Cell Biology

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How Mitochondrial Damage Accelerates Stem Cell Aging

Hematopoietic stem cells (HSCs), the cells that produce all blood cell types, start to lose their efficacy as one ages, which eventually reduces the ability to maintain healthy blood and a robust immune system.

17 Apr 2026

MIT Chemists Discover How Membrane Lipids Drive Uncontrolled Cancer Cell Growth

Cells are enveloped by a lipid membrane that gives them structure and provides a barrier between the cell and its environment. However, evidence has recently emerged suggesting that these membranes do more than simply provide protection - they also influence the behavior of the protein receptors embedded in them.

17 Apr 2026

Neuronal Lipid Metabolism Plays a Key Role in Preventing Metabolic Disorders

The brain is the body's command centre, and neurons are the workhorses that carry out its commands. They transmit signals that regulate many bodily functions, including key metabolic processes such as appetite, body weight and energy expenditure.

17 Apr 2026

New Strategy Enables 3D Tissue Engineering Without the Use of Scaffolds

Biological tissues have a remarkable ability to organize and change shape, driven by forces generated by their own cells. One of the major challenges in bioengineering is harnessing this natural behavior to design synthetic living materials capable of adopting predetermined shapes. However, precisely controlling how a tissue behaves and directing its internal forces to adopt the desired shape remains a significant scientific challenge.

17 Apr 2026

Researchers Uncover How the Immune System Teaches the Brain to Avoid Toxins

Researchers from the University of Bonn and University Hospital Bonn uncover vital mechanism for survival.

17 Apr 2026

Scientists Uncover How "Sorting Hubs" Clear Damaged Proteins From Cells

Inside every cell, a cleanup operation runs around the clock. Proteins are constantly damaged by wear and tear. Some can be repaired, while others must be dismantled and recycled. When this system fails, damaged proteins accumulate in clumps associated with diseases such as Amyotrophic Lateral Sclerosis (ALS) and Frontotemporal Dementia.

16 Apr 2026

Researchers Develop 3D Organoids that Reflect the Complexity of Brain Tumors

Efforts to identify and evaluate next-generation therapeutics for pediatric brain tumors are easily stymied by the quality and availability of laboratory models for research. To address this issue, scientists at St. Jude Children's Research Hospital developed patient-derived tumor organoids and tumor organoid xenografts that accurately reflect the biologic underpinnings of embryonal brain tumors.

16 Apr 2026

"Zombie" Macrophages Accumulate in Aging Tissues and Diseased Livers

UCLA researchers have identified a rogue population of immune cells that quietly accumulates in aging tissues and in the livers of people with fatty liver disease. Clearing these cells, they found, dramatically reduced inflammation and reversed liver damage in mice - even while the animals remained on an unhealthy diet.

16 Apr 2026

Genetic Barcodes Reveal Early Origins of Human Peripheral Nerves

Millions of neurons branch throughout our bodies, keeping them in close communication with our brains. This peripheral network begins to take shape long before birth, as the cells of a growing embryo move into position and adopt their specialized roles.

15 Apr 2026

Brain Discovery Links Interhemispheric Communication to Spatial Memory

A team led by the Institute for Neurosciences (IN), a joint center of the Spanish National Research Council (CSIC) and Miguel Hernández University of Elche (UMH), has identified a brain circuit essential for spatial memory.

15 Apr 2026

Identifying Somatic Driver Mutations in Thyroid Autoimmune Disease

According to recent studies, immune cell DNA mutations that eliminate the immune system's natural brakes may be the cause of autoimmune disorders.

15 Apr 2026

Kinesin Motor Protein Variations Control Cargo Specificity in Neuronal Transport

Intracellular transport is a vital process that allows cells to move proteins and other molecules to specific locations.

13 Apr 2026

Early Epigenetic Changes and Gut Microbiome Interact to Shape Neurodevelopment

The gut microbiome and epigenetics-molecular switches that turn genes on or off-are intertwined, and both contribute to neurodevelopment, finds a study publishing April 10 in the Cell Press journal Cell Press Blue.

13 Apr 2026

Janelia Scientists Develop New Method To Study Blood-Brain Barrier Proteins

Think it was hard to get into Studio 54? Try getting through the blood-brain barrier.

10 Apr 2026

Study Reveals How Bacteria Protect Themselves During Cell Cleavage

Bacteria reproduce by dividing into two: they form a wall, or septum, between the two future cells while remodeling the old cell walls so the so-called "daughter" cells can separate without bursting.

10 Apr 2026

Low Oxygen Triggers Latent Regenerative Programs in Embryonic Mouse Limbs

Certain animals are able to regenerate missing body parts. After amputation, salamanders and frog tadpoles are able to reconstruct entire limbs. Mammals are unable to. Biologists have been trying to figure out why for decades.

10 Apr 2026

Single-Cell Mapping Uncovers Insights Into Pregnancy Complications

The biological connection between a pregnant woman and her developing baby has been mapped in unprecedented detail by UC San Francisco scientists, revealing new cell types and insights into conditions such as preeclampsia, preterm birth, and miscarriage.

9 Apr 2026