Fibrosis News and Research

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Fibrosis is the growth of fibrous tissue.

New RNA Extraction Approaches Overcome Agarose Barriers in Lung Slices

Precision-cut lung slices allow researchers to study living human lung tissue outside the body, preserving the different cell types and structures that make up the organ.

24 Oct 2026

Nagoya University Team Identifies BCAT1 Enzyme as Key Driver of Cardiac Fibrosis

Heart failure often develops after a heart attack because excessive collagen-based scar tissue forms during repair. While collagen is necessary to reinforce scars, disease and chronic inflammation can cause overproduction, which stiffens the heart muscle and impairs its pumping ability.

10 Oct 2026

Undigested Cellular Waste Secretes Toxic Signals That Zombify Surrounding Tissue

As we grow older, our bodies accumulate "zombie cells"-living cells that have stopped dividing or functioning normally-but linger in our tissues, contributing to chronic inflammation and age-related diseases.

6 Oct 2026

Spatial Single-Cell Transcriptomics Maps Cellular Niches in Fatal COVID-19 Lungs

Researchers at the University of Liège have used imaging-based spatial single-cell transcriptomics to map the cellular organization of lungs from people who died with severe COVID-19.

5 Oct 2026

Gut-Derived Neutral Ceramidase Regulates MASH Through Microbial and Epithelial Signaling

Metabolic dysfunction-associated steatohepatitis (MASH) is often viewed through the lens of hepatic lipid accumulation, inflammation and fibrosis.

30 Sep 2026

Single-Cell Sequencing Confirms Epigenetic Remodeling Across Diverse Cardiac Cell Types

The adult human heart is a reliable and resilient engine fueling our everyday lives while also being responsive enough to supercharge a Usain Bolt sprint or sustain a three-week bike race in the French Alps and Pyrenees.

29 Sep 2026

Engineered 3D miBrains Model Human Neurovascular Units and Pathology

Mount Sinai researchers have identified how APOE4, the strongest genetic risk factor for Alzheimer's disease, damages the brain's blood vessels and promotes the buildup of abnormal proteins linked to neurodegenerative disease.

26 Sep 2026

3D Stem-Cell miBrains Model Complex Neurovascular Pathology in Human Tissue

25 Sep 2026

Multi-Receptor Blocking Achieves Superior Antifibrotic Response Over Single-Receptor Inhibition

Three adenosine receptor subtypes that normally send different signals were found to converge on a common pathway that activates cardiac fibroblasts, the scar-forming cells in the heart. Blocking the receptors together produced a much stronger antifibrotic effect than blocking them one at a time.

25 Sep 2026

Marine Carbohydrate Therapeutics: From Structural Diversity to Clinical Translation

The ocean contains diverse carbohydrates that could serve as valuable resources for drug development. Algae, marine animals and microorganisms produce polysaccharides and related molecules with structures that are uncommon on land, including distinctive sulfate patterns, sugar linkages and branched architectures.

24 Sep 2026

Researchers Analyze Somatic DNA Integrity across Complex Longevity Pathways

A new review was published in Volume 18 of Aging on August 26, 2026, titled "Assessing mechanisms and evidence of a causal role for cellular senescence and somatic mutations in aging."

15 Sep 2026

Hidden Immune Cells May Hold Key to Tackling Female Infertility

University of Manchester scientists have uncovered a hidden role for immune cells in the womb, opening the door to new treatments for infertility, miscarriage and other reproductive conditions that affect millions of women worldwide.

10 Sep 2026

Protein Interaction Helps Senescent Cells Survive Aging and Cellular Stress

Senescent cells - cells that have stopped dividing but remain metabolically active - can accumulate with age and contribute to chronic inflammation and tissue dysfunction

2 Sep 2026

Bacterial Protein Fragment Disrupts Cell Quality Systems Causing Tissue Scarring

A bacterial protein fragment called corisin drives the process of pulmonary fibrosis by infiltrating and disrupting the cell's quality-control system, researchers at the University of Illinois Urbana-Champaign and Mie University in Japan found in a new study.

1 Sep 2026

Next-Generation RNA Therapeutic Approach Offers Hope for Treating Diverse Genetic Diseases

Researchers at the University of Toronto have developed a next-generation RNA therapeutic approach with the potential to treat a wide range of genetic diseases that share certain disease-causing mutations.

28 Aug 2026

Cells Deploy Specialized Quality Control Factors When Protein Synthesis Fails

Scientists at the Center for Molecular Medicine Cologne (CMMC) and the CECAD Cluster of Excellence on Aging Research have demonstrated in a biomedical study that ribosomes, the protein factories of our cells, face an unusually tough challenge when building large, membrane‑embedded proteins.

13 Aug 2026

McMaster Team Identifies Natural Immune Defense Against Advanced Fatty Liver Disease

Researchers at McMaster University have discovered that a naturally occurring hormone best known for suppressing appetite and promoting weight loss also helps protect the liver from inflammation through a previously unknown signaling pathway, opening new possibilities for treating advanced fatty liver disease.

11 Aug 2026

Fibrosis News and Research

New RNA Extraction Approaches Overcome Agarose Barriers in Lung Slices

Nagoya University Team Identifies BCAT1 Enzyme as Key Driver of Cardiac Fibrosis

Undigested Cellular Waste Secretes Toxic Signals That Zombify Surrounding Tissue

Spatial Single-Cell Transcriptomics Maps Cellular Niches in Fatal COVID-19 Lungs

Gut-Derived Neutral Ceramidase Regulates MASH Through Microbial and Epithelial Signaling

Single-Cell Sequencing Confirms Epigenetic Remodeling Across Diverse Cardiac Cell Types

Engineered 3D miBrains Model Human Neurovascular Units and Pathology

3D Stem-Cell miBrains Model Complex Neurovascular Pathology in Human Tissue

Multi-Receptor Blocking Achieves Superior Antifibrotic Response Over Single-Receptor Inhibition

Marine Carbohydrate Therapeutics: From Structural Diversity to Clinical Translation

Researchers Analyze Somatic DNA Integrity across Complex Longevity Pathways

Hidden Immune Cells May Hold Key to Tackling Female Infertility

Protein Interaction Helps Senescent Cells Survive Aging and Cellular Stress

Bacterial Protein Fragment Disrupts Cell Quality Systems Causing Tissue Scarring

Next-Generation RNA Therapeutic Approach Offers Hope for Treating Diverse Genetic Diseases

Cells Deploy Specialized Quality Control Factors When Protein Synthesis Fails

McMaster Team Identifies Natural Immune Defense Against Advanced Fatty Liver Disease

Localized Biochemical Halos Shield Pancreatic Beta Cells From Rejection

Protein Discovery Sheds Light on Scarring Diseases

Scientists Uncover Unexpected Mechanism Behind Extreme Antibiotic Resistance

The Future of Vision Restoration With ReVision Implant

How a Single List Is Changing Visibility for Women in Science

How Avatar Medical's 3D Technology Is Transforming How We Visualize the Human Body

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