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Newly discovered enzyme tells specific molecules precisely how to arrange themselves

Just as a choreographer's notation tells a dancer to strike a particular pose, an enzyme newly discovered by Rice University scientists is able to tell specific molecules precisely how to arrange themselves, down to the angle of single hydrogen bonds.

30 Jan 2023

AI develops first-ever functional artificial protein

Scientists have developed an AI system that can produce artificial enzymes from scratch. Even though several of these enzymes’ artificially generated amino acid sequences differed noticeably from those of any known natural protein, they nonetheless performed as well in laboratory testing as those found in nature.

27 Jan 2023

Ubiquigent collaborates with University of Glasgow on translational structural biology to accelerate drug discovery within the (de)ubiquitylation field

Ubiquigent Limited (Ubiquigent), a drug discovery and development company harnessing novel deubiquitinase (DUB) modulators as new therapeutics for areas of high unmet medical need, today announced it is supporting a Master’s student at the University of Glasgow (UoG) to undertake a research project on USP30, a DUB implicated in neurodegenerative, renal, and cardiovascular diseases.

From Ubiquigent Limited 23 Jan 2023

Expanding the CRISPR-based toolbox for extensive genome engineering

Researchers from North Carolina State University describe a variety of CRISPR-Cas systems-based molecular tools to rewrite, rather than just edit, significant portions of an organism’s DNA.

23 Nov 2022

IBS team uncovers new antiviral compounds derived from two Korean native plants

Codonopsis lanceolata, more commonly referred to as "deodeok", is used as a medicinal herb in South Korea.

14 Nov 2022

New electrochemical sensing platform holds promise for monitoring perfusable vascular networks

The costliness of drug development and the limitations of studying physiological processes in the lab are two separate scientific issues that may share the same solution.

9 Nov 2022

The Native Antigen Company expands its range of Omicron antigens to include BA.5 variant

The Native Antigen Company (part of LGC Clinical Diagnostics), one of the world’s leading suppliers of reagents that enables research into vaccines and diagnostics for emerging and endemic infectious diseases, today announced the commercial launch of its latest SARS-CoV-2 antigens for the newly designated Omicron BA.5 variant.

From The Native Antigen Company 7 Nov 2022

New bioprinting platform to replicate tumors in 3D spheroids

Bowel cancer patients could in future benefit from a new 3D bioprinting technology which would use their own cells to replicate the complex cellular environment of solid tumors in 3D models.

3 Nov 2022

New approach to clear early stage pre-cancerous tumor cells

A novel method of reprogramming the immune cells to shrink or destroy cancer cells has been demonstrated to work in melanoma, a difficult to treat and destructive skin cancer.

1 Nov 2022

Metabolite from pomegranate to boost immune cells that fight tumors

Researchers from the Georg-Speyer-Haus in Frankfurt am Main, Germany, and Goethe University Frankfurt have succeeded in developing a new strategy for the treatment of colorectal cancer as part of an interdisciplinary initiative of the LOEWE Center Frankfurt Cancer Institute (FCI).

28 Oct 2022

Potential SARS-CoV-2 therapy based on banana protein

A study praising the development of a potential treatment that might be applied to combat all recognized influenza strains was published online on January 13th, 2020.

25 Oct 2022

Black death and the development of immune genes

The Black Death, which wiped off up to 50% of the European population in less than five years, was the single-worst mortality catastrophe in recorded history.

21 Oct 2022

An accurate overview of gene activity could provide targeted therapies

Normal gene activity in the afflicted cells is changed during pathological events. Therefore, obtaining a precise picture of gene activity could hold the key to the creation of new, targeted therapies.

18 Oct 2022

Research team outlines three-step technique that lets human body defend against Hep B

A team from the University of Geneva (UNIGE) has unraveled the precise operation of this defensive mechanism after finding a crucial protein complex that is active when our body is infected by the virus, paving the path for novel treatment targets.

5 Oct 2022

The exchange of nutrients between the mother and fetus mirrored by ‘placenta-on-a-chip’

Plasmodium falciparum infections can result in placental malaria, which can have serious consequences for both mother and child. Nearly 200,000 newborn fatalities annually from placental malaria, primarily as a result of low birth weight, as well as 10,000 maternal deaths.

27 Sep 2022

The biological advantages of sperm swimming in groups

Sperm actually swim better together when they are swimming against the current. Contrary to common belief, spermatozoa frequently cooperate to go through the female reproductive system in a variety of mammalian species, contradicting the notion that the fastest and fittest male reproductive cell wins the fertilization race.

22 Sep 2022

Researchers use bacteria to create artificial cells that function like living cells

Researchers have used bacteria to create sophisticated synthetic cells that imitate the activity of genuine cells.

15 Sep 2022

Study provides insight into how birds decide their sex

A study team has examined chicken germ cells using RNA-sequencing to anticipate the mechanism that determines the sex to better understand the process of the sex determination in the germ cell.

12 Sep 2022

Using human saliva to treat infections that are resistant to antibiotics

Tens of millions of individuals throughout the world suffer from antibiotic resistance every year. The CDC reports that more than 35,000 people die each year as a result of more than 2.8 million antibiotic-resistant infections that take place there each year.

2 Sep 2022

The complex link between pancreatic malformations and the “dark genome”

For the first time, scientists at the Centre for Genomic Regulation (CRG) have discovered a DNA sequence that is essential for pancreatic development and function.

25 Aug 2022