Cell Biology

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Study Uncovers Principles Guiding Replication Initiation Across the Human Genome

When cells proliferate, genomic DNA is precisely duplicated once per cell cycle. Abnormalities in this DNA replication process can cause alterations in genomic DNA, promoting cellular aging, cancer, and genetic disorders.

4 Dec 2025

Study Reveals How Cells Compensate for Missing Chromosomes

A hallmark of cancerous cells is an abnormal number of chromosomes or chromosome arms, known as aneuploidy.

4 Dec 2025

New Comprehensive Atlas Transforms Understanding of Neutrophil Diversity

Neutrophils are the most abundant immune cells in the body and the first to respond to infection or tissue damage.

4 Dec 2025

Single-Cell RNA Imaging Uncovers Four Distinct Neuron Bands in the Hippocampus

Researchers at the Mark and Mary Stevens Neuroimaging and Informatics Institute (Stevens INI) at the Keck School of Medicine of USC have identified a previously unknown pattern of organization in one of the brain's most important areas for learning and memory.

4 Dec 2025

Engineered Gut Bacteria With MiRNA Nanoparticles To Reverse IBD

Biomimetic nanoparticles delivering microRNA to gut bacteria enhance protective metabolites, repair intestinal barriers, and alleviate colitis symptoms.

3 Dec 2025

Light-Activated AR3 Triggers Alkalinity-Driven Apoptosis in Cancer Cells

One of the hallmarks of cancer cells is their ability to evade apoptosis, or programmed cell death, through changes in protein expression.

2 Dec 2025

Harnessing Triploid Loquat to Unlock Aneuploid Diversity for Advanced Breeding

Triploid plants are widely valued in horticulture for desirable traits such as seedlessness, yield improvement, and stress resilience.

2 Dec 2025

New Label-Free Breakthrough for Studying Bacterial Shape Diversity

Scientists have long known that bacteria come in many shapes and sizes, but understanding what those differences mean has remained a major challenge, especially for species that can't be grown in the lab.

2 Dec 2025

Study Reveals ATM-Driven Mechanism Behind Telomere-Induced Senescence

After a finite number of divisions, cells simply give up. As each round of replication trims their telomeres-the protective caps at the chromosome ends-those caps eventually become too short to prevent chromosome ends from being recognized as DNA breaks.

2 Dec 2025

New Insight Into Light-Guided Growth of Bristleworm Eyes

A new study, led by the University of Vienna and the Alfred Wegener Institute in Bremerhaven, shows how the eyes of adult marine bristleworms continue to grow throughout life – driven by a ring of neural stem cells reminiscent of vertebrate eyes.

2 Dec 2025

Hidden Messengers in the Blood

Every second, countless minute packages circulate through the bloodstream, transporting crucial data between the body’s cells.

1 Dec 2025

Study Identifies Adipogenin as Crucial Driver of Lipid Droplet Formation

A microprotein called adipogenin appears to play a key role in helping fat cells store lipid droplets – a phenomenon that's pivotal for metabolic health, a study co-led by UT Southwestern Medical Center researchers shows.

27 Nov 2025

Gene Transcription Start Sites Identified as Hidden Mutational Hotspots

Researchers have discovered new regions of the human genome particularly vulnerable to mutations. These altered stretches of DNA can be passed down to future generations and are important for how we study genetics and disease.

27 Nov 2025

Mitochondrial Mutation Found to Rewire Immune Function

Scientists have discovered how a mitochondrial mutation rewires immune function in a model of inherited primary mitochondrial disorders, which often lead to severe disability and death.

27 Nov 2025

Scientists Uncover Inner Workings of Biomolecular Condensates Linked to ALS

Inside the cell reside many tiny assembly factories and warehouses that gather together all of the proteins and RNAs-which carry out instructions from our DNA-that a living being needs.

27 Nov 2025

Scientists Map How Transcription Factors Interpret DNA Sequences

With a new study in the journal Cell, researchers at Stanford University and Stockholm University have contributed to increased knowledge about gene regulation in human cells.

27 Nov 2025

Breakthrough Reveals How Immune Cells Orchestrate Pathological Scarring

Researchers at the University of Arizona uncovered a previously unknown population of circulating immune cells that play a critical role in fibrosis, the buildup of scar tissue that can lead to organ failure and disfigurement.

26 Nov 2025

Discovery Reveals Unexpected Role for OTULIN in Controlling Tau Expression

Scientists have uncovered a surprising mechanism by which a brain enzyme called OTULIN controls the expression of tau, the protein that forms toxic tangles in Alzheimer's disease.

26 Nov 2025

Freezing Cells for Success: DMSO-Free Redefining the Future of Cryopreservation

Cryopreservation plays a crucial role in cell biology research, bioprocessing, and biomanufacturing. Traditionally, DMSO (dimethyl sulfoxide) has been the cryoprotectant of choice for preserving cells.

25 Nov 2025

Scientists Reveal How Memory T Cells Persist Across the Body

Memory T cells are a special type of white blood cell that "remember" past infections and vaccines, helping our bodies to quickly respond if we encounter the same germs again.

25 Nov 2025