that usually only occur in the brain during sleep are also present during wakefulness in people with epilepsy and may protect against increased brain excitability associated with the condition, finds a new study led by researchers at UCL.

30 Nov 2023

Nutrient Derived From Meat and Dairy Enhances Cancer Killing Ability of Immune Cells

Trans-vaccenic acid (TVA), a long-chain fatty acid found in meat and dairy products from grazing animals such as cows and sheep, improves the ability of CD8+ T cells to infiltrate tumors and kill cancer cells, according to a new study by researchers from the University of Chicago.

27 Nov 2023

How 3D-Printed Organs Could Reduce Use of Animal Testing in Medical Research

In the realm of scientific research, particularly in the medical and pharmaceutical sectors, animal testing has been a prevalent method.

22 Nov 2023

SMART Researchers Pioneer Novel Microfluidic Method to Optimize Bone Marrow Stem Cell Extraction for Advanced Cell Therapies

Researchers from the Critical Analytics for Manufacturing Personalized-Medicine (CAMP) Interdisciplinary Research Group (IRG) of Singapore-MIT Alliance for Research and Technology (SMART), MIT’s research enterprise in Singapore, in collaboration with the Agency for Science, Technology and Research (A*STAR) Bioprocessing Technology Institute (BTI) and National University Health System (NUHS), have developed a groundbreaking technology.

22 Nov 2023

Early Life Host Control Shapes Sea Anemone Microbiome Composition

The microbiome, denoting the harmonious assembly of microorganisms within a host, is essential for the optimal operation of plants and animals, including humans.

21 Nov 2023

Artificial System Develops Key Characteristics Similar to Human Brains Under Physical Constraints

Cambridge scientists have shown that placing physical constraints on an artificially-intelligent system – in much the same way that the human brain has to develop and operate within physical and biological constraints – allows it to develop features of the brains of complex organisms in order to solve tasks.

21 Nov 2023

Dissecting the Mechanisms Behind Selective Genomic Editing

A new study is in progress to unravel a fascinating biological mystery of how certain animals can naturally eliminate more than half of their genetic information during embryonic development.

10 Nov 2023

GOV UK Introduces New 'AI Life Sciences' Fund - IEEE Comments

Last week, the UK Government announced it will be launching the AI Life Sciences Accelerator Mission. Approximately £100 million will be allocated to help drive AI innovation and tackle the UK’s biggest healthcare challenges

9 Nov 2023

New Study Sheds Light on Evolution of Sex Differences in Animals

Researchers at the Francis Crick Institute and Heidelberg University in Germany have shown that sex differences in animals vary dramatically across species, organs and developmental stages, and evolve quickly at the gene level but slowly at the cell type level.

3 Nov 2023

New £100 Million Fund to Capitalise on AI’s Game-Changing Potential in Life Sciences and Healthcare

A new mission announced by the Prime Minister will accelerate the use of AI in life sciences to tackle the biggest health challenges of our generation.

30 Oct 2023

Unlocking the Potential of Lab-Made Hydrogel for Tissue Growth and Medical Applications

A recently developed laboratory-created material imitates human tissue and has the potential to decrease or substitute for the utilization of animal-derived components in biomedical studies.

24 Oct 2023

Hair Follicle Regression may be Driven by Cell-to-Cell Apoptosis

A new research paper was published in Oncotarget's Volume 14 on October 19, 2023, entitled, "Apoptotic cells may drive cell death in hair follicles during their regression cycle."

24 Oct 2023

New Microscopy Technique Reveals Unprecedented Details of Amyloid Plaques in Alzheimer's Disease

Researchers from the Universitat Autònoma de Barcelona (UAB), the Karolinska Institute (KI), and the biotechnology company BioArctic, both in Sweden, have combined STED microscopy, a technology that allows super-resolution visualization, and a new antibody recently created to observe the amyloidogenic aggregates characteristic of Alzheimer's disease.

12 Oct 2023

Medical Research News and Research

Specialized Proliferative Cells Contribute to Epithelial Regeneration in Jellyfish

Scientists Unravel the Mystery of Parkinson's Disease With 3D Protein Structures

The Adrenaline Puzzle Solved: Scientists Untangle Key Cell Receptor's Inner Workings

Cracking the Code of the Cytoplasm: How Cells Organize Protein Production

Researchers Redesign the Future of mRNA Therapeutics

Pancreatic Nerve Zaps Restore Insulin Production and Reverse Diabetes in Mice

Researchers Redesign Future mRNA Therapeutics to Prevent Potentially Harmful Immune Responses

"Wake" Slow Waves may Decrease the Impact of Epileptic Spikes on Brain Activity

Nutrient Derived From Meat and Dairy Enhances Cancer Killing Ability of Immune Cells

How 3D-Printed Organs Could Reduce Use of Animal Testing in Medical Research

SMART Researchers Pioneer Novel Microfluidic Method to Optimize Bone Marrow Stem Cell Extraction for Advanced Cell Therapies

Early Life Host Control Shapes Sea Anemone Microbiome Composition

Artificial System Develops Key Characteristics Similar to Human Brains Under Physical Constraints

Dissecting the Mechanisms Behind Selective Genomic Editing

GOV UK Introduces New 'AI Life Sciences' Fund - IEEE Comments

New Study Sheds Light on Evolution of Sex Differences in Animals

New £100 Million Fund to Capitalise on AI’s Game-Changing Potential in Life Sciences and Healthcare

Unlocking the Potential of Lab-Made Hydrogel for Tissue Growth and Medical Applications

Hair Follicle Regression may be Driven by Cell-to-Cell Apoptosis

New Microscopy Technique Reveals Unprecedented Details of Amyloid Plaques in Alzheimer's Disease

Driving Support for Pharmaceutical Testing Through Continuous Innovation

From Memory to Metaplasticity: Unraveling the Brain's Secrets

Revolutionizing Mass Spectrometry: A Deep Dive into Plasmion’s SICRIT® Technology

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