Cell Biology

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Two subtypes of cells that produce insulin discovered

A team of scientists from the Van Andel Institute and the Max Planck Institute for Immunobiology and Epigenetics uncovered two unique subtypes of insulin-producing beta cells, or ß cells, each having important traits that could potentially be used to better understand and treat Type 1 and Type 2 diabetes.

30 Mar 2023

Artificial cells to serve as the powerhouse of the future

Chloroplasts and mitochondria are responsible for producing energy in nature, which is essential for creating sustainable, artificial cells in the lab. In addition to being “the powerhouses of the cell,” as the adage from middle school biology goes, mitochondria are also one of the most difficult intracellular components to artificially clone.

30 Mar 2023

Using better probiotics to maintain a healthy gut microbiome

Bacteria have thousands of genes and functions that we, the human host, do not have. For instance, bacteria can help us digest fiber, provide support to our immune systems, and absorb important nutrients. But reaping the benefits of "good bacteria" is easier said than done.

29 Mar 2023

Additional therapeutic maneuver may be needed to stop some metastasized tumors Cancer That...

Cancer that has spread to areas like the lungs can apply the brakes to a natural pathway that should recruit killer T cells directly to where it has metastasized, scientists report.

29 Mar 2023

Study provides a feasible tool to evaluate vesicular endocytosis of NPC1L1-cargos and cholesterol absorption

Excessive cholesterol absorption from intestinal lumen contributes to the pathogenesis of hypercholesterolemia, which is a well-established risk factor for atherosclerotic cardiovascular disease.

29 Mar 2023

3D cell culture system may be a valuable tool for assessing drug efficacy on tumor growth

Fibroblasts build and maintain the extracellular matrix, or physical scaffolding for cells, in the connective tissues within the body.

29 Mar 2023

The proper implementation of stem cell-based disease models

Scientists have learned how to manufacture induced pluripotent stem cells (iPSC) from regular cells through genetic reprogramming during the last ten years.

29 Mar 2023

Myeloid cells contribute to a long-lived HIV reservoir, study shows

A subset of white blood cells, known as myeloid cells, can harbor HIV in people who have been virally suppressed for years on antiretroviral therapy, according to findings from a small study supported by the National Institutes of Health.

28 Mar 2023

Human cells shed light on basic squid biology

Squids and octopuses are masters of camouflage, blending into their environment to evade predators or surprise prey.

28 Mar 2023

Finding how the global regulation factor reshapes the cell-fate-decision landscape

Determining cell differentiation trajectories has been done by genes and the regulation relationships among them creating complicated networks.

28 Mar 2023

Newest variant of mScarlet3 to help track protein movements in living cells

Biologists frequently utilize a method to figure out why a cell divides, secretes hormones, or sends a signal to another cell. They attach colored lights to the proteins of interest so that they can see their motions and interactions in living cells under a microscope.

28 Mar 2023

Monocytes harbor stable HIV DNA capable of infecting neighboring cells

To develop treatments that may one day entirely rid the body of HIV infection, scientists have long sought to identify all of the places that the virus can hide its genetic code.

28 Mar 2023

Scientists develop a detailed "protein atlas" of a pathogen for the first time

A parasite which has devasting impacts on agriculture and human health is the first pathogen to have its proteins located and mapped within its cells – providing clues to their function and helping to identify potential drug targets.

27 Mar 2023

Thickness of cancer cells' glycocalyx barrier determines immune cell evasion of tumors

One of the ways that cancer cells hide from the body's immune system is by forming a thin surface barrier called the glycocalyx.

27 Mar 2023

Potential therapeutic target in KRAS-mutant pancreatic cancer identified

A new research paper was published in Genes & Cancer on March 10, 2023, entitled, "VCP/p97, a pleiotropic protein regulator of the DNA damage response and proteostasis, is a potential therapeutic target in KRAS-mutant pancreatic cancer."

27 Mar 2023

Immune system’s aptitude in reducing reliance on antibiotics for treating infections

The removal of obsolete and damaged cell components by the body is crucial for fighting diseases like tuberculosis (TB), which establish themselves inside human cells, according to researchers from the Francis Crick Institute.

27 Mar 2023

Analyzing how the global regulation factor reshapes the cell-fate-decision landscape

Genes and their regulatory relationships form complex networks that govern cell differentiation trajectories. However, predicting and understanding cell fate decisions using bottom-up network topology is still side-lined.

27 Mar 2023

Understanding the cellular effects of antibiotics targeting cell wall biosynthesis

It is still unclear how antibiotics work to destroy bacteria. This knowledge, however, is required for the development of new antibiotics. That is exactly what is required because bacteria are becoming increasingly resistant to existing antibiotics.

27 Mar 2023

New findings could help target the causes of aging and cancer development

A protein complex prevents the repair of genome damage in human cells, in mice and in the nematode Caenorhabditis elegans, a team of researchers at the University of Cologne has discovered.

24 Mar 2023

Generating functional patient-specific thymic organoids from human pluripotent stem cells

Researchers have used pluripotent stem cells to make thymus organoids that support the development of patient-specific T-cells, researchers report March 23rd in the journal Stem Cell Reports.

24 Mar 2023

Cell Biology

Two subtypes of cells that produce insulin discovered

Artificial cells to serve as the powerhouse of the future

Using better probiotics to maintain a healthy gut microbiome

Additional therapeutic maneuver may be needed to stop some metastasized tumors Cancer That...

Study provides a feasible tool to evaluate vesicular endocytosis of NPC1L1-cargos and cholesterol absorption

3D cell culture system may be a valuable tool for assessing drug efficacy on tumor growth

The proper implementation of stem cell-based disease models

Myeloid cells contribute to a long-lived HIV reservoir, study shows

Human cells shed light on basic squid biology

Finding how the global regulation factor reshapes the cell-fate-decision landscape

Newest variant of mScarlet3 to help track protein movements in living cells

Monocytes harbor stable HIV DNA capable of infecting neighboring cells

Scientists develop a detailed "protein atlas" of a pathogen for the first time

Thickness of cancer cells' glycocalyx barrier determines immune cell evasion of tumors

Potential therapeutic target in KRAS-mutant pancreatic cancer identified

Immune system’s aptitude in reducing reliance on antibiotics for treating infections

Analyzing how the global regulation factor reshapes the cell-fate-decision landscape

Understanding the cellular effects of antibiotics targeting cell wall biosynthesis

New findings could help target the causes of aging and cancer development

Generating functional patient-specific thymic organoids from human pluripotent stem cells

How can the adoption of AI technology accelerate drug discovery?

Gaining insights into human disease biology through CRISPR platforms

Genome Editing Has A New Code

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