Nucleotide News and Research

RSS

Revive Penicillin’s Power by Exploiting Bacteria’s Hidden Weakness

When many disease-causing bacteria come into contact with penicillin, they do not necessarily die immediately, but instead enter a brief survival mode known as antibiotic tolerance.

13 Mar 2026

Transposable Elements Found Responsible for Most Lethal Fly Mutations

Most lethal mutations in wild fruit flies are driven by newly transferred jumping genes, not small DNA errors, according to a new study from Duke University.

11 Mar 2026

Genetic Analysis Uncovers Shared Biology Across Major Psychiatric Conditions

Although mental disorders have multifactorial causes, genetics can explain some of them, yet this field remains largely unexplored in terms of guiding diagnoses and treatments.

10 Mar 2026

Whole-Cell Simulation Recreates Molecular Dynamics of Minimal Living Cell

By simulating the life cycle of a minimal bacterial cell - from DNA replication to protein translation to metabolism and cell division - scientists have opened a new frontier of computer vision into the essential processes of life.

10 Mar 2026

Large-Scale Study Maps DNA Variants Shaping Human Disease Risk

Scientists have identified how specific genetic changes function in cells to influence disease risk and other human health traits.

26 Feb 2026

5,000-Year-Old Cave Bacterium Resists Antibiotics and Kills Pathogens

Psychrobacter SC65A.3, preserved in cave ice, harbors multidrug resistance genes and exhibits antimicrobial activity, offering insights into ancient resistomes.

26 Feb 2026

Scientists Map Protein Production Across Individual Brain Cells

The brain's ability to do everything from forming memories to coordinating movement relies on its cells producing the right proteins at the right time.

19 Feb 2026

Uncoupling Nucleotide Synthesis: A Yeast-Derived Solution for Mitochondrial Disease

Nucleotide synthesis-the production of the basic components of DNA and RNA-is essential for cell growth and division.

17 Feb 2026

Genome Skimming Resolves Clematis Evolutionary Relationships

Known as the "Queen of Climbers," the genus Clematis boasts over 300 species widely distributed across the globe.

11 Feb 2026

Ancestry-Specific Genetic Models Advance Breast Cancer Risk Assessment

Despite major advances in genetic testing for breast cancer risk prediction, death rates remain disproportionately high among women of African ancestry.

4 Feb 2026

Single Enzyme Enables Low-Cost Synthesis of All RNA Nucleotides

A single enzyme that can generate all four nucleotide triphosphates, the building blocks of ribonucleic acid (RNA), was identified by researchers at the Institute of Science Tokyo.

24 Jan 2026

Researchers Elucidate Microtubule-Mediated Cell Signal Transduction

The most diverse functions of a cell in the human body – from cell division and differentiation to motility and programmed cell death – are controlled by signaling proteins within the cell. This includes the immune system and the reading of genetic information.

11 Dec 2025

Circular Single-Stranded DNA Molecule Can Simultaneously Silence Multiple MicroRNAs

Professor Dongsheng Liu of Tsinghua University, Professor Ziyang Hao of Capital Medical University, and Researcher Yuanchen Dong of the Institute of Chemistry, Chinese Academy of Sciences, have collaborated to develop a circular single-stranded DNA molecule capable of simultaneously silencing multiple miRNAs.

4 Dec 2025

Ambiguous Stop Codons Expand the Genetic Code in Archaea

The beauty of the DNA code is that organisms interpret it unambiguously. Each three-letter nucleotide sequence, or codon, in a gene codes for a unique amino acid that's added to a chain of amino acids to make a protein.

2 Dec 2025

Genetic Analysis Uncovers Six Distinct Lineages of Global Tea Germplasm

Using 150 single-nucleotide polymorphism (SNP) markers across 252 tea accessions from India and China, researchers identified six major genetic groups, including the small-leafed sinensis and five broadleaf assamica populations from India, Indochina, and Yunnan. The

22 Nov 2025

Targeted Genetic Testing Revolutionizes Diagnosis of X-Linked Dystonia-Parkinsonism

Scientists at Brigham and Women's Hospital and Harvard Medical School have developed a targeted genetic test to improve diagnosis for X-linked dystonia-parkinsonism (XDP), a rare and disabling movement disorder that affects primarily men of Filipino ancestry.

17 Nov 2025