Gene Expression News and Research

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Gene Expression is the process by which a gene gets turned on in a cell to make RNA and proteins. Gene expression may be measured by looking at the RNA, or the protein made from the RNA, or what the protein does in a cell.

Molecular Map Matches Patient Tumors to Targeted Clinical Trial Therapies

A new molecular map of breast cancer has identified novel forms of the disease and provides a foundation for selecting personalized treatments guided by a tumor's molecular characteristics rather than standard pathology alone.

6 Nov 2026

Microgravity Drives the Metabolic Switch From Glycolysis to Oxidative Phosphorylation

Earth-based hiPSC models have transformed disease research but remain limited by cellular immaturity, a strong reliance on glycolysis rather than oxidative phosphorylation (OXPHOS), and incomplete tissue architecture.

4 Nov 2026

CRISPR Screen Uncovers COMPASS Pathway Role in Suppressing Gut Autoimmunity

3 Nov 2026

Langerhans Cell Projections Transmit Surface Microbial Signals to Stem Cells

As the steadfast protector of the body's interior, the skin must be able to swiftly respond to stressors from the outside world and then return to a steady state in order to maintain everyday operations.

2 Nov 2026

St. Jude Scientists Discover Gene-Regulatory Pathway Protecting Gut Immune Balance

Trillions of bacteria live in the human gut without triggering an immune response. Scientists at St. Jude Children's Research Hospital have now discovered a gene-regulatory pathway that helps maintain this delicate balance. Published today in Science Advances, they showed that a type of immune cell, regulatory T cells, co-opt a well-known general gene expression pathway called COMPASS to suppress inappropriate immune responses and prevent lethal inflammation and autoimmunity.

30 Oct 2026

Staged CsREF1-2 Application Boosts Transgenic Shoot Recovery in Citrus Species

Traditional breeding in citrus faces steep obstacles: apomixis produces maternal clones, a juvenile phase lasting 5 to 10 years delays fruiting, and high heterozygosity complicates trait inheritance.

29 Oct 2026

A New Way to Watch Plants Respond to Disease in Real Time

Scientists at the MRC Laboratory of Medical Sciences (LMS) have devised a novel method for improving the accuracy of luminescent biological reporters, which enables researchers to monitor gene expression in living plants for extended periods, including days, weeks, and potentially months or even years.

26 Oct 2026

New RNA Extraction Approaches Overcome Agarose Barriers in Lung Slices

Precision-cut lung slices allow researchers to study living human lung tissue outside the body, preserving the different cell types and structures that make up the organ.

24 Oct 2026

Genetic Clue to Autism's Fourfold Difference In Boys and Girls

Findings on MECP2 regulatory variants suggest genetic factors contribute to autism's male bias, enhancing understanding of the disorder's heritability.

22 Oct 2026

Functional Genomics Platform Connects Candidate Genes to Pest Defense Phenotypes

Cowpea (Vigna unguiculata) supplies dietary protein, livestock feed, and income in tropical and subtropical regions, while its nitrogen-fixing ability adds agricultural value. Genome sequencing has provided researchers with numerous candidate genes, and genetic transformation has enabled studies of traits such as drought and heat tolerance.

20 Oct 2026

Cold Responsive Transcription Factor Binding Overlaps Open Chromatin at Gene Promoters

Rice originated in subtropical environments, yet its cultivation has expanded into regions where low temperatures threaten growth, development, and yield. Japonica rice generally tolerates cold better than indica rice, and researchers have linked this adaptation to changes in stress-responsive gene expression. Much attention has focused on C-repeat binding factors, a group of transcription factors that help coordinate plant cold responses.

20 Oct 2026

Plant Circadian Clock Drives Molecular Salt Stress Defenses

Salty soil is a growing threat to crops worldwide. Hotter, drier weather has increased evaporation rates, drawing moisture from the soil and leaving behind concentrated mineral salts.

16 Oct 2026

Three-Dimensional Genome Architecture Actively Dictates Phenotypic Novelties in Octopuses

Octopuses, squid and cuttlefish, collectively known as coleoid cephalopods, have evolved exceptionally large and elaborately structured nervous systems capable of complex behaviors such as problem-solving and rapid camouflage.

10 Oct 2026

Single-Cell RNA Sequencing Maps Neuroblastoma Intratumoral Heterogeneity

Neuroblastoma is the most common solid tumor found outside of the brain in children, yet why some children respond well to treatment while others do not has remained poorly understood. St. Jude Children's Research Hospital scientists and their collaborators built one of the most comprehensive datasets of neuroblastoma cells to date, using it to define the tumor's cell types and identify a gene signature marking a malignant cell population tied to poor prognosis.

10 Oct 2026

Ten Shared Gene Clusters Map Common Immune Response Pathways Across Diseases

Researchers have identified patterns of gene activity associated with severe COVID-19 in children that are shared with other serious respiratory infections.

9 Oct 2026

Single-Molecule Optical Tweezers Visualize Real-Time Dynamic Protein and DNA Interactions

A protein that's essential to every cell's ability to turn off unnecessary genes is well known for its key function of compacting genes and its connection to cancer when it undergoes mutation.

1 Oct 2026

Single-Molecule Optical Tweezers Visualize Real-Time Dynamic Protein and DNA Interactions

A protein that's essential to every cell's ability to turn off unnecessary genes is well known for its key function of compacting genes and its connection to cancer when it undergoes mutation. But until now, scientists weren't quite sure how the protein gets where it needs to go to keep genes bound up so they aren't activated.

1 Oct 2026

Single-Cell Metabolic Profiling Identifies Key Bioenergetic Targets in Human Tumor Tissue

Immune cells can reach head and neck tumors, but once there, many stop functioning. This helps explain why immunotherapy with immune checkpoint inhibitors - which have transformed treatment for some cancers - benefit only 17%–23% of patients with head and neck squamous cell carcinoma. These are cancers that arise from cells lining the mouth, throat and voicebox.

1 Oct 2026

Targeted Y Chromosome Deletions Disrupt Key Cellular Immune Response Pathways

A new study found that cancer cells selectively chip away gene-rich sections of the Y chromosome, triggering ripples that regulate tumor growth.

29 Sep 2026

Study Links OCA2 Gene Mutations to Non-Melanin Ocular Developmental Defects

Tiny, striped zebrafish are helping scientists trace how a gene linked to albinism influences eye development, work that may ultimately help explain some of the vision problems experienced by people with the condition and guide the search for new treatments.

29 Sep 2026

Gene Expression News and Research

Further Reading

Molecular Map Matches Patient Tumors to Targeted Clinical Trial Therapies

Microgravity Drives the Metabolic Switch From Glycolysis to Oxidative Phosphorylation

CRISPR Screen Uncovers COMPASS Pathway Role in Suppressing Gut Autoimmunity

Langerhans Cell Projections Transmit Surface Microbial Signals to Stem Cells

St. Jude Scientists Discover Gene-Regulatory Pathway Protecting Gut Immune Balance

Staged CsREF1-2 Application Boosts Transgenic Shoot Recovery in Citrus Species

A New Way to Watch Plants Respond to Disease in Real Time

New RNA Extraction Approaches Overcome Agarose Barriers in Lung Slices

Genetic Clue to Autism's Fourfold Difference In Boys and Girls

Functional Genomics Platform Connects Candidate Genes to Pest Defense Phenotypes

Cold Responsive Transcription Factor Binding Overlaps Open Chromatin at Gene Promoters

Plant Circadian Clock Drives Molecular Salt Stress Defenses

Three-Dimensional Genome Architecture Actively Dictates Phenotypic Novelties in Octopuses

Single-Cell RNA Sequencing Maps Neuroblastoma Intratumoral Heterogeneity

Ten Shared Gene Clusters Map Common Immune Response Pathways Across Diseases

Single-Molecule Optical Tweezers Visualize Real-Time Dynamic Protein and DNA Interactions

Single-Molecule Optical Tweezers Visualize Real-Time Dynamic Protein and DNA Interactions

Single-Cell Metabolic Profiling Identifies Key Bioenergetic Targets in Human Tumor Tissue

Targeted Y Chromosome Deletions Disrupt Key Cellular Immune Response Pathways

Study Links OCA2 Gene Mutations to Non-Melanin Ocular Developmental Defects

The Future of Vision Restoration With ReVision Implant

How a Single List Is Changing Visibility for Women in Science

How Avatar Medical's 3D Technology Is Transforming How We Visualize the Human Body

Editorial Focus eBook - Biopharmaceuticals (2nd edition)

Improving Cell Culture Efficiency with Image-Guided Automation

Improving Scalability in Organoid Research

Cosmetic Formulation and Manufacturing

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