Cell Biology

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New Software Tool Helps Scientists Identify Aging Cells in Tissues

For human health, prematurely aging cells are a big problem. When a cell ages and stops growing, its function changes, which can cause or worsen cardiovascular disease, Alzheimer’s disease and other chronic diseases.

29 Apr 2025

Reciprocal Regulatory Link Between ecDNA Maintenance and DNA Damage Response Revealed

Extrachromosomal DNA (ecDNA) is a unique form of circular DNA that exists outside of normal chromosomes.

29 Apr 2025

Johns Hopkins Team Identifies Distinct Subtypes of Senescent Skin Cells

Senescent skin cells, often referred to as zombie cells because they have outlived their usefulness without ever quite dying, have existed in the human body as a seeming paradox, causing inflammation and promoting diseases while also helping the immune system to heal wounds.

29 Apr 2025

Chimpanzee Naive Stem Cells Reveal Evolutionary Clues to Human Development

Understanding how cells differentiate during early embryonic development is crucial for advancing regenerative medicine and developmental biology.

29 Apr 2025

Super Stem Cells Offer New Hope for IVF and Regenerative Medicine

The ‘super stem cells’ perform better than regular stem cells, being able to develop into many different cell types, researchers from the University of Copenhagen find, with many potential applications, including improved IVF treatment.

25 Apr 2025

Unraveling the Role of Long Noncoding RNAs in the Tumor Microenvironment

The tumor microenvironment (TME) is a complex and dynamic network consisting of tumor cells, immune cells, stromal cells, extracellular matrix (ECM), cytokines, and growth factors, all interacting to influence tumorigenesis, progression, and metastasis.

25 Apr 2025

Can Cells Hear? Study Finds Sound Alters Gene Activity and Blocks Fat Cell Development

Acoustic stimulation affects cell development and gene activity, revealing potential applications in biotechnology and obesity control through sound waves.

24 Apr 2025

Guinea Pig Modeling To Study Human Preimplantation and Embryogenesis

Research on guinea pig embryos uncovers similarities to human embryogenesis, advancing understanding of preimplantation stages and reproductive techniques.

23 Apr 2025

Likarda Paper Highlights Hydrogel Encapsulation with CSS Can Overcome Major Obstacle of Liver Cell Therapies

Likarda, a leading biotech company specializing in the development of enabling technologies for the delivery of both cell therapies and large molecule biologics, announced a new peer-reviewed publication that demonstrates a promising improvement in the effort to develop liver cell-based therapies for patients with chronic liver disease.

23 Apr 2025

DNA Organization Offers Clues for Advancing Stem Cell Therapy

Scientists at the University of California, Riverside, have discovered how adult stem cells retain their regenerative power. The researchers demonstrate in a paper published in the journal Genes & Development that these cells rely on a group of helper proteins called histone chaperones — organizers or guides known to help package our two-meter-long genome when cells need to divide or switch on specific genes.

22 Apr 2025

Study Reveals Direct Impact of Sound on Cellular Activity

The intense feeling one gets from powerful sounds, like a jet engine at takeoff or booming concert speakers, is not just in the head and ears – the cells might be sensing it too.

17 Apr 2025

Revealing Noise-Filtering in Basic Circadian Networks

New research has revealed that a simple circadian clock network possesses advanced noise-filtering capabilities, which improves the understanding of how biological circuits maintain accuracy in dynamic environmental contexts.

16 Apr 2025

Tolerogenic Dendritic Cells in Gut Prevent Allergic Reactions to Food

The immune system must be able to rapidly target invaders such as viruses while avoiding innocuous stimuli, or allergies may develop.

15 Apr 2025

Crucial Details in DNA Repair Processes

Researchers at the University of Birmingham have discovered answers that offer detail to explain two distinct DNA repair pathways that have long been debated.

15 Apr 2025

Smart Researchers Develop Novel UV and Machine Learning-Aided Method to Detect Microbial Contamination in Cell Cultures

Researchers from the Critical Analytics for Manufacturing Personalized-Medicine (CAMP), interdisciplinary research group (IRG) of Singapore-MIT Alliance for Research and Technology (SMART), MIT’s research enterprise in Singapore, in collaboration with Massachusetts Institute of Technology (MIT), A*STAR Skin Research Labs (A*SRL), and National University of Singapore (NUS), have developed a novel method that can quickly and automatically detect and monitor microbial contamination in cell therapy products (CTPs) early on during the manufacturing process.

15 Apr 2025

Novel Microscopy Reveals Two-Stage T-Cell Activation During Viral Infection

The research teams led by Wolfgang Kastenmüller and Georg Gasteiger utilized advanced microscopy techniques to investigate the activation and proliferation of specific immune cells, known as T-cells, during viral infections.

11 Apr 2025

Guinea Pigs as a Robust Model for Human Embryo Research

The initial days of human embryo development, referred to as pre-implantation, are crucial.

11 Apr 2025

New Standard Will Aid in High-Confidence Multiplication of Tissue Cells in Laboratories

ASTM International’s medical and surgical materials and devices (F04) will aid procedures for multiplying tissue cell cultivation in laboratory situations.

11 Apr 2025

Breakthrough Delivery System Advances CRISPR-Based Treatments

A research team from Helmholtz Munich and the Technical University of Munich has developed an advanced delivery system that transports gene-editing tools based on the CRISPR/Cas9 gene-editing system into living cells with significantly greater efficiency than before.

10 Apr 2025

Small Hatching Embryo may Improve the Chances of IVF Success

A new research paper was published in Aging (Aging-US) Volume 17, Issue 3, on March 5, 2025, titled "Reproductive aging, preimplantation genetic testing for aneuploidy, and the diameter of blastocysts: does size matter?"

10 Apr 2025