Cell Biology

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Astrocyte abnormalities may play a pivotal role in causing ASD symptoms

Abnormalities in a type of brain cell called astrocytes may play a pivotal role in causing some behavioral symptoms of autism spectrum disorders, according to a preclinical study by Weill Cornell Medicine investigators.

22 Apr 2022

Researchers discover a protein that protects the pancreas from self-digestion

The pancreas secretes around a cup of digestive juices per day—a mixture of molecules capable of breaking down the food people consume.

22 Apr 2022

Manipulating immune cells to suppress the growth of some solid tumors

Cancer researchers at the Case Western Reserve University School of Medicine say they have successfully suppressed the growth of some solid tumors in research models by manipulating immune cells known as a macrophages.

21 Apr 2022

Extra copies of DNA explain insensitivity to chemotherapy in germ cell cancer

Extra copies of a piece of DNA partly explain insensitivity to chemotherapy in germ cell cancer, a new study shows.

21 Apr 2022

Researchers may have identified a key intermediate in the transition from prokaryotes to eukaryotes

All modern organisms fall into two classes, eukaryotes and prokaryotes. Eukaryotes (from the Greek meaning "true kernel") have a cell nucleus that harbors most of the cell's genetic information and includes organisms such as humans, plants and fungi.

20 Apr 2022

Research associates autophagy and age-related nervous system degradation

The in-built mechanism of recycling dead or poisonous material to preserve the health of human cells is critical to general health.

20 Apr 2022

Scientists reveal the origins and provide a detailed ID card of pancreatic endocrine stem cells

The pancreas is a key metabolic regulator. When pancreatic beta cells cease producing enough insulin, blood sugar levels rise dangerously — a phenomenon known as hyperglycemia — thus triggering diabetes.

20 Apr 2022

Microglia regulate the intrinsic excitability of neuronal subtypes differently

A new study reports that immune cell responses to bacteria affect the intrinsic excitability of rat neuronal subtypes differently.

20 Apr 2022

Study provides a deeper understanding of how gene mutations contribute to breast cancer progression

A mutated gene found in more than 20% to 30% of breast cancer recurrences may help tumors become more aggressive and promote metastasis, according to a pair of new studies that uncover mechanisms behind these processes and point to new therapy targets.

From University of Pittsburgh 20 Apr 2022

Stem cell-mediated gene therapy technique helps to boost bone regeneration

Mesenchymal stem cell-derived exosomes (MSC-Exo) have gained a lot of attention due to their “cell-free” treatments.

20 Apr 2022

Epigenetic regulator helps determine lung cancer patients and their resistance to drugs

Doctors commonly use tyrosine kinase inhibitors, particularly epidermal growth factor receptor inhibitors, to cure patients with non-small cell lung cancer, a common and typically deadly kind of cancer that accounts for 80% to 85% of lung cancers.

20 Apr 2022

Study highlights quality control pipeline method to analyze single-cell variation

When it comes to assessing the effects of endocrine-disrupting chemicals (EDCs) or toxins on cancers and other diseases, which target a variety of mechanisms, including the estrogen receptor (ER), one size does not always fit all.

20 Apr 2022

Rewiring the inner workings of leukemia cells to reverse drug resistance

Researchers from Barts Cancer Institute at Queen Mary University of London have identified a way to reverse resistance to a group of cancer drugs, known as kinase inhibitors, in leukemia cells.

20 Apr 2022

High performance microplates for enhanced cell growth and survival

The Sero Krystal™ PDL range of coated microplates from Porvair Sciences set a new benchmark for reproducible cell culture even with challenging cell types.

From Porvair Sciences Limited 20 Apr 2022

Researchers analyze the body’s immune cells with blood cancer cells

One in every two people will acquire cancer at some point in their lives, according to the most recent international estimate.

19 Apr 2022

New research shows significant variations in B-cells in women with PPD

Jerry Guintivano, PhD, of the University of North Carolina School of Medicine, led an exclusive transcriptome-wide association research that showed substantial changes in B-cells in women with postpartum depression, with pathway observations indicating modified B-cell activation and insulin resistance.

19 Apr 2022

Research associates depressive diseases and deformability of blood cells

For the first time, a study conducted by the TU Dresden and the University of Zurich in collaboration with the Max Planck Institute for the Science of Light finds a relationship between depressive disorders and mechanical features of all main blood cell types.

19 Apr 2022

Vitamin E can reinvigorate dendritic cells to enhance immunotherapy responses

Combining a retrospective analysis of clinical records with in-depth laboratory studies, researchers at The University of Texas MD Anderson Cancer Center have discovered that vitamin E can enhance immunotherapy responses by stimulating the activity of dendritic cells in the tumor.

18 Apr 2022

16 distinct cell populations identified in a key brain region for substance use disorders

In a work of systematic biology that advances the field, University of Alabama at Birmingham researchers have identified 16 distinct cell populations in a complex area of the midbrain called the ventral tegmental area, or VTA.

18 Apr 2022

AMN1: New gene target for antifungal therapy against cluster-forming pathogenic fungus

A recent study indicates that regulating and deleting a particular gene (AMN1) in yeast might lay the groundwork for a novel method of addressing drug resistance in microbial infections and cancer.

18 Apr 2022

Cell Biology

Astrocyte abnormalities may play a pivotal role in causing ASD symptoms

Researchers discover a protein that protects the pancreas from self-digestion

Manipulating immune cells to suppress the growth of some solid tumors

Extra copies of DNA explain insensitivity to chemotherapy in germ cell cancer

Researchers may have identified a key intermediate in the transition from prokaryotes to eukaryotes

Research associates autophagy and age-related nervous system degradation

Scientists reveal the origins and provide a detailed ID card of pancreatic endocrine stem cells

Microglia regulate the intrinsic excitability of neuronal subtypes differently

Study provides a deeper understanding of how gene mutations contribute to breast cancer progression

Stem cell-mediated gene therapy technique helps to boost bone regeneration

Epigenetic regulator helps determine lung cancer patients and their resistance to drugs

Study highlights quality control pipeline method to analyze single-cell variation

Rewiring the inner workings of leukemia cells to reverse drug resistance

High performance microplates for enhanced cell growth and survival

Researchers analyze the body’s immune cells with blood cancer cells

New research shows significant variations in B-cells in women with PPD

Research associates depressive diseases and deformability of blood cells

Vitamin E can reinvigorate dendritic cells to enhance immunotherapy responses

16 distinct cell populations identified in a key brain region for substance use disorders

AMN1: New gene target for antifungal therapy against cluster-forming pathogenic fungus

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