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Marine Carbohydrate Therapeutics: From Structural Diversity to Clinical Translation

The ocean contains diverse carbohydrates that could serve as valuable resources for drug development. Algae, marine animals and microorganisms produce polysaccharides and related molecules with structures that are uncommon on land, including distinctive sulfate patterns, sugar linkages and branched architectures.

24 Sep 2026

Novel Organoid Platform Reveals Non-Immune Drivers of Diabetic Renal Injury

Stem cell researchers have identified inflammatory pathways that may play a key role in driving kidney damage in diabetic kidney disease (DKD), pointing to potential new approaches for protecting the kidneys.

18 Sep 2026

Research Maps Complex Molecular Rules Governing Specialized Tumor Immunity

For decades, natural killer (NK) cells have been classified into two main groups based on surface markers: one specialized for cytokine production and the other for direct killing.

7 Sep 2026

AI-Designed Protein Vehicle Enables Lower RNA Dosing While Maximizing Therapeutic Protein Expression

Researchers at Helmholtz Munich and TUM have developed Synthetic Transfer Vehicles (STVs), an entirely new class of RNA transporters. To do so, they combined naturally occurring protein building blocks with synthetic protein structures designed using generative AI.

3 Sep 2026

Optical Metabolic Imaging Profiles Single-Cell Metabolic Fitness in Blood Without Dye Labeling

A routine blood sample contains a diverse collection of immune cells that can reveal important clues about health and disease. These cells, known as peripheral blood mononuclear cells (PBMCs), are widely used to study infections, autoimmune disorders, cancer, and the immune system's response to treatment.

3 Sep 2026

Novel Chemical Probes Improve Capture of Elusive DNA Repair Proteins

PARylation is a reversible post-translational modification in which PARP enzymes use NAD+ to assemble PAR chains on proteins. These chains can function as signaling scaffolds that recruit proteins involved in DNA repair, chromatin organization, transcription, and stress responses.

1 Sep 2026

Genetically Engineered Marine Bacteria Accelerate Global Carbon Dioxide Removal Efforts

Rock weathering, the breakdown and dissolving of rocks and minerals caused by their exposure to water, air, and biological life, is a major regulator of Earth's atmospheric CO2 levels and climate.

31 Aug 2026

Experimental Platform Could Rapidly Deliver Next-Generation mRNA Therapeutics

In a new study, scientists from Johns Hopkins Medicine report that an experimental mRNA-based platform has the potential to help deliver next-generation mRNA therapeutics, including vaccines fighting against infectious disease, cancer and autoimmune conditions, faster and more efficiently than the industry standard.

21 Aug 2026

Reengineering Glial Cell Signaling Pathways to Slow Down ALS Symptoms

Amyotrophic lateral sclerosis (ALS) is a neurodegenerative disease that, according to the CDC, currently impacts around 35,000 Americans-with 5,000 more diagnosed each year.

21 Aug 2026

Study Shows How Compact Viral Structures Boost Protein Yields for mRNA Vaccines

A research team led by Director KIM V. Narry at the Center for RNA Research within the Institute for Basic Science (IBS) has discovered compact viral RNA elements that can make mRNA more stable and increase protein production.

17 Aug 2026

Cells Deploy Specialized Quality Control Factors When Protein Synthesis Fails

Scientists at the Center for Molecular Medicine Cologne (CMMC) and the CECAD Cluster of Excellence on Aging Research have demonstrated in a biomedical study that ribosomes, the protein factories of our cells, face an unusually tough challenge when building large, membrane‑embedded proteins.

13 Aug 2026

Neural Stem Cell Protein CCN1 Guides Microglial Distribution During Development

The development of the central nervous system (CNS) depends on the coordinated interactions between neural stem cells (NSCs) and resident immune cells to regulate neurogenesis, tissue organization, and brain maturation.

12 Aug 2026

Emerging m6A RNA Biology Explains Brain Vulnerability to Environmental Hazards

A growing understanding of RNA biology is reshaping how scientists view the relationship between environmental toxicants, brain development, and neurodegenerative disease.

7 Aug 2026

New Framework Uses Genetic Variant Data to Recall Biobank Participants

Clinical biobanks that combine genomic data with electronic health records (EHRs) have become powerful resources for discovering genetic variants associated with disease.

28 Jul 2026

Research Decodes How Gut Microbes Process Plant-Based Nutrients

Plant-based diets are good for you. They promote gut, immune, metabolic and cardiovascular health, in part by cultivating a diverse community of intestinal bacteria.

28 Jul 2026

Novel Dendritic Cell Vaccine Redirects Viral Memory to Fight Tumors

In a discovery that could redefine the future of cancer immunotherapy, scientists from Celloram Inc., University Hospitals and Case Western Reserve University have developed a novel cancer vaccine platform that transforms the impact of the largest immunological event in modern history

28 Jul 2026

AI-Assisted Paper Test Measures Three Cardiac Biomarkers in 23 Minutes

Researchers developed an AI-assisted dual-mode paper assay that measures cTnI, CK-MB, and NT-proBNP from 50 µL of serum in 23 minutes. In single-site analytical validation, neural networks quantified the three biomarkers across distinct concentration ranges, supporting further development for multiplexed cardiac testing at the point of care.

27 Jul 2026

Study Reveals How Genome Regulation Changes During Brain Aging

Researchers have discovered that the human brain undergoes widespread age-related changes in genome regulation beginning in midlife that may help explain why aging is the greatest risk factor for neurodegenerative diseases such as Alzheimer's.

24 Jul 2026

UC San Diego and Innovative Genomics Institute Partner to Develop Cutting-Edge Genomic Tools

The University of California San Diego and the Innovative Genomics Institute (IGI), founded by Nobel laureate and CRISPR gene editing co-discoverer Jennifer Doudna, announced a new partnership today to jointly develop cutting-edge genomic tools for addressing large-scale challenges in health and the environment.

21 Jul 2026

Female Hearts Rely on Molecular Safeguard to Avoid Failure

Men and women are not born with the same risk of heart disease, and for decades scientists have struggled to explain why. A new study from the University of North Carolina at Chapel Hill, published in Genes & Development, offers a striking answer: the female heart depends on a molecular safeguard that the male heart can largely do without - and when that safeguard is removed, female hearts fail while male hearts keep beating.

20 Jul 2026