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New Insights Into LARP6-RNA Binding Could Lead to Fibrosis Therapies

A research team at the Institute of Molecular Biophysics and the Department of Chemistry and Biochemistry at Florida State University has made a significant discovery regarding the interaction between a protein present in the human body and RNA, which may pave the way for innovative treatments for tissue scarring, commonly referred to as fibrosis.

12 Dec 2025

Researchers Elucidate Microtubule-Mediated Cell Signal Transduction

The most diverse functions of a cell in the human body – from cell division and differentiation to motility and programmed cell death – are controlled by signaling proteins within the cell. This includes the immune system and the reading of genetic information.

11 Dec 2025

Computational Method can Detect How Genes Interact to Influence Complex Human Traits

A new study has developed a powerful computational method that can detect how genes interact with each other to influence complex traits in humans at a scale previously impossible.

11 Dec 2025

Real-Time Visualization Reveals the Transcriptional Gearbox

Life's instructions are written in DNA, but it is the enzyme RNA polymerase II (Pol II) that reads the script, transcribing RNA in eukaryotic cells and eventually giving rise to proteins.

28 Nov 2025

DNA Rigidity Inside the Nucleosome Regulates INO80 Positioning

Researchers at The University of Texas MD Anderson Cancer Center have shown that DNA inflexibility, or rigidity, inside the nucleosome regulates the positioning of INO80. This highlights that the physical structure and shape of DNA, not just genetic information, are key components of DNA transcription.

26 Nov 2025

Novel Mechanism for Epigenetic Patterning in Plants

Every cell within an organism shares an identical genetic blueprint. Their distinct identities stem from epigenetics—precise chemical markers that dictate gene expression.

24 Nov 2025

Chaperone-Shielding Mechanism Regulates Protein Glycosylation

Proteins are often called the building blocks of cells, but even those building blocks need to be built. One of the most important steps in the process of building proteins is glycosylation, when sugar molecules (glycans) are attached to the maturing protein.

20 Nov 2025

Reviving Ancient DNA Techniques to Study Historical Disease Evolution

Research institutions around the world house valuable genetic information that could help unlock countless medical mysteries.

17 Nov 2025

Studying Disease Evolution Through Ancient DNA Analysis

Research institutions around the world house valuable genetic information that could help unlock countless medical mysteries. However, because DNA degrades over time, it is difficult for researchers to analyze DNA samples older than 20 years using conventional analytical approaches.

14 Nov 2025

Study Exposes Critical Security Flaws in Widely Used DNA Sequencing Tech

Portable genetic sequencers used around the world to sequence DNA have critical, previously unreported security vulnerabilities that could reveal or alter genetic information without detection, according to a new study.

11 Nov 2025

Human Pangenome Research Opens a New Chapter in Precision Medicine

In May 2023, the Human Pangenome Reference Consortium (HPRC) released the first draft of the human pangenome reference sequence, which integrated genomic data from 47 individuals representing genetic diversity and added 119 million base pairs of euchromatic polymorphic sequences.

10 Nov 2025

Researchers Find "Hidden" Mutations by Tracing Protein Isoforms

Approximately 25 million individuals in the United States are affected by a rare genetic disorder, and a significant number of them face challenges not only due to the absence of effective treatments but also because of insufficient information regarding their condition.

10 Nov 2025

Protein Dysfunction Could be the Cause of Diseases Resulting From Shortened Telomeres

New research from the University of Wisconsin–Madison reveals that dysfunction in a protein essential to maintaining stability in our chromosomes may be responsible for serious - and sometimes deadly - diseases.

31 Oct 2025

How Gut Bacteria Influence Mammalian Cell Physiology

The microbiome-the trillions of bacteria, viruses, and fungi that live quietly in our body-plays a crucial role in shaping human health by providing a variety of micronutrients necessary for vital functions.

30 Oct 2025

AI-Powered Approach Boosts Protein Production Efficiency in E. coli

Proteins sourced from microorganisms are attracting attention for their potential in biomanufacturing a variety of products, including pharmaceuticals, industrial enzymes, and diagnostic antibodies.

29 Oct 2025

Combating Influenza A Virus with CRISPR and Human Lung Organ Chips

The Influenza A virus (IAV) has been the cause of six major flu pandemics, responsible for 50 to 100 million deaths globally.

16 Oct 2025

New Genetic Insights Offer Hope for Early Detection of Osteosarcoma

Researchers at Cleveland Clinic Children's have helped identify a previously unknown gene that increases the risk of developing osteosarcoma, the most common type of malignant bone tumor in children and young adults.

10 Oct 2025

New Research Challenges the Static View of Chromosome Shape

An international team of researchers from the Francis Crick Institute, Imperial College London, Waseda University, and the Cancer Institute of the Japanese Foundation for Cancer Research has reshaped the concept of chromosome shape, discovering that they are not always stable X-shaped structures but are constantly in flux as cell division occurs.

24 Sep 2025

Advanced Statistical Method Reduces Noise in Single-Cell RNA-Sequencing Data

The world of cells is surprisingly noisy. Each cell carries unique genetic information, but when we try to measure cellular activity, signals can be lost or blurred, and differences between experiments can further obscure the data.

18 Sep 2025

New "DNA Organizer" Found to Be Essential for Sperm Stem Cell Development

A research team at Kyoto University has discovered STAG3-cohesin, a new mitotic cohesin complex that helps establish the unique DNA architecture of spermaotogonial stem cells (SSCs), the stem cells that give rise to sperm.

27 Aug 2025