Lupus News and Research

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Systemic lupus erythematosus (SLE), also called lupus, is an autoimmune disorder characterized by the immune system attacking the body's own tissues and organs, leading to inflammation and damage. The severity of the disease varies, from mild cases only involving the skin to severe cases affecting multiple organs, including the brain. Lupus sufferers experience flares, or intervals of active disease, and remissions in disease. The disease most predominantly occurs in women of childbearing age, but also affects children, adolescents, and men. While the cause of lupus is still unknown, various genetic, environmental, and infectious causes have been associated with its development. Current treatments for lupus vary depending on the extent of the disease, and may change over time. Some medications used to ease symptoms include nonsteroidal anti-inflammatory drugs, antimalarial drugs, corticosteroids, and immunosuppressive medications, though many of these drugs carry their own risks.
Impact of Rare Disease Mutation Could Extend to More Prevalent Conditions

Impact of Rare Disease Mutation Could Extend to More Prevalent Conditions

CRISPR Screening Reveals Peptide in Human RNA Regulating Inflammation

CRISPR Screening Reveals Peptide in Human RNA Regulating Inflammation

Study Reveals Structure of Two Nucleic Acid-Degrading Enzymes

Study Reveals Structure of Two Nucleic Acid-Degrading Enzymes

Overlooked Sequence in Immunology Protein Holds Promise for New Autoimmune Therapies

Overlooked Sequence in Immunology Protein Holds Promise for New Autoimmune Therapies

Relation Between Faulty DNA Disposal System and Inflammation

Relation Between Faulty DNA Disposal System and Inflammation

Immune System Surprise: "Junk Cells" Show Ability to Fight Malaria

Immune System Surprise: "Junk Cells" Show Ability to Fight Malaria

The Exclusome, A New Mammalian "Container"

The Exclusome, A New Mammalian "Container"

Study Delves Deeper into Understanding How Humans Behave

Study Delves Deeper into Understanding How Humans Behave

T Cells can Fuel Their Ability to Attack Tumors

T Cells can Fuel Their Ability to Attack Tumors

New Clinical RNA Sequencing Platform Helps Facilitate Research into Rare Genetic Conditions

New Clinical RNA Sequencing Platform Helps Facilitate Research into Rare Genetic Conditions

Additional therapeutic maneuver may be needed to stop some metastasized tumors                                               Cancer That...

Additional therapeutic maneuver may be needed to stop some metastasized tumors Cancer That...

New therapeutic approaches to treat autoimmune diseases using a metabolite

New therapeutic approaches to treat autoimmune diseases using a metabolite

Investigating the potential cellular effects of C-reactive protein

Investigating the potential cellular effects of C-reactive protein

Pentamer shape of C-reactive protein can suppress the immune response in inflammatory disease

Pentamer shape of C-reactive protein can suppress the immune response in inflammatory disease

Researchers track a specialized garbage disposal cell inside lymph nodes for the first time

Researchers track a specialized garbage disposal cell inside lymph nodes for the first time

LLNL set off to develop vaccines to treat rheumatoid arthritis and lupus

LLNL set off to develop vaccines to treat rheumatoid arthritis and lupus

MicroRNA’s influence on lupus disease inflammation

MicroRNA’s influence on lupus disease inflammation

Detecting the extent of natural selection over time

Detecting the extent of natural selection over time

Improving potential of cellular therapies with CAR T therapy

Improving potential of cellular therapies with CAR T therapy

Genetic predisposition for SLE protective against severe COVID-19 infection

Genetic predisposition for SLE protective against severe COVID-19 infection

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