Metabolism News and Research

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Metabolism is the means by which the body derives energy and synthesizes the other molecules it needs from the fats, carbohydrates and proteins we eat as food, by enzymatic reactions helped by minerals and vitamins.

Novel targeted therapy blocks critical metabolic pathways in cancer cells

Scientists have designed a new targeted therapy, known as POMHEX, which inhibits vital metabolic pathways in tumor cells containing specific genetic defects.

24 Nov 2020

Adipose tissue plays key role in the aggravation of COVID-19

There is growing evidence that adipose tissue plays a key role in the aggravation of COVID-19. One of the theories under investigation is that fat cells (adipocytes) act as a reservoir for SARS-CoV-2 and increase viral load in obese or overweight individuals.

23 Nov 2020

High-protein total diet replacements may be a promising strategy to combat obesity

According to the World Health Organization, obesity has nearly tripled worldwide since 1975. In 2016, for example, more than 1.9 billion adults were categorized as overweight. Of these, more than 650 million had obesity.

19 Nov 2020

Study reveals metabolic signaling pathways that influence key immune cells

Effector regulatory T cells, also known as eTreg cells, are a specialized subset of white blood cells that maintain the immune system.

18 Nov 2020

Clostridium bacteria can help convert waste gas into valuable compounds

Several branches of industry discharge waste gases that contain mostly carbon dioxide and carbon monoxide.

17 Nov 2020

New strategy can speed up the development of bio-based products

Scientists have accomplished a major breakthrough by altering a microorganism to efficiently create a target compound using CRISPR-based gene editing.

10 Nov 2020

Low levels of hydrogen peroxide can slow down cell aging

High levels of reactive oxygen species, called oxidants, are detrimental to cells in all organisms and have been associated with ageing.

10 Nov 2020

Dietary supplement helps to partially prevent fatty liver disease in rats

A recent study by researchers at the University of Jyväskylä was successful in partially preventing fatty liver disease in rats.

5 Nov 2020

Novel computational method quantifies the coordination level between different genes

Although all humans share similar changes during aging such as gray hair, wrinkles, and a general decline in function, aging is considered to be the result of a cellular wear-and-tear process due to accumulated random damage, such as genetic mutations or DNA structural damage.

4 Nov 2020

Computational method reveals a new hallmark of aging

While all human beings share changes during aging, like wrinkles, gray hair, and a general drop in function, aging is assumed to be the outcome of a cellular process.

4 Nov 2020

Study identifies genes and molecular pathways most sensitive to chemical exposures

A University of Massachusetts Amherst environmental health scientist has used an unprecedented objective approach to identify which molecular mechanisms in mammals are the most sensitive to chemical exposures.

30 Oct 2020

Sodium bicarbonate can reprogram T cells in leukemia patients

Scientists have discovered that sodium bicarbonate - also known as baking soda or bicarbonate of soda - can reprogram T cells in leukemia patients to resist the immune-suppressing effects of cancer cells, which can drive leukemia relapse after stem cell transplants.

29 Oct 2020

Why a diet high in flavanols may lower blood pressure

In this interview, AZoLifeSciences speaks to Professor Kuhnle about his latest research which showed that a diet high in flavanols may lower blood pressure.

28 Oct 2020

Specific metabolites can predict COVID-19 mortality

A new study from Lawson Health Research Institute, Western University and University of Alberta suggests that COVID-19 affects the human body's blood concentration levels of specific metabolites - small molecules broken down in the human body through the process of metabolism.

28 Oct 2020

Cellular senescence variations may help control health and onset of age-related diseases

Researchers from Kumamoto University, Japan have proposed that cellular senescence variations during the aging process could lead to control of health and onset of age-related diseases.

27 Oct 2020

Global "BiteMap" shows how climate change could shape marine food webs

Where are small marine animals most vulnerable to getting eaten? The answer has big consequences for coastal ecosystems, where most of the world's fishing takes place, since predators can radically change underwater communities.

27 Oct 2020

Ketogenic diets can prevent or reverse heart failure caused by metabolic process

Research from Saint Louis University finds that high fat or "ketogenic" diets could completely prevent, or even reverse heart failure caused by a metabolic process.

27 Oct 2020

Dietary supplement can support immune system to combat SARS-CoV-2 infections

SPIN (SPermidin and eugenol INtegrator for the contrasting incidence of coronavirus in EU population) is a European project powered by EIT Food that is currently developing a dietary supplement supporting the function of the immune system in the fight against SARS-CoV-2 infections in the population at high risk.

22 Oct 2020

Study finds significant link between flavanol consumption and lower blood pressure

People who consume a diet including flavanol-rich foods and drinks, including tea, apples and berries, could lead to lower blood pressure, according to the first study using objective measures of thousands of UK residents' diet.

22 Oct 2020

New DNA-cutting tool could advance gene editing for novel treatments

Gene editing for the development of new treatments, and for studying disease as well as normal function in humans and other organisms, may advance more quickly with a new tool for cutting larger pieces of DNA out of a cell's genome, according to a new study by UC San Francisco scientists.

21 Oct 2020