DNA Damage News and Research

RSS

Optimizing Laser Pulse Energy for Deep-Brain Imaging Without Tissue Damage

As light travels deeper into the brain, it scatters. Three-photon microscopy, the current state of the art, reduces the resulting background fluorescence and can, in principle, image much deeper than earlier techniques-but to do that, it uses average laser power limits that cause overheating and damage living tissue.

29 Oct 2026

PARP1 Disassembles Nucleosomes to Facilitate Essential DNA Damage Repair

When DNA is damaged, cellular processes respond and repair the DNA. Inhibiting DNA damage repair can be therapeutically beneficial in cancers with genetic vulnerabilities related to DNA damage response.

26 Oct 2026

Cryo-EM Snapshots Capture Multi-Stage Structural Transitions During DNA Recombination

Bacteriophages, or viruses that infect bacteria, have a fiendishly simple purpose in life: attach to a bacterial cell, inject their DNA, and then use the host's genetic machinery to reproduce. In doing so, they may have evolved some of the most efficient gene editing tools ever seen in nature.

15 Oct 2026

Single-Nucleosome Imaging Tracks Chromatin Movement in Asynchronous Human Cells

Human genomic DNA is wrapped around core histone proteins to form nucleosomes, the fundamental units of chromatin.

15 Oct 2026

Aldabra Giant Tortoise Genome Provides Evolutionary Blueprint for Cellular Resilience

Researchers studying a giant tortoise named Jonathan say it's not just good genes, but lack of genetic wear and tear that have kept him going for nearly two centuries.

8 Oct 2026

USP15 Protein May Help Ovarian Cancer Resist Chemotherapy

Blocking USP15 in ovarian cancer cells disrupts growth and enhances chemotherapy sensitivity, revealing a potential target for overcoming treatment resistance.

1 Oct 2026

Invasive E. coli Strains Promote Host Invasion of Harmless Strains

When scientists assess how dangerous a bacterium is, the first question often seems simple: can it be stopped or killed?

1 Oct 2026

Researchers Simulate Microgravity to Isolate Gravity's Impact on Human Chromatin

The Human Genome Project was launched in 1990, preceded by decades of breakthroughs in genetics. It eventually gave us a sequence of the human genome.

24 Sep 2026

Tumor Suppressor Pathways Remain Intact but Hyperactive During Progressive Tissue Aging

A new review was published in Volume 18 of Aging on August 31, 2026, titled "The guardian paradox: DNA damage response overactivation as an integrative driver of aging – a tumor suppressor–negative regulator framework."

22 Sep 2026

Researchers Analyze Somatic DNA Integrity across Complex Longevity Pathways

A new review was published in Volume 18 of Aging on August 26, 2026, titled "Assessing mechanisms and evidence of a causal role for cellular senescence and somatic mutations in aging."

15 Sep 2026

Advanced Gene Editing Provides Essential Tool for Studying Early Human Embryonic Development

A study by researchers at Columbia University Vagelos College of Physicians and Surgeons has found that new cutting-edge techniques can accurately edit genes in human embryos-giving scientists indispensable tools for understanding normal human development-but has also uncovered important risks that currently preclude the use of the techniques in the clinic.

10 Sep 2026

Human Embryos Repair Single-Strand DNA Damage Reliably but Fail at Double-Strand Breaks

Although DNA repair is one of the fundamental processes required for normal human embryonic development, little has been known about how it operates during the earliest stages of development.

10 Sep 2026

Study Reveals Hidden Mutational Process in Colorectal Cancer

The discovery of SBS111 in colorectal cancer offers new perspectives on mutational processes and DNA repair, emphasizing its significance in tumor biology.

3 Sep 2026

Scientists Find Cancer Gene Forcing Zombie Cells to Cause Aging

In a tale of identities as divergent as "The Prince and the Pauper," a well-known cancer-causing gene also influences cells in a zombie-like state meant to prevent cancer.

31 Aug 2026

Researchers Outline Quantitative Principles of Cell Signaling Time Codes

For decades, biologists assumed that cells transmit instructions mainly through the concentration of signaling molecules - the higher the level, the stronger the response.

27 Aug 2026

New Computational Tool Estimates Cell Age by Analyzing Gene Activity Patterns

Scientists at Karolinska Institutet and Stockholm University have created an innovative tool that determines cellular biological age through gene activity analysis.

24 Aug 2026

Study Redefines How Cancer Cells Enter Senescence

Stopping tumor growth is only half the battle. Rather than kill tumor cells, many cancer therapies can only push them into cellular senescence, a state in which cells stop dividing but do not die. These "undead" cells will continue to release signals that reshape the tumor environment.

21 Aug 2026

DNA Damage News and Research

Optimizing Laser Pulse Energy for Deep-Brain Imaging Without Tissue Damage

PARP1 Disassembles Nucleosomes to Facilitate Essential DNA Damage Repair

Cryo-EM Snapshots Capture Multi-Stage Structural Transitions During DNA Recombination

Single-Nucleosome Imaging Tracks Chromatin Movement in Asynchronous Human Cells

Aldabra Giant Tortoise Genome Provides Evolutionary Blueprint for Cellular Resilience

USP15 Protein May Help Ovarian Cancer Resist Chemotherapy

Invasive E. coli Strains Promote Host Invasion of Harmless Strains

Researchers Simulate Microgravity to Isolate Gravity's Impact on Human Chromatin

Tumor Suppressor Pathways Remain Intact but Hyperactive During Progressive Tissue Aging

Researchers Analyze Somatic DNA Integrity across Complex Longevity Pathways

Advanced Gene Editing Provides Essential Tool for Studying Early Human Embryonic Development

Human Embryos Repair Single-Strand DNA Damage Reliably but Fail at Double-Strand Breaks

Study Reveals Hidden Mutational Process in Colorectal Cancer

Scientists Find Cancer Gene Forcing Zombie Cells to Cause Aging

Researchers Outline Quantitative Principles of Cell Signaling Time Codes

New Computational Tool Estimates Cell Age by Analyzing Gene Activity Patterns

Study Redefines How Cancer Cells Enter Senescence

Researchers Reveal Overlooked Colorectal Cancer DNA Repair Breakdown Fingerprint

Stable RNA Structures Revolutionize Quality of Life in Oncology Care

Researchers Track Genetic Mutation Clues Behind Accelerated Aging Vascular Decline

The Future of Vision Restoration With ReVision Implant

How a Single List Is Changing Visibility for Women in Science

How Avatar Medical's 3D Technology Is Transforming How We Visualize the Human Body

Editorial Focus eBook - Biopharmaceuticals (2nd edition)

Improving Cell Culture Efficiency with Image-Guided Automation

Improving Scalability in Organoid Research

Cosmetic Formulation and Manufacturing

Latest in Genomics