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UNC Researcher Wins Mathers Foundation Grant to Study T-Cell Metabolism

Jessica Thaxton, PhD, MsCR, associate professor in the Department of Cell Biology and Physiology at the UNC School of Medicine and co-leader of the Cancer Cell Biology Research Program at UNC Lineberger Comprehensive Cancer Center, has been awarded a prestigious $700,000 grant from the Mathers Foundation to support research into the role of the endoplasmic reticulum in T-cell metabolism and cancer development.

2 Sep 2026

Protein Interaction Helps Senescent Cells Survive Aging and Cellular Stress

Senescent cells - cells that have stopped dividing but remain metabolically active - can accumulate with age and contribute to chronic inflammation and tissue dysfunction

2 Sep 2026

Targeting EFHD1 Protein Prevents Severe Obesity-Related Metabolic Liver Damage

Obesity-related metabolic liver disease affects hundreds of millions of people worldwide, but only some fraction of those livers develop scarring, become inflamed, and eventually fail.

2 Sep 2026

New Mechanism Explains How Red Blood Cell Breakdown Drives Inflammation

When red blood cells break down, they release heme, a component of hemoglobin, that can contribute to inflammation and damage tissues and blood vessels.

2 Sep 2026

Bacterial Protein Fragment Disrupts Cell Quality Systems Causing Tissue Scarring

A bacterial protein fragment called corisin drives the process of pulmonary fibrosis by infiltrating and disrupting the cell's quality-control system, researchers at the University of Illinois Urbana-Champaign and Mie University in Japan found in a new study.

1 Sep 2026

Novel Chemical Probes Improve Capture of Elusive DNA Repair Proteins

PARylation is a reversible post-translational modification in which PARP enzymes use NAD+ to assemble PAR chains on proteins. These chains can function as signaling scaffolds that recruit proteins involved in DNA repair, chromatin organization, transcription, and stress responses.

1 Sep 2026

Moving Beyond DNA Sequencing Unlocks New Paths Managing Human Health

Scientists from Gladstone Institutes, UC San Francisco, and Stanford University, in collaboration with Biohub, have unveiled a massive, high-resolution functional map of human immune cells that promises to transform our understanding of how genetics control health and disease.

31 Aug 2026

Tiny Cell Structures Called Peroxisomes Protect Vital Human Insulin Supply

Researchers at LSU's Pennington Biomedical Research Center have identified a previously underappreciated role for tiny structures inside cells called peroxisomes in protecting insulin and maintaining the health and maturity of insulin-producing pancreatic beta cells.

31 Aug 2026

Research Identifies Essential Energy Sources for Developing Carnivorous Larval Fish

Lipids are essential for fish because they supply energy, support cell structure, and help carry fat-soluble nutrients. This is especially important in carnivorous fish, which use carbohydrates less efficiently than many other animals.

25 Aug 2026

Researchers Map First Chromosome-Scale Genomes for Sustainable Prairie Crops

The Land Institute and HudsonAlpha Institute for Biotechnology, in collaboration with key partners, have assembled the first chromosome-scale, haplotype-phased genomes for Silphium integrifolium (rosinweed, silflower) and Silphium perfoliatum (cup plant, silphie).

25 Aug 2026

New Research Links Body Focused Repetitive Behaviors to Hidden Genetics

Two disorders with big names-trichotillomania (repeated hair-pulling) and excoriation disorder (repeated skin-picking)-were the focus of a recent Yale study looking at potential genetic causes.

25 Aug 2026

Scientists Develop Rapid DNA-Based Technique for Estimating Shark Lifespans

This study introduces a DNA-based method for estimating shark ages, crucial for conservation and understanding the life cycles of marine organisms.

24 Aug 2026

New Computational Tool Estimates Cell Age by Analyzing Gene Activity Patterns

Scientists at Karolinska Institutet and Stockholm University have created an innovative tool that determines cellular biological age through gene activity analysis.

24 Aug 2026

Study Redefines How Cancer Cells Enter Senescence

Stopping tumor growth is only half the battle. Rather than kill tumor cells, many cancer therapies can only push them into cellular senescence, a state in which cells stop dividing but do not die. These "undead" cells will continue to release signals that reshape the tumor environment.

21 Aug 2026