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Study Reveals New Biological Pathway for TNF-Resistant Crohn’s Disease

Mayo Clinic researchers have identified an immune-regulating molecule that may help explain why some patients with inflammatory bowel disease (IBD), including Crohn's disease and ulcerative colitis, do not respond to commonly used therapies.

14 May 2026

Prime Assembly Enables Precise Insertion of Large DNA Segments Into the Genome

Researchers at UMass Chan Medical School have developed a gene editing technology that allows for the precise and efficient insertion of very large DNA segments into the human genome.

13 May 2026

Inherited Genetic Pathways Shape Individual Cancer Risk and Outcomes

Why do two people with the same cancer diagnosis-the same stage, the same cell type, and the same clinical profile-often have completely different outcomes? For decades, scientists have studied acquired mutations in cancer to find answers, but mutations alone explain only part of the story.

12 May 2026

Epigenetic Changes May Influence Inheritance Beyond DNA Sequence Alone

When we think about genetic inheritance, we usually leap to DNA, the four-letter code containing the instructions for building a living organism.

11 May 2026

DNA Study Reveals the Personal Pathways Behind Different Tumors

Why do two individuals with the identical cancer diagnosis—the same cell type, the same stage, and the same clinical profile—often experience very different outcomes? Scientists have been researching acquired mutations in cancer for decades in an effort to uncover solutions, but mutations by themselves only account for a part of the problem.

11 May 2026

New Analysis Uncovers Evolutionary Adaptations Within Human Gut Bacteria

The human gut harbors a complex ecosystem of trillions of microorganisms (the microbiome), which influences digestion, the immune system and metabolism.

8 May 2026

New CRISPR System Destroys Diseased Cells With High Precision

A new kind of CRISPR that destroys cells rather than gene editing them has shown potential for killing sick cells while leaving healthy cells untouched.

8 May 2026

Interactions Across the Genome Drive Neurodevelopmental Risks

People who have the same deletion of a section of chromosome 16 are susceptible to neurodevelopmental disorders; however, some may simply show moderate psychological symptoms like anxiety or depression, while others may have significant intellectual disability or developmental delay.

6 May 2026

AI Model Reads DNA Like Language to Trace Ancestry

Researchers at the University of Oregon have developed an artificial intelligence tool that can read genetic code the way large language models like ChatGPT read text. Scanning the genome for biological mutation patterns, the computer model traces pairs of genes back in time to their last common ancestor.

5 May 2026

Engineered Bacteriophage Speeds up the "Training" of Plastic-Eating Bacteria

Millions of tons of plastic waste build up in landfills and oceans each year. One promising approach is to engineer microbes to break plastic down into useful chemical building blocks.

4 May 2026

Prime Assembly Approach Transforms Gene Therapy With Large DNA Inserts

New technology enables the insertion of a large segment of DNA into a genome, potentially expanding gene therapy treatment from cancellation of disease-causing mutations to replacement of an entire gene, scientists say.

30 Apr 2026

How the Microbiome Shapes Cancer Immunity and Therapy Response

This review examines how the human microbiome regulates anti-tumor immunity through DNA damage, inflammation, immune-cell activity, microbial metabolites, and tumor microenvironment remodeling. It highlights emerging microbiome-based strategies, including FMT, probiotics, prebiotics, engineered bacteria, and live biotherapeutics, while stressing the need for rigorous validation and clinical trials.

29 Apr 2026

New Data Demonstrates the Unique Scalability of Evaxion’s AI-Immunology™ Platform in Glioblastoma

Evaxion A/S (“Evaxion”), a clinical-stage TechBio company developing novel vaccines with its pioneering AI-Immunology™ platform, announces new data demonstrating the platform’s ability to also potentially develop vaccines for glioblastoma (brain cancer).

From Evaxion A/S 21 Apr 2026

Gene Editing Reprograms Immune System to Produce Therapeutic Proteins

An innovative gene-editing strategy could establish a new way for the body to manufacture therapeutic proteins-including certain kinds of highly potent antibodies the are naturally difficult to produce-by reprogramming the immune system itself.

20 Apr 2026

New Technology Tracks Real-Time Gene Activity to Find Common Disease Targets

Diseases like cancer or neurodegeneration are known to arise from genetic misfires. But treating such complex conditions hasn't been simply a matter of identifying the malfunctioning genes involved. With hundreds of genetic mutations spanning diverse pathways at play, connecting the dots between a constellation of mutations and a specific outcome has proved to be enormously difficult.

16 Apr 2026