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Cheesemaking Inspires New Insights into Fungal Evolution and Food Security

Many scientific discoveries are serendipitous-the result of chance. Seeing evolution in action in a cheese cave turned out to be exactly that for Benjamin Wolfe, associate professor of biology, and his colleagues.

15 Sep 2025

Engineered Base Editor Corrects ACTA2 Mutation in Rare Childhood Disease

Multisystemic smooth muscle dysfunction syndrome (MSMDS) is a rare condition associated with stroke, aortic dissection (tearing) and death in childhood.

13 Sep 2025

Blocking SUMO2 Protein may be a Winning Strategy Against Synovial Sarcoma

In the sport of sumo, a bout most commonly ends when one competitor is pushed or thrown outside of a ring of straw bales partially buried in clay.

8 Sep 2025

Scientists Identify Human Proteins Essential for SARS-CoV-2 Infection and Replication

Despite vaccines and treatments, SARS-CoV-2-the virus that causes COVID-19-continues to pose a global health threat, driven by new variants and its ability to hijack human cells in ways that still aren't fully understood.

5 Sep 2025

Tackling KRAS Mutations Unlocks New Hope for Pancreatic Cancer Patients

Accounting for nearly 90% of all pancreatic cancers, pancreatic ductal adenocarcinoma (PDAC) has a five-year survival rate of just 13%. Late-stage diagnosis, limited surgical options, and toxic chemotherapy regimens contribute to its poor outcomes.

2 Sep 2025

RNA Binding Proteins and EVs Offer Clues to Cancer's Evasion of Immune Response

Certain types of biochemical processes can impair the immune system's ability to recognize and kill cancer cells. Purdue University's W. Andy Tao and his associates have developed a new way to study these processes.

27 Aug 2025

New Insights Reveal Bacterial Roots of Key Plant Hormone Enzymes

Terpenoids play vital roles in plant ecology-from repelling pests to attracting pollinators-and are produced by terpene synthases (TPSs) enzymes.

19 Aug 2025

New Enzyme Technology Illuminates Hidden Sugar Patterns on Cells

Sugars known as glycans form dense envelopes around cells. But they're often ignored in biological investigations because, unlike DNA, proteins and other cellular components, tools to study them are lacking.

18 Aug 2025

Smaller Scale Mutations in HNF1A Gene Nudge Millions Toward Type-2 Diabetes

Mutations in a single gene, HNF1A, are known to cause MODY3, a rare, early onset form of diabetes.

7 Aug 2025

Parkinson’s Gene Mutation Blocks Vital Neuroprotective Signals

GBA1 mutations impair ciliary Hedgehog signaling in Parkinson's disease, reducing neuroprotective factors and highlighting a shared pathogenic pathway.

7 Aug 2025

Case Western Researchers Use Stem Cells to “Shut Off” Nerve Cell Strain

Amyotrophic lateral sclerosis (ALS), sometimes known as Lou Gehrig’s disease, is an incurable neurological disease that affects motor neurons, which are nerve cells in the brain and spinal cord that regulate voluntary muscle movement and breathing.

6 Aug 2025

Prime Editing Reverses Symptoms of Severe Childhood Neurological Disease

Scientists use a precise form of gene editing called prime editing to correct the most common genetic mutations that cause alternating hemiplegia of childhood, a rare and severe neurological disorder that begins in infancy.

From The Jackson Labs 6 Aug 2025

Advanced Genetic Analysis with the epicGEN Solid Cancer and MSI Kit

Highly sensitive and efficient analysis with an emphasis on specific regions of the genome. epicGEN NGS panels are designed for modern diagnostic laboratories.

29 Jul 2025

Improved Agrobacterium Strains Enhance Plant Genetic Engineering Efficiency

These mutations improve biocontainment, transformation stability, and overall performance in genetic engineering of plants.

22 Jul 2025

Gene Editing Reverses Symptoms of Rare Brain Disorder in Mice

Scientists have corrected gene mutations in mice causing an ultra-rare disease by editing DNA directly in the brain with a single injection, a feat with profound implications for patients with neurological diseases.

22 Jul 2025

Immune Cells Use Central Actin Structures to Squeeze Through Tight Spaces

Immune responses rely on the efficient movement of immune cells within the complex and geometrically unpredictable three-dimensional tissues that make up our bodies.

22 Jul 2025

Study Reveals Surprising Redundancy in Staph Metabolism

In the ongoing battle against antibiotic-resistant bacteria, MSU researchers have made a discovery that could reshape how we target deadly pathogens like staph infections.

17 Jul 2025

Microglia Replacement Halts Progression of Fatal Neurological Disease in Mice and Humans

Adult-onset leukoencephalopathy with axonal spheroids and pigmented glia (ALSP) is a progressive neurological disease with an average age of onset of 43 years and an average life expectancy of only 3 to 5 years after symptoms begin.

11 Jul 2025

Small Genetic Change in Humans Weakens Immune Attack on Solid Tumors

New research from UC Davis Comprehensive Cancer Center has uncovered an evolutionary change that may explain why certain immune cells in humans are less effective at fighting solid tumors compared to non-human primates.

4 Jul 2025

Combining AI with Robotics and Synthetic Biology to Improve Industrial Enzymes

By combining artificial intelligence with automated robotics and synthetic biology, researchers at the University of Illinois Urbana-Champaign have dramatically improved performance of two important industrial enzymes - and created a user-friendly, fast process to improve many more.

2 Jul 2025