Acute Respiratory Distress Syndrome News and Research

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Blunted inflammatory response in obese individuals responsible for susceptibility to severe COVID-19

Individuals who are obese may be more susceptible to severe COVID-19 because of a poorer inflammatory immune response, say Cambridge scientists.

23 Mar 2023

Blunted inflammatory response could make obese patients more susceptible to severe COVID-19

Individuals who are obese may be more susceptible to severe COVID-19 because of a poorer inflammatory immune response, say Cambridge scientists.

21 Mar 2023

Understanding the role of ORF8 viral gene in COVID-19 infection and outcomes

A research team led by Jae Jung, PhD, Director of Cleveland Clinic's Global Center for Pathogen & Human Health Research, has uncovered the critical role a viral gene, ORF8, plays in infection and disease outcomes of Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2), the virus that causes COVID-19.

8 Apr 2022

Pyroptosis is not a one-way ticket, it can be halted and controlled

A study published by researchers at the University of Illinois Chicago describes a new method for analyzing pyroptosis -; the process of cell death that is usually caused by infections and results in excess inflammation in the body -; and shows that process, long thought to be irreversible once initiated, can in fact be halted and controlled.

11 Jan 2022

Novel delivery system for genome editing in vascular endothelial cells developed

The laboratory of Youyang Zhao developed a novel nanoparticle to deliver genome editing technology, such as CRISPR/Cas9, to endothelial cells, which line blood vessel walls.

7 Jan 2022

Researchers devise a new method for safer delivery of RNA drugs

Scientists have developed and tested a library of lipid-based compounds for the safe and effective delivery of RNA drugs to the lungs.

3 Aug 2021

Researchers identify new therapeutic target to fight COVID-19 disease

In COVID-19 patients with severe lung disease, targeting the endothelial cells—that is, cells comprising the blood vessel wall, which control oxygen exchange between the bloodstream and airways—may be an innovative strategy to restore normal function of the lungs.

15 Dec 2020

Researchers unravel molecular factors that drive severity of COVID-19

While most COVID-19 cases are asymptomatic or mild, severe complications associated with acute respiratory distress have led to more than one million deaths worldwide in just several months.

14 Oct 2020

Researchers identify specific cellular pathway involved in the regeneration of lung tissue

Scientists have discovered a new cellular pathway that can be targeted with a naturally occurring medication to activate the regeneration of lung tissue.

30 Sep 2020

Druggable pocket in SARS-CoV-2 Spike protein can help eliminate COVID-19

Researchers have identified a druggable pocket in the SARS-CoV-2 Spike protein that could be utilized to prevent the virus from infecting human cells.

24 Sep 2020

Sticky DNA webs may cause tissue damage linked to severe COVID-19

Sticky webs of DNA released from immune cells known as neutrophils may cause much of the tissue damage associated with severe COVID-19 infections, according to two new studies published on September 14 in the Journal of Experimental Medicine (JEM).

15 Sep 2020

Researchers review the role of macrophage activation syndrome in COVID-19

A major percentage of COVID-19 cases have become so severe that hospital admissions have become mandatory for both monitoring and treatment.

10 Sep 2020

Researchers identify an effective treatment for severe cases of COVID-19 infection

Scientists are trying to figure out how SARS-CoV-2 leads to a range of symptoms that appear to persist long after the active viral infection.

From Osaka University 1 Sep 2020

Macrophage programming allows the body to fight infections and promotes tissue repair

Macrophages are white blood cells that, depending on the signals they get from the immune system, become specialized in either increasing or decreasing inflammation.

26 Aug 2020

New methods to regulate enzymes involved in SARS-CoV-2 virus infection

A research team from the HSE University has designed innovative methods for controlling the expression of TMPRSS2 and ACE2 enzymes.

30 Jul 2020

Testing COVID-19 with FDA-approved drugs can improve outcomes for affected patients

A protein found in viruses that are responsible for causing SARS and COVID-19 infections is virtually identical.

29 Jul 2020

Higher levels of specific protein linked with severity of COVID-19 symptoms

A new study found raised levels of transforming growth factor beta-induced protein (TGFBIp) in blood sampled from roughly 100 people hospitalized for COVID-19, and further found that elevated levels of both the normal and acetylated forms of TGFBIp correlated with the severity of disease symptoms in these patients.

27 Jul 2020