therapeutics News and Research

RSS

Systematic Genetic Mapping Opens New Doors for Tuberculosis Drug Discovery

Rockefeller scientists have created the most comprehensive map to date of how essential genes interact in Mycobacterium tuberculosis (Mtb), the bacterium responsible for tuberculosis (TB).

5 Nov 2026

Novel Molecular Bridge Links Coagulation Cascade with Cancer Hormonal Environment

New Cleveland Clinic research published in Cancer Cell shows that people with glioblastoma have more active platelets, which are cells involved in blood clotting. Platelets also communicate with other cells and can influence immune activity.

4 Nov 2026

Unraveling the Molecular Complexity of SARS-CoV-2 Genome Regulation

A study led by researchers at the University of California San Diego School of Medicine and University of California, Riverside (UCR) School of Medicine has identified new targets for antiviral drugs against coronaviruses, including SARS-CoV-2, the virus that causes COVID-19.

4 Nov 2026

Switching on Healthy Silent Genes Reveals New Way to Treat Rare Genetic Disorder

WEHI researchers have discovered a way to release a genetic 'brake' that silences healthy genes in Prader-Willi syndrome, opening a potential new path to treating the condition.

27 Oct 2026

PARP1 Disassembles Nucleosomes to Facilitate Essential DNA Damage Repair

When DNA is damaged, cellular processes respond and repair the DNA. Inhibiting DNA damage repair can be therapeutically beneficial in cancers with genetic vulnerabilities related to DNA damage response.

26 Oct 2026

New Genetic Map Identifies Variations Linked to Long QT Syndrome

Using an innovative, high-throughput technique, an international collaboration led by Vanderbilt Health researchers has created a "map" of 1,757 genetic variations that can trigger a life-threatening heart rhythm disorder called long QT syndrome.

24 Oct 2026

Carrier-Free Jet Vaccine Method Protects Against COVID-19 and Flu in Animal Studies

A needle-free vaccination method protected mice against the viruses that cause COVID-19 and flu, offering a possible new way to deliver mRNA vaccines while limiting unwanted inflammation.

24 Oct 2026

BioUK Awards 2026 Celebrate Outstanding Achievement and Breakthrough Innovations from Across the Life Sciences

BioUK, the not-for-profit membership organization focused on catalyzing success in UK life sciences, today announced the winners of the 18th annual BioUK Awards following a ceremony hosted at the Royal Lancaster Hotel, London.

From BioUK 23 Oct 2026

Accelerating RNA Therapeutics Research with High Throughput Screening

Oligonucleotides have the potential to transform the treatment of a wide range of diseases, and have extensive applications in biomedical research.

From INTEGRA Biosciences 22 Oct 2026

Eppendorf and BioLabs Expand Collaboration to Support Biotech Innovation in Munich

Eppendorf, a leading international life science company that develops, manufactures, and distributes instruments, consumables, and services for use in laboratories around the world, and BioLabs, a global innovation infrastructure company creating the physical and community backbone that powers life science discovery worldwide, today announced the expansion of their collaboration to BioLabs’ new Munich site, BioLabs | TUM, extending a relationship that already includes BioLabs locations in the U.S, France and Germany.

From Eppendorf SE 22 Oct 2026

Stable Isotope Carbon Tracing Proves Uncoupling Inhibits De Novo Purine Synthesis

Mitochondrial serine catabolic pathway (MSCP), also called serine, glycine, and one-carbon metabolism, is essential for cancer cells to produce amino acids, one-carbon units, and reducing equivalents.

20 Oct 2026

Study: Maternal Autoantibodies Targeting IL-1RA Trigger Premature Labor

A typical pregnancy lasts 40 weeks, but for about 1 in 10 pregnant women labor begins too soon. Premature or preterm birth is the leading cause of newborn deaths worldwide. Yet doctors have struggled to understand why preterm birth occurs - or how to predict which pregnancies are at highest risk.

15 Oct 2026

Transcriptional Repression Mechanism Prevents Protective Immune Pathways From Triggering Autoimmunity

A preclinical study by researchers at UT Southwestern Medical Center has discovered how a protein called ZBTB44 helps prevent excessive immune activity that can cause inflammation in the colon, the main section of the large intestine. The findings, published in Nature Immunology, may help explain how immune responses go awry in a range of chronic inflammatory and autoimmune diseases

13 Oct 2026

Researchers Capture Real-Time Molecular Movie of Penicillin Enzymatic Ring Closure

Researchers from the University of Oxford and international collaborators have revealed previously unseen rapid chemical stages in the formation of β-lactam antibiotics like penicillin, offering insights that can support future antibiotic development.

10 Oct 2026

Research Consortium Maps Mitochondrial Diversity Across the Complex Tree of Life

A research consortium has generated the broadest look yet at the proteins that make up mitochondria, capturing the organelle's diversity across multiple branches on the tree of complex life.

5 Oct 2026

Novel Two-Dimensional Mapping Combines Generation Probability with Somatic Hypermutation

A research team led by Associate Professor Yohei Funakoshi, Associate Professor Kimikazu Yakushijin, and Professor Hironobu Minami of the Division of Medical Oncology/Hematology at Kobe University Hospital, together with Associate Professor Goh Ohji of the Division of Infectious Disease Therapeutics and Takaji Matsutani of Anymics Inc., has developed the pGen-SHM plot.

5 Oct 2026

Dr. GPCR and Eurofins Discovery Join Forces to Advance GPCR Drug Discovery

Dr. GPCR, the global knowledge hub for G protein-coupled receptor (GPCR) research and education, today announced a strategic partnership with Eurofins Discovery, the drug discovery services side of the same group behind the Eurofins DiscoverX products many in the community already know.

From Dr. GPCR 5 Oct 2026

Single-Cell Sequencing Confirms Epigenetic Remodeling Across Diverse Cardiac Cell Types

The adult human heart is a reliable and resilient engine fueling our everyday lives while also being responsive enough to supercharge a Usain Bolt sprint or sustain a three-week bike race in the French Alps and Pyrenees.

29 Sep 2026

Post-Translational Modification Crosstalk Regulates Oncogenic Protein Stability and Activity

A review published in Genes & Diseases highlights the complex interplay between protein arginine methylation and ubiquitination, two forms of protein modification that can profoundly influence cancer development, progression and treatment response. The article brings together current understanding of how these interconnected molecular processes regulate proteins involved in cancer and identifies opportunities for future therapeutic approaches.

28 Sep 2026

Engineered 3D miBrains Model Human Neurovascular Units and Pathology

Mount Sinai researchers have identified how APOE4, the strongest genetic risk factor for Alzheimer's disease, damages the brain's blood vessels and promotes the buildup of abnormal proteins linked to neurodegenerative disease.

26 Sep 2026