Metabolism News and Research

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Metabolism is the means by which the body derives energy and synthesizes the other molecules it needs from the fats, carbohydrates and proteins we eat as food, by enzymatic reactions helped by minerals and vitamins.

New Protein Identified as Regulator of Mitochondrial Calcium Transport

Calcium transport into and out of mitochondria – the powerhouses of cells – is central to cellular energy production and cell death.

9 Apr 2025

Genomic and Geological Timeline of Bacterial Evolution

Scientists at the University of Queensland have contributed to the development of a precise timeline for bacterial evolution, indicating that some bacteria used oxygen long before they evolved the ability to manufacture it through photosynthesis.

4 Apr 2025

ER-Stressed Fat Cells Influence Liver Function Through Lipid Signaling

The endoplasmic reticulum (ER) is the portion of the cell responsible for manufacturing and folding proteins. Proteins are essential for a wide range of cellular functions-as enzymes, transporters, hormones, antibodies, receptors, and more.

2 Apr 2025

New Scientific Article in Nature Linking the Potential Use of NeuroRestore ACD856 for the Treament of Obesity

AlzeCure Pharma AB (publ) (FN STO: ALZCUR), a pharmaceutical company that develops candidate drugs for diseases affecting the nervous system, focusing on Alzheimer's disease and pain, announced today that an article has been published in Nature suggesting the use of NeuroRestore ACD856 in the treatment of obesity.

2 Apr 2025

Study Identifies Mechanisms Regulating Nuclear Pore Complexes in Cells

The nuclei in our cells are miniature warehouses safeguarding the genetic blueprint for the body's biologic machinery.

1 Apr 2025

AI Brings Brain Metabolism to Life in 3D with MetaVision3D

The MetaVision3D tool transforms 2D tissue sections into 3D brain metabolome models, offering critical insights into metabolism and neurological diseases.

31 Mar 2025

Intermittent Fasting Alters Serotonin Levels to Boost Male Mice's Libido

Long-term fasting in 24-hour cycles increases the sex drive of male mice by lowering the concentration of the neurotransmitter serotonin in the brain.

29 Mar 2025

Horses' Unique Genetic Adaptation for Superior Endurance Revealed

Researchers have revealed a secret behind horses' exceptional endurance – a mutation in the KEAP1 gene that boosts energy production while protecting against cellular oxidative stress.

28 Mar 2025

Hidden Causal Interaction Network Found in Cervical Cancer Cells

A Japanese research team has discovered a novel global cooperative phenomena of cell interactions in cervical cancer cells. Their findings suggest that the cells are metabolically connected in a functional network.

26 Mar 2025

New Discovery Sheds Light on C. Diff's Survival Mechanism in the Gut

The pathogen C. diff - the most common cause of health care-associated infectious diarrhea - can use a compound that kills the human gut's resident microbes to survive and grow, giving it a competitive advantage in the infected gut.

26 Mar 2025

Fusion Proteins Offer New Path for Antibody Generation in Disease Research

The Food and Drug Administration has approved more than 100 monoclonal antibodies to treat a range of diseases. Other antibodies are used by physicians to diagnose conditions or by scientists to advance research projects.

26 Mar 2025

Researchers Create Yeast Consortium for Efficient Lignan Biosynthesis

Lignans are low molecular weight polyphenolic compounds with important antitumor and antiviral properties.

25 Mar 2025

Pregnancy Triggers Small Intestine Growth in Mice

Researchers at the Francis Crick Institute have found that the small intestine grows in response to pregnancy in mice. This partially irreversible change may help mice support a pregnancy and prepare for a second.

20 Mar 2025

Pig Retinal Organoids Offer Promising Model for Stem Cell-Based Vision Therapies

Inside the human eye, the retina is made up of several types of cells, including the light-sensing photoreceptors that initiate the cascade of events that lead to vision.

14 Mar 2025

Extrachromosomal DNA Discovered as a Hidden Factor in Pancreatic Cancer Survival

Pancreatic cancer is one of the deadliest cancers worldwide, with a five-year survival rate of 13%.

14 Mar 2025

SRS Microscopy Unlocks New Insights into Cellular Metabolism and Disease

Cellular metabolism plays a critical role in various physiological and pathological processes. High resolution imaging of intracellular metabolic activities is crucial for understanding many biological pathways, and for facilitating disease prognosis and treatment assessment.

14 Mar 2025

Fruit Fly Study Reveals Temperature's Role in Brain Development and Behavior

The rate of development of poikilothermic animals, such as insects, fish, and reptiles, is determined by environmental temperature.

14 Mar 2025

Researchers Create 'Colocatome' to Study Tumor Cell Interactions

Even cells experience peer pressure. Scientists have long studied the ins and outs of cancer cells to learn more about the disease, but they're increasingly finding that noncancerous cells near the cancer cells exert a powerful influence over a tumor's trajectory.

13 Mar 2025

Can We Engineer Crops to Withstand Climate Change and Increasing Temperatures?

Investigating heat stress in crops, this review highlights genetic adaptations and CRISPR techniques to develop resilient varieties for sustainable agriculture.

12 Mar 2025

Scientists Develop Off-the-Shelf Vascular Grafts Using Stem Cells

Zhang, J., et al. (2025) Small-diameter artery grafts engineered from pluripotent stem cells maintain 100% patency in an allogeneic rhesus macaque model. Cell Reports Medicine. doi.org/10.1016/j.xcrm.2025.102002.

12 Mar 2025