Gene Expression News and Research

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Gene Expression is the process by which a gene gets turned on in a cell to make RNA and proteins. Gene expression may be measured by looking at the RNA, or the protein made from the RNA, or what the protein does in a cell.

Scientists Uncover Inner Workings of Biomolecular Condensates Linked to ALS

Inside the cell reside many tiny assembly factories and warehouses that gather together all of the proteins and RNAs-which carry out instructions from our DNA-that a living being needs.

27 Nov 2025

Scientists Map How Transcription Factors Interpret DNA Sequences

With a new study in the journal Cell, researchers at Stanford University and Stockholm University have contributed to increased knowledge about gene regulation in human cells.

27 Nov 2025

DNA Rigidity Inside the Nucleosome Regulates INO80 Positioning

Researchers at The University of Texas MD Anderson Cancer Center have shown that DNA inflexibility, or rigidity, inside the nucleosome regulates the positioning of INO80. This highlights that the physical structure and shape of DNA, not just genetic information, are key components of DNA transcription.

26 Nov 2025

Discovery Reveals Unexpected Role for OTULIN in Controlling Tau Expression

Scientists have uncovered a surprising mechanism by which a brain enzyme called OTULIN controls the expression of tau, the protein that forms toxic tangles in Alzheimer's disease.

26 Nov 2025

Novel Mechanism for Epigenetic Patterning in Plants

Every cell within an organism shares an identical genetic blueprint. Their distinct identities stem from epigenetics—precise chemical markers that dictate gene expression.

24 Nov 2025

Cyanobacteria Change Their Genetic Activity After Sunset

Cyanobacteria, also referred to as blue-green algae, are found globally in diverse forms, encompassing both single-celled organisms and filamentous chains.

21 Nov 2025

Genetic Insights Reveal Key Drivers of Bone Density in Children

Researchers at Children's Hospital of Philadelphia (CHOP) revealed important genetic components that affect bone density in children and adolescents.

20 Nov 2025

Sabotaging T Cell Exhaustion for Cancer Therapy

Like all hardworking things, the cytotoxic T lymphocytes (CTLs) of the immune system charged with detecting and destroying cancer cells tend to get very tired-so much so, in fact, that they can even die from exhaustion.

18 Nov 2025

Researchers Discover Molecular Switch That Helps Breast Cancer Cells Survive Stress

Cells are regularly faced with environmental stresses that may damage or destroy them. To survive, they quickly adjust their gene expression to protect themselves.

18 Nov 2025

New "Ultra-Mild" Method Corrects Cancer DNA Methylation Test Errors

Traditional bisulfite sequencing damages DNA, while enzyme-based alternatives are inconsistent. A novel methylation analysis method, called UMBS-seq, was published this week in Nature Communications. UMBS-seq achieves both accuracy and gentleness, unlocking more reliable cancer biomarker detection.

13 Nov 2025

CellWhisperer Enables Natural Language Exploration of Single-Cell Biology

Using sophisticated RNA sequencing technology, biomedical researchers can measure the activity of our genes across millions of single cells, creating detailed maps of tissues, organs, and diseases.

12 Nov 2025

New Persimmon Genome Assembly Sheds Light on Early Flowering Ability

The genus Diospyros includes over 500 species, among which cultivated persimmon (D. kaki) holds great nutritional and economic importance.

10 Nov 2025

St. Jude Scientists Discover Hidden Binding Pocket in Nuclear Receptors

A study from St. Jude Children's Research Hospital uncovered an alternative binding pocket within nuclear receptors, revealing a much-needed new therapy route for this important class of drug targets.

7 Nov 2025

RNA Molecules Alter Genome Structure to Silence Critical Neuronal Genes During Stress

What if the brain's response to stress could be read not in fleeting neurotransmitter bursts, but in the quieting of genes deep inside chromatin? Researchers at the University of Alabama at Birmingham have now shown that stress hormones may silence crucial neuronal genes through an unexpected class of RNA molecules that operate not by encoding proteins, but by reshaping the genome's architecture.

5 Nov 2025

Weill Cornell Scientists Develop Safe and Precise Tool to Control Gene Activity

Investigators at Weill Cornell Medicine have developed a versatile and non-toxic technology for controlling the activity of any gene in a cell. Such "gene-switch" tools allow scientists to "turn on" or "turn off" a target gene to study how it works, model diseases and design new therapies.

4 Nov 2025