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Open-Source Genomic Tool Accelerates Diagnoses for Rare Diseases

A newly developed open-source tool designed for rigorous reanalysis of genomic data is highly effective at detecting new rare disease diagnoses.

26 Jun 2026

Scientists Decode 3D Structure of Vision Proteins to Fight Blindness

They allow us to see the world in thousands of colors: red strawberries, green leaves, the blue sky.

26 Jun 2026

Scientists Discover Hidden Protein Variant Driving Severe COVID-19 and Lung Fibrosis

A genetic difference carried by nearly one in three people may increase the risk of severe COVID-19 and lung fibrosis by disrupting the function of a previously unknown protein, according to a new study.

25 Jun 2026

Researchers Discover Molecules Targeting Vital Cell Signaling Proteins

To function normally, nearly every cell in the human body relies on G-protein coupled receptors (GPCRs) to receive and send signals. That's why GPCRs are targeted by roughly one-third of all FDA‑approved drugs.

25 Jun 2026

Decoding Hidden Metabolic Tissue Crosstalk via Advanced Proteomic Tracking

The body's organs are in constant communication. Fat tissue tells the liver when to store or release energy, the immune system signals localized inflammation, and thousands of proteins carry these messages to organs throughout the body.

23 Jun 2026

Taste and Smell Genetic Receptors Shape Long-Term Disease Risks

Imagine if a doctor could look at your DNA and predict not just your disease risk, but also which foods you're drawn to – and whether those cravings are quietly protecting you.

19 Jun 2026

Study Identifies Protein Involved as Key Structural Anchor for Bacterial Membranes

Researchers at the University of Notre Dame and collaborators have discovered a key process for how the outer membrane of gram-negative bacteria attaches to the cell wall, advancing the understanding of how these bacteria frequently manifest resistance to antibiotics.

16 Jun 2026

Streamlining Complex Drug Development by Directly Editing Core Molecular Frameworks

For more than a hundred years, chemists have been building complex molecules step by step – bond by bond, atom by atom.

16 Jun 2026

Study Identifies Novel Interaction Between an Innate Immune Receptor and an Enzyme

Traumatic brain injuries (TBI) - even mild concussions - may trigger a chain reaction in the brain that disrupts neuronal communication.

13 Jun 2026

Scientists Track Tiny Human Proteins Using Novel Laser Phase Plate

In a landmark achievement in biological imaging, researchers at the University of California, Berkeley and Biohub today announced the successful demonstration of the laser phase plate.

12 Jun 2026

Researchers Identify a Dedicated Gut-Brain Signaling Pathway That Helps Drive Hunger

Researchers at the Monell Chemical Senses Center found that common dietary sugars fructose and glucose, despite having the same amount of calories, communicate with the brain through different gut-brain pathways, a difference that may help shape our food and beverage preferences.

12 Jun 2026

Ancient Genome Duplications Fueled the Evolution of Complex Brains

New findings, published today (10 June) in Nature, help to answer the riddle of how vertebrates evolved the diverse array of brain cells that distinguishes them from other animals.

11 Jun 2026

Building More Realistic Human Tissue Models With Assembloids

Assembloids combine organoids and specialized cells, creating advanced models for drug testing and regenerative medicine with improved physiological relevance.

11 Jun 2026

Study Reveals Mitochondria Plug Straight Into the Nuclear Command

For generations, textbooks have taught that a cell's energy simply drifts to wherever it is needed.

11 Jun 2026

Building A Soft Robotic Heart That Mimics HFpEF Progression

Researchers developed a soft robotic heart model that replicates HFpEF, enhancing understanding of the disease and supporting innovative treatment strategies.

10 Jun 2026

Microtubule Skeleton Determines How Heart Muscle Cells Change Under Stress

Microtubules, part of heart muscle cells' internal "skeleton," help determine how the heart changes shape under stress, and a common signaling pathway called the ERK pathway acts as a key controller of where the building materials for these cells' growth are delivered inside them, a pair of new studies show.

9 Jun 2026

Bispecific Antibodies Target Tumors While Sparing Healthy Tissue

A new generation of bispecific antibodies effectively targets cancer cells, minimizing toxicity and enhancing treatment precision in preclinical studies.

3 Jun 2026

A New Non-Destructive Tool Maps Active Transcription Profiles in Living Tissue

Cell function is determined by how DNA is expressed into proteins. That process includes two main steps - transcription, when messenger RNA (mRNA) makes copies of active genes, and translation, when mRNA guides protein assembly.

2 Jun 2026

Live-Imaging Techniques Reveal How Stem Cells Collectively Suppress Tumors

It all starts with a single cell.

2 Jun 2026

Researchers Find Simple Genetic Links for Extreme Traits

Researchers at the Icahn School of Medicine at Mount Sinai have found evidence that people who fall at the extreme high or low ends of certain traits, such as cholesterol, blood glucose, height, and age at menopause, are more likely to have a simple genetic explanation than previously thought.

28 May 2026