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Blood protein test helps spot hidden cancers in patients with vague symptoms

Plasma protein profiling offers a promising tool for cancer risk stratification in patients with non-specific symptoms, potentially reducing diagnostic delays.

28 Jan 2026

Gut Bacteria Use Protein Injection to Influence Human Immune System

Bacteria in the human gut can directly deliver proteins into human cells, actively shaping immune responses.

27 Jan 2026

Age-Related Changes in the Gut Microbiota Impair Intestinal Stem Cells

A new study led by Hartmut Geiger at the University of Ulm, Germany, and Yi Zheng and Kodandaramireddy Nalapareddy, Cincinnati Children's Hospital Medical Center (CCHMC), USA reveals that age-related changes in the gut microbiota directly impair intestinal stem cell (ISC) function and that restoring a youthful microbial environment can reverse this decline.

24 Jan 2026

Trojan Horse Drug Works in Combination With Copper to Kill Bacteria

A research team at the University of Arizona College of Medicine – Tucson is developing a drug that works in combination with copper to kill bacteria, including those that cause MRSA, a type of staph infection that is resistant to usual treatments.

24 Jan 2026

Protein Translation Enzyme Governs Macrophage Maturation and Tissue Homeostasis

A new study led by researchers at the Johns Hopkins Kimmel Cancer Center, its Bloomberg~Kimmel Institute for Cancer Immunotherapy and the Johns Hopkins Bloomberg School of Public Health found that an enzyme involved in protein translation is essential for circulating immune cells, called monocytes, to mature into tissue-resident macrophages, a specialized population of immune cells that maintain organ health by clearing dead cells and debris.

24 Jan 2026

DHPS Enzyme Deficiency Impairs Macrophage Development and Tissue Repair

22 Jan 2026

A Week of 40-Hz Sound Triggers Long-Lasting Amyloid Changes in Monkeys

Forty-hertz auditory stimulation in aged monkeys doubles CSF amyloid-β levels, offering insights into non-invasive strategies for Alzheimer's disease treatment.

15 Jan 2026

Giant Virus Uses Unique Codon Strategy to Optimize Host Resource Usage

A virus relies on the host's translation machinery to replicate itself and become infectious. Translation efficiency partially depends on the usage of a codon, or sequence of three nucleotides, that matches the cellular pool of tRNA, key molecules in translation.

12 Jan 2026

Population-Specific Proteomic Analysis Advances Precision Medicine for Type 2 Diabetes

Researchers have conducted the most comprehensive analysis to date linking plasma proteins to genetic variation in individuals from continental Africa.

9 Jan 2026

Deep Learning–Based Codon Optimization Framework Boosts Protein Expression in E. coli

By combining Transformer-based sequence modeling with a novel conditional probability strategy, the approach overcomes long-standing trade-offs between maximizing expression metrics and maintaining translational features critical for proper protein folding.

9 Jan 2026

Synthetic Biology and Metabolic Engineering Drive Microbial L-Tryptophan Biomanufacturing

This review synthesizes progress in pathway optimization, regulatory rewiring, and microbial cell factory design that has driven L-Trp titers to industrially relevant levels while enabling the biosynthesis of downstream products ranging from neurotransmitters and plant hormones to dyes and complex alkaloids.

8 Jan 2026

USU Researchers Discover CRISPR Cas12a3's Potential for Viral Protein Inhibition

Across all domains of life, immune defenses foil invading viruses by making it impossible for the viruses to replicate. Most known CRISPR systems target invading pathogens' DNA and chop it up to disable and modify genes, heading off infections at the (cellular) pass.

8 Jan 2026

Turning Human Fat into Insulin-Producing Organoids That Reverse Diabetes

By preserving fat tissue architecture, researchers created organoids that restore insulin function, paving the way for advancements in diabetes treatment.

8 Jan 2026

Microneedle Patches May Unlock Safer, Localized Cancer Immunotherapy

This review highlights the potential of natural polysaccharide microneedles in cancer immunotherapy, focusing on localized treatment and immune activation.

7 Jan 2026

Blocking Retinoic Acid Pathway Improves Dendritic Cell Anti-Tumor Function

Scientists at the Princeton University Branch of the Ludwig Institute for Cancer Research have identified novel mechanisms by which a metabolic derivative of vitamin A-all-trans retinoic acid-compromises both the body's normal anti-cancer immune response and, in a different context, the efficacy of a promising type of cancer vaccine.

6 Jan 2026

Wasatch Biolabs Announces Co-Marketing Agreement with Agilent to Advance Native-Read Targeted Sequencing

Wasatch BioLabs (WBL), a leader in native, long-read sequencing and epigenomic analysis, today announced a co-marketing agreement with Agilent Technologies to support the adoption of its Direct Targeted Methylation Sequencing (dTMS) platform.

22 Dec 2025

A Global Catalog of Human Pluripotent Stem Cell Lines for Clinical Use

To date, more than 100 clinical trials with human pluripotent stem cell (hPSC)-derived products have been initiated worldwide and an increasing number of potential hPSC-derived clinical products have entered early developmental pipelines.

19 Dec 2025

Cells Use Condensates to Save RNA Messages During Stress

All cells need to sense and respond to their environment, to know when to activate genes, build proteins, and carry out their basic functions.

4 Dec 2025

Circular Single-Stranded DNA Molecule Can Simultaneously Silence Multiple MicroRNAs

Professor Dongsheng Liu of Tsinghua University, Professor Ziyang Hao of Capital Medical University, and Researcher Yuanchen Dong of the Institute of Chemistry, Chinese Academy of Sciences, have collaborated to develop a circular single-stranded DNA molecule capable of simultaneously silencing multiple miRNAs.

4 Dec 2025

New Comprehensive Atlas Transforms Understanding of Neutrophil Diversity

Neutrophils are the most abundant immune cells in the body and the first to respond to infection or tissue damage.

4 Dec 2025

Translation News and Research

Blood protein test helps spot hidden cancers in patients with vague symptoms

Gut Bacteria Use Protein Injection to Influence Human Immune System

Age-Related Changes in the Gut Microbiota Impair Intestinal Stem Cells

Trojan Horse Drug Works in Combination With Copper to Kill Bacteria

Protein Translation Enzyme Governs Macrophage Maturation and Tissue Homeostasis

DHPS Enzyme Deficiency Impairs Macrophage Development and Tissue Repair

A Week of 40-Hz Sound Triggers Long-Lasting Amyloid Changes in Monkeys

Giant Virus Uses Unique Codon Strategy to Optimize Host Resource Usage

Population-Specific Proteomic Analysis Advances Precision Medicine for Type 2 Diabetes

Deep Learning–Based Codon Optimization Framework Boosts Protein Expression in E. coli

Synthetic Biology and Metabolic Engineering Drive Microbial L-Tryptophan Biomanufacturing

USU Researchers Discover CRISPR Cas12a3's Potential for Viral Protein Inhibition

Turning Human Fat into Insulin-Producing Organoids That Reverse Diabetes

Microneedle Patches May Unlock Safer, Localized Cancer Immunotherapy

Blocking Retinoic Acid Pathway Improves Dendritic Cell Anti-Tumor Function

Wasatch Biolabs Announces Co-Marketing Agreement with Agilent to Advance Native-Read Targeted Sequencing

A Global Catalog of Human Pluripotent Stem Cell Lines for Clinical Use

Cells Use Condensates to Save RNA Messages During Stress

Circular Single-Stranded DNA Molecule Can Simultaneously Silence Multiple MicroRNAs

New Comprehensive Atlas Transforms Understanding of Neutrophil Diversity

How Avatar Medical's 3D Technology Is Transforming How We Visualize the Human Body

Driving Support for Pharmaceutical Testing Through Continuous Innovation

From Memory to Metaplasticity: Unraveling the Brain's Secrets

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