Metabolism News and Research

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Metabolism is the means by which the body derives energy and synthesizes the other molecules it needs from the fats, carbohydrates and proteins we eat as food, by enzymatic reactions helped by minerals and vitamins.

Mutation in NAMPT Gene Found to Cause Rare Neurological Disease

An international research team, led by Shinghua Ding at the University of Missouri, has identified a previously unknown genetic disease that affects movement and muscle control.

28 Oct 2025

Discovery of Glucocorticoid Receptor Multimerization Opens Path to Safer Therapies

Drugs to treat inflammatory and autoimmune diseases - such as asthma, psoriasis, rheumatoid arthritis or Chrousos syndrome - act mainly through the glucocorticoid receptor (GR).

28 Oct 2025

TRF1 Knockout Mice Exhibit Healthier Metabolic States Without Telomere Shortening

A new research paper was published in Volume 17, Issue 9 of Aging-US on September 17, 2025, titled "Depletion of the TRF1 telomere-binding protein leads to leaner mice with altered metabolic profiles."

28 Oct 2025

First Chromosome-Scale Genome Assembly of Blackcurrant Reveals Drought Adaptation Strategies

Drought stress disrupts plant growth, metabolism, and reproduction, with devastating effects on crop productivity worldwide.

27 Oct 2025

Mitochondria and Lysosomes Orchestrate Metabolic States of Regulatory T Cells

Metabolism guides the activation states of regulatory T cells, the immune cells that prevent inappropriate activation of the immune system.

27 Oct 2025

Understanding Interplay of Physiological Processes as the Brain Shifts from Wakefulness to Sleep

Findings from Mass General Brigham investigators highlight the intricate interplay of diverse physiological processes as the brain shifts from wakefulness to sleep.

27 Oct 2025

RNA-Based Molecular Switch Enhances Disease Resistance in Pears

In recent years, scientists have uncovered the remarkable regulatory power of long non-coding RNAs (lncRNAs) - RNA molecules once dismissed as "genetic dark matter."

24 Oct 2025

Decoding the Genetic Network Behind Soybean Shade Tolerance

In intercropping systems, soybeans grown beneath tall maize plants experience severe shading that disrupts photosynthesis, weakens stems, and limits yield.

21 Oct 2025

Research Reveals Transcriptional Mechanism Behind Salt Tolerance in Watermelon

High soil salinity disrupts water absorption, ion balance, and photosynthesis in plants, leading to growth inhibition and yield loss.

16 Oct 2025

Revolutionary Technique Produces Trillions of Healthy Endothelial Cells

Scientists have discovered a method to induce human endothelial cells from a small biopsy sample to multiply in the laboratory, producing more than enough cells to replace damaged blood vessels or nourish organs for transplantation, according to a preclinical study by Weill Cornell Medicine investigators.

15 Oct 2025

Auxin Controls Grape Berry Firmness Through a Hierarchical Gene Cascade

Grape berry softening is a crucial physiological transition that affects postharvest storage, transport, and flavor.

15 Oct 2025

Acidic Tumor Environment Found to Rewire Cancer Cell Metabolism

Tumors are not a comfortable place to live: oxygen deficiency, nutrient scarcity, and the accumulation of sometimes harmful metabolic products constantly stress cancer cells.

10 Oct 2025

Living Biofilms Act as Natural Batteries to Degrade Antibiotics at Night

Researchers have unveiled a surprising new way that soil microbes can use sunlight energy - even after the lights go out.

8 Oct 2025

Intergenerational Transmission of Exercise Benefits Mediated by Sperm MicroRNAs

n a recent study published in Cell Metabolism, a collaborative research team led by Chen-Yu Zhang, Xi Chen, and Di-Jun Chen from Nanjing University, together with Tao Zhang from Nanjing Medical University, reported groundbreaking findings in their paper entitled "Paternal exercise confers endurance capacity to offspring through sperm microRNAs."

7 Oct 2025

EZH2 Inhibition Restores Order in Cancer Cell Division and Reduces Metastasis

Triple negative breast cancer (TNBC) is one of the most aggressive and hardest forms of breast cancer to treat, but a new study led by Weill Cornell Medicine suggests a surprising way to stop it from spreading.

6 Oct 2025

New Genetic Map of Human Metabolism Reveals How Genes Influence Health and Disease

A recent study published in Nature Genetics developed the largest genetic map of human metabolism, giving new insights into the role of metabolites in health and disease and providing a framework for future research.

6 Oct 2025

New Insights Into How Pathogens Build Protein Machinery for Survival in the Gut

A new study, led by researchers at the University of Liverpool, has revealed how pathogenic bacteria construct tiny protein-based compartments, known as Eut microcompartments, which enable them to digest ethanolamine - a nutrient commonly found in the gut.

3 Oct 2025