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Cryo-Optical Microscopy Captures Instantaneous Snapshots of Cellular Waves

Cryo-Optical Microscopy Captures Instantaneous Snapshots of Cellular Waves

Optical microscopy is a key technique for understanding dynamic biological processes in cells, but observing these high-speed cellular dynamics accurately, at high spatial resolution, has long been a formidable task.

25 Aug 2025

Comprehensive Guide Sets New Standards for Plant Fluorescence Imaging

Comprehensive Guide Sets New Standards for Plant Fluorescence Imaging

A team of expert scientists led by Kirk Czymmek, PhD, director of the Advanced Bioimaging Laboratory at the Donald Danforth Plant Science Center and Heather E. McFarlane, assistant professor at the University of Toronto and collaborators from the Danforth Center, University of Leeds (UK), University of Massachusetts (Amherst), University of California - Davis, University of Naples Federico II, University of Minnesota and Université de Montréal, have authored a comprehensive guide to elevate the quality, transparency, and reproducibility of fluorescence microscopy in plant research. The guide was recently published in the journal Plant Cell, "Best Practices in Plant Fluorescence Imaging and Reporting: A Primer"

22 Aug 2025

New Imaging System Reveals Cellular Activity at Unprecedented Depths

New Imaging System Reveals Cellular Activity at Unprecedented Depths

Both for research and medical purposes, researchers have spent decades pushing the limits of microscopy to produce ever deeper and sharper images of brain activity, not only in the cortex but also in regions underneath such as the hippocampus.

8 Aug 2025

OLED Materials Have Potential New Uses in Detecting Pesticides for the Farming Industry

OLED Materials Have Potential New Uses in Detecting Pesticides for the Farming Industry

Researchers are set to shine a different kind of light on the farming industry after receiving funding to explore how fluorescent materials can detect the presence of pesticides and herbicides in food production.

8 Aug 2025

Parkinson’s Gene Mutation Blocks Vital Neuroprotective Signals

Parkinson’s Gene Mutation Blocks Vital Neuroprotective Signals

GBA1 mutations impair ciliary Hedgehog signaling in Parkinson's disease, reducing neuroprotective factors and highlighting a shared pathogenic pathway.

7 Aug 2025

CD276 Antibody Strategy Offers Hope For Immune-Resistant Lung Tumors

CD276 Antibody Strategy Offers Hope For Immune-Resistant Lung Tumors

The study highlights 8H8_SDIE's role in activating NK cells against NSCLC, offering a new strategy for patients resistant to conventional immunotherapies.

6 Aug 2025

Neuron-Like Telocytes Directly Connect to Stem Cells in the Intestine

Neuron-Like Telocytes Directly Connect to Stem Cells in the Intestine

In a key advance for regenerative medicine and gut health, scientists from Duke-NUS Medical School and Nanyang Technological University, Singapore (NTU Singapore) have uncovered a precise and unexpected communication system in the gut.

24 Jul 2025

Regulators of Cancer Cell Communication During Invasion

Regulators of Cancer Cell Communication During Invasion

This study identifies key genes regulating neural crest functions in melanoma, revealing insights into collective migration and potential therapeutic targets.

16 Jul 2025

SNAP-tag2 System Improves Protein Imaging with Faster, Brighter Labeling

SNAP-tag2 System Improves Protein Imaging with Faster, Brighter Labeling

SNAP-tag2 boosts live-cell imaging with faster labeling, brighter fluorescence, and better protein tracking across biological systems.

11 Jul 2025

Genetically Similar Bacteria Show Unexpected Diversity in Shape and Behavior

Genetically Similar Bacteria Show Unexpected Diversity in Shape and Behavior

Genetically similar bacteria can differ in shape and behavior, even in lab settings. A recent study shows that this variability impacts microbial fitness, virulence, and our understanding of gut microbiota.

26 Jun 2025

Fluorescent Molecules Offer Unprecedented Insight into Cell Structures

Fluorescent Molecules Offer Unprecedented Insight into Cell Structures

Scientists have long used fluorescent dyes—which emit light—to research cell structures and activities.

25 Jun 2025

Spatial Transcriptomics Reshapes Musculoskeletal Research and Therapy

Spatial Transcriptomics Reshapes Musculoskeletal Research and Therapy

Conventional transcriptomic techniques have revealed much about gene expression at the population and single-cell level—but they overlook one crucial factor: spatial context.

10 Jun 2025

Study Explores Use of Laser-Patterned Diamonds in Stem Cell Applications

Study Explores Use of Laser-Patterned Diamonds in Stem Cell Applications

A study in Advanced NanoBiomed Research presents laser-graphitized diamond electrodes that support human mesenchymal stem cell adhesion, alignment, and proliferation, advancing bioelectronic applications.

10 Jun 2025

Chitin Facilitates Gene Transfer Across Species Through Natural Transformation Among Vibrio cholerae

Chitin Facilitates Gene Transfer Across Species Through Natural Transformation Among Vibrio cholerae

A study in PNAS reveals that chitin promotes gene transfer in marine environments by binding environmental DNA and enhancing natural transformation in Vibrio cholerae, with implications for microbial evolution and ecosystem diversity.

6 Jun 2025

New LLNL Method Accelerates Protein Screening for Drug Discovery

New LLNL Method Accelerates Protein Screening for Drug Discovery

Machine learning and supercomputing have brought about a revolution in computational drug discovery.

24 May 2025

New Bacterial Consortium can Inhibit Bacterial Pathogens in Aquaculture

New Bacterial Consortium can Inhibit Bacterial Pathogens in Aquaculture

A new study by Danish researchers has demonstrated that it is possible to develop a consortium of bacteria that can inhibit bacterial pathogens in aquaculture.

22 May 2025

Visualizing Intracellular Molecular Landscapes in Single Cells

Visualizing Intracellular Molecular Landscapes in Single Cells

The t-SPESI method enables real-time visualization of intracellular lipids, offering insights into disease mechanisms and improving diagnostic tool development.

15 May 2025

Haematococcus pluvialis Microalga-Derived Nanoparticles Offer Eco-Friendly Boost for Plant Growth and Seed Priming

Haematococcus pluvialis Microalga-Derived Nanoparticles Offer Eco-Friendly Boost for Plant Growth and Seed Priming

Algae-derived nanoparticles from Haematococcus pluvialis enhance maize seed growth and microbial health, offering a green solution for sustainable agriculture.

13 May 2025

Role of LADs and Epigenetic Pathways in Nuclear Architecture During Early Mouse Embryo Development

Role of LADs and Epigenetic Pathways in Nuclear Architecture During Early Mouse Embryo Development

A new study in Cell reveals that lamina-associated domains (LADs) in early mouse embryos are shaped by dynamic epigenetic pathways, highlighting how histone modifications and chromatin structure guide nuclear architecture during development.

6 May 2025

3D Printing Collagen Scaffolds with Perfusable Systems for Tissue Engineering

3D Printing Collagen Scaffolds with Perfusable Systems for Tissue Engineering

Scientists have developed high-resolution 3D-printed collagen scaffolds with internal perfusion systems, enabling complex, vascularized tissue models that support cell viability, growth, and insulin secretion

6 May 2025

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