in vitro News and Research

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Human cells absorb less protein from plant-based meat than from chicken

Protein-rich plants, like soybeans, are common ingredients, but it is unknown how much of the nutrient gets absorbed in human cells.

27 Jun 2022

Researchers reveal how blood serum impacts the survival and metabolism of bacteria

In hospitals, the Staphylococcus aureus bacteria can be transported from the skin or nasal cavity into open wounds and, possibly, the bloodstream, posing a fatal hazard. Staph infections killed over 20,000 Americans in 2017, according to the Centers for Disease Control and Prevention.

20 Jun 2022

Study reveals possibility of changing the identity of synapses through enzymatic means

As you're reading this sentence, the cells in your brain, called neurons, are sending rapid-fire electrical signals between each other, transmitting information.

14 Jun 2022

ZDHHC18-mediated MDH2 palmitoylation upholds mitochondrial respiration and boosts ovarian cancer malignancy

To drive anabolic processes, epithelial ovarian cancer (EOC) is heavily reliant on the tricarboxylic acid (TCA) cycle and oxidative phosphorylation.

13 Jun 2022

Axol Bioscience introduces CiPA-validated human stem cell-derived ventricular cardiomyocytes to help improve drug discovery

Axol Bioscience Ltd. (Axol), an established provider of iPSC-derived cells, media, and characterization services for life science discovery, today announced that its human induced pluripotent stem cell (iPSC)-derived ventricular cardiomyocytes have undergone comprehensive in vitro pro-arrhythmia assay (CiPA) validation.

From Axol Bioscience Ltd 8 Jun 2022

Research shows how current drugs impact bacterial physiology

Tuberculosis is a stubborn disease caused by even more stubborn bacteria. While many bacterial infections clear up within days of taking antibiotics, TB can take up to six months to clear up and, in some cases, never leave the human body. In 2020, it claimed 1.5 million lives, second only to COVID-19 in terms of infectious disease deaths.

1 Jun 2022

Study highlights the interaction between single-stranded DNA and the linker histone H1

Human DNA is neatly locked in place around a central disc in the tight quarters of the cell nucleus by H1 linker histone that helps shepherd DNA into the tidy chromatin fibers that make up chromosomes. The linker histone, on the other hand, is much more than a protein clip.

31 May 2022

Researchers create human cornea-on-a-chip to check the therapeutic effect of MSC exosomes on corneal disorders

Ophthalmologists and researchers have been looking into mesenchymal stem cells (MSCs) with regenerative and differentiation capacities as a potential therapy option for corneal disorders.

30 May 2022

Researchers analyze gut microbiome with dietary fiber through ecological model

Dietary fiber is known to be beneficial to gut health. However, it has a wide range of effects on the composition and metabolic activity of the gut microbiome.

27 May 2022

Study shows polymersome can effectively deliver PARP1 siRNA to treat breast cancer

Small interfering RNAs, or siRNAs, have the potential to cure tumors by targeting knocking down oncogenes that drive tumor development while avoiding the damage associated with chemotherapy.

25 May 2022

Researchers develop primitive endoderm stem cells in mice

RIKEN scientists have extracted and grown stem cells that give way to the mouse yolk sac for the first time in the laboratory, boosting the potential of generating mouse embryos from stem cells in the coming years.

23 May 2022

Rapidly growing nanotechnology firm launches new identity as MIP Discovery

MIP Diagnostics, a leading UK nanotechnology firm has today rebranded to MIP Discovery as the business continues its expansion within the healthcare sector.

From MIP Discovery 19 May 2022

New research identifies a destination for zinc chaperone protein's deliveries

Most people don't think much about zinc. But all living things need zinc for survival. This trace element helps many proteins fold into the right shapes to do their jobs.

18 May 2022

Research sheds light on new options for organ cultivation in vitro

How do human cells organize themselves to give the organs their ultimate shape? The solution is morphogenesis, a collection of systems that controls their spatial distribution throughout embryonic development. In this sector, a team from the University of Geneva (UNIGE) recently discovered an unexpected discovery: when a tissue curves, the volume of the cells that makes it up grows rather than decreases.

18 May 2022

New supramolecular CRISPR–Cas9 carrier supports much effective genome editing

Clustered regularly interspaced short palindromic repeats (CRISPR) and their accompanying protein, CRISPR-associated protein 9 (Cas9), several years ago, made international news as a game-changing genome editing system.

18 May 2022

Research sheds light on mechanism for skin cell death, likely to help treat cancer

Researchers at Emory University have uncovered a mechanism for skin cell death that might lead to novel therapies for “flesh-eating” infections, alopecia, hives, and possibly even melanoma, the deadliest type of skin cancer.

18 May 2022

bit.bio launches Huntington’s disease human cell model

First neurodegenerative disease model launched from bit.bio's new ioDisease Model portfolio.

From bit.bio 10 May 2022

Enzymes found in capybara gut can promote the application of agroindustrial waste

One option to reduce dependence on oil and other fossil fuels is to transform agroindustrial waste into molecules of interest to society, like biofuels and biochemicals.

10 May 2022

New 3D in vitro model reveals the origins of human spine

The spinal column is the central supporting structure of the skeleton in all vertebrates. Not only does it provide a place for muscles to attach, it also protects the spinal cord and nerve roots. Defects in its development are known to cause rare hereditary diseases.

28 Apr 2022

CN Bio introduces PhysioMimix NASH ‘in-a-box’ reagent kit

First product within new ‘in-a-box’ range, which harnesses next-generation, human-relevant Liver-on-a-Chip technology to improve the accuracy and efficiency of NASH drug discovery.

From CN Bio Innovations Limited 26 Apr 2022

in vitro News and Research

Human cells absorb less protein from plant-based meat than from chicken

Researchers reveal how blood serum impacts the survival and metabolism of bacteria

Study reveals possibility of changing the identity of synapses through enzymatic means

ZDHHC18-mediated MDH2 palmitoylation upholds mitochondrial respiration and boosts ovarian cancer malignancy

Axol Bioscience introduces CiPA-validated human stem cell-derived ventricular cardiomyocytes to help improve drug discovery

Research shows how current drugs impact bacterial physiology

Study highlights the interaction between single-stranded DNA and the linker histone H1

Researchers create human cornea-on-a-chip to check the therapeutic effect of MSC exosomes on corneal disorders

Researchers analyze gut microbiome with dietary fiber through ecological model

Study shows polymersome can effectively deliver PARP1 siRNA to treat breast cancer

Researchers develop primitive endoderm stem cells in mice

Rapidly growing nanotechnology firm launches new identity as MIP Discovery

New research identifies a destination for zinc chaperone protein's deliveries

Research sheds light on new options for organ cultivation in vitro

New supramolecular CRISPR–Cas9 carrier supports much effective genome editing

Research sheds light on mechanism for skin cell death, likely to help treat cancer

bit.bio launches Huntington’s disease human cell model

Enzymes found in capybara gut can promote the application of agroindustrial waste

New 3D in vitro model reveals the origins of human spine

CN Bio introduces PhysioMimix NASH ‘in-a-box’ reagent kit

Integrating Software and Solutions to Accelerate Antibody Discovery

CHEMUK 2022: the IBioIC on Industrial Biotechnology

Tackling Food Waste to Protect Our Planet

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