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Machine Learning Models Identify Early Metabolic Shifts

Acute systemic inflammation has long been suspected to trigger harmful processes within the brain, contributing to neurodegenerative disorders such as Alzheimer's and Parkinson's disease. A new study published online in the Journal of Proteome Research on November 30, 2025, led by Professor Kei Zaitsu from the Faculty of Biology-Oriented Science and Technology, Kindai University, Japan, now provides compelling evidence that such inflammation causes region-specific metabolic disruption, identifying biochemical pathways that fail during the early stages of neuroinflammation.

22 Dec 2025

New Method Enables Direct Freezing of iPS Cells in Culture Dishes

With a Kobe University-developed procedure, induced pluripotent stem cells can now be frozen directly in their dishes without losing their viability or undifferentiated state after thawing.

19 Dec 2025

Smart Hydrogel Senses Infected Wounds and Delivers the Right Treatment

The novel hydrogel adapts to wound environments, offering precise antibacterial and regenerative support, addressing the challenges of infected wounds.

18 Dec 2025

Unlocking the Salutogenic Potential of Microbes

Viruses and bacteria get a bad rap around the world but now Flinders University experts are identifying the positive 'upside' of powerful benefits that microbes have on human health.

18 Dec 2025

A Molecular Tug-of-War Shapes Gene Regulation and Disease

A newly revealed molecular tug-of-war may have implications for better understanding how a multitude of diseases and disorders - including cancers, neurodegenerative diseases and immune disorders - originate, as well as how to potentially treat them, according to researchers at Penn State.

18 Dec 2025

Binocular Multispectral Stereo Imaging Enables High-Resolution Plant Phenotyping

The system enables pixel-level alignment between shape and spectral data, allowing detailed visualization of traits like chlorophyll distribution across plant surfaces.

17 Dec 2025

Theobromine in Dark Chocolate may Slow Biological Aging

A chemical found in dark chocolate could slow the rate of biological aging.

11 Dec 2025

Mitochondrial Supercomplex Protein COX7RP Extends Lifespan and Healthspan

As life expectancy continues to climb globally, the focus of many people has moved from longevity alone to living in good health.

11 Dec 2025

OIST Study Illuminates Cancer's Avoidance of Cellular Stress Responses

When cell division (mitosis) takes too long, it can be a sign that something is wrong with the cells, for example DNA damage or chromosomal instability.

11 Dec 2025

Scientists Discover First Human DNA-Cutting Enzyme That Responds to Tension

An international research team at the University of Hong Kong has discovered a human protein known as ANKLE1, which is recognized as the first DNA-cutting enzyme (nuclease) in mammals that can detect and respond to physical tension in DNA.

10 Dec 2025

Researchers Capture the Most Detailed Images of Molecules in Chromatin Condensates

A team of researchers led by HHMI Investigator Michael Rosen has captured the most detailed images yet of the molecules in chromatin condensates — droplet-like structures of compacted DNA.

5 Dec 2025

Nearly 1/3 of Pesticides and Industrial Chemicals Harm Gut Bacteria

A study reveals that common pesticides and industrial chemicals inhibit gut bacteria, highlighting risks to health and the need for revised safety assessments.

5 Dec 2025

Cells Use Condensates to Save RNA Messages During Stress

All cells need to sense and respond to their environment, to know when to activate genes, build proteins, and carry out their basic functions.

4 Dec 2025

Harnessing Triploid Loquat to Unlock Aneuploid Diversity for Advanced Breeding

Triploid plants are widely valued in horticulture for desirable traits such as seedlessness, yield improvement, and stress resilience.

2 Dec 2025

Study Uncovers How Polyploid Plants Harness Transposons for Evolutionary Innovation

Polyploidization, the combination and duplication of genomes, is a major driver of plant evolution and diversification. Yet this process causes "genome shock," leading to rapid activation of transposable elements (TEs).

2 Dec 2025

Mitochondrial Mutation Found to Rewire Immune Function

Scientists have discovered how a mitochondrial mutation rewires immune function in a model of inherited primary mitochondrial disorders, which often lead to severe disability and death.

27 Nov 2025

Scientists Uncover Inner Workings of Biomolecular Condensates Linked to ALS

Inside the cell reside many tiny assembly factories and warehouses that gather together all of the proteins and RNAs-which carry out instructions from our DNA-that a living being needs.

27 Nov 2025

Nobel Prize-Awarded Material That Puncture and Kill Bacteria

Bacteria that multiply on surfaces are a major headache in healthcare when they gain a foothold on, for example, implants or in catheters.

27 Nov 2025

Ribosome Collisions Activate Key Stress Signaling Mechanisms in Cells

LMU researchers uncover the mechanism by which ribosomes raise alarms in the cell.

25 Nov 2025

Optogenetic Tool Uncovers Key Role of Mechanical Forces in Early Embryonic Development

Only two weeks after fertilization, the first sign of the formation of the 3 axes of the human body (head/tail, ventral/dorsal, and right/left) begins to appear.

24 Nov 2025