Stress News and Research

RSS

SMART Researchers Discover First PLP-Dependent Enzyme That Influences Bacterial Protein Production

Researchers from the Singapore-MIT Alliance for Research & Technology’s (SMART) Antimicrobial Resistance (AMR) interdisciplinary research group, alongside collaborators from Massachusetts Institute of Technology (MIT), Nanyang Technological University (NTU Singapore), and institutions in the United States, Poland, and France, have discovered aminovaleramididine synthetase (AvaS), the first identified pyridoxal phosphate (PLP)-dependent enzyme responsible for producing a chemical modification linked to how bacteria respond to metabolic stress.

10 Sep 2026

IU Biologists Find a Hidden Weak Spot in How Bacteria Build the Tails They Use to Move

New research from Indiana University has uncovered a previously unknown vulnerability in how bacteria build the whip-like tails they use to move.

10 Sep 2026

Multi-Omic Integration Reveals Novel Gene-Disease Links in Undiagnosed Rare Conditions

Researchers from Queen Mary University of London, the Berlin Institute of Health at Charité (BIH) and Genomics England have shown that measuring proteins in the blood can provide important additional clues about the effects of genetic variants, helping to identify diagnoses and potential new disease-causing genes that genome sequencing alone has been unable to resolve.

10 Sep 2026

Computational Chemistry Breakthrough Yields Targeted Molecule for Acute Myeloid Leukemia Treatment

Pushing the accelerator and the brake at the same time is rarely a good idea. But researchers at the University of Gothenburg are using this approach to treat leukemia.

9 Sep 2026

How Can Stressed Mitochondria Actually Protect Your Heart?

Mitochondria are popularly known as the “powerhouse of the cell,” but these cellular structures do so much more–including acting as signaling hubs.

9 Sep 2026

UCLA Breakthrough Generates Thousands of Allogeneic T-Cell Doses From Single Cord Blood Sample

T cell receptor, or TCR, therapy is a cancer treatment that genetically reprograms immune cells, called T cells, to hunt down cancer with precision.

9 Sep 2026

Homolog Gene Regulation Alters Cell-Cycle Progression for Sprouting Trichomes

Trichomes-tiny hair‑like structures on leaves-serve as physical barriers that protect plants from insect herbivores, UV radiation, excessive water loss, and toxic chemicals.

8 Sep 2026

First Chromosome-Level Genome Unveils Blueprints of Valued Medicinal Compounds

Spuriopimpinella brachycarpa, known locally as Dayeqin or Shanqincai, has long been used in traditional medicine to treat colds, indigestion, abdominal pain, and cough.

8 Sep 2026

Salk Study Uncovers How Mitochondrial Signals Drive Lasting Cardioprotection

Mitochondria are popularly known as the "powerhouse of the cell," but these cellular structures do so much more-including acting as signaling hubs.

7 Sep 2026

Research Maps Complex Molecular Rules Governing Specialized Tumor Immunity

For decades, natural killer (NK) cells have been classified into two main groups based on surface markers: one specialized for cytokine production and the other for direct killing.

7 Sep 2026

Genetic Prediction Tools May Misjudge Mutation Risks, Study Finds

When a patient has their DNA read, it gets compared against a reference version of the human genome. It allows geneticists and rare disease experts to look at a list of places where the patient's DNA differs.

4 Sep 2026

Scientists Uncover Unexpected Feature of Human DNA Organization

A new study led by Francesca Storici, a professor in the School of Biological Sciences and faculty member of the Parker H. Petit Institute for Bioengineering and Bioscience, has uncovered an unexpected feature of human DNA linked to gene activity and the physical organization of DNA.

3 Sep 2026

UNC Researcher Wins Mathers Foundation Grant to Study T-Cell Metabolism

Jessica Thaxton, PhD, MsCR, associate professor in the Department of Cell Biology and Physiology at the UNC School of Medicine and co-leader of the Cancer Cell Biology Research Program at UNC Lineberger Comprehensive Cancer Center, has been awarded a prestigious $700,000 grant from the Mathers Foundation to support research into the role of the endoplasmic reticulum in T-cell metabolism and cancer development.

2 Sep 2026

Protein Interaction Helps Senescent Cells Survive Aging and Cellular Stress

Senescent cells - cells that have stopped dividing but remain metabolically active - can accumulate with age and contribute to chronic inflammation and tissue dysfunction

2 Sep 2026

Targeting EFHD1 Protein Prevents Severe Obesity-Related Metabolic Liver Damage

Obesity-related metabolic liver disease affects hundreds of millions of people worldwide, but only some fraction of those livers develop scarring, become inflamed, and eventually fail.

2 Sep 2026

New Mechanism Explains How Red Blood Cell Breakdown Drives Inflammation

When red blood cells break down, they release heme, a component of hemoglobin, that can contribute to inflammation and damage tissues and blood vessels.

2 Sep 2026

Bacterial Protein Fragment Disrupts Cell Quality Systems Causing Tissue Scarring

A bacterial protein fragment called corisin drives the process of pulmonary fibrosis by infiltrating and disrupting the cell's quality-control system, researchers at the University of Illinois Urbana-Champaign and Mie University in Japan found in a new study.

1 Sep 2026

Novel Chemical Probes Improve Capture of Elusive DNA Repair Proteins

PARylation is a reversible post-translational modification in which PARP enzymes use NAD+ to assemble PAR chains on proteins. These chains can function as signaling scaffolds that recruit proteins involved in DNA repair, chromatin organization, transcription, and stress responses.

1 Sep 2026

Moving Beyond DNA Sequencing Unlocks New Paths Managing Human Health

Scientists from Gladstone Institutes, UC San Francisco, and Stanford University, in collaboration with Biohub, have unveiled a massive, high-resolution functional map of human immune cells that promises to transform our understanding of how genetics control health and disease.

31 Aug 2026

Tiny Cell Structures Called Peroxisomes Protect Vital Human Insulin Supply

Researchers at LSU's Pennington Biomedical Research Center have identified a previously underappreciated role for tiny structures inside cells called peroxisomes in protecting insulin and maintaining the health and maturity of insulin-producing pancreatic beta cells.

31 Aug 2026