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New Mechanism for Selective Host-Microbe Communication in the Gut

The study reveals how APOL9 selectively binds to gut bacteria, enhancing immune responses and maintaining intestinal health through microbial communication.

15 May 2025

AI Designs Synthetic DNA to Control Gene Expression in Mammalian Cells

A study published today in the journal Cell marks the first reported instance of generative AI designing synthetic molecules that can successfully control gene expression in healthy mammalian cells.

10 May 2025

Mammal’s Lifespans Linked to Brain Size and Immune System Function, Says New Study

Why do cats generally live longer than dogs? New research suggests that longer livespans of mammals like cats could be linked to their bigger brains and more complex immune systems.

9 May 2025

Genes Influence When Babies Start Walking, Study Finds

Researchers examined over 70,000 infants’ genomic information in the first research of its kind. Eleven genetic markers were found to influence when babies begin to walk, providing a number of possibilities for more in-depth biological research.

8 May 2025

Study Unlocks Molecular Mechanisms Behind Tea Plant Defenses

Plants face constant threats from herbivores, prompting complex defense mechanisms. While grasses like rice and Arabidopsis have well-studied defense systems, woody plants like tea remain poorly understood.

7 May 2025

Restoring Alpha-Synuclein to Support Synaptic Function and Neurotransmission

A new study reveals how restoring α-synuclein levels can help preserve synaptic vesicle composition and function, offering therapeutic insights for Parkinson’s and other neurodegenerative diseases.

7 May 2025

Role of LADs and Epigenetic Pathways in Nuclear Architecture During Early Mouse Embryo Development

A new study in Cell reveals that lamina-associated domains (LADs) in early mouse embryos are shaped by dynamic epigenetic pathways, highlighting how histone modifications and chromatin structure guide nuclear architecture during development.

6 May 2025

Dr. Jeremy Poschmann’s data-driven approach to immune profiling and translational science

Dr. Jeremy Poschmann discusses data-driven approaches in genomics, revealing how immune profiling can predict disease risk and improve patient outcomes.

1 May 2025

Genetic Diversity in Wild Rice Offers Clues for Crop Improvement

A new study, seen in Nature Genetics and led by researchers at King Abdullah University of Science and Technology (KAUST; Saudi Arabia) and Wageningen University & Research (the Netherlands), provides new insights on rice evolution, showing how the DNA of this valuable crop has changed across species.

29 Apr 2025

New Pangenome Analysis Uncovers Genetic Key to Larger Peanut Yields

Researchers from Australia and China have identified crucial structural variations that determine seed size and weight in peanuts, paving the way for the development of higher-yielding crop varieties.

29 Apr 2025

AI-Powered Protein Engineering for Precise and Scalable Gene Therapy

Genome editing has progressed rapidly, showing promising outcomes for the treatment of genetic disorders, yet there remains potential for enhancement.

23 Apr 2025

DNA Organization Offers Clues for Advancing Stem Cell Therapy

Scientists at the University of California, Riverside, have discovered how adult stem cells retain their regenerative power. The researchers demonstrate in a paper published in the journal Genes & Development that these cells rely on a group of helper proteins called histone chaperones — organizers or guides known to help package our two-meter-long genome when cells need to divide or switch on specific genes.

22 Apr 2025

Cyber Vulnerabilities in Next-Gen DNA Sequencing

Next-generation DNA sequencing (NGS), a technology driving personalized medicine, cancer diagnosis, infectious disease tracking, and genetic research, is increasingly vulnerable to cyberattacks.

17 Apr 2025

Researchers Develop Quantum-AI Platform to Predict Antimicrobial Resistance in Salmonella

SARPLLM leverages large language modeling and quantum algorithms to predict Salmonella AMR, offering robust analysis and user-friendly data visualization tools.

17 Apr 2025

Inherited Genes Play Key Role in Cancer Development

A groundbreaking study has revealed how inherited genetic abnormalities, known as germline variants, play a vital role in the progression of cancer.

16 Apr 2025

Tumor Recurrence Prediction from Multi-Omics Information by Deep Learning

MULGONET combines deep learning and multi-omics analysis to predict tumor recurrence, addressing interpretability and enhancing cancer prognosis understanding.

16 Apr 2025

Crucial Details in DNA Repair Processes

Researchers at the University of Birmingham have discovered answers that offer detail to explain two distinct DNA repair pathways that have long been debated.

15 Apr 2025

How P. syringae Outsmarts Amoeba with Chemical Surveillance and Strikes

Pseudomonas syringae's chemical sensing system allows it to kill amoeba predators, showcasing its evolutionary strategies for survival and plant infection.

14 Apr 2025

Complete Reference Genomes Unlocked for Six Ape Species

Comprehensive reference genomes have now been assembled for six ape species: siamang (a Southeast Asian gibbon), Sumatran orangutan, Bornean orangutan, gorilla, bonobo and chimpanzee.

12 Apr 2025

New Genetic Insights From Long Read Sequencing in a Teen With Complex Psychiatric Conditions

In a manuscript published today in the American Journal of Psychiatry titled Long-Read Genome Sequencing in Clinical Psychiatry: RFX3 Haploinsufficiency in a Hospitalized Adolescent With Autism, Intellectual Disability, and Behavioral Decompensation, authors describe how they leveraged long-read genomic sequencing (LRS) to make a genetic diagnosis in a17-year-old male with autism spectrum disorder, intellectual disability, and acute behavioral decompensation that would not have been possible by standard methods.

12 Apr 2025