Metabolism News and Research

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Metabolism is the means by which the body derives energy and synthesizes the other molecules it needs from the fats, carbohydrates and proteins we eat as food, by enzymatic reactions helped by minerals and vitamins.

Non-Dominant Bacterial Networks Drive Stability and Resilience in Gut Microbiome

The stability of the human gut microbiome relies on interactions between different bacterial species. However, the specific molecular mechanisms of these interactions, particularly among non-dominant species, remain largely unexplored.

16 Oct 2026

Gene Amplification Unexpectedly Increases Bacterial Susceptibility to Frontline Antibiotics

This study was led by Yuqin Song and Jie Feng from the Institute of Microbiology, Chinese Academy of Sciences. The researchers investigated how insertion sequence (IS)-mediated gene amplification contributes to the adaptability of Acinetobacter baumannii, an important nosocomial pathogen known for its multidrug resistance and persistence in clinical environments.

15 Oct 2026

Comprehensive Analysis of Emerging Strategies for Targeting Cyclin-Dependent Kinases in Cancer

More than 30 years after the direct connection was established between the molecular machinery controlling cell division and cancer, a new paper traces the evolution of cyclin-dependent kinase research and outlines the next generation of CDK-targeted therapies.

15 Oct 2026

Targeting Neural Chloride Homeostasis Mitigates Motor Deficits in Dystrophic Mice

DMD is a severe X-linked disorder caused by dystrophin deficiency and is characterized by progressive muscle degeneration and weakness.

14 Oct 2026

Study Challenges Traditional Nutrition Assumptions Regarding Equivalent Dietary Calorie Impacts

Most nutrition science suggests that meals with the same basic nutritional profile will have the same impact on a person's blood sugar.

13 Oct 2026

Retrotransposon Reactivation Suggests Reverse Transcriptase Inhibitors Lower Cancer Risk

A tumor suppressor gene known as p53 is mutated in more than half of all cancers, but how it acts to prevent cancer formation is largely unknown.

9 Oct 2026

Studies Redefine Lactation Biology Through Computational Multi-Omics and Mammary Metabolic Modeling

A study led by researchers at NYU Grossman School of Medicine identified shared molecular patterns in human milk that link maternal nutrition, mammary gland biology, and infant growth.

9 Oct 2026

Aldabra Giant Tortoise Genome Provides Evolutionary Blueprint for Cellular Resilience

Researchers studying a giant tortoise named Jonathan say it's not just good genes, but lack of genetic wear and tear that have kept him going for nearly two centuries.

8 Oct 2026

Integrated Multi-Omics Maps Metabolic Shift During Seed Development Stages

Canavalia gladiata, commonly known as sword bean, is a leguminous crop with high seed protein content (26%–30%) and oil rich in unsaturated fatty acids. Despite its nutritional promise, the species has remained underutilized, largely because a complete genome and the genetic basis of its nutritional traits were lacking.

8 Oct 2026

Obligate Endosymbionts Synthesize Vital Amino Acids and Nutrients for Host Survival

Endosymbionts are widely distributed across various cell types in insects and are transmitted primarily vertically, while also spreading among different hosts through horizontal transmission. Functionally, they can be divided into obligate (primary) and facultative (secondary) endosymbionts.

8 Oct 2026

Experts Extend Lives of Animals By Activating ‘Energy Saver’ Mode

The study, published today in Aging Cell, found strong evidence that triggering a protein governing energy level may help organisms live longer, in some cases by over 25%.

1 Oct 2026

Single-Cell Metabolic Profiling Identifies Key Bioenergetic Targets in Human Tumor Tissue

Immune cells can reach head and neck tumors, but once there, many stop functioning. This helps explain why immunotherapy with immune checkpoint inhibitors - which have transformed treatment for some cancers - benefit only 17%–23% of patients with head and neck squamous cell carcinoma. These are cancers that arise from cells lining the mouth, throat and voicebox.

1 Oct 2026

Kupffer Cells Increase Apolipoprotein Secretion in Response to Indigestible Plastics

Microplastics appear capable of significantly impairing the function of phagocytes in the liver, at least in mice. In turn, this disrupts the metabolism of this vital organ and increases the build-up of fat inside it. These are the key findings from a joint German-Austrian study led by the University of Bonn, details of which have now been published in the journal "Nature Metabolism."

1 Oct 2026

Gut-Derived Neutral Ceramidase Regulates MASH Through Microbial and Epithelial Signaling

Metabolic dysfunction-associated steatohepatitis (MASH) is often viewed through the lens of hepatic lipid accumulation, inflammation and fibrosis.

30 Sep 2026

Single-Cell Sequencing Confirms Epigenetic Remodeling Across Diverse Cardiac Cell Types

The adult human heart is a reliable and resilient engine fueling our everyday lives while also being responsive enough to supercharge a Usain Bolt sprint or sustain a three-week bike race in the French Alps and Pyrenees.

29 Sep 2026

Scientists Pinpoint the Brain Circuit That Regulates Metabolism

As the body’s temperature decreases, it compensates by utilizing additional energy to produce heat and stimulating the desire to eat to replenish the energy expended for warmth.

28 Sep 2026

Engineered 3D miBrains Model Human Neurovascular Units and Pathology

Mount Sinai researchers have identified how APOE4, the strongest genetic risk factor for Alzheimer's disease, damages the brain's blood vessels and promotes the buildup of abnormal proteins linked to neurodegenerative disease.

26 Sep 2026

Engineered E. coli Strains Validate Putrescine Uptake and Systemic Host Conversion

Gut microbiota influences multiple aspects of host physiology, including metabolic and immune functions. Many metabolites produced by gut bacteria can cross the intestinal epithelium (which the bacteria may not be able to cross) and enter host tissues, providing a pathway through which microbial activity can influence host physiology.

25 Sep 2026

3D Stem-Cell miBrains Model Complex Neurovascular Pathology in Human Tissue

25 Sep 2026

Cancer Cells Hijack Embryonic Repair Mechanisms to Seed Liver Metastases

Most colon cancer deaths are caused by the spread of tumor cells beyond the colon, usually to the liver. In a new study, MIT biologists identified a cellular pathway necessary for colorectal cancer metastasis.

25 Sep 2026

Metabolism News and Research

Non-Dominant Bacterial Networks Drive Stability and Resilience in Gut Microbiome

Gene Amplification Unexpectedly Increases Bacterial Susceptibility to Frontline Antibiotics

Comprehensive Analysis of Emerging Strategies for Targeting Cyclin-Dependent Kinases in Cancer

Targeting Neural Chloride Homeostasis Mitigates Motor Deficits in Dystrophic Mice

Study Challenges Traditional Nutrition Assumptions Regarding Equivalent Dietary Calorie Impacts

Retrotransposon Reactivation Suggests Reverse Transcriptase Inhibitors Lower Cancer Risk

Studies Redefine Lactation Biology Through Computational Multi-Omics and Mammary Metabolic Modeling

Aldabra Giant Tortoise Genome Provides Evolutionary Blueprint for Cellular Resilience

Integrated Multi-Omics Maps Metabolic Shift During Seed Development Stages

Obligate Endosymbionts Synthesize Vital Amino Acids and Nutrients for Host Survival

Experts Extend Lives of Animals By Activating ‘Energy Saver’ Mode

Single-Cell Metabolic Profiling Identifies Key Bioenergetic Targets in Human Tumor Tissue

Kupffer Cells Increase Apolipoprotein Secretion in Response to Indigestible Plastics

Gut-Derived Neutral Ceramidase Regulates MASH Through Microbial and Epithelial Signaling

Single-Cell Sequencing Confirms Epigenetic Remodeling Across Diverse Cardiac Cell Types

Scientists Pinpoint the Brain Circuit That Regulates Metabolism

Engineered 3D miBrains Model Human Neurovascular Units and Pathology

Engineered E. coli Strains Validate Putrescine Uptake and Systemic Host Conversion

3D Stem-Cell miBrains Model Complex Neurovascular Pathology in Human Tissue

Cancer Cells Hijack Embryonic Repair Mechanisms to Seed Liver Metastases

The Future of Vision Restoration With ReVision Implant

How a Single List Is Changing Visibility for Women in Science

How Avatar Medical's 3D Technology Is Transforming How We Visualize the Human Body

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