Biochemistry

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Bone-building hormone eases chronic low back pain by restoring vertebral microarchitecture

Parathyroid hormone shows promise in treating low back pain by remodeling degenerating vertebral endplates and limiting pathological sensory innervation.

12 Feb 2026

Understanding Inter-Micellar Interactions Governing Drug Nanocarriers

Polymer micelles are tiny, self-assembled particles that are revolutionizing the landscape of drug delivery and nanomedicine.

10 Feb 2026

Cells Use Protein Partnership to Manage Oxidative Stress

Cornell researchers have discovered a new way cells regulate how they respond to stress, identifying an interaction between two proteins that helps keep a critical cellular recycling system in balance.

10 Feb 2026

Powerful New Enzyme Efficiently Synthesizes RNA

From vaccines and diagnostics to emerging gene-based therapies, RNA molecules are now central to modern medicine.

10 Feb 2026

Formic Acid Drives Novel Electron Transfer in the Gut Bacteria

Researchers at Goethe University Frankfurt have discovered a surprising role for formic acid in the human gut: The small molecule acts as a kind of “taxi” for electrons – both within bacteria and, likely, also between different microorganisms.

9 Feb 2026

Rapid Enzyme Screening Unlocks Efficient Routes to Complex Pharmaceuticals

A team of biochemists at the University of California, Santa Cruz, has developed a faster way to identify molecules in the lab that could lead to more effective pharmaceuticals.

6 Feb 2026

New Insights into TRiC and Prefoldin Mechanics

Proteins are the molecular machines of cells. They are manufactured in protein factories known as ribosomes using their blueprint, or genetic information.

6 Feb 2026

Chemistry Breakthrough Improves Gene Delivery, Reduces Side Effects

Gene therapy holds the promise of preventing and curing disease by manipulating gene expression within a patient's cells.

5 Feb 2026

New Boron Compounds Enable Easier Drug Modification Without Breakdown

A major step towards simpler drug development has been taken at the University of Gothenburg. In a new study, researchers have developed stable boron-fluorine compounds that make it possible to increase the effect or reduce side effects without breaking down the medicine.

4 Feb 2026

Sugar Molecules Point to a New Weapon Against Drug-Resistant Bacteria

Australian researchers have developed a powerful new way to target deadly, drug-resistant bacteria by designing antibodies that recognize a sugar found only on bacterial cells – an advance that could underpin a new generation of immunotherapies for multidrug resistant hospital-acquired infections.

4 Feb 2026

Unusual DNA Structure i-DNA Linked to Cancer Regulation

DNA's iconic double helix does more than "just" store genetic information. Under certain conditions it can temporarily fold into unusual shapes.

3 Feb 2026

Expanding the Biosynthetic Capabilities of Microbes Using Light

Researchers are continually looking for new ways to hack the cellular machinery of microbes like yeast and bacteria to make products that are useful for humans and society.

2 Feb 2026

Lower IgG Hinge Controls Antibody Assembly and Immune Function

The lower hinge of immunoglobulin G (IgG), an overlooked part of the antibody, acts as a structural and functional control hub, according to a study by researchers at Science Tokyo.

31 Jan 2026

Understanding the Complex Biosynthetic Pathway of O-Mannose Glycans in the Brain

Gifu University scientists have uncovered how a brain-specific enzyme reshapes protein-linked sugar chains to facilitate the formation of complex glycans essential for normal brain function.

28 Jan 2026

Single Enzyme Enables Low-Cost Synthesis of All RNA Nucleotides

A single enzyme that can generate all four nucleotide triphosphates, the building blocks of ribonucleic acid (RNA), was identified by researchers at the Institute of Science Tokyo.

24 Jan 2026

New Method Designs Highly Active and Stable Enzymes

Enzymes with specific functions are becoming increasingly important in industry, medicine and environmental protection.

24 Jan 2026

DHPS Enzyme Deficiency Impairs Macrophage Development and Tissue Repair

A new study led by researchers at the Johns Hopkins Kimmel Cancer Center, its Bloomberg~Kimmel Institute for Cancer Immunotherapy and the Johns Hopkins Bloomberg School of Public Health found that an enzyme involved in protein translation is essential for circulating immune cells, called monocytes, to mature into tissue-resident macrophages, a specialized population of immune cells that maintain organ health by clearing dead cells and debris.

22 Jan 2026

Engineering Escherichia coli for Sustainable Biosynthesis of Lauryl Glucoside

By reconstructing a non-natural metabolic route in Escherichia coli, the researchers demonstrated that simple sugars can be biologically converted into lauryl glucoside through the coordinated production of its fatty alcohol precursor and a final glycosylation step.

21 Jan 2026

Mapping the Human E3 Ligase Landscape

Maintaining cellular order is a major logistical challenge: Individual mammalian cells contain billions of protein molecules, which must be synthesized, deployed, and removed with precision.

19 Jan 2026

Model Proteins Could Bring Order to Protein Science

Protein scientists could improve reproducibility and coordination across the field by rallying around a small, shared set of "model proteins," according to a new Perspective by Connecticut College chemist Marc Zimmer.

19 Jan 2026