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A safer treatment harnesses the body's cancer-fighting T cells to fight multiple myeloma

A treatment for multiple myeloma that harnesses the body's cancer-fighting T cells was safe in humans and showed preliminary signs of effectiveness, according to a clinical trial involving 23 patients with relapsed or treatment-resistant disease.

30 Jul 2020

Clinical trial shows CAR-T cell therapy can be used for treating Hodgkin lymphoma

CAR-T cell therapy, which attacks cancer cells using a person's reprogrammed immune cells, has been used to treat Hodgkin lymphoma with remarkable success for the first time, according to the results of an early phase clinical trial led by researchers at UNC Lineberger Comprehensive Cancer Center and Baylor College of Medicine in Houston.

24 Jul 2020

New approach is more effective in treating certain blood cancers

Some of the most promising advances in cancer treatment have centered on immunotherapies that rev up a patient's immune system to attack cancer.

24 Jul 2020

Fusion protein found to effective at treating pulmonary arterial hypertension

Pulmonary arterial hypertension (PAH) is an insidious disease. Symptoms may begin slowly, and even before they appear, extensive damage has caused the obstruction of small arteries leading to increased blood pressure in the lungs.

22 Jul 2020

UC Davis Health tests new antibody combination as potential treatment for COVID-19

Timothy Albertson, chair of internal medicine and specialist in pulmonary and critical care, is leading efforts at UC Davis Health to test a new antibody cocktail (REGN-COV2) as a prevention and treatment for COVID-19.

From The University of California, Davis 21 Jul 2020

Scientists gain insights into how parasitic bacterium gives rise to lesions

Bacteria of the genus Bartonella are parasites that can be transmitted to humans via insect bites and animal scratches, resulting in an infection known as "bartonellosis." Cat-scratch disease and trench fever are forms of bartonellosis caused by different Bartonella species infecting humans.

17 Jul 2020

New, promising CAR T cell therapy results in exceptional patient recovery

In a clinical trial evaluating a novel immunotherapy option for cancer treatment, a child with rhabdomyosarcoma, a form of muscle cancer, that had spread to the bone marrow, showed no detectable cancer following treatment with chimeric antigen receptor (CAR) T cells that were engineered to target the HER2 protein on the surface of cancerthe cells.

16 Jul 2020

Investigational COVID-19 vaccine is safe, generates neutralizing antibody activity in healthy adults

An investigational vaccine, mRNA-1273, designed to protect against SARS-CoV-2, the virus that causes coronavirus disease 2019 (COVID-19), was generally well tolerated and prompted neutralizing antibody activity in healthy adults, according to interim results published online today in The New England Journal of Medicine.

15 Jul 2020

Keck Medicine of USC participates in clinical trial to test antiviral drug as potential COVID-19 treatment

Keck Medicine of USC physicians are enrolling patients as part of an international clinical trial to evaluate the safety and efficacy of an antiviral drug, DAS181, as a possible treatment for hospitalized patients with severe COVID-19.

15 Jul 2020

New radiopharmaceutical offers precise diagnosis and treatment of prostate cancer in preclinical studies

Researchers have developed a new pair of agents that show exceptional effectiveness for precision diagnosis and treatment of prostate cancer in preclinical studies.

14 Jul 2020

UTHealth physicians study blood pressure drug's efficiency in improving COVID-19 outcomes

An interventional therapy aimed at improving survival chances and reducing the need for critical care treatment due to COVID-19 is being investigated by physicians at The University of Texas Health Science Center at Houston.

14 Jul 2020

NIH establishes clinical trial network to test vaccines and monoclonal antibodies for COVID-19

The National Institute of Allergy and Infectious Diseases (NIAID), part of the National Institutes of Health (NIH), has established a new clinical trial network that aims to enroll thousands of volunteers in large-scale clinical trials testing a variety of investigational vaccines and monoclonal antibodies intended to protect people from COVID-19.

14 Jul 2020

Researchers develop new immunotherapy that prevents reoccurrence of breast cancer

New immunotherapy developed by researchers at Northwestern University dramatically extends the survival time of mice with triple-negative breast cancer, one of the most aggressive and difficult-to-treat forms of breast cancer.

14 Jul 2020

Single dose of tocilizumab improves survival in critically ill COVID-19 patients

Critically ill COVID-19 patients who received a single dose of a drug that calms an overreacting immune system were 45% less likely to die overall, and more likely to be out of the hospital or off a ventilator one month after treatment, compared with those who didn't receive the drug, according to a new study by a team from the University of Michigan.

14 Jul 2020

Altimmune reports positive results on intranasal COVID-19 vaccine candidate

Altimmune, Inc., a clinical-stage biopharmaceutical company, has announced positive results from the preclinical studies conducted in mice at the University of Alabama at Birmingham of its intranasal COVID-19 vaccine candidate, AdCOVID.

14 Jul 2020

New drug enables the immune system to attack ovarian cancer, TGen study shows

A drug known as SP-2577 could help enable the body's own immune system to attack ovarian cancer, according to a study led by the Translational Genomics Research Institute, an affiliate of City of Hope.

13 Jul 2020

ASC-enriched fat grafts for breast augmentation could produce superior results

Results of a clinical trial released today in STEM CELLS Translational Medicine indicates that breast augmentation in patients treated with fat grafts enriched with autologous adipose-derived stem cells (ASCs) had significantly superior results compared to those treated with non-enriched grafts.

9 Jul 2020

Clinical Trial News and Research

A safer treatment harnesses the body's cancer-fighting T cells to fight multiple myeloma

Clinical trial shows CAR-T cell therapy can be used for treating Hodgkin lymphoma

New approach is more effective in treating certain blood cancers

Fusion protein found to effective at treating pulmonary arterial hypertension

UC Davis Health tests new antibody combination as potential treatment for COVID-19

Scientists gain insights into how parasitic bacterium gives rise to lesions

New, promising CAR T cell therapy results in exceptional patient recovery

Investigational COVID-19 vaccine is safe, generates neutralizing antibody activity in healthy adults

Keck Medicine of USC participates in clinical trial to test antiviral drug as potential COVID-19 treatment

New radiopharmaceutical offers precise diagnosis and treatment of prostate cancer in preclinical studies

UTHealth physicians study blood pressure drug's efficiency in improving COVID-19 outcomes

NIH establishes clinical trial network to test vaccines and monoclonal antibodies for COVID-19

Researchers develop new immunotherapy that prevents reoccurrence of breast cancer

Single dose of tocilizumab improves survival in critically ill COVID-19 patients

Altimmune reports positive results on intranasal COVID-19 vaccine candidate

New drug enables the immune system to attack ovarian cancer, TGen study shows

ASC-enriched fat grafts for breast augmentation could produce superior results

Novel precision medicine targets cancer's DNA defenses

Developments in Engineered T Cells for Type 1 Diabetes

Study shows MMR vaccine may protect against COVID-19 symptoms

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