Metabolism News and Research

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Metabolism is the means by which the body derives energy and synthesizes the other molecules it needs from the fats, carbohydrates and proteins we eat as food, by enzymatic reactions helped by minerals and vitamins.

New Brain Atlas Reveals Molecular Dynamics of Prenatal Development

Scientists have long known that many developing brain cells originate in one region and migrate to another as they mature.

13 Nov 2026

Whole-Cell Simulation Reveals How Photosynthetic Bacteria Stabilize Fluctuating Energy

For some tiny microbes, access to light is essential for life. Organisms that convert light and carbon dioxide (CO₂) to the energy they need to live must continually adjust when light conditions change.

13 Nov 2026

Targeting lipA for Precise Management of Bacterial Outbreaks in Intensive Aquaculture

Bacterial diseases pose persistent challenges for intensive aquaculture, where outbreaks can damage fish health and cause substantial economic losses.

11 Nov 2026

Alveolar Macrophage Malfunction Discovered as a Primary Driver of Lung Disease

A new UCLA Health study in mice has identified a new potential trigger for pulmonary fibrosis: lipid dysregulation (a fat imbalance) within alveolar macrophages.

10 Nov 2026

KARAP Deficiency Enhances Macrophage IL-10 Production and Epithelial Barrier Repair

Ulcerative colitis (UC) is a chronic, relapsing inflammatory bowel disease in which persistent mucosal inflammation damages the epithelial barrier.

5 Nov 2026

Innate Immune Sensor cGAS Acts as Nuclear Metabolic Regulator

Scientists at the University of North Carolina Lineberger Comprehensive Cancer Center have discovered an unexpected role for a key innate immune protein, revealing how it helps regulate cholesterol levels inside cells and influences tumor growth and treatment response.

4 Nov 2026

Targeting the Blood-Brain Barrier Using Sodium-Dependent Multivitamin Transporter Protein Systems

Researchers at the University of Eastern Finland have identified a transporter protein with the potential to open new avenues for improving creatine delivery into the brain and for developing other therapies targeting the central nervous system.

31 Oct 2026

Dinosaur Blood – Oldest Discovery Rewrites What Fossils Can Reveal About the Past

An international research team led by Curtin University has for the first time uncovered unequivocal evidence of fossilized red blood cells and amino acids of collagen, fundamentally reshaping our understanding of fossil preservation and molecular longevity in deep time.

30 Oct 2026

Cytosolic Glucose and Mitochondrial Lactate Oxidation Prevent Energetic Collapse

The heart is the hardest-working muscle in the body, beating constantly no matter what the body’s energy reserves look like.

30 Oct 2026

A New Way to Watch Plants Respond to Disease in Real Time

Scientists at the MRC Laboratory of Medical Sciences (LMS) have devised a novel method for improving the accuracy of luminescent biological reporters, which enables researchers to monitor gene expression in living plants for extended periods, including days, weeks, and potentially months or even years.

26 Oct 2026

Taurine Deficiency Triggers Innate Immune Sensing of Cellular Danger Signals

Sustained low-level inflammation is a hallmark of the aging process. The accumulating damage persistently activates the innate immune system-the body's first line of defense-leading to what is known as inflammaging, functional decline and chronic diseases of old age.

26 Oct 2026

BioUK Awards 2026 Celebrate Outstanding Achievement and Breakthrough Innovations from Across the Life Sciences

BioUK, the not-for-profit membership organization focused on catalyzing success in UK life sciences, today announced the winners of the 18th annual BioUK Awards following a ceremony hosted at the Royal Lancaster Hotel, London.

From BioUK 23 Oct 2026

Promega UK Launches Lumit® Insulin Immunoassay

A new homogeneous, wash-free, plate-based assay that enables researchers to rapidly measure insulin secretion using a simple add-and-read format, delivering robust results ideal for metabolic disease drug discovery.

From Promega Corporation 22 Oct 2026

Metabolic Reprogramming Enhances Gamma Delta CAR T Solid Tumor Clearance

By turning a patient's own immune cells into stronger cancer-fighting cells, CAR T-cell therapy has transformed how some blood cancers are treated. But it's been harder to extend this approach to solid tumors, including cancer that has spread to the bone.

21 Oct 2026

Stable Isotope Carbon Tracing Proves Uncoupling Inhibits De Novo Purine Synthesis

Mitochondrial serine catabolic pathway (MSCP), also called serine, glycine, and one-carbon metabolism, is essential for cancer cells to produce amino acids, one-carbon units, and reducing equivalents.

20 Oct 2026

Non-Dominant Bacterial Networks Drive Stability and Resilience in Gut Microbiome

The stability of the human gut microbiome relies on interactions between different bacterial species. However, the specific molecular mechanisms of these interactions, particularly among non-dominant species, remain largely unexplored.

16 Oct 2026

Gene Amplification Unexpectedly Increases Bacterial Susceptibility to Frontline Antibiotics

This study was led by Yuqin Song and Jie Feng from the Institute of Microbiology, Chinese Academy of Sciences. The researchers investigated how insertion sequence (IS)-mediated gene amplification contributes to the adaptability of Acinetobacter baumannii, an important nosocomial pathogen known for its multidrug resistance and persistence in clinical environments.

15 Oct 2026

Comprehensive Analysis of Emerging Strategies for Targeting Cyclin-Dependent Kinases in Cancer

More than 30 years after the direct connection was established between the molecular machinery controlling cell division and cancer, a new paper traces the evolution of cyclin-dependent kinase research and outlines the next generation of CDK-targeted therapies.

15 Oct 2026

Targeting Neural Chloride Homeostasis Mitigates Motor Deficits in Dystrophic Mice

DMD is a severe X-linked disorder caused by dystrophin deficiency and is characterized by progressive muscle degeneration and weakness.

14 Oct 2026

Study Challenges Traditional Nutrition Assumptions Regarding Equivalent Dietary Calorie Impacts

Most nutrition science suggests that meals with the same basic nutritional profile will have the same impact on a person's blood sugar.

13 Oct 2026