Immunology News and Research

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Immunology is the study of the body's immune system.

Advancing Immune Cell Research with the New FITdb Platform

Scientists at La Jolla Institute for Immunology (LJI) have developed a critical hub for functional genomics and immune cell research.

13 Nov 2026

Bioinformatic Analysis of 87 Vibrio Species Redefines Microbial Phylogenomics

The final-year project carried out by Alexandra García Flórez in the Department of Immunology, Microbiology and Parasitology of the University of the Basque Country-EHU has led to a scientific article being published in the prestigious journal Molecular Phylogenetics and Evolution.

5 Nov 2026

CRISPR Screen Uncovers COMPASS Pathway Role in Suppressing Gut Autoimmunity

Trillions of bacteria live in the human gut without triggering an immune response. Scientists at St. Jude Children's Research Hospital have now discovered a gene-regulatory pathway that helps maintain this delicate balance.

3 Nov 2026

Mitochondrial Iron Accumulation Drives Perforin Mediated Cancer Cell Death

For decades, scientists have known that a protein made by T cells and natural killer (NK) cells in the immune system, called perforin, can kill tumor cells by punching a hole in the cell wall and injecting proteases called granzymes, which kill the cell.

2 Nov 2026

UCLA Health Study Identifies Strategy to Boost Strength and Longevity of Cancer Fighting T Cells

Researchers at the UCLA Health Jonsson Comprehensive Cancer Center have identified a promising new strategy to make cancer-fighting immune cells stronger and potentially longer-lasting, a discovery that could help improve the effectiveness of immunotherapies that use a patient's own immune cells to attack cancer.

31 Oct 2026

Aberrant RNA Splicing Generates Immunogenic Neoantigens in Systemic Lupus

Scientists at La Jolla Institute for Immunology (LJI) and the University of Washington (UW) have discovered that patients with lupus have unusual mutations that may turn their bodies into battlegrounds.

30 Oct 2026

Evaxion Announces 89% Vaccine Target Precision and Sustained T-Cell and Clinical Responses at Three-Year Follow-Up in Phase 2 Trial with Personalized Cancer Vaccine EVX-01

Evaxion A/S, a clinical-stage TechBio company developing novel immunotherapies with its pioneering AI-Immunology™ platform, announces new three-year immune and clinical outcome data for personalized cancer vaccine EVX-01 in patients with advanced melanoma.

From Evaxion A/S 24 Oct 2026

INmune Bio Establishes Global Commercialization Framework for Ebstrocel™ Through Strategic Agreement with Uniphar

INmune Bio Inc. (the “Company”), a late-stage biotechnology company focused on inflammation and immunology, today announced that it has entered into a Master Services Agreement with Uniphar Durbin Ireland Limited (“Uniphar”) establishing a scalable framework to support international access, distribution and commercialization of Ebstrocel™, the Company’s allogeneic stromal cell therapy for Recessive Dystrophic Epidermolysis Bullosa (RDEB).

From INmune Bio 22 Oct 2026

Metabolic Reprogramming Enhances Gamma Delta CAR T Solid Tumor Clearance

By turning a patient's own immune cells into stronger cancer-fighting cells, CAR T-cell therapy has transformed how some blood cancers are treated. But it's been harder to extend this approach to solid tumors, including cancer that has spread to the bone.

21 Oct 2026

Novel Molecular Pathway Identified to Combat T-Cell Exhaustion in Cancer

Researchers at the UCLA Health Jonsson Comprehensive Cancer Center used a CRISPR screen to identify a key molecular pathway that drives exhaustion in cancer-fighting immune cells, limiting their ability to keep tumors under control.

16 Oct 2026

Food Allergy Risk Changes as Children Grow

Sensitization to food allergens can change considerably during the first five years of a child’s life. A large Canadian birth-cohort study shows that sensitization to peanut often develops early and persists, while sensitization to several tree nuts tends to appear later.

16 Oct 2026

Immunometabolic Reprogramming Strategy Addresses Chronic Inflammatory Conditions

Colorectal cancer has become the leading cause of cancer-related death for people under 50. Its most common forms generally aren't treatable, either through conventional means like chemotherapy or newer immunotherapy drugs.

16 Oct 2026

Study: Maternal Autoantibodies Targeting IL-1RA Trigger Premature Labor

A typical pregnancy lasts 40 weeks, but for about 1 in 10 pregnant women labor begins too soon. Premature or preterm birth is the leading cause of newborn deaths worldwide. Yet doctors have struggled to understand why preterm birth occurs - or how to predict which pregnancies are at highest risk.

15 Oct 2026

Transcriptional Repression Mechanism Prevents Protective Immune Pathways From Triggering Autoimmunity

A preclinical study by researchers at UT Southwestern Medical Center has discovered how a protein called ZBTB44 helps prevent excessive immune activity that can cause inflammation in the colon, the main section of the large intestine. The findings, published in Nature Immunology, may help explain how immune responses go awry in a range of chronic inflammatory and autoimmune diseases

13 Oct 2026

Study Creates Global Single-Cell Map of Human Immune System Aging

While birthday candles measure the number of years someone has lived, they don't always tell the full story about someone's health.

10 Oct 2026

Ancient Gut Microbes Traveled Globally With Prehistoric Human Ancestors

As waves of humans left Africa tens of thousands of years ago, eventually populating the entire planet, they were joined on their world-conquering ride by the trillions of microorganisms that compose the gut microbiome.

8 Oct 2026

Placental Microenvironment Reprograms Innate Immune Cells to Prevent Inflammation

In addition to their established role in fighting pathogens, certain maternal immune cells (neutrophils) can support early placental development by supporting placental cells migrate into the uterine lining.

6 Oct 2026

Novel Two-Dimensional Mapping Combines Generation Probability with Somatic Hypermutation

A research team led by Associate Professor Yohei Funakoshi, Associate Professor Kimikazu Yakushijin, and Professor Hironobu Minami of the Division of Medical Oncology/Hematology at Kobe University Hospital, together with Associate Professor Goh Ohji of the Division of Infectious Disease Therapeutics and Takaji Matsutani of Anymics Inc., has developed the pGen-SHM plot.

5 Oct 2026

Dr. GPCR and Eurofins Discovery Join Forces to Advance GPCR Drug Discovery

Dr. GPCR, the global knowledge hub for G protein-coupled receptor (GPCR) research and education, today announced a strategic partnership with Eurofins Discovery, the drug discovery services side of the same group behind the Eurofins DiscoverX products many in the community already know.

From Dr. GPCR 5 Oct 2026

Single-Cell Metabolic Profiling Identifies Key Bioenergetic Targets in Human Tumor Tissue

Immune cells can reach head and neck tumors, but once there, many stop functioning. This helps explain why immunotherapy with immune checkpoint inhibitors - which have transformed treatment for some cancers - benefit only 17%–23% of patients with head and neck squamous cell carcinoma. These are cancers that arise from cells lining the mouth, throat and voicebox.

1 Oct 2026

Immunology News and Research

Further Reading

Advancing Immune Cell Research with the New FITdb Platform

Bioinformatic Analysis of 87 Vibrio Species Redefines Microbial Phylogenomics

CRISPR Screen Uncovers COMPASS Pathway Role in Suppressing Gut Autoimmunity

Mitochondrial Iron Accumulation Drives Perforin Mediated Cancer Cell Death

UCLA Health Study Identifies Strategy to Boost Strength and Longevity of Cancer Fighting T Cells

Aberrant RNA Splicing Generates Immunogenic Neoantigens in Systemic Lupus

Evaxion Announces 89% Vaccine Target Precision and Sustained T-Cell and Clinical Responses at Three-Year Follow-Up in Phase 2 Trial with Personalized Cancer Vaccine EVX-01

INmune Bio Establishes Global Commercialization Framework for Ebstrocel™ Through Strategic Agreement with Uniphar

Metabolic Reprogramming Enhances Gamma Delta CAR T Solid Tumor Clearance

Novel Molecular Pathway Identified to Combat T-Cell Exhaustion in Cancer

Food Allergy Risk Changes as Children Grow

Immunometabolic Reprogramming Strategy Addresses Chronic Inflammatory Conditions

Study: Maternal Autoantibodies Targeting IL-1RA Trigger Premature Labor

Transcriptional Repression Mechanism Prevents Protective Immune Pathways From Triggering Autoimmunity

Study Creates Global Single-Cell Map of Human Immune System Aging

Ancient Gut Microbes Traveled Globally With Prehistoric Human Ancestors

Placental Microenvironment Reprograms Innate Immune Cells to Prevent Inflammation

Novel Two-Dimensional Mapping Combines Generation Probability with Somatic Hypermutation

Dr. GPCR and Eurofins Discovery Join Forces to Advance GPCR Drug Discovery

Single-Cell Metabolic Profiling Identifies Key Bioenergetic Targets in Human Tumor Tissue

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