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New Gene-Editing Approach Eliminates Painful Crises in Sickle Cell Disease

New results from a clinical trial show promising outcomes for a gene-edited treatment for severe sickle cell disease, a genetic blood disorder with few curative options.

2 Apr 2026

Implantable Cell Factory Device Delivers Sustained Biologic Drug Production

Implanting living cells as long-term drug producers could transform treatment for numerous diseases, but it is difficult to house the tiny workers in quantities high enough to ensure dosage needs are met while also keeping the cells alive and thriving.

28 Mar 2026

New Platform Models Cancer Metastasis and Cell Cluster Survival

Metastasis, the spread of cancer from a primary tumor to other parts of the body, is difficult to study in the lab, in part because researchers lack reliable ways to recreate the conditions cancer cells encounter as they travel through the bloodstream.

28 Mar 2026

Genetic Analysis Reveals Why Haploid Fish Embryos Fail to Survive

Naturally occurring haploids are predominantly documented in plants; the first report dates to 1923, when haploid individuals were identified in the Jimson Weed.

27 Mar 2026

SLIT3 Protein Drives Brown Fat Activation Through Dual Signaling

Researchers have determined how a key protein activates brown fat by expanding blood vessels and nerves in the heat-generating tissue.

26 Mar 2026

New Mechanism Links Mitochondria Dysfunction to T Cell Exhaustion

The immune system's killer T cells do a commendable job of detecting and destroying cancer cells. But the harsh environment at the heart of tumors often saps them of their vitality, pushing them into a state of permanent lassitude called "terminal exhaustion."

23 Mar 2026

Sheep Genome Study Identifies Key Regulatory DNA Elements

Livestock breeders could soon have more tools to improve the health and quality of their animals, thanks to a recent study that sheds new light on regulatory elements in the sheep genome.

17 Mar 2026

4D Atlas Reveals Gene Activity During Embryo Development

How does a tiny cluster of cells become an embryo with a head, trunk, and tail? And how do thousands of genes coordinate this development? A new imaging method makes it possible to visualize the activity of thousands of genes simultaneously throughout the entire zebrafish embryo.

13 Mar 2026

Optovolution Uses Light to Guide the Evolution of Dynamic Proteins

Evolution is biology's powerful method of engineering. It works by generating many variants of DNA, RNA, and proteins inside cells and letting nature "select" the organism that performs best.

9 Mar 2026

Transplanted Mitochondria Enhance Cell Metabolism and Survival Under Stress

Mitochondria, also known as the powerhouses of the cell, are essential for cell survival, repair, and adaptation.

5 Mar 2026

Study Connects Gut Bacteria Patterns With Dyslipidemia Risk

Before the onset of cardiovascular disease symptoms, people often develop dyslipidemia, or abnormal levels of lipids in the blood.

5 Mar 2026

Scientists Develop Novel Tool to Profile Elusive HIV Reservoir Cells

For people living with human immunodeficiency virus (HIV), life-saving antiretroviral therapy keeps their HIV-infected immune cells from making new copies of the virus, preventing illness and transmission.

4 Mar 2026

Single-Cell Atlas Reveals Coordinated Aging Across Multiple Organs

As we age with each passing year, we become more susceptible to chronic diseases like cancer, heart disease, and dementia.

27 Feb 2026

Large-Scale Study Maps DNA Variants Shaping Human Disease Risk

Scientists have identified how specific genetic changes function in cells to influence disease risk and other human health traits.

26 Feb 2026

Structural Blueprint of Cellular Biomolecular Condensates Opens New Therapeutic Possibilities

Cells rely on biomolecular condensates to coordinate essential biological processes without surrounding membranes.

26 Feb 2026

Lab-Grown Brain Tissue Masters a Classic Computing Benchmark

Imagine balancing a ruler upright in the palm of the hand: There is a need to continually pay attention to the angle of the ruler and make several little changes to ensure it does not topple over.

20 Feb 2026

Plant Scientists Tackle Major Threat to UK Wheat

A fungus known as yellow rust can destroy wheat, reducing harvests and driving up prices, which in turn can affect the price of staple foods like bread and pasta.

13 Feb 2026

New Genetic Regulatory System Improves Cell Viability During Production of Gas Vesicles

Gas vesicles are among the largest known protein nanostructures produced and assembled inside microbial cells.

3 Feb 2026

Fruit Fly Neurons Explain When Food Feels Rewarding

Why do we sometimes keep eating even when we're full and other times turn down food completely? Why do we crave salty things at certain times, and sweets at other times?

31 Jan 2026