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Hidden Role of Biliverdin Reductase A in Fighting Oxidative Damage

According to a new study from Johns Hopkins Medicine, the enzyme biliverdin reductase A (BVRA) protects neurons directly from oxidative stress, regardless of whether it produces the yellow pigment bilirubin.

5 Nov 2025

Enzyme BVRA Found to Shield Neurons from Oxidative Stress

New research from Johns Hopkins Medicine shows that the enzyme biliverdin reductase A (BVRA) plays a direct protective role against oxidative stress in neurons, independent of its role producing the yellow pigment bilirubin.

4 Nov 2025

TUM Researchers Discover Molecular Switch Controlling Programmed Cell Death

In the fight against disease, programmed cell death – also known as apoptosis – is a key protective function of the body.

4 Nov 2025

Researchers Use Bacterium’s Own Defenses to Amplify Antibiotic Power

Scientists at St. Jude Children's Research Hospital have found a way to use a bacterium's own drug resistance mechanisms against itself, presenting a potentially safer and more effective way to treat certain antibiotic-resistant infections.

3 Nov 2025

How Leucine Boosts Cellular Energy Production

Researchers at the University of Cologne have found that a particular dietary amino acid enhances cellular energy, thereby creating new opportunities for the treatment of metabolic disorders.

3 Nov 2025

Mitochondria and Lysosomes Orchestrate Metabolic States of Regulatory T Cells

Metabolism guides the activation states of regulatory T cells, the immune cells that prevent inappropriate activation of the immune system.

27 Oct 2025

Breakthrough Research Uncovers Dual Role of Enzymes in Prostate Cancer

A major international study has uncovered a new vulnerability in prostate cancer cells that could help improve treatment for one of the most common cancers affecting men.

15 Oct 2025

Acidic Tumor Environment Found to Rewire Cancer Cell Metabolism

Tumors are not a comfortable place to live: oxygen deficiency, nutrient scarcity, and the accumulation of sometimes harmful metabolic products constantly stress cancer cells.

10 Oct 2025

Human Kidney Organoids Offer New Insights into APOL1-Mediated Kidney Disease

Chronic kidney disease (CKD) impacts over 700 million individuals globally and arises from a combination of genetic and environmental influences, along with pre-existing health conditions.

3 Oct 2025

Astrocytes Found to Integrate Signals from Multiple Neurons

A collaborative French-Swiss study reveals a previously unknown role for astrocytes in the brain's information processing.

25 Sep 2025

Reconstructing Human Mitochondrial Transcription in Unprecedented Detail

Aging, neurological diseases and our bodies' stress response are all linked to the tiny power plants inside each cell known as mitochondria.

17 Sep 2025

Microbial Molecule Controls Cancer Progression and Boosts Chemotherapy

An international team of scientists led by researchers from the MRC Laboratory of Medical Sciences (LMS), Imperial College London, and the University of Cologne discovered that microbes associated with tumors produce a molecule that can control cancer progression and improve chemotherapy efficacy.

15 Sep 2025

Scientists Identify Human Proteins Essential for SARS-CoV-2 Infection and Replication

Despite vaccines and treatments, SARS-CoV-2-the virus that causes COVID-19-continues to pose a global health threat, driven by new variants and its ability to hijack human cells in ways that still aren't fully understood.

5 Sep 2025

Tumors Use Mitochondrial Transfer to Reprogram Surrounding Cells

Tumors have developed many strategies and tricks to gain advantages in the body. Led by cell biology professor Sabine Werner, researchers at ETH Zurich have now discovered another surprising trick that certain tumors resort to in ensuring their survival and growth.

1 Sep 2025

New Method Enables Human Cells to Initiate Meiosis Outside the Body

More than one-sixth of adults around the world experience infertility in their lifetime. There is a high unmet need not only for increased access to affordable, high-quality fertility care for those in need but, importantly, also for new biomedical solutions that can address the root causes of infertility.

18 Aug 2025