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Novel ENDOtollins Block Harmful Inflammation While Preserving Infection Response

Scripps Research scientists have developed a new class of drug compounds that reduce harmful inflammation while leaving the body's ability to fight infections intact-a long-sought goal in treating autoimmune diseases.

7 Apr 2026

Genomic Study Reveals How Bacterial ‘Armor’ Reduces Cholera Disease Severity

Cholera-causing bacteria are locked in an evolutionary arms race with a viral nemesis, according to a new genomic study.

2 Apr 2026

Cysteine Pathways Shape T Cell Expansion and Cancer Defense

A research team from the Johns Hopkins Kimmel Cancer Center, its Bloomberg~Kimmel Institute for Cancer Immunotherapy and the Johns Hopkins Bloomberg School of Public Health have discovered how the immune system's CD8+ T cells use the nutrient cysteine to control two essential functions that compete for this resource - the immune cell's ability to multiply and its ability to kill cancer cells.

1 Apr 2026

Tick-Borne Parasite Treatment Benefits From Replacing Infected Red Cells

In a multicenter study, researchers at Mass General Brigham found that exchange transfusion was associated with markedly improved outcomes compared with standard treatment for a potentially life-threatening tick-borne infection

31 Mar 2026

New Technology Enables Whole-Body Analysis of Gene Expression

Understanding gene expression within the body has been a boon for 21st century biology and therapeutics, but most discoveries that use these technologies only focus on one organ or one small area of tissue.

30 Mar 2026

Genetic Study Reveals Insecticide Resistance in Malaria Vector Mosquitoes

Anopheles darlingi mosquitoes-a major vector of malaria in South America-are evolving in response to insecticides, which may make them harder to kill and malaria more difficult to control, according to a new study led by Harvard T.H. Chan School of Public Health.

28 Mar 2026

Novel Phage W5 Offers a Sustainable Solution for Foodborne Salmonella

Researchers from China have identified a novel bacteriophage that offers a highly promising "green" biocontrol solution against foodborne Salmonella.

27 Mar 2026

Phenolic Contaminants Drive Selective Radical Pathways for Antibiotic Degradation

Emerging contaminants such as antibiotics and persistent organic pollutants increasingly threaten global water security and public health.

13 Mar 2026

Tirzepatide Reduces Alcohol Drinking And Relapse In Preclinical Study

Tirzepatide alters brain reward signaling and reduces alcohol intake in rodents, indicating its potential as a therapeutic option for alcohol use disorder.

4 Mar 2026

Hutton Scientists Develop New Test for Fecal Contamination Which Cuts Time for Results From 24 Hours to Four

Scientists at The James Hutton Institute, Scotland’s pre-eminent interdisciplinary scientific research institute for the sustainable management of land, crop and nature resources, have developed a new test that reduces the time required to analyze water samples for indicators of fecal contamination from 24 hours to four.

24 Feb 2026

Small RNAs in the Sperm Guide the Earliest Stages of Embryonic Development

Mounting evidence from research on nematodes to mice indicate that a father's environment, such as what he eats or if he is exposed to stress or toxicants, can lead to metabolic and behavioral disorders in his offspring.

20 Feb 2026

Study Reveals Planet-Wide Network of Interconnected Microbiomes

In a new study published in Cell, scientists in the Bork Group at EMBL Heidelberg reveal that microbes living in similar habitats are more alike than those simply inhabiting the same geographical region.

10 Feb 2026

Ancestry-Specific Genetic Models Advance Breast Cancer Risk Assessment

Despite major advances in genetic testing for breast cancer risk prediction, death rates remain disproportionately high among women of African ancestry.

4 Feb 2026

ER-Phagy: A Novel Target for Age-Related Diseases

Improvements in public health have allowed humankind to survive to older ages than ever before, but, for many people, these added golden years are not spent in good health.

4 Feb 2026

Bacteria's Hidden Communication Network Drives Drug Resistance

Biologists have uncovered a new mode of communication inside cells that helps bacterial pathogens learn how to evade drugs.

2 Feb 2026

Protein Translation Enzyme Governs Macrophage Maturation and Tissue Homeostasis

A new study led by researchers at the Johns Hopkins Kimmel Cancer Center, its Bloomberg~Kimmel Institute for Cancer Immunotherapy and the Johns Hopkins Bloomberg School of Public Health found that an enzyme involved in protein translation is essential for circulating immune cells, called monocytes, to mature into tissue-resident macrophages, a specialized population of immune cells that maintain organ health by clearing dead cells and debris.

24 Jan 2026

DHPS Enzyme Deficiency Impairs Macrophage Development and Tissue Repair

22 Jan 2026

First Fully Synthetic Bacteriophage Engineering System for Antibiotic-Resistant Bacterium

Bacteriophages have been used therapeutically to treat infectious bacterial diseases for over a century.

21 Jan 2026

Asexual Parasite's Host-Switching Strategy: A Short-Term Evolutionary Win

Australian researchers have uncovered how a particular strain of a diarrhea-causing parasite managed to infect more animal species, offering new insights into how parasitic infections emerge and spread to people.

7 Jan 2026

Machine Learning Models Identify Early Metabolic Shifts

Acute systemic inflammation has long been suspected to trigger harmful processes within the brain, contributing to neurodegenerative disorders such as Alzheimer's and Parkinson's disease. A new study published online in the Journal of Proteome Research on November 30, 2025, led by Professor Kei Zaitsu from the Faculty of Biology-Oriented Science and Technology, Kindai University, Japan, now provides compelling evidence that such inflammation causes region-specific metabolic disruption, identifying biochemical pathways that fail during the early stages of neuroinflammation.

22 Dec 2025