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Gut-Derived Neutral Ceramidase Regulates MASH Through Microbial and Epithelial Signaling

Metabolic dysfunction-associated steatohepatitis (MASH) is often viewed through the lens of hepatic lipid accumulation, inflammation and fibrosis.

30 Sep 2026

Chronic Inflammation Linked to Heart Changes and Risks

Chronic inflammation, indicated by GlycA levels, has been linked to heart changes and increased cardiovascular risk, highlighting genetic and environmental interactions.

25 Sep 2026

Engineered E. coli Strains Validate Putrescine Uptake and Systemic Host Conversion

Gut microbiota influences multiple aspects of host physiology, including metabolic and immune functions. Many metabolites produced by gut bacteria can cross the intestinal epithelium (which the bacteria may not be able to cross) and enter host tissues, providing a pathway through which microbial activity can influence host physiology.

25 Sep 2026

Cancer Cells Hijack Embryonic Repair Mechanisms to Seed Liver Metastases

Most colon cancer deaths are caused by the spread of tumor cells beyond the colon, usually to the liver. In a new study, MIT biologists identified a cellular pathway necessary for colorectal cancer metastasis.

25 Sep 2026

Strength Training Induces Fat Breakdown in Obese Mice Without Weight Loss

Just seven days of strength training increased visceral fat burning in obese mice, even before any weight loss could be seen on a scale. In an experiment conducted at the State University of Campinas (UNICAMP), researchers observed that a short period of strength training activated mechanisms involved in fat breakdown, reduced fat cell size, and decreased fat around the animals' intestines.

23 Sep 2026

Restoring Gut Indole Levels Reduces Campylobacter Infection in Mouse Models

What if something produced naturally by your gut bacteria could help fight a dangerous foodborne pathogen?

17 Sep 2026

Scientists Identify Molecular Mechanism Behind Persistent Obesity and Weight Relapse

Two enduring biological mysteries have remained unsolved for decades: why almost everyone who loses weight gains it back, no matter how they lost it, and why obesity passes from mother to child at rates that diet and environment cannot explain. Now, scientists from Harrington Discovery Institute at University Hospitals and Case Western Reserve University have identified why.

11 Sep 2026

Elusive Archaea Act as Flexitarians in Marine Sponge Symbiosis

Symbiotic ammonia-oxidizing archaea in marine sponges are not strict specialists, but true "flexitarians": A team led by microbiologists Bettina Glasl and Katharina Kitzinger from the University of Vienna, in collaboration with partners from Australia, has shown that these microbes dine not only on ammonia but also on amino acids such as valine, leucine, and isoleucine - and presumably do that to communicate with their animal host.

7 Sep 2026

Ancient DNA Reveals Famous Extinct Feline Was Actually Fish Eating Puma

A new study led by researchers at the University of California, Santa Cruz, has overturned decades of assumptions about Miracinonyx trumani, the extinct predator popularly known as the American cheetah.

7 Sep 2026

New Research: Greenland’s Smallest Animals are Changing with the Climate

Researchers at Aalborg University, Denmark, have spent several years studying insects in Greenland.

3 Sep 2026

Targeting EFHD1 Protein Prevents Severe Obesity-Related Metabolic Liver Damage

Obesity-related metabolic liver disease affects hundreds of millions of people worldwide, but only some fraction of those livers develop scarring, become inflamed, and eventually fail.

2 Sep 2026

Research Identifies Essential Energy Sources for Developing Carnivorous Larval Fish

Lipids are essential for fish because they supply energy, support cell structure, and help carry fat-soluble nutrients. This is especially important in carnivorous fish, which use carbohydrates less efficiently than many other animals.

25 Aug 2026

Transition From Milk to Solid Food Shapes Immune System Development

The early period of life is a critical phase in which the immune system must learn to tolerate harmless environmental stimuli, such as food and microbes that normally live in and on the body, while remaining vigilant against harmful substances and pathogens.

12 Aug 2026

Arginine Supplementation Enhances Immune Defense Against Tumors and Viruses

The amino acid arginine helps to keep the human body humming, most notably by synthesizing proteins that carry out a range of cellular processes.

3 Aug 2026

Research Decodes How Gut Microbes Process Plant-Based Nutrients

Plant-based diets are good for you. They promote gut, immune, metabolic and cardiovascular health, in part by cultivating a diverse community of intestinal bacteria.

28 Jul 2026

Gut Bacteria Metabolites Successfully Boost Immune Response to Melanoma Tumors

A new study from a team including University of Nebraska–Lincoln researchers is the first to show metabolites produced by certain bacteria in the gut can positively impact the body's immune response to cancer.

15 Jul 2026

First-of-Its-Kind Surgery Performed on Western Lowland Gorilla at the San Diego Zoo Safari Park

Mizani, a 12-year-old male western lowland gorilla at the San Diego Zoo Safari Park, underwent a first-of-its-kind mastoidectomy to treat an infection that had spread into portions of his skull.

13 Jul 2026

New Science Study Reveals Genetic Secrets of High Altitude Mice Survival

Even for elite mountain climbers, reaching the summits of the Central Andes is an arduous undertaking. Atop these peaks - some of which reach elevations of almost 7,000 meters - it's a perennial winter, with temperatures rarely rising above freezing.

11 Jul 2026

Novel Study Reveals Hidden Biological Drivers Behind Cancer Induced Appetite Loss

Cachexia is a condition in which patients affected by cancer or other chronic diseases become sick and lose weight. The condition often involves brain-related symptoms of sickness, such as loss of appetite, which can lead to loss of muscle and often fat.

10 Jul 2026

Gut Bacteria Actively Manage Vitamin A Delivery for T Cell Maturation

Scientists at UT Southwestern Medical Center have discovered that gut bacteria help regulate the development of the body's immune system by directing the movement of vitamin A through a previously unrecognized cellular network.

8 Jul 2026