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Research Uncovers the Biology Underpinning a Rare Genetic Mutation Linked to Painlessness

The biology underpinning a rare genetic mutation that allows its carrier to live virtually pain-free, heal more rapidly and experience reduced anxiety and fear, has been uncovered by new research from UCL.

24 May 2023

Researchers Develop AI Method to Predict Small Molecule Substrates of Enzymes

Enzymes are the molecule factories in biological cells. However, which basic molecular building blocks they use to assemble target molecules is often unknown and difficult to measure.

23 May 2023

Key Event that Controls the Timing of the Biological Clock Identified

Molecular clocks in our cells synchronize our bodies with the cycle of night and day, cue us for sleep and waking, and drive daily cycles in virtually every aspect of our physiology. Scientists studying the molecular mechanisms of our biological clocks have now identified a key event that controls the timing of the clock.

23 May 2023

A High-Throughput Assay for Identifying and Validating ECHS1 Enzyme Genetic Variants

The enzyme variations of mitochondrial enoyl-CoA hydratase short-chain 1 (ECHS1) are dysfunctional. In Japan, they are mostly responsible for mitochondrial disease.

19 May 2023

Pancreatic Cancer Cells Use a New Nutrient Source to Grow, Study Finds

Researchers at the University of Michigan Rogel Cancer Center have discovered a new nutrient source that pancreatic cancer cells use to grow.

18 May 2023

Glycosylation Enzyme Regulates the Formation of Neurons and Astrocytes From Neural Stem Cells

The MGAT5 glycosylation enzyme plays a crucial role in brain development, according to a study by University of California, Irvine researchers, a discovery that may contribute to new therapeutic purposes for neural stem cells.

17 May 2023

Study Provides a New Picture of How Bacterial Cells Repair Faulty DNA

A new study adds to an emerging, radically new picture of how bacterial cells continually repair faulty sections of their DNA.

17 May 2023

Chemical Modification Improves Non-Viral Gene Editing as Well as a New Type of DNA Repair

Gene editing is a powerful method for both research and therapy. Since the advent of the Nobel Prize-winning CRISPR/Cas9 technology, a quick and accurate tool for genome editing discovered in 2012, scientists have been working to explore its capabilities and boost its performance.

12 May 2023

Prime Editing System Could Accelerate the Study of Cancer-Linked Mutations

Genomic studies of cancer patients have revealed thousands of mutations linked to tumor development.

12 May 2023

Common Food Additives may Have Negative Effects on Your Gut Health

Common food additives known as metal oxide nanoparticles may have negative effects on your gut health, according to new research from Binghamton University, State University of New York and Cornell University.

10 May 2023

Breakthrough "Gene Silencing" Technology Could Revolutionize the Development of DNAzymes

Researchers from the University of California, Irvine have developed a DNA enzyme – or DNAzyme – that can distinguish between two RNA strands inside a cell and cut the disease-associated strand while leaving the healthy strand intact.

9 May 2023

Remodeling in the Cell Membrane Alters Enzyme Activity Involved in Alzheimer’s

Adding long-chain fatty acids can thicken cell membranes and alter the activity of a key enzyme, as LMU scientists have demonstrated in cell cultures.

5 May 2023

Study Uncovers Cancer-Like Changes in Mitochondrial Disease of Newborns

A study found that a mitochondrial disease of newborns shows cancer-like changes in proliferating cells, causing tissues to age prematurely.

4 May 2023

Researchers Map GCK Gene Variants to Better Diagnose Hereditary Diseases

Researchers at the Department of Biology, University of Copenhagen, have now contributed to solving this problem for a specific gene called GCK. The study has just been published in Genome Biology.

4 May 2023

Understanding the Process of Gene Regulation Using Cryogenic Electron Microscopy

LMU researchers show detailed displacement process of TBP transcription factor from DNA by Mot1 enzyme.

2 May 2023

Genome Sequencing of 'Lablab Bean' Paves Way for Wider Cultivation of the African Crop

An international team of researchers has fully sequenced the genome of a climate-resilient bean that could bolster food security in drought-prone regions.

2 May 2023

Development of Biocomputing’s Third Approach: Trumpet

Biological computing or biocomputing can revolutionize computers and medicine from early diagnosis and internal cure of diseases to futuristic applications like expanding human memory.

2 May 2023

Csx28 Membrane Protein Enhances CRISPR's Anti-Viral Defense

CRISPR achieved scientific popularity for its capacity to quickly and precisely edit genes. At the core, however, CRISPR systems are immune systems that aid bacteria to safeguard themselves from viruses through targeting and abolishing viral RNA and DNA.

28 Apr 2023

Getting Insights into Parkinson’s Patients’ Brain Cells Through Stem Cell Research

When the first symptoms of Parkinson’s disease are experienced by a patient, the disease has been evolving for a long period, and the patient might already have lost half of a certain kind of nerve cells in the brain.

27 Apr 2023

New, Improved Dual Version of Living Yeast Biosensor to Detect All Peptide Variants

Biosensors-;sensors that can detect biological samples-;are powerful tools for understanding the function, composition, and structure of biochemical molecules.

26 Apr 2023

Enzyme News and Research

Research Uncovers the Biology Underpinning a Rare Genetic Mutation Linked to Painlessness

Researchers Develop AI Method to Predict Small Molecule Substrates of Enzymes

Key Event that Controls the Timing of the Biological Clock Identified

A High-Throughput Assay for Identifying and Validating ECHS1 Enzyme Genetic Variants

Pancreatic Cancer Cells Use a New Nutrient Source to Grow, Study Finds

Glycosylation Enzyme Regulates the Formation of Neurons and Astrocytes From Neural Stem Cells

Study Provides a New Picture of How Bacterial Cells Repair Faulty DNA

Chemical Modification Improves Non-Viral Gene Editing as Well as a New Type of DNA Repair

Prime Editing System Could Accelerate the Study of Cancer-Linked Mutations

Common Food Additives may Have Negative Effects on Your Gut Health

Breakthrough "Gene Silencing" Technology Could Revolutionize the Development of DNAzymes

Remodeling in the Cell Membrane Alters Enzyme Activity Involved in Alzheimer’s

Study Uncovers Cancer-Like Changes in Mitochondrial Disease of Newborns

Researchers Map GCK Gene Variants to Better Diagnose Hereditary Diseases

Understanding the Process of Gene Regulation Using Cryogenic Electron Microscopy

Genome Sequencing of 'Lablab Bean' Paves Way for Wider Cultivation of the African Crop

Development of Biocomputing’s Third Approach: Trumpet

Csx28 Membrane Protein Enhances CRISPR's Anti-Viral Defense

Getting Insights into Parkinson’s Patients’ Brain Cells Through Stem Cell Research

New, Improved Dual Version of Living Yeast Biosensor to Detect All Peptide Variants

Quorum Bio: Where Synthetic Biology Meets Sustainable Farming

Diagnostic Biochips: Pioneering Brain Research Tools for the Future

Commercializing Innovation in a Life Sciences Ecosystem

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