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New "DNA Organizer" Found to Be Essential for Sperm Stem Cell Development

A research team at Kyoto University has discovered STAG3-cohesin, a new mitotic cohesin complex that helps establish the unique DNA architecture of spermaotogonial stem cells (SSCs), the stem cells that give rise to sperm.

27 Aug 2025

Plant Genetics Research Reveals Dynamic and Diverse Centromere Behavior

Cell division is an essential process by which living organisms grow, replenish lost cells, and regenerate dead and damaged tissues.

8 Aug 2025

Uncovering How Cells Precisely Control Protein Production

It's known as biology's central dogma: All living organisms' genetic information is stored in DNA, which is transcribed into RNA, which is translated into proteins that perform nearly all essential tasks in a cell.

6 Aug 2025

Rewriting rRNA Alters the Architecture of the Nucleolus

Ribosomes carry out the cell's most essential function-translating genetic information into proteins.

28 Jul 2025

New Research Reveals Key Protein Behind Plant Heat Tolerance

While humans can escape the heat by seeking shade or shedding layers, plants remain rooted in place. So how do they survive extreme heat? It's a question many have wondered-and now, science has an answer.

15 Jul 2025

Iowa State Engineers Reinvent Gene Gun for Faster and Safer Crop Editing

Plant scientists have used a standard "gene gun" since 1988 to genetically modify crops for better yield, nutrition, pest resistance and other valuable traits.

5 Jul 2025

UChicago Team Receives Grant to Study RNA Splicing and Cell Stress

During the first step of converting genetic information into functional proteins, cells transcribe the double-stranded helix of DNA into single strands of RNA.

3 Jul 2025

Scientists Reveal Molecular Battle Between Maternal and Paternal Genes in Bees

Despite having identical genetic instructions, female honey bee larvae can develop into either long-lived reproductive queens or short-lived sterile workers who help rear their sisters rather than laying their own eggs.

23 Jun 2025

Hundreds of Human Genes Found to Act Like On Off Switches

Gene expression, where cells use the genetic information encoded in DNA to produce proteins, has been thought of as a dimmer light.

19 Jun 2025

TUM Scientists Develop Breakthrough Method to Monitor CAR-T Cells

In modern immunotherapy, modified immune cells are introduced into the body to attack tumors and other targets.

16 Jun 2025

Study Reveals RNA Polymerase I Stalling Mechanism at Abasic DNA Damage Sites

New study shows RNA polymerase I halts at abasic DNA damage, helping prevent faulty rRNA production and exposing lesions for repair in dividing cells.

16 Jun 2025

Large Language Models Unlock New Frontiers in Plant Genomics

By leveraging the structural parallels between genomic sequences and natural language, these AI-driven models can decode complex genetic information, offering unprecedented insights into plant biology.

2 Jun 2025

Geisinger Scientists Uncover Genetic Basis for Sex-Based Height Variation

Geisinger's study reveals Y chromosome genes significantly influence height differences between sexes, highlighting genetic factors beyond hormones.

21 May 2025

How LEM-3 Cleaves DNA Bridges During Cell Division Revealed

If DNA bridges remain between chromosomes after cell division, chromosomes become improperly segregated, resulting in genetic instability and cancer.

20 May 2025

Molecular Mechanism Revealed by Stop-Motion Electron Microscopy

Using electron microscopy, researchers illustrate FusB's role in antibiotic resistance, providing a molecular-level understanding of fusidic acid interactions.

19 May 2025

Cryo-EM Reveals Protein-Free RNA Structures in Bacterial Cells

Cryogenic electron microscopy showed for the first time that large RNA complexes can assemble without the help of proteins, expanding our understanding of RNA folding and function.

10 May 2025

Scientists Use AI to Predict Future Viruses and Design Better Vaccines

Effective vaccines dramatically changed the course of the COVID-19 pandemic, preventing illness, reducing disease severity, and saving millions of lives.

10 May 2025

Super Stem Cells Offer New Hope for IVF and Regenerative Medicine

The ‘super stem cells’ perform better than regular stem cells, being able to develop into many different cell types, researchers from the University of Copenhagen find, with many potential applications, including improved IVF treatment.

25 Apr 2025

Complete Reference Genomes Unlocked for Six Ape Species

Comprehensive reference genomes have now been assembled for six ape species: siamang (a Southeast Asian gibbon), Sumatran orangutan, Bornean orangutan, gorilla, bonobo and chimpanzee.

12 Apr 2025

Scientists Capture Dynamic Process of Chromatin Remodeling in Action

Chromatin remodeling plays a vital role in gene regulation, affecting how DNA is accessed. Disruptions in this process can also lead to cancer and other diseases.

7 Apr 2025