Metabolism News and Research

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Metabolism is the means by which the body derives energy and synthesizes the other molecules it needs from the fats, carbohydrates and proteins we eat as food, by enzymatic reactions helped by minerals and vitamins.

New Regulatory Pathway Enhances Key Aroma Compound in Wine Grapes

β-Damascenone is a key norisoprenoid compound responsible for characteristic floral and fruity aromas in grapes and wines, particularly those from non-aromatic varieties such as Cabernet Sauvignon and Merlot.

27 Nov 2025

Mitochondrial Mutation Found to Rewire Immune Function

Scientists have discovered how a mitochondrial mutation rewires immune function in a model of inherited primary mitochondrial disorders, which often lead to severe disability and death.

27 Nov 2025

Scientists Uncover Inner Workings of Biomolecular Condensates Linked to ALS

Inside the cell reside many tiny assembly factories and warehouses that gather together all of the proteins and RNAs-which carry out instructions from our DNA-that a living being needs.

27 Nov 2025

Discovery Reveals Unexpected Role for OTULIN in Controlling Tau Expression

Scientists have uncovered a surprising mechanism by which a brain enzyme called OTULIN controls the expression of tau, the protein that forms toxic tangles in Alzheimer's disease.

26 Nov 2025

Old Blood Stem Cells Regain Regenerative Capacity Through Lysosomal Intervention

Researchers at the Icahn School of Medicine at Mount Sinai have discovered how to reverse aging in blood-forming stem cells in mice by correcting defects in the stem cell's lysosomes.

25 Nov 2025

Senescent Blood Vessel Cells Drive the Development of Metabolic Disorders

Investigators from the Center for Advanced Gerotherapeutics at Cedars-Sinai found that aged blood vessel cells play a key role in the development of metabolic disorders, including diabetes.

24 Nov 2025

New Tool Maps Microbial Activity to Transform Gut Health Research

The gut microbiome is made up of trillions of microbes that play a vital role in keeping us healthy.  A disturbance in the balance of these microbes can contribute to a variety of health conditions, such as inflammatory bowel disease (IBD).

22 Nov 2025

Bacteriophages Facilitate the Survival of Lactic Acid Bacteria in Kimchi Fermentation

The World Institute of Kimchi (President: Hae Choon Chang), a government-funded research institute under the Ministry of Science and ICT, has confirmed in a new study that bacteriophages, which were previously considered a 'nuisance' during the process of food fermentation, actually play the role of key helpers that facilitate the survival of lactic acid bacteria (LAB).

21 Nov 2025

Cyanobacteria Change Their Genetic Activity After Sunset

Cyanobacteria, also referred to as blue-green algae, are found globally in diverse forms, encompassing both single-celled organisms and filamentous chains.

21 Nov 2025

Genetic Insights Reveal Key Drivers of Bone Density in Children

Researchers at Children's Hospital of Philadelphia (CHOP) revealed important genetic components that affect bone density in children and adolescents.

20 Nov 2025

Transcription Factor SmMYB53 Drives Enhanced Tanshinone Synthesis in Salvia miltiorrhiza

Salvia miltiorrhiza has long been used in traditional medicine, with tanshinones being its main active compounds.

19 Nov 2025

New Tool Studies Kinase Activity During DNA Damage

Cornell researchers have developed a powerful new biosensor that reveals, in unprecedented detail, how and where kinases – enzymes that control nearly all cellular processes – turn on and off inside living cells.

14 Nov 2025

Animals Evolved Similar Genetic Tools to Conquer Land Across Distant Lineages

Animals from completely different branches of the tree of life such as insects, worms and vertebrates independently evolved similar genetic solutions to survive on land, according to a new study from researchers at the University of Bristol and University of Barcelona.

13 Nov 2025

Dual Role of SlNOR and SlNOR-like1 Revealed in Tomato Pollen Development

Successful fertilization in flowering plants depends on healthy pollen development and structural integrity of the pollen wall.

10 Nov 2025

New Genetic Pathway Explains Why Some Citrus Fruits Taste Less Sour

The characteristic sour-sweet balance of citrus fruits is largely defined by citric acid accumulation in the vacuoles of juice sacs.

10 Nov 2025

Human Pangenome Research Opens a New Chapter in Precision Medicine

In May 2023, the Human Pangenome Reference Consortium (HPRC) released the first draft of the human pangenome reference sequence, which integrated genomic data from 47 individuals representing genetic diversity and added 119 million base pairs of euchromatic polymorphic sequences.

10 Nov 2025

St. Jude Scientists Discover Hidden Binding Pocket in Nuclear Receptors

A study from St. Jude Children's Research Hospital uncovered an alternative binding pocket within nuclear receptors, revealing a much-needed new therapy route for this important class of drug targets.

7 Nov 2025

Scientists Reveal Nonenzymatic Role of NUDT5 in Purine Pathway Regulation

Inside every cell, a finely tuned metabolic network determines when to build, recycle, or stop producing essential molecules.

7 Nov 2025

Ferroptosis Suppression Identified as a Key Driver of Lung Cancer Growth

NYU Langone Health researchers found that a type of cell death caused by a buildup of highly reactive molecules suppresses lung tumor growth.

6 Nov 2025

Study Unveils the Complete Biosynthetic Loop Regulating Tannin Production in Strawberries

Hydrolyzable tannins (HTs), including gallotannins and ellagitannins, are essential polyphenolic compounds that influence fruit taste, antioxidant capacity, and stress tolerance. Although condensed tannin biosynthesis has been well studied, the enzymatic processes governing HT formation remain unclear.

3 Nov 2025