Biochemistry

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Designing Compounds for Next-Gen Antibiotics and Cancer Treatments

Chemists at Cold Spring Harbor Laboratory (CSHL) have generated a novel set of molecular compounds and are evaluating them as possible candidates for novel drug discovery leads.

5 Apr 2024

Using Nanoparticles to Inactivate Multidrug-Resistant Bacteria

An article published in the Journal of Environmental Chemical Engineering describes a possible strategy for promoting selective inhibition of multidrug-resistant bacteria, which are increasingly abundant owing to the indiscriminate use of antibiotics and are therefore a major human health hazard.

4 Apr 2024

SARS-CoV-2 Variants Detected in Flood-Control Channels Near Homeless Encampments

To better understand COVID-19's spread during the pandemic, public health officials expanded wastewater surveillance.

4 Apr 2024

Development of a Rapid miRNA Detection Method Based on Rolling Circle Amplification

This study is led by Professor Jue Ruan (Chinese Academy of Agricultural Sciences, Shenzhen, China). The authors developed a one-pot isothermal detection method based on rolling circle amplification (RCA) for rapid and specific detection of miRNAs and short RNA fragments.

30 Mar 2024

Structural and Biochemical Mechanism of ALDH6A1 Uncovered

ALDH6A1, a member of the ALDH family, plays a crucial role in the catabolic pathways of valine and thymine. Dysregulation of ALDH6A1 expression has been linked to a variety of diseases.

30 Mar 2024

Promising Compound Shows Potential in Reducing Alcohol Consumption

Scripps Research scientists have found that LY2444296-;a compound that selectively blocks the kappa opioid receptor (KOP)-;may reduce drinking in cases of alcohol dependence in animal studies.

30 Mar 2024

Enzymatic Cocktail Outperforms Antibiotics Against Mycobacteria, Including TB

A recent study published in Microbiology Spectrum, a journal of the American Society for Microbiology, demonstrates that an enzymatic cocktail has the capability to eliminate various mycobacterial species of bacteria, including those responsible for tuberculosis.

28 Mar 2024

Artificial Glycocalyx-Based Method Detects Intact Bacteria

Each year, bacterial infections claim several million lives worldwide. That is why detecting harmful microorganisms is crucial – not only in the diagnosis of diseases but also, for example, in food production.

26 Mar 2024

New Study Unveils Mechanism Behind Mice Ovary Development

Scientists at the Francis Crick Institute have provided insight into the proteins governing the development of mice's ovaries both prenatally and postnatally. This might help comprehend the progression of female infertility.

25 Mar 2024

Novel Microfluidic Device for Rapid Plant Stress Diagnosis via miRNA Detection

In natural environments, plants encounter biotic and abiotic stresses that can significantly affect their productivity and health.

25 Mar 2024

Nature-Inspired Approach Accelerates Folding of Cysteine-Rich Peptides for Drug Discovery

Certain types of peptides and microproteins for drug discovery research can be made more efficiently and quickly using a reaction solvent that helps mimic nature's way.

25 Mar 2024

Drug Candidates Show Promise to Reverse HIV's Ability to Escape Immune System Detection

University of Pittsburgh School of Medicine scientists have identified drug candidates that show promise to reverse the ability of HIV to escape detection by the immune system.

20 Mar 2024

Study Reveals Neural Basis of Odor Perception

Scents, such as coffee, flowers, or freshly baked pumpkin pie, are created by odor molecules released by various substances and detected by our noses.

19 Mar 2024

Protein Fragments Uncover New Extremophiles, Aiding Alien Life Search

Microorganisms with perfect adaptations can survive in harsh settings, such as deep-sea tunnels and mountain peaks.

18 Mar 2024

Novel Molecule Targets Coronavirus and Boosts Antiviral Drug

Following the COVID-19 pandemic, researchers have been working hard to create antiviral medications and treatments.

15 Mar 2024

Study Reveals Key Role of STAP-1 in Immune Function

A recent study has illuminated the significance of the protein STAP-1 in activating specific immune cells.

13 Mar 2024

The Role of Vitamin A in the Pathogenesis of Psychiatric Disorders

A group of researchers in Newcastle has been investigating the part that vitamin A plays in the pathogenesis of psychiatric disorders.

12 Mar 2024

The Impact of Catalysis for Site-Specific Protein Modification

As they recently reported in the journal Nature Chemistry, Boston College researchers have developed a new tool that can be used to develop novel biotherapeutics and protein-based research tools: the ability to precisely modify proteins using a mild charge of electricity.

6 Mar 2024

UC Davis Researchers Identify a Promising New Fungicide to Fight Devastating Crop Diseases

A promising new fungicide to fight devastating crop diseases has been identified by researchers at the University of California, Davis.

1 Mar 2024

Cyanobacteria as a Key Ingredient in Sustainable Protein-Rich Foods

We all know that we ought to eat less meat and cheese and dig into more plant-based foods. But whilst perusing the supermarket cold display and having to choose between animal-based foods and more climate-friendly alternative proteins, our voices of reason don't always win.

28 Feb 2024

Biochemistry

Designing Compounds for Next-Gen Antibiotics and Cancer Treatments

Using Nanoparticles to Inactivate Multidrug-Resistant Bacteria

SARS-CoV-2 Variants Detected in Flood-Control Channels Near Homeless Encampments

Development of a Rapid miRNA Detection Method Based on Rolling Circle Amplification

Structural and Biochemical Mechanism of ALDH6A1 Uncovered

Promising Compound Shows Potential in Reducing Alcohol Consumption

Enzymatic Cocktail Outperforms Antibiotics Against Mycobacteria, Including TB

Artificial Glycocalyx-Based Method Detects Intact Bacteria

New Study Unveils Mechanism Behind Mice Ovary Development

Novel Microfluidic Device for Rapid Plant Stress Diagnosis via miRNA Detection

Nature-Inspired Approach Accelerates Folding of Cysteine-Rich Peptides for Drug Discovery

Drug Candidates Show Promise to Reverse HIV's Ability to Escape Immune System Detection

Study Reveals Neural Basis of Odor Perception

Protein Fragments Uncover New Extremophiles, Aiding Alien Life Search

Novel Molecule Targets Coronavirus and Boosts Antiviral Drug

Study Reveals Key Role of STAP-1 in Immune Function

The Role of Vitamin A in the Pathogenesis of Psychiatric Disorders

The Impact of Catalysis for Site-Specific Protein Modification

UC Davis Researchers Identify a Promising New Fungicide to Fight Devastating Crop Diseases

Cyanobacteria as a Key Ingredient in Sustainable Protein-Rich Foods

From Memory to Metaplasticity: Unraveling the Brain's Secrets

Revolutionizing Mass Spectrometry: A Deep Dive into Plasmion’s SICRIT® Technology

Expert Insights: HiMedia Labs on Advancing Nucleic Acid Extraction Across Industries

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