Biochemistry

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New signaling pathway prevents the overproduction of RNA-protein complexes

Neurodegenerative diseases, such as various forms of senile dementia or amyotrophic lateral sclerosis (ALS), have one thing in common: large amounts of certain RNA-protein complexes (snRNPs) are produced and deposited in the nerve cells of those affected - and this hinders the function of the cells.

26 Feb 2021

Combination technique could efficiently regulate specific cell behaviors

CRISPR is a genetic tool that has been compared with molecular scissors for its potential to cut out and substitute the genetic code inside the DNA.

25 Feb 2021

Study reveals new functions of ENDOU enzymes

The majority of organisms feature the series of ENDOU enzymes, but despite this fact, the functions of these enzymes have not been properly understood.

25 Feb 2021

Neuronal and glial circuits form loosely coupled super-network within the brain

Tohoku University scientists have shown that neuronal and glial circuits form a loosely coupled super-network within the brain.

25 Feb 2021

Reducing salt potentially maintains Parmigiano Reggiano cheese's texture and flavor

Aged cheeses pack a punch of nutty, sharp flavor. Before they're fully mature, aged cheeses are either waxed or placed in brine for weeks to create a natural rind. However, the high salt content in brined cheeses deters some consumers.

25 Feb 2021

Mycorrhizal fungi can control the emission of N2O from agricultural soil

One of the most significant greenhouse gases that cause global warming is nitrous oxide (N2O).

24 Feb 2021

Microfluidic chip and AI-based microscope help measure hemoglobin levels

Blood count is a test that is often performed to determine the health of patients and generally involves an estimation of the concentration of hemoglobin.

24 Feb 2021

Oxidation processes play major role in the atmosphere and in combustion

Alkanes, an important component of fuels for combustion engines and an important class of urban trace gases, react via other reaction pathways than previously thought.

24 Feb 2021

Compounds from marine-derived fungus may protect cells from paraquat

Biologically active compounds from the marine fungus Penicillium dimorphosporum protect cells from paraquat, the highly toxic herbicide with no remedy, and might enhance the action of some drugs.

24 Feb 2021

Study reveals new therapeutic targets on SARS-CoV-2 Spike protein

Considering the recent COVID-19 pandemic, significant investigations are being made to find out how the SARS-CoV-2 Spike protein binds to a human cell.

23 Feb 2021

Study reveals link between group of metabolites in blood and satiety perception

Results of the European study SATIN (SATiety INnovation) reveal a relation between certain metabolites in the blood and the satiety perceived after consuming food.

23 Feb 2021

New gel electrophoresis method allows rapid diagnosis of biomarkers by mass spectrometry

Polyacrylamide gel electrophoresis is a technique that allows high-resolution isolation of proteins separated from biological specimens.

22 Feb 2021

Cryogenic electron microscopy reveals shape of glutamate transporters involved in neurological diseases

An international research team has uncovered the shape of the glutamate transporter and helps explain how the human brain cells interact with each other.

18 Feb 2021

Study reveals novel antibody binding implicated in liver and breast cancer

In the field of structural biology, certain molecules are so uncommon that they can only be captured with a special set of tools.

18 Feb 2021

Study identifies how CTLA-4 blockade can disable suppressive immune cells to aid tumor destruction

A Ludwig Cancer Research study has identified a novel mechanism by which a type of cancer immunotherapy known as CTLA-4 blockade can disable suppressive immune cells to aid the destruction of certain tumors.

18 Feb 2021

Protein imbalance leads to cataract

Cataracts are the most prevalent eye disease in humans. But despite this fact, the actual processes that lead to this disease are not entirely known.

17 Feb 2021

Study shows link between metabolic and cell division mechanisms

Several biological processes are subject to rhythmic variations. Popular examples of this include the supposed circadian rhythm.

17 Feb 2021

Study suggests a way to improve immunotherapy by altering immune cells’ access to sugar

Cancer cells and immune cells share something in common: They both love sugar. Sugar is an important nutrient. All cells use sugar as a vital source of energy and building blocks. For immune cells, gobbling up sugar is a good thing, since it means getting enough nutrients to grow and divide for stronger immune responses. But cancer cells use sugar for more nefarious ends.

17 Feb 2021

Combining cholesterol-lowering medications and lifestyle interventions may yield better benefits

Combining healthy lifestyle interventions reduces heart disease through beneficial effects on different lipoproteins and associated cholesterols, according to a study published February 9 in eLife.

17 Feb 2021

Potassium-independent cesium transporters in plants can help during nuclear power plant accidents

In recent time, HBO's highly acclaimed and award-winning miniseries Chernobyl highlighted the horror of nuclear power plant accident, which happened in Ukraine in 1986.

17 Feb 2021