Cell Biology

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Discovery of Heme Transport Pathway Solves Longstanding Red Blood Cell Enigma

Scientists have long been puzzled by how maturing red blood cells manage to produce all the hemoglobin they need to carry oxygen to tissues, even after shedding the vital structures they need to produce it.

25 Apr 2026

Re-Engineering the Cellular Factory to Build a Better Delivery System for Gene Editors

Gene editing has emerged as a powerful approach for targeting the genetic causes of disease, but getting the editing machinery into the right cells efficiently, safely, and at the scale needed for therapies remains one of the biggest set of challenges in the field.

25 Apr 2026

Uncovering a Second Pathway for On-Demand Glycogen Regulation

Researchers at WEHI have uncovered a never-before-seen mechanism that human bodies utilize to control sugar. These discoveries redefine basic biological principles and pave the way for new scientific discoveries.

24 Apr 2026

Researchers Find COVID-19 Shifting Toward an Endemic Phase

The World Health Organization declared the global health emergency related to the COVID-19 pandemic over in 2023, as most people had developed immune protection against the virus through vaccination and/or prior infection.

23 Apr 2026

New VIS-Fbs Technology Offers Sharper Images of Living Cellular Processes

Fluorescent proteins have revolutionized science, enabling researchers to tag and visualize individual molecules in living cells, tissues, and animals.

23 Apr 2026

New Method Predicts Cancer Patient Outcomes at Single-Cell Resolution

Oregon Health & Science University researchers have developed a first-of-its-kind method to predict cancer patient survival using advanced molecular data from individual cells.

22 Apr 2026

New MIND Tool Enables Precise Control of Complex Microbiomes

University of California San Diego researchers have developed a new tool for understanding and modifying any microbiome, including the human microbiome.

22 Apr 2026

Brain Immune Cells Play Key Role in Glioblastoma Tumor Infiltration

Glioblastoma, the most common and most aggressive brain tumor type in adults, remains difficult to treat because it can infiltrate surrounding brain tissue and spread far beyond the main tumor.

22 Apr 2026

Epigenetic Regulators Shape Gene Activity in Unexpected Ways

A new study finds the proteins responsible for controlling which genes are expressed in a genome do more than simply turn a gene on or off.

21 Apr 2026

Stem Cell Model Reveals Mechanics of Early Human Embryo Development

For the first time, a stem cell model has produced a structure resembling an early human embryo with a yolk-sac-like structure, from a single starting stem cell population and without direct genetic manipulation.

21 Apr 2026

Physics Explains How Neural Tube Closure Occurs in Embryos

In about one out of every 1,000 pregnancies, the neural tube, a key nervous system structure, fails to close properly.

21 Apr 2026

Study Reveals How Neurons Sense Bacterial Signals in Nematodes

Neural interaction with bacteria, e.g. in the gut microbiome, has important effects on brains of animals from worms to people.

21 Apr 2026

RNA Network Controls Cell Wall Remodeling in Apple Embryogenesis

Somatic embryogenesis is a powerful route for plant regeneration, transformation, and breeding, but one major question has remained unresolved: how highly differentiated cells regain the capacity to divide and develop like embryos.

20 Apr 2026

Study Reveals the "Black Box" of Protein Quality Control in the ER

Over the past few years, Kivanç Birsoy of Rockefeller University and his colleagues in the Laboratory of Metabolic Regulation and Genetics have uncovered amazing information about the antioxidant glutathione, which has numerous vital functions in the body, including eliminating free radicals and repairing cellular damage.

20 Apr 2026

Protein Shape Changes Come Into Focus With LiP-MS and 3D Proteomics

This review explains how LiP-MS detects protein structural changes across whole proteomes, adding functional insight that standard abundance-based proteomics often misses. It also surveys method variants and shows how LiP-MS supports drug-target discovery, disease biomarker research, and the broader framework of “3D proteomics.”

20 Apr 2026

Next-Generation Mass Spectrometry Reveals How DIA Deepens Proteome Coverage

A multivendor comparison in a neonatal mouse model of bronchopulmonary dysplasia found that DIA, especially on next-generation platforms such as Orbitrap Astral and timsTOF Ultra, greatly expanded peptide and protein detection while preserving broad biological concordance. The deeper coverage improved subcellular and pathway annotation, increased differential protein detection, and reduced estimated sample-size needs, although platform-specific technical differences still complicated direct comparisons.

19 Apr 2026

How Mitochondrial Damage Accelerates Stem Cell Aging

Hematopoietic stem cells (HSCs), the cells that produce all blood cell types, start to lose their efficacy as one ages, which eventually reduces the ability to maintain healthy blood and a robust immune system.

17 Apr 2026

MIT Chemists Discover How Membrane Lipids Drive Uncontrolled Cancer Cell Growth

Cells are enveloped by a lipid membrane that gives them structure and provides a barrier between the cell and its environment. However, evidence has recently emerged suggesting that these membranes do more than simply provide protection - they also influence the behavior of the protein receptors embedded in them.

17 Apr 2026

Neuronal Lipid Metabolism Plays a Key Role in Preventing Metabolic Disorders

The brain is the body's command centre, and neurons are the workhorses that carry out its commands. They transmit signals that regulate many bodily functions, including key metabolic processes such as appetite, body weight and energy expenditure.

17 Apr 2026

New Strategy Enables 3D Tissue Engineering Without the Use of Scaffolds

Biological tissues have a remarkable ability to organize and change shape, driven by forces generated by their own cells. One of the major challenges in bioengineering is harnessing this natural behavior to design synthetic living materials capable of adopting predetermined shapes. However, precisely controlling how a tissue behaves and directing its internal forces to adopt the desired shape remains a significant scientific challenge.

17 Apr 2026