Biochemistry

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Researchers Discover GAME15's Role in Steroidal Compound Biosynthesis

Researchers at the Max Planck Institute for Chemical Ecology have identified GAME15 as a key protein that regulates the biosynthesis of both steroidal glycoalkaloids and steroidal saponins in plants of the genus Solanum.

21 Oct 2024

Human Organoids Provide Insights Into Gut Hormone Release

A collaborative team of researchers from the Hubrecht Institute and Roche’s Institute of Human Biology has formulated strategies to identify the regulators involved in intestinal hormone secretion.

18 Oct 2024

MANF Protein Found to Boost Cellular Clean-Up and Efficiency

Researchers at McMaster University have uncovered a previously unrecognized function of a protein that helps protect cells, potentially leading to new treatments for age-related conditions and promoting healthier aging.

18 Oct 2024

Placental Protein Levels Offer Insights into Early-Onset Preeclampsia

A potentially fatal pregnancy complication, preeclampsia is characterized by persistently elevated blood pressure, which is exacerbated when it develops early in the first trimester.

15 Oct 2024

Scientists Identify Key Role of Proteasome in Cell Death

Programmed cell death protects the body against cancer and other diseases. A team of researchers led by Professor Alexander Bartelt from the Institute for Cardiovascular Prevention (IPEK) has decoded a new mechanism by which oxidative stress influences cell death.

15 Oct 2024

Researchers Discover Key Genes for Plant Stress Tolerance

New research identifies for the first time the genes that help plants grow under stressful conditions - with implications for producing more sustainable food crops in the face of global climate change.

10 Oct 2024

A Novel Approach to Detecting Adulteration in Ginseng Supplements

Rosalee Hellberg, an associate professor in Chapman University's Food Science Program, and her research team have made a significant breakthrough in the fight against adulteration in dietary supplements. Effective methods for identifying adulteration and fraud have remained elusive. Now, a new study of 50 commercially available ginseng products has found surprising results.

9 Oct 2024

Study Unravels the Mystery of Hsp70 Chaperones

Proteins control most of the body's functions, and their malfunction can have severe consequences, such as neurodegenerative diseases or cancer. Therefore, cells have mechanisms in place to control protein quality.

9 Oct 2024

Unveiling the Enzymatic Riches of Spider Venoms

Spiders, as venomous creatures, employ their chemical arsenal for prey acquisition or self-defense. Their venom contains small neurotoxins that target the central nervous system of their targets.

8 Oct 2024

The Promise of Venomous Crustaceans in Drug Development

Many animals use venoms for self-defense or hunting. The components of such venom, known as toxins, interfere with various physiological processes - which is also the reason why they are so interesting for the development of new pharmacological agents.

7 Oct 2024

New Approaches to Treating Circadian Rhythm Disorders

Researchers from the University of California and Duke-NUS Medical School have figured out how to control the human body's internal clock. It was discovered that this regulator is located exactly at the end of Casein Kinase 1 delta (CK1δ), a protein that sets the pace for circadian rhythm, or internal biological clock, which regulates sleep-wake cycles and other daily activities.

7 Oct 2024

Harnessing Bioluminescence for Noninvasive Brain Activation

Researchers at the University of Rochester have demonstrated a noninvasive technique called bioluminescent optogenetics, or BL-OG, that uses light to stimulate brain neurons.

4 Oct 2024

Owlstone Medical and FDA Join Forces for Volatile Organic Compound Identification

Owlstone Medical (“Owlstone”), the global leader in Breath Biopsy® for applications in early disease detection and precision medicine, today announced it has entered into a Research Collaboration Agreement with the FDA’s Center for Devices and Radiological Health (“CDRH”) - Office of Science and Engineering Laboratories (OSEL).

4 Oct 2024