Cell Biology

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Synthetic Biology and Artificial Intelligence Transform the Discovery of Mysterious Orphan Receptors

A new review highlights how synthetic biology, AI, and spatial omics could transform ligand-receptor discovery from one-by-one searches into network-level mapping

23 May 2026

New 3D-Printed Trays Help Produce Functioning Human Gut Organoids Twice as Fast

Thanks to special 3D-printed scaffolding trays designed by experts at Cincinnati Children's, researchers can now produce larger versions of functional human gut organoids twice as fast as previous methods-and these organoids grow their own nerve cells.

23 May 2026

Researchers Use Yeast Sugar Molecules to Extend COVID Vaccine Immunity in Mice

In a new study published in Nature Immunology, researchers at Boston Children's Hospital demonstrated that pairing the original COVID-19 mRNA vaccine with an immune system enhancer, known as an adjuvant, extended the duration of the vaccine's protection in mice from a few months up to two years. The combo also showed a more pronounced response against omicron viral components than the vaccine alone.

23 May 2026

Essential Keratin Guides Embryonic Cell Movement in Developing Zebrafish

Hair, nails, and horns, all made up of keratin, are some of the hardest and most resilient structures in animals. Inside zebrafish cells, keratin plays a distinct role, giving them the strength they need to move together as a coherent tissue while modulating the driving forces behind their movement during early development. But what happens when keratin is missing?

22 May 2026

Ancient Eukaryotes Evolved on Oxygenated Seafloor Environments

From the highest mountains to the deepest ocean, the driest desert to the lushest jungle, Earth displays a dazzling array of lifeforms.

22 May 2026

Scientists Capture Live-Action Footage of Housekeeping Immune Cells Engulfing Melanoma

Scientists at the Garvan Institute of Medical Research have captured, for the first time, 'housekeeping' immune cells actively attacking and engulfing live melanoma cells – a discovery that could change the way we approach treatment for one of Australia's most common and deadly cancers.

22 May 2026

High Protein Levels Bypass Functional BRCA Defenses to Generate Toxic Double-Strand Genomic Breaks

When it comes to cancer, tumor suppressor genes are usually thought of as the "good guys." These genes make proteins that protect and repair DNA in cells.

22 May 2026

Dental Pulp Stem Cell Subsets Triggers Rapid Cellular Senescence and Tooth Decay

With age, teeth get increasingly brittle and susceptible to damage from tooth decay, which can eventually lead to tooth loss. Teeth have an intrinsic capability to regenerate, a process which is driven by dental pulp stem cells (DPSCs) which replenish the dental pulp including the dentin-producing cells called odontoblasts.

22 May 2026

Scientists Find Key Genetic Boundary That Dictates Immune System Failure

Not all broken genes fail in the same way: some simply stop working, while others interfere with what still works.

22 May 2026

Allison Institute Platform Utilizes Spatial Profiling to Locate Protective Cellular Niches

Researchers with the James P. Allison Institute™ at The University of Texas MD Anderson Cancer Center have discovered a new gene expression signature within tumors that can help identify patients with metastatic castration-resistant prostate cancer (mCRPC) who are more likely to experience lasting benefits from combined immunotherapy treatment.

21 May 2026

Researchers Discover That Lesion Cells Fail to Recruit Surrounding Tissue Into Tumor Growth Helpers

In an unexpected finding, a new study flips on its head researchers' understanding of how precancerous pancreas lesions evolve into pancreatic cancer. The paradigm-changing discovery has tremendous implications for identifying people at higher risk of cancer or even, potentially stopping malignant transformation.

21 May 2026

Polymer Platforms Help Focus Immune Attack on Cancerous Tumors

Conventional immune checkpoint inhibitors, such as anti-PD-1/PD-L1 and anti-CTLA-4 antibodies, can reinvigorate T cells but typically benefit less than 30% of patients.

21 May 2026

Disrupted Honeycomb Cellular Patterns in the Early Brain May Drive Cancer and Birth Defects

University of Virginia School of Medicine scientists have revealed how mistakes in the final step of cell division can have dire consequences for developing brain cells. The findings offer important new insights into cancer and developmental disorders, helping explain how the body tries to protect itself and what happens when it can't.

21 May 2026

Analysis Reveals Blurred Neural Patterns During Failed Cognitive Switches

Most people have experienced the feeling: switching from one task to another, only to find the brain momentarily stuck in the old mode of thinking. Sometimes, even after realizing a strategy no longer works, the mind keeps returning to it anyway.

21 May 2026

Open-Chip Design Separates Fluid Resistance From Wall Confinement to Trace Cell Behavior

Most cancer studies focus on chemical signals or stiff tumor surroundings, but the stickiness of the fluid itself has received little attention. For glioblastoma, the invasion front is about eight times more viscous than the necrotic core, creating a rising resistance that migrating cells must overcome.

21 May 2026

Protein Plays Dual Role by Silencing Thousands of Genes While Keeping Vital Ones Active

The causes of male infertility can be hard to diagnose, with many tests failing to detect genetic defects. Sometimes, infertility doesn't even involve the genes themselves. It can arise from improper folding of the father's DNA in the sperm. If a couple conceives, this mispackaged DNA can damage the lifelong health of the child.

21 May 2026

Engineers Develop New mRNA Adjuvant That Dramatically Amplifies Cancer-Fighting T Cells

Engineers from the University of Houston, MIT and Harvard have developed a new mRNA-based strategy that dramatically amplifies the T-cell response to vaccines - an advance that could lead to far more powerful cancer vaccines and stronger protection against infectious diseases.

20 May 2026

Sensory Nerve Signals Block the Immune System's Response to Lung Cancer

Researchers at the Francis Crick Institute have revealed that sensory nerve signals interfere with the immune system's response to lung cancer. This previously unrecognized neuroimmune connection could be targeted to improve responses to immunotherapy.

20 May 2026

Novel Synthetic Molecules Attack Cell Membranes to Prevent Severe Bacterial Infections

In a new study, researchers show how so‑called TriPcides can target the bacterium Staphylococcus aureus, including antibiotic‑resistant strains such as MRSA. The compounds disrupt the bacteria's ability to cause infection and can also kill dormant bacterial cells, which are often difficult to treat with existing antibiotics.

20 May 2026

Stimulating Early Brain Circuits Partially Restores Vocal Defects Caused by Genetic Mutations

Communication begins long before children learn to speak. Researchers at National Yang Ming Chiao Tung University (NYCU) in Taiwan have now uncovered how early brain activity helps build developing communication circuits via regulating FOXP2/Foxp2, a gene linked to human speech and communication disorders.

20 May 2026

Cell Biology

Synthetic Biology and Artificial Intelligence Transform the Discovery of Mysterious Orphan Receptors

New 3D-Printed Trays Help Produce Functioning Human Gut Organoids Twice as Fast

Researchers Use Yeast Sugar Molecules to Extend COVID Vaccine Immunity in Mice

Essential Keratin Guides Embryonic Cell Movement in Developing Zebrafish

Ancient Eukaryotes Evolved on Oxygenated Seafloor Environments

Scientists Capture Live-Action Footage of Housekeeping Immune Cells Engulfing Melanoma

High Protein Levels Bypass Functional BRCA Defenses to Generate Toxic Double-Strand Genomic Breaks

Dental Pulp Stem Cell Subsets Triggers Rapid Cellular Senescence and Tooth Decay

Scientists Find Key Genetic Boundary That Dictates Immune System Failure

Allison Institute Platform Utilizes Spatial Profiling to Locate Protective Cellular Niches

Researchers Discover That Lesion Cells Fail to Recruit Surrounding Tissue Into Tumor Growth Helpers

Polymer Platforms Help Focus Immune Attack on Cancerous Tumors

Disrupted Honeycomb Cellular Patterns in the Early Brain May Drive Cancer and Birth Defects

Analysis Reveals Blurred Neural Patterns During Failed Cognitive Switches

Open-Chip Design Separates Fluid Resistance From Wall Confinement to Trace Cell Behavior

Protein Plays Dual Role by Silencing Thousands of Genes While Keeping Vital Ones Active

Engineers Develop New mRNA Adjuvant That Dramatically Amplifies Cancer-Fighting T Cells

Sensory Nerve Signals Block the Immune System's Response to Lung Cancer

Novel Synthetic Molecules Attack Cell Membranes to Prevent Severe Bacterial Infections

Stimulating Early Brain Circuits Partially Restores Vocal Defects Caused by Genetic Mutations

The Future of Vision Restoration With ReVision Implant

How a Single List Is Changing Visibility for Women in Science

How Avatar Medical's 3D Technology Is Transforming How We Visualize the Human Body

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