Cell Biology

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PAX3 Protein Plays Key Roles in Development and Cancer

Paired Box 3 (PAX3) is a protein that plays a critical role in the formation of tissues and organs during embryonic development and can positively (and less frequently, negatively) regulate gene expression.

19 Mar 2026

Molecular Switch Links Mitochondrial Stress to T Cell Exhaustion

Cancer-fighting T cells do not simply "run out of energy." They are molecularly reprogrammed.

19 Mar 2026

Psoriasis-Like Inflammation Limits Skin Cancer Growth

A study shows that psoriasis-like immune responses may limit skin cancer growth, challenging the view of chronic inflammation as solely tumor-promoting.

19 Mar 2026

Cancers Use Lipids Produced by Lung Cells to Support Metastatic Tumor Growth

Scientists from the VIB–KU Leuven Center for Cancer Biology, in collaboration with the Francis Crick Institute, have discovered how cancer cells can exploit healthy lung cells to support metastatic tumor growth in the lungs.

18 Mar 2026

'Spiderman' Cells Trap Viral Genomes With Sticky Protein Webs

Scientists have identified a cell defense mechanism that mimics Spiderman shooting his web to ensnare enemies.

18 Mar 2026

EV Engineering Boosts Drug Delivery and Improves Sepsis Survival

The engineered scaffold protein EN144 significantly improves extracellular vesicle therapies, showing potential in sepsis treatment and targeted drug delivery.

18 Mar 2026

Study Uncovers How "Selfish Chromosomes" Cheat the Rules of Genetic Inheritance

A new University of Utah-led study has discovered the mechanism behind a decades-old evolutionary mystery-how "selfish chromosomes" cheat the rules of genetic inheritance.

16 Mar 2026

New Ring Structure Guides Precise Cell Death and Immunity

Researchers at the University of Michigan have revealed that cells use a previously unknown feat of molecular craftsmanship to help protect their larger host organisms.

16 Mar 2026

Unexpected SRC Localization Offers Promising Target for Cancer Therapies

For five decades, scientists have known about a notorious cancer-causing enzyme called SRC. But they always assumed it only appeared on the inside of cells, where it sent signals that fueled tumor growth and stayed hidden from the immune system.

16 Mar 2026

4D Atlas Reveals Gene Activity During Embryo Development

How does a tiny cluster of cells become an embryo with a head, trunk, and tail? And how do thousands of genes coordinate this development? A new imaging method makes it possible to visualize the activity of thousands of genes simultaneously throughout the entire zebrafish embryo.

13 Mar 2026

NuSAP Protein Safeguards Centriole Structure During Cell Division

Biologists at the National University of Singapore (NUS) have uncovered how the protein NuSAP safeguards tiny structures inside cells called centrioles, revealing a mechanism linked to developmental disorders such as microcephaly and mosaic variegated aneuploidy (MVA) syndrome.

13 Mar 2026

Capsule Technology Enables Multi-Step Analysis of Individual Living Cells

Researchers have developed a capsule-based method that makes it possible to analyze the same cell through multiple experimental steps.

13 Mar 2026

New Method Reveals How Tumors Rewire Genetic Splicing Programs

Cancer is caused by faulty genes, but what also shapes a cancer cell's behaviour is how a gene's instructions are trimmed and rearranged before they are turned into the proteins that keep a cell alive.

13 Mar 2026

Comprehensive Brain Atlas Maps Epigenetic Changes During Aging

Neurodegenerative diseases affect more than 57 million people globally. The incidence of these diseases, from Alzheimer's to Parkinson's to ALS and beyond, is expected to double every 20 years.

13 Mar 2026

Dual Mechanism of Deep-Sea Sponge Compound Suppresses Cancer Cell Proliferation

A collaborative research team led by Professor Kaori Sakurai at Tokyo University of Agriculture and Technology, together with Associate Professor Hiroaki Itoh and Professor Masayuki Inoue at Graduate School of Pharmaceutical Sciences, the University of Tokyo, has uncovered a previously unknown mechanism of action of yaku'amide B, a structurally complex peptidic natural product derived from deep-sea sponge found in the waters near Yakushima Island, Japan.

12 Mar 2026

Functional Mitochondria Key to Recovery of Dying Photoreceptor Cells

Photoreceptors are specialized cells in the eye that convert light energy into neural signals.

12 Mar 2026

Newly Discovered Neurons Respond to Complex Spatial Frequencies

The visual cortex is the part of the brain that enables visual perception. In this area millions of nerve cells, called neurons, process stimuli from the outside world.

11 Mar 2026

Scientists Map Protein Landscape Driving Photosynthesis in Plant Cells

Research led by scientists at Washington State University has revealed insights on how plants form a microscopic landscape of proteins crucial to photosynthesis, the basis of Earth's food and energy chain.

11 Mar 2026

Study Reveals Microbiome Role in Protecting the Colon From Tissue Injury

The gut microbiome-the trillions of bacteria and other microbes that inhabit the gastrointestinal tract-drives a process vital for protecting the colon against tissue injury, according to the findings of a study co-led by Cedars-Sinai Health Sciences University investigators.

11 Mar 2026

Cardiff University Decodes Catastrophic DNA Rearrangement

Cardiff University researchers discovered how a particularly severe type of DNA damage occurs, giving fresh insight into mutation mechanisms that contribute to cancer and inherited genetic diseases.

11 Mar 2026