Cell Biology

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Mitochondria Found to Play Key Role in Balancing Cell Death and Inflammatory Response

Whether cells in the human body survive or die under stress depends, among other things, on their mitochondria.

27 Nov 2024

Study Reveals Molecular Mechanism Behind Neural Fate Commitment

The Wistar Institute's Alessandro Gardini, Ph.D., and lab have shed new light on how certain biological processes determine the development of neural cells. Their findings on a molecular "bridge" complex demonstrate a new level of detail in the understanding of early neural development -; which is fundamental for the further understanding of neurodevelopmental syndromes.

27 Nov 2024

New Tool to Unravel the Secrets of Malaria Parasite Adhesion

To better understand the highly varied characteristics that enable malaria parasites to adhere to red blood cells and elude the immune system, researchers have developed a new tool.

27 Nov 2024

Unveiling the Epigenetic Landscape of Blood Cancers

In recent years, biomedical laboratory research has undergone tremendous change, to the extent that computers have frequently replaced test tubes.

27 Nov 2024

Promising New Target for Cancer Immunotherapy

Sensing infection and cellular change is essential for effective immunity. Human cells have a specialized chemical called MR1 on their surface.

27 Nov 2024

Single-Cell Analysis Sheds Light on Leukemia Cell Heterogeneity

Chromosomal instability plays a crucial role in the progression of cancer: it shapes the properties of tumor cells and drives the development of therapy resistance. Scientists from the German Cancer Research Center (DKFZ), the Heidelberg Stem Cell Institute HI-STEM and the European Molecular Biology Laboratory (EMBL) used state-of-the-art single-cell analysis methods to analyze the cellular heterogeneity of a specific form of acute myeloid leukemia.

26 Nov 2024

Locus Coeruleus Identified as Crucial for Maintaining Sleep Cycles

Researchers at the University of Lausanne have identified a novel role for the brain's 'locus coeruleus' in sleep and its disruptions.

26 Nov 2024

New Role for the Golgi Apparatus in Cancer Immunotherapy

The Golgi apparatus modifies, sorts, and packages proteins to be sent to their final destinations, whether that is within or outside of the cell.

25 Nov 2024

Cell Shape and Surface Stiffness Drive Distinct Migratory Behaviors in Ovarian Cancer Cells

The spread of tumor from the primary cancer site to distant organs, called metastasis, has puzzled scientists for many years – they are only now beginning to pinpoint triggers and mechanisms that drive this process.

25 Nov 2024

Unveiling the Hidden Potential of SnoRNAs

Dynamic, reversible modifications of DNA and RNA regulate how genes are expressed and transcribed, which can influence cellular processes, disease development, and overall organismal health.

25 Nov 2024

Unmasking the Molecular Mechanisms of Melanoma

LMU researchers have discovered how the interplay between a key protein and an endolysosomal ion channel promotes tumor development in skin cancer.

24 Nov 2024

Deep Neural Connections Drive Social Thought, Study Says

We've all been there. Moments after leaving a party, your brain is suddenly filled with intrusive thoughts about what others were thinking. "Did they think I talked too much?" "Did my joke offend them?" "Were they having a good time?"

24 Nov 2024

Rutgers Researchers Uncover How Brain Cells Form Functional Networks

Rutgers researchers at the Brain Health Institute (BHI) and Center for Advanced Human Brain Imaging Research (CAHBIR) have uncovered how different types of brain cells work together to form large-scale functional networks in the human brain – interconnected systems that support everything from sensory processing to complex decision-making – paving the way for new insights into brain health and disease.

23 Nov 2024

EPFL Brain Models Break New Ground in Understanding Neural Connectivity

The hippocampus is one of the most fascinating brain regions. Associated with the formation of memories, it also helps us to navigate through the world without getting lost.

23 Nov 2024

Human Cell Atlas Consortium Makes Major Progress in Understanding the Human Body

Researchers with the global Human Cell Atlas (HCA) consortium report significant progress in their quest for a better understanding of the cells of the human body in health and disease, with the publication today (20 November) of a Collection of more than 40 peer-reviewed papers in Nature and other Nature Portfolio journals.

22 Nov 2024

Mapping of Mouse Intestine Sheds Light on Immune Control and Adaptability

The intestine maintains a delicate balance in the body, absorbing nutrients and water while maintaining a healthy relationship with the gut microbiome, but this equilibrium is disrupted in parts of the intestine in conditions such as celiac disease, ulcerative colitis, and Crohn's disease.

22 Nov 2024

Chromosome Abnormalities Found in Healthy Women’s Breast Cells

A new study from researchers at The University of Texas MD Anderson Cancer Center finds that, in healthy women, some breast cells that otherwise appear normal may contain chromosome abnormalities typically associated with invasive breast cancer. The findings question conventional thinking on the genetic origins of breast cancer, which could influence early cancer detection methods.

22 Nov 2024