Cell Biology

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Immune Pathway Breakthrough Reveals Critical Sex Differences in Female Glioblastoma

Researchers have identified a critical biological difference in how glioblastoma develops in male and female laboratory models, pinpointing an immune pathway that fuels tumor growth only in females.

24 Jun 2026

Cryo-EM Imaging Uncovers the Structure of a Mysterious Molecular "Gate"

How large, fully folded proteins can pass through cell membranes without destroying them has long been one of the open questions in cell biology. Using cryo-electron microscopy (cryo‑EM), Leonid Sazanov and Ziyu Zhao at the Institute of Science and Technology Austria (ISTA) have now uncovered new details about a molecular "gate." Their findings were published in Molecular Cell.

23 Jun 2026

New Genetic Discovery Explains Why Colorectal Cancer Spreads so Quickly

Loss of GATA6-a transcription factor that controls which genes are turned on or off-can reprogram colorectal cancer cells into more primitive, adaptable states that can then spread to the liver and establish new tumors, according to Weill Cornell Medicine and Massachusetts Institute of Technology researchers.

23 Jun 2026

Scientists Discover Hidden Brain Development Signaling Pathway

The cytoskeleton gives cells their shape and helps them move. Researchers at Helmholtz Munich and the Ludwig Maximilian University now show that, in neural stem cells, proteins of the cytoskeleton are also found in the cell nucleus, where they can influence developmental programs.

23 Jun 2026

Scripps Research Identifies Erucamide Molecule as Shield Against Blindness

Many conditions that cause vision loss share a common feature: the gradual breakdown of the retina, the light-sensing tissue at the back of the eye.

23 Jun 2026

Decoding Hidden Metabolic Tissue Crosstalk via Advanced Proteomic Tracking

The body's organs are in constant communication. Fat tissue tells the liver when to store or release energy, the immune system signals localized inflammation, and thousands of proteins carry these messages to organs throughout the body.

23 Jun 2026

New Progenitor Cell Platform Offers Scalable Source for Immunotherapy

In a paper published in Cell, a USC Stem Cell-led team reports a new way of generating a renewable and expandable supply of the progenitor cells that give rise to macrophages.

22 Jun 2026

Targeting Iron Metabolism Offers a New Strategy to Kill Cancer Cells

Researchers from the University of Michigan Health Rogel Cancer Center have discovered a key metabolic pathway that allows colorectal cancer cells to accumulate large quantities of iron. Blocking that pathway reduced iron levels and caused the cancer cells to die.

22 Jun 2026

New Study Reveals How Introns Jump Between Species Without Viral Help

Jumping genes are parasites in the genetic material of bacteria, plants, animals and humans. They are released into the cell as small RNA molecules from ribonucleic acid (RNA) and possess complex mechanisms for inserting themselves into other parts of the genetic material within the cell, thereby often conferring new properties on the cell and thus accelerating evolution. There are also jumping genes that free themselves from the RNA using an RNA enzyme. These ribozymes or self-splicing introns are a special group of jumping genes.

22 Jun 2026

New Research Examines How Blood Cancer Mutations Progress from Healthy States

Researchers have found that a genetic mutation associated with a rare group of blood cancers does not always result in development of the disease. The work provides insight into the initial phases of the disease and may eventually lead to tailored monitoring techniques that improve patient outcomes.

22 Jun 2026

Scientists Find Weak Point in Bacteria Causing Severe Childhood Diarrhea

The bacteria enterotoxigenic E. coli and Shigella together cause hundreds of millions of infections each year and are among the leading causes of diarrheal death, especially in children. Decades of vaccine development efforts have come up short, in part because the usual vaccine targets vary too much from one strain to the next.

22 Jun 2026

Single-Cell Analysis Uncovers How Cancer Tumors Diversify and Resist Treatment

A comprehensive multi-cancer study from researchers at The University of Texas MD Anderson Cancer Center has revealed that cancer cells within tumors are genetically diverse, yet all carry the same core genetic changes that can be traced back to a common ancestral cell, providing a single-cell view of how tumors adapt, survive and diversify. Understanding this helps explain why some cancer cells manage to survive treatments, paving the way for more tailored diagnostic and therapeutic strategies.

22 Jun 2026

Artificial Intelligence Translates Raw Micro CT Scans Into 3D Virtual Stains

Rudolf Virchow fundamentally changed medicine when he formulated his cell theory of disease in the 19th century: diseases do not arise inexplicably within the organism, but rather in specific cells and tissues.

19 Jun 2026

Childhood Adversity Leaves Coordinated Epigenetic Marks Across Tissues

The experiences we face early in life may leave their marks on our health in ways that echo across decades-and even across the entire body.

19 Jun 2026

Taste and Smell Genetic Receptors Shape Long-Term Disease Risks

Imagine if a doctor could look at your DNA and predict not just your disease risk, but also which foods you're drawn to – and whether those cravings are quietly protecting you.

19 Jun 2026

CellTrap Technology Reveals Hidden Dynamics of Immune System Cancer Fighting

Established laboratory tests mainly capture average values across many cells and show, for example, how many cancer cells survive after contact with immune cells.

19 Jun 2026

Maternal Diet Fatty Acid Enriches Long Term Offspring Immune Health

Trans-vaccenic acid (TVA), the most abundant trans fatty acid found in human breast milk, helps boost immune system development and has long-lasting effects on immune system health in mice, according to a new study by researchers from the University of Chicago.

19 Jun 2026