Biochemistry

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Single-Molecule Optical Tweezers Visualize Real-Time Dynamic Protein and DNA Interactions

A protein that's essential to every cell's ability to turn off unnecessary genes is well known for its key function of compacting genes and its connection to cancer when it undergoes mutation.

1 Oct 2026

Kupffer Cells Increase Apolipoprotein Secretion in Response to Indigestible Plastics

Microplastics appear capable of significantly impairing the function of phagocytes in the liver, at least in mice. In turn, this disrupts the metabolism of this vital organ and increases the build-up of fat inside it. These are the key findings from a joint German-Austrian study led by the University of Bonn, details of which have now been published in the journal "Nature Metabolism."

1 Oct 2026

Gut-Derived Neutral Ceramidase Regulates MASH Through Microbial and Epithelial Signaling

Metabolic dysfunction-associated steatohepatitis (MASH) is often viewed through the lens of hepatic lipid accumulation, inflammation and fibrosis.

30 Sep 2026

Scientists Pinpoint the Brain Circuit That Regulates Metabolism

As the body’s temperature decreases, it compensates by utilizing additional energy to produce heat and stimulating the desire to eat to replenish the energy expended for warmth.

28 Sep 2026

How Feedback Mechanisms Control Neural Chaos for Stable Visual Processing

What we see appears stable, even though neuronal activity is full of irregular fluctuations. A team led by Dr Mehdi Borjkhani from ICTER has shown, using a minimal model of the primary visual cortex, that two natural feedback mechanisms can constrain chaos and reduce variability in neural activity by up to 93 percent.

23 Sep 2026

Researchers Identify Peptide That Counters Key Processes of Neurodegenerative Disorders

Alzheimer's disease and related neurodegenerative disorders are among medicine's most challenging conditions, progressively impairing memory, movement and independence. Now, researchers at the University of California San Diego School of Medicine have identified a naturally occurring peptide - a small protein fragment called catestatin (CST) - that may help counter several key processes driving neurodegeneration.

23 Sep 2026

What Drives Pregnancy Cravings? Researchers Find a Clue in the Brain

What causes intense food cravings during pregnancy? Scientists at LSU’s Pennington Biomedical Research Center, working alongside collaborators, have pinpointed a neural mechanism that may explain how pregnancy influences the desire to pursue certain highly appealing foods.

22 Sep 2026

Antidepressant Withdrawal, Not Relapse, Linked to Mood Changes

When people stop taking antidepressants they can feel terrible – their mood can plummet and anxiety can spike.

22 Sep 2026

Blocking Mitochondrial Iron Transport Protects Cells Against Elevated Cysteine Toxicity

Cysteine is one of the main building blocks that cells use to make proteins.

22 Sep 2026

New Research Reveals Complex Protein Dynamics Within Human Red Blood Cells

They account for nearly 83% of all cells in the human body, yet red blood cells are often portrayed as little more than bags of hemoglobin ferrying oxygen from the lungs to the heart and beyond. But new research from the University of Colorado Anschutz reveals that they are vastly more complex with far reaching consequences for health, exercise and fitness.

21 Sep 2026

Research Reveals Molecular Link Between Matrix Protein Motifs and Ameloblast Organization

Tooth enamel looks simple from the outside and consists of a hard, smooth surface built to withstand years of wear.

12 Sep 2026

Study Uncovers Hidden Human "Dark Proteome" Members Across Protein Models

Hundreds of millions of proteins make up the known protein universe, but most remain largely unexplored. Inside the human body, thousands of these dark proteins remain mysteries. Scientists may know they exist, but not what they do or why they matter.

12 Sep 2026

Scientists Identify Molecular Mechanism Behind Persistent Obesity and Weight Relapse

Two enduring biological mysteries have remained unsolved for decades: why almost everyone who loses weight gains it back, no matter how they lost it, and why obesity passes from mother to child at rates that diet and environment cannot explain. Now, scientists from Harrington Discovery Institute at University Hospitals and Case Western Reserve University have identified why.

11 Sep 2026

Reprogramming Tumor Immune Microenvironment to Combat Aggressive Glioblastoma Brain Cancer

Mayo Clinic researchers have identified a potential new approach to treating glioblastoma that could help the immune system fight the aggressive brain cancer while improving the effectiveness of existing chemotherapy.

11 Sep 2026

Molecular Circuit Linking Abscisic Acid Signaling to Tanshinone Production Uncovered

Salvia miltiorrhiza, also known as Danshen, is a highly regarded traditional Chinese medicine widely used for treating cardiovascular and cerebrovascular diseases. Its medicinal properties are largely attributed to tanshinones-a group of more than 40 diterpenoid quinone compounds, including tanshinone I, tanshinone IIA, and cryptotanshinone, which predominantly accumulate in the plant's roots.

11 Sep 2026

High Resolution Chemical Maps Reveal Internal Manufacturing Layout of Herbs

Plants produce flavonoids-bioactive compounds with antioxidant, anti-inflammatory, and osteoprotective properties-through complex modification pathways.

8 Sep 2026

Research Sheds Light on Molecular Origins of Pediatric Brain Cancers

Melbourne researchers have uncovered a critical signaling pathway that controls the timing of brain development, shedding new light on how neurodevelopmental disorders may develop.

3 Sep 2026

New Platform Links Dysfunctional Biomolecular Condensates to Microcephaly and Neurodevelopment

When you add drops of oil to water, the oil and water remain separate. Within cells, biological molecules cluster together in a similar way, separating themselves from the rest of the cell. And while they don't have a membrane, they are their own distinct compartments.

3 Sep 2026

OIST Scientists Uncover Fleeting Sugar Pairs Regulating Cell Division

Acting as an armor, a scaffold, and a communication platform in one, our cells' plasma membrane lies at the heart of many crucial cellular processes.

28 Aug 2026

International Team Establishes Standardized Nomenclature For Selenosugar Research

Selenosugars are the major urinary metabolites responsible for the physiological excretion of selenium. Understanding selenium metabolism relies on accurately detecting and identifying selenosugars.

21 Aug 2026

Biochemistry

Single-Molecule Optical Tweezers Visualize Real-Time Dynamic Protein and DNA Interactions

Kupffer Cells Increase Apolipoprotein Secretion in Response to Indigestible Plastics

Gut-Derived Neutral Ceramidase Regulates MASH Through Microbial and Epithelial Signaling

Scientists Pinpoint the Brain Circuit That Regulates Metabolism

How Feedback Mechanisms Control Neural Chaos for Stable Visual Processing

Researchers Identify Peptide That Counters Key Processes of Neurodegenerative Disorders

What Drives Pregnancy Cravings? Researchers Find a Clue in the Brain

Antidepressant Withdrawal, Not Relapse, Linked to Mood Changes

Blocking Mitochondrial Iron Transport Protects Cells Against Elevated Cysteine Toxicity

New Research Reveals Complex Protein Dynamics Within Human Red Blood Cells

Research Reveals Molecular Link Between Matrix Protein Motifs and Ameloblast Organization

Study Uncovers Hidden Human "Dark Proteome" Members Across Protein Models

Scientists Identify Molecular Mechanism Behind Persistent Obesity and Weight Relapse

Reprogramming Tumor Immune Microenvironment to Combat Aggressive Glioblastoma Brain Cancer

Molecular Circuit Linking Abscisic Acid Signaling to Tanshinone Production Uncovered

High Resolution Chemical Maps Reveal Internal Manufacturing Layout of Herbs

Research Sheds Light on Molecular Origins of Pediatric Brain Cancers

New Platform Links Dysfunctional Biomolecular Condensates to Microcephaly and Neurodevelopment

OIST Scientists Uncover Fleeting Sugar Pairs Regulating Cell Division

International Team Establishes Standardized Nomenclature For Selenosugar Research

The Future of Vision Restoration With ReVision Implant

How a Single List Is Changing Visibility for Women in Science

How Avatar Medical's 3D Technology Is Transforming How We Visualize the Human Body

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