Cell Biology

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A Pair of Force-Activated Gene Regulating Proteins Guide Fetal Bone Development

A pair of proteins, YAP and TAZ, has been identified as conductors of bone development in the womb and could provide insight into genetic diseases such as osteogenesis imperfecta, known commonly as "brittle bone disease."

5 Jan 2024

Unraveling the Mysteries of COPII-Mediated Protein Transport

Similar to postal workers who deliver packages in inclement weather, such as snow, rain, or heat waves, a vital set of proteins found in mammals enables cells to operate normally, even in less-than-ideal circumstances.

4 Jan 2024

Zipping Up Chromosomes: The Synaptonemal Complex Revealed

We have two copies of each chromosome in every cell in our bodies except in our reproductive cells. Sperm and egg cells contain a single copy of each chromosome with a unique mix of genes from our parents, an evolutionary trick to give our offspring genetic variability.

4 Jan 2024

Improved Mapping of Small-Molecule Binding Sites in Cells

Researchers at Scripps Research created a novel, high-resolution method for identifying putative treatment targets on proteins in living cells.

3 Jan 2024

Unveiling Cytonemes, the Secret Messengers of the Nervous System

Researchers at St. Jude Children’s Research Hospital captured images of cytonemes, which are cellular projections that are involved in long-distance signal transmission during development.

3 Jan 2024

SPACEL: A Powerful AI Toolkit for Unveiling the 3D Secrets of Tissues

Spatial transcriptomics (ST) technologies are applied in biology and medical research for its ability to detect the spatial distribution of transcriptome in histological tissue slices.

3 Jan 2024

AI Tool Offers a Deep Dive Into Tissues, Boosting Cancer Detection and Treatment

A new artificial intelligence tool that interprets medical images with unprecedented clarity does so in a way that could allow time-strapped clinicians to dedicate their attention to critical aspects of disease diagnosis and image interpretation.

3 Jan 2024

Breakthrough in Synthetic Biology: Researchers Build Artificial CO2-Fixing Pathway

Synthetic biology offers the opportunity to build biochemical pathways for the capture and conversion of carbon dioxide (CO2).

3 Jan 2024

Researchers Identify Key Protein in Maintaining Two Organelles, Thereby Preventing Cellular Aging

Healthy organelles are essential to the operation of the cell, just as healthy organs are essential to human well-being.

2 Jan 2024

Mettl3 Drives Powerful Immune Defense of CD8 T Cells

This study is led by Dr. Shuyang Yu (College of Biological Sciences, China Agricultural University), Dr. Jingyu Xu (The Collaborative Innovation Center of Tissue Damage Repair and Regeneration Medicine of Zunyi Medical University) and Dr. Xuguang Du (College of Biological Sciences, China Agricultural University) and illustrated the key role of Mettl3 in CD8 T cell response during acute infection model.

2 Jan 2024

Study Provides a Systematic View of the Diversity and Function of Supraglacial DNA Viruses

Supraglacial environments mainly consist of four main types of habitats for microbes and viruses, including snow, ice, meltwater, and cryoconites (the granular sediment on glacier surfaces).

2 Jan 2024

The Foundation of Gene Expression in Brain Development

Researchers from Osaka University and Shenzhen Bay Laboratory have uncovered the actions of proteins connected to memory and learning in human brain cells in a study that was just published in Cell Reports.

29 Dec 2023

Zebrafish Embryo Model Unveils Breakthrough Cultivation Method

Researchers at the National University of Singapore (NUS) specializing in food virology have achieved successful cultivation of the human norovirus using zebrafish embryos.

29 Dec 2023

The Evolutionary Timeline of Diminished Boric Acid and Urea Transportation in Aquaporin 10

Aquaporin (Aqp) 10 water channels in humans allow the free passage of water, glycerol, urea, and boric acid across cells.

27 Dec 2023

Hyperglycemia Impairs Mitochondrial Function and Survival of Human Adipose Tissue-Derived MSCs

Mesenchymal stem cells (MSCs) are a type of stem cells that possess relevant regenerative abilities and can be used to treat many chronic diseases.

27 Dec 2023

ADSC-Exos and BMSC-Exos Protect Retinal Ganglion Cells From Hydrostatic Pressure Damage

Mesenchymal stem cells (MSCs) have protective effects on the cornea, lacrimal gland, retina, and photoreceptor cell damage, which may be mediated by exosomes (exos) released by MSCs.

27 Dec 2023

Xeno-Free Monkey PSC Culture System Enables Deriving, Tracking, and Differentiating Stem Cells

Non-human primates (NHPs) have a high degree of similarity to humans compared to other animal models.

26 Dec 2023

New Technique Revolutionizes the Construction of Synthetic Chromosomes

A groundbreaking new technique invented by researchers at the USC Dornsife College of Letters, Arts and Science may revolutionize the field of synthetic biology.

26 Dec 2023

Study Reveals Tissue-Specific Effects of JAK1 Signaling in Inflammation

Researchers at the Icahn School of Medicine at Mount Sinai have gained a deeper understanding of the nuanced roles of JAK inhibitors, or modulators, in inflammation across various cell types and tissues.

26 Dec 2023

Specialized Proliferative Cells Contribute to Epithelial Regeneration in Jellyfish

At about the size of a pinkie nail, the jellyfish species Cladonema can regenerate an amputated tentacle in two to three days -; but how? Regenerating functional tissue across species, including salamanders and insects, relies on the ability to form a blastema, a clump of undifferentiated cells that can repair damage and grow into the missing appendage.

26 Dec 2023

Cell Biology

A Pair of Force-Activated Gene Regulating Proteins Guide Fetal Bone Development

Unraveling the Mysteries of COPII-Mediated Protein Transport

Zipping Up Chromosomes: The Synaptonemal Complex Revealed

Improved Mapping of Small-Molecule Binding Sites in Cells

Unveiling Cytonemes, the Secret Messengers of the Nervous System

SPACEL: A Powerful AI Toolkit for Unveiling the 3D Secrets of Tissues

AI Tool Offers a Deep Dive Into Tissues, Boosting Cancer Detection and Treatment

Breakthrough in Synthetic Biology: Researchers Build Artificial CO2-Fixing Pathway

Researchers Identify Key Protein in Maintaining Two Organelles, Thereby Preventing Cellular Aging

Mettl3 Drives Powerful Immune Defense of CD8 T Cells

Study Provides a Systematic View of the Diversity and Function of Supraglacial DNA Viruses

The Foundation of Gene Expression in Brain Development

Zebrafish Embryo Model Unveils Breakthrough Cultivation Method

The Evolutionary Timeline of Diminished Boric Acid and Urea Transportation in Aquaporin 10

Hyperglycemia Impairs Mitochondrial Function and Survival of Human Adipose Tissue-Derived MSCs

ADSC-Exos and BMSC-Exos Protect Retinal Ganglion Cells From Hydrostatic Pressure Damage

Xeno-Free Monkey PSC Culture System Enables Deriving, Tracking, and Differentiating Stem Cells

New Technique Revolutionizes the Construction of Synthetic Chromosomes

Study Reveals Tissue-Specific Effects of JAK1 Signaling in Inflammation

Specialized Proliferative Cells Contribute to Epithelial Regeneration in Jellyfish

Expert Insights: HiMedia Labs on Advancing Nucleic Acid Extraction Across Industries

Quorum Bio: Where Synthetic Biology Meets Sustainable Farming

Diagnostic Biochips: Pioneering Brain Research Tools for the Future

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