Gene Expression News and Research

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Gene Expression is the process by which a gene gets turned on in a cell to make RNA and proteins. Gene expression may be measured by looking at the RNA, or the protein made from the RNA, or what the protein does in a cell.

Turning Human Fat into Insulin-Producing Organoids That Reverse Diabetes

By preserving fat tissue architecture, researchers created organoids that restore insulin function, paving the way for advancements in diabetes treatment.

8 Jan 2026

Dual Genetic Mutations Drive RNA Mis-Splicing and Leukemia Progression

Treating acute myeloid leukemia (AML) depends on knowing what goes wrong inside cells. A new study suggests that two genetic mutations – IDH2 and SRSF2 – work cooperatively to mis-splice RNA messages and change how blood cells develop.

6 Jan 2026

Blocking Retinoic Acid Pathway Improves Dendritic Cell Anti-Tumor Function

Scientists at the Princeton University Branch of the Ludwig Institute for Cancer Research have identified novel mechanisms by which a metabolic derivative of vitamin A-all-trans retinoic acid-compromises both the body's normal anti-cancer immune response and, in a different context, the efficacy of a promising type of cancer vaccine.

6 Jan 2026

LINE-1 Retrotransposons Reshape Cancer Genome Architecture

Scientists at St. Jude Children's Research Hospital have revealed previously unappreciated roles for the retrotransposon LINE-1 in shaping the cancer genome structure and regulation.

6 Jan 2026

Aging Alters a Common Set of RNA Splicing and Processing Genes Across Tissues

A new research paper featured as the cover of Volume 17, Issue 12 of Aging-US was published on December 22, 2025, titled "A combination of differential expression and network connectivity analyses identifies a common set of RNA splicing and processing genes altered with age across human tissues."

6 Jan 2026

Gut Microbiome Plays a Direct Role in Shaping Brain Function and Evolution

A groundbreaking new study reveals that changes to the gut microbiome can change the way the brain works.

6 Jan 2026

Interferon Response in Female Brains Linked to Alzheimer's Progression

More than seven million Americans have Alzheimer's disease, and two-thirds of them are women, according to the Alzheimer's Association. The O'Banion Lab at the Del Monte Institute for Neuroscience at the University of Rochester has long been studying this disease and is looking more closely at the differences between male and female brains.

30 Dec 2025

New ddHodge Method Reconstructs Cell Fate Dynamics with High Accuracy

Researchers from Kyushu University have developed an innovative computational method, called ddHodge, that can reconstruct the complex dynamics of how cells decide their fate. As reported in Nature Communications, this approach paves the way for a deeper understanding of the biological processes involved in development, regeneration, and disease.

30 Dec 2025

Computational Tool Maps the Dance of Circadian Synchrony

What makes someone a "morning lark" or a "night owl?" Why does jet lag hit us so hard, and why do some people struggle each winter with seasonal affective disorder?

26 Dec 2025

Stem Cells Mimic Earliest Stages of Brain Development in a Dish

Researchers have made great strides to understand early signs of autism. Studies have found that certain factors like genetics, sleep deprivation, excess fluid in the brain-and brain size-can increase the risk of neurodevelopmental conditions, like autism.

26 Dec 2025

Stem Cell Models Offer Insights Into Early Brain Development and Autism

24 Dec 2025

Mapping the Four Dimensional Organization of the Human Genome

A new study challenges what's long been assumed about genetic variants thought to always cause inherited blindness.

23 Dec 2025

Calcium Signaling Suppresses Lignin Accumulation in Pear Stone Cells

Stone cells arise from lignified secondary cell walls and cause a gritty texture, reduced sweetness, and poor flavor in many pear cultivars.

23 Dec 2025

Researchers Map Gene Activation in Lethal Fungal Outbreaks

Scientists have discovered a genetic process which could unlock new ways to treat mysterious and deadly fungal infection which has shut down multiple hospital intensive care units.

22 Dec 2025

Researchers Uncover Gene Control Elements Tied to Alzheimer’s Disease

When most of us think of DNA, we have a vague idea it's made up of genes that give us our physical features, our behavioral quirks, and keep our cells and organs running.

19 Dec 2025

A Molecular Tug-of-War Shapes Gene Regulation and Disease

A newly revealed molecular tug-of-war may have implications for better understanding how a multitude of diseases and disorders - including cancers, neurodegenerative diseases and immune disorders - originate, as well as how to potentially treat them, according to researchers at Penn State.

18 Dec 2025