Cell Biology

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Innovative OpenFISH Technique Enables Integrated Spatial Molecular Imaging in Tissues

Spatial transcriptomics (ST) shows which genes are being expressed and where within a tissue. Spatial metabolomics (SM), on the other hand, maps the location of metabolites—small molecules produced or used by cells—within tissue.

30 Sep 2026

Decoding the Mechanisms Behind Long-Term Epigenetic Gene Regulation Shifts

The transmission of biological traits from one generation to the next is generally attributed to DNA. But could some changes be passed on without altering the DNA sequence?

30 Sep 2026

Lifeblood, UQ and SMART CRC Pump New Life Into Lab-Grown Blood Production

Lifeblood researchers are among only a few research groups in the world who are already growing fully functional red blood cells from donor stem cells in the lab but producing them in quantities large enough for use in patients is inefficient and expensive.

29 Sep 2026

Targeted Y Chromosome Deletions Disrupt Key Cellular Immune Response Pathways

A new study found that cancer cells selectively chip away gene-rich sections of the Y chromosome, triggering ripples that regulate tumor growth.

29 Sep 2026

Oncogene-Induced Senescence Exhibits Dual Role in Tumor Suppression and Progression

Researchers at NYU Abu Dhabi have discovered that a single cancer-causing gene can trigger different responses in cells, with some helping to prevent tumors while others may contribute to their development.

29 Sep 2026

Study Establishes Immune Cell Trafficking as Viable Alzheimer's Target

There is no treatment available today to stop the death of brain cells in neurodegenerative diseases known as tauopathies, including Alzheimer's disease, in which twisted clumps of a protein called tau accumulate in the brain.

29 Sep 2026

Single-Cell Sequencing Confirms Epigenetic Remodeling Across Diverse Cardiac Cell Types

The adult human heart is a reliable and resilient engine fueling our everyday lives while also being responsive enough to supercharge a Usain Bolt sprint or sustain a three-week bike race in the French Alps and Pyrenees.

29 Sep 2026

New Insights Into How Toxoplasma Parasites Trigger Host Cell Invasion

Before the parasite Toxoplasma gondii can invade a cell, it has to know it has reached the right place. New research from the Whitehead Institute reveals that the parasite doesn't simply recognize a ready-made doorway into the cell. Instead, it helps create the conditions for its own entry.

28 Sep 2026

Post-Translational Modification Crosstalk Regulates Oncogenic Protein Stability and Activity

A review published in Genes & Diseases highlights the complex interplay between protein arginine methylation and ubiquitination, two forms of protein modification that can profoundly influence cancer development, progression and treatment response. The article brings together current understanding of how these interconnected molecular processes regulate proteins involved in cancer and identifies opportunities for future therapeutic approaches.

28 Sep 2026

AI Decodes Spatial DNA Packaging Patterns Invisible to Researchers

Aging progressively affects the functioning of our body and, among other things, deteriorates the ability of the hematopoietic system- the set of organs and tissues responsible for producing blood cells- to maintain adequate blood cell production.

28 Sep 2026

Engineered 3D miBrains Model Human Neurovascular Units and Pathology

Mount Sinai researchers have identified how APOE4, the strongest genetic risk factor for Alzheimer's disease, damages the brain's blood vessels and promotes the buildup of abnormal proteins linked to neurodegenerative disease.

26 Sep 2026

Individual Neurons Display Trial-to-Trial Firing Rate Variability Under Identical Visual Stimulation

Our brains internally represent the outside world through the coordinated activity of billions of neurons.

25 Sep 2026

Cryo-ET Reveals Native Membrane Architecture of Synchronous RyR1 Calcium Channels

Using cryo-electron microscopy, researchers at the Max Delbrück Center have revealed how muscle cell calcium channels open synchronously. The findings, published in "Nature Communications," may explain a mechanism behind serious muscle diseases.

25 Sep 2026

Cancer Cells Hijack Embryonic Repair Mechanisms to Seed Liver Metastases

Most colon cancer deaths are caused by the spread of tumor cells beyond the colon, usually to the liver. In a new study, MIT biologists identified a cellular pathway necessary for colorectal cancer metastasis.

25 Sep 2026

Multi-Receptor Blocking Achieves Superior Antifibrotic Response Over Single-Receptor Inhibition

Three adenosine receptor subtypes that normally send different signals were found to converge on a common pathway that activates cardiac fibroblasts, the scar-forming cells in the heart. Blocking the receptors together produced a much stronger antifibrotic effect than blocking them one at a time.

25 Sep 2026

Cell Biology

Innovative OpenFISH Technique Enables Integrated Spatial Molecular Imaging in Tissues

Decoding the Mechanisms Behind Long-Term Epigenetic Gene Regulation Shifts

Lifeblood, UQ and SMART CRC Pump New Life Into Lab-Grown Blood Production

Targeted Y Chromosome Deletions Disrupt Key Cellular Immune Response Pathways

Oncogene-Induced Senescence Exhibits Dual Role in Tumor Suppression and Progression

Study Establishes Immune Cell Trafficking as Viable Alzheimer's Target

Single-Cell Sequencing Confirms Epigenetic Remodeling Across Diverse Cardiac Cell Types

New Insights Into How Toxoplasma Parasites Trigger Host Cell Invasion

Post-Translational Modification Crosstalk Regulates Oncogenic Protein Stability and Activity

AI Decodes Spatial DNA Packaging Patterns Invisible to Researchers

Engineered 3D miBrains Model Human Neurovascular Units and Pathology

Individual Neurons Display Trial-to-Trial Firing Rate Variability Under Identical Visual Stimulation

Cryo-ET Reveals Native Membrane Architecture of Synchronous RyR1 Calcium Channels

Cancer Cells Hijack Embryonic Repair Mechanisms to Seed Liver Metastases

Multi-Receptor Blocking Achieves Superior Antifibrotic Response Over Single-Receptor Inhibition

Cancer-Associated Fibroblasts Construct Physical Barriers Limiting Antitumor T Cell Infiltration

Ultra-High-Resolution 3D Microscopy Captures Distinct Presynaptic Protein Organization States

Garvan Researchers Uncover Genetic Causes of Inherited Muscle Disease

Hotter Temperatures Cause Hidden Cellular Ageing in Wild Birds

Scientists Discover Why High Levels of the Amino Acid Cysteine Are Toxic to Cells

The Future of Vision Restoration With ReVision Implant

How a Single List Is Changing Visibility for Women in Science

How Avatar Medical's 3D Technology Is Transforming How We Visualize the Human Body

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