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Scientists Find Key Genetic Boundary That Dictates Immune System Failure

Not all broken genes fail in the same way: some simply stop working, while others interfere with what still works.

22 May 2026

Cryo-EM Images Reveal Coronavirus Proofreading Enzyme in Atomic Detail

The closest-ever detailed look at a key enzyme inside the virus that causes COVID-19 could lead to more effective treatment of the disease.

8 May 2026

Genomic Tool TRACS Improves Tracking of Microbial Transmission Patterns

The research, published today (24 April) in Nature Microbiology, describes how the new tool, called TRAnsmision Clustering of Strains (TRACS), uses genomics to distinguish between closely related bacterial strains.

4 May 2026

New Pipeline Sharpens Single-Cell Profiling of CAR Immune Therapies

CERTOMICS is a Nextflow-based computational pipeline designed to identify and profile CAR-engineered immune cells using single-cell multiomics data. By integrating gene expression, immune receptor profiling, protein markers, CAR-aware references, and CAR-specific quality control, it supports more standardized analysis of adoptive cellular immunotherapies.

29 Apr 2026

High Resolution Images Reveal DNA Repair Process in Key Protein

Scientists have captured the most detailed structural images to date of a specific type of protein's DNA repair process, a finding that could reveal ways to inhibit the effects of BRCA1 and BRCA2 mutations that heighten the risk for breast, ovarian and other cancers.

28 Apr 2026

1,116 Genomes Mapped to Reveal Hidden Human DNA Variation

The 1KCP pangenome enhances genetic research by mapping diverse DNA variations, crucial for understanding disease risk and advancing population genetics.

16 Apr 2026

Excessive RNA Editing May Explain Neurological Differences in Down Syndrome

A collaborative research study co-led by scientists at the Icahn School of Medicine at Mount Sinai and the Liber Institute for Brain Development has for the first time identified a biological process that may help explain how the brain develops differently in people with Down syndrome. The study was a collaboration among scientists from the Icahn School of Medicine at Mount Sinai, the Lieber Institute for Brain Development, the Medical University of Sofia in Bulgaria, and the University of Arizona.

2 Apr 2026

Revive Penicillin’s Power by Exploiting Bacteria’s Hidden Weakness

When many disease-causing bacteria come into contact with penicillin, they do not necessarily die immediately, but instead enter a brief survival mode known as antibiotic tolerance.

13 Mar 2026

Transposable Elements Found Responsible for Most Lethal Fly Mutations

Most lethal mutations in wild fruit flies are driven by newly transferred jumping genes, not small DNA errors, according to a new study from Duke University.

11 Mar 2026

Genetic Analysis Uncovers Shared Biology Across Major Psychiatric Conditions

Although mental disorders have multifactorial causes, genetics can explain some of them, yet this field remains largely unexplored in terms of guiding diagnoses and treatments.

10 Mar 2026

Whole-Cell Simulation Recreates Molecular Dynamics of Minimal Living Cell

By simulating the life cycle of a minimal bacterial cell - from DNA replication to protein translation to metabolism and cell division - scientists have opened a new frontier of computer vision into the essential processes of life.

10 Mar 2026

Large-Scale Study Maps DNA Variants Shaping Human Disease Risk

Scientists have identified how specific genetic changes function in cells to influence disease risk and other human health traits.

26 Feb 2026

5,000-Year-Old Cave Bacterium Resists Antibiotics and Kills Pathogens

Psychrobacter SC65A.3, preserved in cave ice, harbors multidrug resistance genes and exhibits antimicrobial activity, offering insights into ancient resistomes.

26 Feb 2026

Scientists Map Protein Production Across Individual Brain Cells

The brain's ability to do everything from forming memories to coordinating movement relies on its cells producing the right proteins at the right time.

19 Feb 2026

Uncoupling Nucleotide Synthesis: A Yeast-Derived Solution for Mitochondrial Disease

Nucleotide synthesis-the production of the basic components of DNA and RNA-is essential for cell growth and division.

17 Feb 2026

Genome Skimming Resolves Clematis Evolutionary Relationships

Known as the "Queen of Climbers," the genus Clematis boasts over 300 species widely distributed across the globe.

11 Feb 2026

Ancestry-Specific Genetic Models Advance Breast Cancer Risk Assessment

Despite major advances in genetic testing for breast cancer risk prediction, death rates remain disproportionately high among women of African ancestry.

4 Feb 2026

Single Enzyme Enables Low-Cost Synthesis of All RNA Nucleotides

A single enzyme that can generate all four nucleotide triphosphates, the building blocks of ribonucleic acid (RNA), was identified by researchers at the Institute of Science Tokyo.

24 Jan 2026

Researchers Elucidate Microtubule-Mediated Cell Signal Transduction

The most diverse functions of a cell in the human body – from cell division and differentiation to motility and programmed cell death – are controlled by signaling proteins within the cell. This includes the immune system and the reading of genetic information.

11 Dec 2025

Circular Single-Stranded DNA Molecule Can Simultaneously Silence Multiple MicroRNAs

Professor Dongsheng Liu of Tsinghua University, Professor Ziyang Hao of Capital Medical University, and Researcher Yuanchen Dong of the Institute of Chemistry, Chinese Academy of Sciences, have collaborated to develop a circular single-stranded DNA molecule capable of simultaneously silencing multiple miRNAs.

4 Dec 2025