Cell Biology

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Researchers Develop 3D Organoids that Reflect the Complexity of Brain Tumors

Efforts to identify and evaluate next-generation therapeutics for pediatric brain tumors are easily stymied by the quality and availability of laboratory models for research. To address this issue, scientists at St. Jude Children's Research Hospital developed patient-derived tumor organoids and tumor organoid xenografts that accurately reflect the biologic underpinnings of embryonal brain tumors.

16 Apr 2026

"Zombie" Macrophages Accumulate in Aging Tissues and Diseased Livers

UCLA researchers have identified a rogue population of immune cells that quietly accumulates in aging tissues and in the livers of people with fatty liver disease. Clearing these cells, they found, dramatically reduced inflammation and reversed liver damage in mice - even while the animals remained on an unhealthy diet.

16 Apr 2026

Genetic Barcodes Reveal Early Origins of Human Peripheral Nerves

Millions of neurons branch throughout our bodies, keeping them in close communication with our brains. This peripheral network begins to take shape long before birth, as the cells of a growing embryo move into position and adopt their specialized roles.

15 Apr 2026

Brain Discovery Links Interhemispheric Communication to Spatial Memory

A team led by the Institute for Neurosciences (IN), a joint center of the Spanish National Research Council (CSIC) and Miguel Hernández University of Elche (UMH), has identified a brain circuit essential for spatial memory.

15 Apr 2026

Identifying Somatic Driver Mutations in Thyroid Autoimmune Disease

According to recent studies, immune cell DNA mutations that eliminate the immune system's natural brakes may be the cause of autoimmune disorders.

15 Apr 2026

Kinesin Motor Protein Variations Control Cargo Specificity in Neuronal Transport

Intracellular transport is a vital process that allows cells to move proteins and other molecules to specific locations.

13 Apr 2026

Early Epigenetic Changes and Gut Microbiome Interact to Shape Neurodevelopment

The gut microbiome and epigenetics-molecular switches that turn genes on or off-are intertwined, and both contribute to neurodevelopment, finds a study publishing April 10 in the Cell Press journal Cell Press Blue.

13 Apr 2026

Janelia Scientists Develop New Method To Study Blood-Brain Barrier Proteins

Think it was hard to get into Studio 54? Try getting through the blood-brain barrier.

10 Apr 2026

Study Reveals How Bacteria Protect Themselves During Cell Cleavage

Bacteria reproduce by dividing into two: they form a wall, or septum, between the two future cells while remodeling the old cell walls so the so-called "daughter" cells can separate without bursting.

10 Apr 2026

Low Oxygen Triggers Latent Regenerative Programs in Embryonic Mouse Limbs

Certain animals are able to regenerate missing body parts. After amputation, salamanders and frog tadpoles are able to reconstruct entire limbs. Mammals are unable to. Biologists have been trying to figure out why for decades.

10 Apr 2026

Single-Cell Mapping Uncovers Insights Into Pregnancy Complications

The biological connection between a pregnant woman and her developing baby has been mapped in unprecedented detail by UC San Francisco scientists, revealing new cell types and insights into conditions such as preeclampsia, preterm birth, and miscarriage.

9 Apr 2026

Study Identifies Stemness Checkpoint Controlling Stem Cell Identity

A study published in Cell Research advances a central idea in stem cell biology by identifying a checkpoint that controls the identity of many different types of stem cells across developmental stages.

9 Apr 2026

CIPHER-seq Reveals RNA and Protein Activity in Immune Cells

A new single-cell technology is giving scientists their clearest view yet of immune cell behavior-capturing not just genetic intent but real-time activity.

9 Apr 2026

Mosaic Cell Reprogramming Primes Skin for Rapid Injury Response

It is well known that students who prepare in advance perform better on exams. Now, it appears that the skin can do the same.

9 Apr 2026

Study Reveals Microbiota Control of Intestinal Cell Plasticity

A research team led by scientists from the State University of Campinas (UNICAMP) in São Paulo, Brazil, has made significant progress in understanding the relationship between gut microbiota and intestinal cells.

8 Apr 2026

How Cancer Cells Evade Chemotherapy-Induced Apoptosis

Researchers at Umeå University have provided new insights into how cancer cells defend themselves against cell death.

8 Apr 2026

New Mouse Model Reveals Viral Path to Liver Cancer

Liver cancer is one of the world's deadliest cancers, and most cases are linked to chronic viral hepatitis. Yet scientists have lacked an animal model that faithfully recapitulates how the disease unfolds in people, from initial infection with a virus to liver inflammation, scarring, and cancer.

7 Apr 2026