therapeutics News and Research

RSS

Research Consortium Maps Mitochondrial Diversity Across the Complex Tree of Life

A research consortium has generated the broadest look yet at the proteins that make up mitochondria, capturing the organelle's diversity across multiple branches on the tree of complex life.

5 Oct 2026

Novel Two-Dimensional Mapping Combines Generation Probability with Somatic Hypermutation

A research team led by Associate Professor Yohei Funakoshi, Associate Professor Kimikazu Yakushijin, and Professor Hironobu Minami of the Division of Medical Oncology/Hematology at Kobe University Hospital, together with Associate Professor Goh Ohji of the Division of Infectious Disease Therapeutics and Takaji Matsutani of Anymics Inc., has developed the pGen-SHM plot.

5 Oct 2026

Dr. GPCR and Eurofins Discovery Join Forces to Advance GPCR Drug Discovery

Dr. GPCR, the global knowledge hub for G protein-coupled receptor (GPCR) research and education, today announced a strategic partnership with Eurofins Discovery, the drug discovery services side of the same group behind the Eurofins DiscoverX products many in the community already know.

From Dr. GPCR 5 Oct 2026

Single-Cell Sequencing Confirms Epigenetic Remodeling Across Diverse Cardiac Cell Types

The adult human heart is a reliable and resilient engine fueling our everyday lives while also being responsive enough to supercharge a Usain Bolt sprint or sustain a three-week bike race in the French Alps and Pyrenees.

29 Sep 2026

Post-Translational Modification Crosstalk Regulates Oncogenic Protein Stability and Activity

A review published in Genes & Diseases highlights the complex interplay between protein arginine methylation and ubiquitination, two forms of protein modification that can profoundly influence cancer development, progression and treatment response. The article brings together current understanding of how these interconnected molecular processes regulate proteins involved in cancer and identifies opportunities for future therapeutic approaches.

28 Sep 2026

Engineered 3D miBrains Model Human Neurovascular Units and Pathology

Mount Sinai researchers have identified how APOE4, the strongest genetic risk factor for Alzheimer's disease, damages the brain's blood vessels and promotes the buildup of abnormal proteins linked to neurodegenerative disease.

26 Sep 2026

3D Stem-Cell miBrains Model Complex Neurovascular Pathology in Human Tissue

25 Sep 2026

Marine Carbohydrate Therapeutics: From Structural Diversity to Clinical Translation

The ocean contains diverse carbohydrates that could serve as valuable resources for drug development. Algae, marine animals and microorganisms produce polysaccharides and related molecules with structures that are uncommon on land, including distinctive sulfate patterns, sugar linkages and branched architectures.

24 Sep 2026

Study Uncovers Two-Protein Repair Mechanism Preserving Circular ecDNA Stability

Researchers at Memorial Sloan Kettering Cancer Center (MSK) and their colleagues have discovered that a type of rogue DNA found in aggressive cancers has a hidden structural weakness - and that blocking a single repair protein can cause it to fall apart, suggesting a new therapeutic opportunity.

24 Sep 2026

Cambridge Researchers Look Inside Living Antarctic Cells for First Time

Engineers have built the first microscope to see inside living cells in sub-zero conditions, revealing secrets of Antarctic fish survival.

23 Sep 2026

Researchers Identify Peptide That Counters Key Processes of Neurodegenerative Disorders

Alzheimer's disease and related neurodegenerative disorders are among medicine's most challenging conditions, progressively impairing memory, movement and independence. Now, researchers at the University of California San Diego School of Medicine have identified a naturally occurring peptide - a small protein fragment called catestatin (CST) - that may help counter several key processes driving neurodegeneration.

23 Sep 2026

Uncovering B Cell Signaling Pathways to Enhance Targeted T Cell Immunotherapies

Cancer is the second leading cause of death in the United States, according to a 2026 Cancer Research Institute report. Cancer biologists are keenly aware of this statistic, as it drives them to innovations that revolutionize cancer care-innovations like immunotherapy.

17 Sep 2026

Genetic Redundancy Allows Cells to Optimize mRNA Sequences Against Aggregation

Messenger RNA, or mRNA, is best known for carrying genetic instructions from DNA to the cellular machinery that makes proteins. But all RNA molecules have another, less appreciated property: they are naturally sticky.

17 Sep 2026

Researchers Analyze Somatic DNA Integrity across Complex Longevity Pathways

A new review was published in Volume 18 of Aging on August 26, 2026, titled "Assessing mechanisms and evidence of a causal role for cellular senescence and somatic mutations in aging."

15 Sep 2026

Icosagen Develops Manufacturing-Ready CHO Cell Line for EPOK Therapeutics' Complex Tetravalent Antibody-Like Protein

Icosagen, a private European protein therapeutics CRDMO, and EPOK Therapeutics Inc., a pre-clinical-stage biopharmaceutical company, based in Toronto, Canada, today announced the successful completion of a development project for EPOK's novel antibody EPRA-0322.

From Icosagen 15 Sep 2026

Researchers Locate Cortical Cells That Actively Trigger Brain Sleep

What makes the brain fall asleep? For nearly a century, scientists have looked to structures deep within the brain for the answer.

12 Sep 2026

Reprogramming Tumor Immune Microenvironment to Combat Aggressive Glioblastoma Brain Cancer

Mayo Clinic researchers have identified a potential new approach to treating glioblastoma that could help the immune system fight the aggressive brain cancer while improving the effectiveness of existing chemotherapy.

11 Sep 2026

SMART Researchers Discover First PLP-Dependent Enzyme That Influences Bacterial Protein Production

Researchers from the Singapore-MIT Alliance for Research & Technology’s (SMART) Antimicrobial Resistance (AMR) interdisciplinary research group, alongside collaborators from Massachusetts Institute of Technology (MIT), Nanyang Technological University (NTU Singapore), and institutions in the United States, Poland, and France, have discovered aminovaleramididine synthetase (AvaS), the first identified pyridoxal phosphate (PLP)-dependent enzyme responsible for producing a chemical modification linked to how bacteria respond to metabolic stress.

10 Sep 2026

Synchronized Gene Regulatory Pathways Defend C. diff Against Host and Microbiota Threats

The pathogen Clostridioides difficile (C. diff) - a leading cause of hospital-acquired infections - must contend with a variety of threats inside the harsh environment of the gut to survive and grow.

10 Sep 2026

Advanced Gene Editing Provides Essential Tool for Studying Early Human Embryonic Development

A study by researchers at Columbia University Vagelos College of Physicians and Surgeons has found that new cutting-edge techniques can accurately edit genes in human embryos-giving scientists indispensable tools for understanding normal human development-but has also uncovered important risks that currently preclude the use of the techniques in the clinic.

10 Sep 2026

therapeutics News and Research

Research Consortium Maps Mitochondrial Diversity Across the Complex Tree of Life

Novel Two-Dimensional Mapping Combines Generation Probability with Somatic Hypermutation

Dr. GPCR and Eurofins Discovery Join Forces to Advance GPCR Drug Discovery

Single-Cell Sequencing Confirms Epigenetic Remodeling Across Diverse Cardiac Cell Types

Post-Translational Modification Crosstalk Regulates Oncogenic Protein Stability and Activity

Engineered 3D miBrains Model Human Neurovascular Units and Pathology

3D Stem-Cell miBrains Model Complex Neurovascular Pathology in Human Tissue

Marine Carbohydrate Therapeutics: From Structural Diversity to Clinical Translation

Study Uncovers Two-Protein Repair Mechanism Preserving Circular ecDNA Stability

Cambridge Researchers Look Inside Living Antarctic Cells for First Time

Researchers Identify Peptide That Counters Key Processes of Neurodegenerative Disorders

Uncovering B Cell Signaling Pathways to Enhance Targeted T Cell Immunotherapies

Genetic Redundancy Allows Cells to Optimize mRNA Sequences Against Aggregation

Researchers Analyze Somatic DNA Integrity across Complex Longevity Pathways

Icosagen Develops Manufacturing-Ready CHO Cell Line for EPOK Therapeutics' Complex Tetravalent Antibody-Like Protein

Researchers Locate Cortical Cells That Actively Trigger Brain Sleep

Reprogramming Tumor Immune Microenvironment to Combat Aggressive Glioblastoma Brain Cancer

SMART Researchers Discover First PLP-Dependent Enzyme That Influences Bacterial Protein Production

Synchronized Gene Regulatory Pathways Defend C. diff Against Host and Microbiota Threats

Advanced Gene Editing Provides Essential Tool for Studying Early Human Embryonic Development

The Future of Vision Restoration With ReVision Implant

How a Single List Is Changing Visibility for Women in Science

How Avatar Medical's 3D Technology Is Transforming How We Visualize the Human Body

RecentIndustryFocuses

Editorial Focus eBook - Biopharmaceuticals (2nd edition)

Improving Cell Culture Efficiency with Image-Guided Automation

Improving Scalability in Organoid Research

Cosmetic Formulation and Manufacturing

Latest in Genomics